DE69333110T2 - Mit dem cytotoxin von helicobacter pylori assoziiertes, immunodominantes antigen verwendbar in impfstoffen und zur diagnose - Google Patents
Mit dem cytotoxin von helicobacter pylori assoziiertes, immunodominantes antigen verwendbar in impfstoffen und zur diagnose Download PDFInfo
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- DE69333110T2 DE69333110T2 DE69333110T DE69333110T DE69333110T2 DE 69333110 T2 DE69333110 T2 DE 69333110T2 DE 69333110 T DE69333110 T DE 69333110T DE 69333110 T DE69333110 T DE 69333110T DE 69333110 T2 DE69333110 T2 DE 69333110T2
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- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/35—Fusion polypeptide containing a fusion for enhanced stability/folding during expression, e.g. fusions with chaperones or thioredoxin
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/40—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/975—Kit
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- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Analytical Chemistry (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Engineering & Computer Science (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Physics & Mathematics (AREA)
- Immunology (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ITFI920052 | 1992-03-02 | ||
| ITFI920052A IT1262895B (it) | 1992-03-02 | 1992-03-02 | Proteina estratta da ceppi citotossici di helicobacter pylori, gene che la esprime, uso della proteina come vaccino o diagnostico. |
| WOPCT/EP93/00158 | 1993-01-25 | ||
| EPPCT/EP93/00158 | 1993-01-25 | ||
| PCT/EP1993/000472 WO1993018150A1 (en) | 1992-03-02 | 1993-03-02 | Helicobacter pylori proteins useful for vaccines and diagnostics |
Publications (2)
| Publication Number | Publication Date |
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| DE69333110D1 DE69333110D1 (de) | 2003-08-28 |
| DE69333110T2 true DE69333110T2 (de) | 2004-05-06 |
Family
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69333110T Expired - Lifetime DE69333110T2 (de) | 1992-03-02 | 1993-03-02 | Mit dem cytotoxin von helicobacter pylori assoziiertes, immunodominantes antigen verwendbar in impfstoffen und zur diagnose |
| DE69334197T Expired - Lifetime DE69334197T2 (de) | 1992-03-02 | 1993-03-02 | Helicobacter pylori Cytotoxin verwendbar in Impfstoffe und Diagnostik |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69334197T Expired - Lifetime DE69334197T2 (de) | 1992-03-02 | 1993-03-02 | Helicobacter pylori Cytotoxin verwendbar in Impfstoffe und Diagnostik |
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| EP (1) | EP0967279B1 (enExample) |
| JP (4) | JP3368902B2 (enExample) |
| AU (1) | AU3630093A (enExample) |
| CA (2) | CA2131729C (enExample) |
| DE (2) | DE69333110T2 (enExample) |
| WO (1) | WO1993018150A1 (enExample) |
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| CA2117490C (en) * | 1992-02-26 | 2009-01-06 | Timothy L. Cover | Purified vacuolating toxin from helicobacter pylori and methods to use same |
| US5928865A (en) * | 1992-03-02 | 1999-07-27 | Chiron S.P.A. | Compositions comprising isolated Helicobacter pylori CagI polynucleotides and method of preparation thereof |
| IT1262896B (it) * | 1992-03-06 | 1996-07-22 | Composti coniugati formati da proteine heat shock (hsp) e oligo-poli- saccaridi, loro uso per la produzione di vaccini. | |
| MX9301706A (es) * | 1992-04-13 | 1994-05-31 | Oravax Inc | Composicion de vacuna para el tratamiento de la infeccion por helicobacter. |
| US5403924A (en) * | 1992-10-13 | 1995-04-04 | Vanderbilt University | Taga gene and methods for detecting predisposition to peptic ulceration |
| US5733740A (en) * | 1992-10-13 | 1998-03-31 | Vanderbilt University | Taga gene and methods for detecting predisposition to peptic ulceration and gastric carcinoma |
| US6290962B1 (en) * | 1992-11-03 | 2001-09-18 | Oravax, Inc. | Urease-based vaccine and treatment for helicobacter infection |
| US5972336A (en) * | 1992-11-03 | 1999-10-26 | Oravax Merieux Co. | Urease-based vaccine against helicobacter infection |
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| US5997873A (en) * | 1994-01-13 | 1999-12-07 | Mount Sinai School Of Medicine Of The City University Of New York | Method of preparation of heat shock protein 70-peptide complexes |
| US5750119A (en) | 1994-01-13 | 1998-05-12 | Mount Sinai School Of Medicine Of The City University Of New York | Immunotherapeutic stress protein-peptide complexes against cancer |
| US5961979A (en) | 1994-03-16 | 1999-10-05 | Mount Sinai School Of Medicine Of The City University Of New York | Stress protein-peptide complexes as prophylactic and therapeutic vaccines against intracellular pathogens |
| GB2290710B (en) * | 1994-06-29 | 1998-03-25 | Reckitt & Colmann Prod Ltd | Protease from helicobacter pylori for use in vaccines/therapeutic compositions |
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| AU6343696A (en) * | 1995-07-07 | 1997-02-10 | Oravax, Inc | Helicobacter clpb |
| US5985270A (en) * | 1995-09-13 | 1999-11-16 | Fordham University | Adoptive immunotherapy using macrophages sensitized with heat shock protein-epitope complexes |
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| EP0797585A1 (fr) * | 1995-10-09 | 1997-10-01 | Pasteur Merieux Serums Et Vaccins | Recepteur lactoferrine d'helicobacter |
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| AU4311697A (en) * | 1996-09-20 | 1998-04-14 | Cortecs International Limited | Adhesins from heliobacter pylori and their diagnostic and therapeutic uses |
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| US5830464A (en) | 1997-02-07 | 1998-11-03 | Fordham University | Compositions and methods for the treatment and growth inhibition of cancer using heat shock/stress protein-peptide complexes in combination with adoptive immunotherapy |
| US6017540A (en) | 1997-02-07 | 2000-01-25 | Fordham University | Prevention and treatment of primary and metastatic neoplastic diseases and infectious diseases with heat shock/stress protein-peptide complexes |
| EP1017417A1 (en) * | 1997-04-30 | 2000-07-12 | Merieux OraVax SNC | ANTI-$i(HELICOBACTER) VACCINE COMPOSITION FOR USE BY THE SUBDIAPHRAGMATIC SYSTEMIC ROUTE, AND COMBINED MUCOSAL/PARENTERAL IMMUNIZATION METHOD |
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| AU2008299376B2 (en) | 2007-09-12 | 2013-02-28 | Glaxosmithkline Biologicals S.A. | GAS57 mutant antigens and GAS57 antibodies |
| NZ586430A (en) | 2007-12-21 | 2012-09-28 | Novartis Ag | Mutant forms of streptolysin o (slo) |
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| ATE122727T1 (de) | 1986-03-28 | 1995-06-15 | Univ Illinois | Zubereitungen und verfahren für klone, die, mit mehrfacharzneimittelresistenz assoziierte, dna- sequenzen in menschlichen zellen enthalten. |
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| FR2637612B1 (fr) * | 1988-10-06 | 1993-09-10 | Pasteur Institut | Sequences de nucleotides codant pour une proteine a activite ureasique |
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| GB8928625D0 (en) * | 1989-12-19 | 1990-02-21 | 3I Res Expl Ltd | H.pylori dna probes |
| US5292658A (en) * | 1989-12-29 | 1994-03-08 | University Of Georgia Research Foundation, Inc. Boyd Graduate Studies Research Center | Cloning and expressions of Renilla luciferase |
| ES2111589T3 (es) * | 1991-08-27 | 1998-03-16 | Hoffmann La Roche | Metodos y reactivos para la deteccion de la hepatitis c. |
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| US5721349A (en) * | 1992-02-26 | 1998-02-24 | Vanderbilt University | Vacuolating toxin-deficient H. pylori |
| IT1262895B (it) * | 1992-03-02 | 1996-07-22 | Proteina estratta da ceppi citotossici di helicobacter pylori, gene che la esprime, uso della proteina come vaccino o diagnostico. | |
| US5403924A (en) * | 1992-10-13 | 1995-04-04 | Vanderbilt University | Taga gene and methods for detecting predisposition to peptic ulceration |
| US5733740A (en) * | 1992-10-13 | 1998-03-31 | Vanderbilt University | Taga gene and methods for detecting predisposition to peptic ulceration and gastric carcinoma |
| US6019982A (en) * | 1994-08-26 | 2000-02-01 | The Administrators Of The Tulane Educational Fund | Mutant enterotoxin effective as a non-toxic oral adjuvant |
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| EP1282702B1 (en) * | 2000-05-10 | 2006-11-29 | Sanofi Pasteur Limited | Immunogenic polypeptides encoded by mage minigenes and uses thereof |
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- 1993-03-02 DE DE69333110T patent/DE69333110T2/de not_active Expired - Lifetime
- 1993-03-02 DE DE69334197T patent/DE69334197T2/de not_active Expired - Lifetime
- 1993-03-02 JP JP51530993A patent/JP3368902B2/ja not_active Expired - Lifetime
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- 1993-03-02 AU AU36300/93A patent/AU3630093A/en not_active Abandoned
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1995
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2005
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Also Published As
| Publication number | Publication date |
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| JP2006055168A (ja) | 2006-03-02 |
| WO1993018150A1 (en) | 1993-09-16 |
| DE69334197T2 (de) | 2008-12-11 |
| EP0967279B1 (en) | 2008-01-02 |
| DE69334197D1 (de) | 2008-02-14 |
| EP0967279A1 (en) | 1999-12-29 |
| CA2131729A1 (en) | 1993-09-16 |
| DE69333110D1 (de) | 2003-08-28 |
| JP3368902B2 (ja) | 2003-01-20 |
| US20050276819A1 (en) | 2005-12-15 |
| US6077706A (en) | 2000-06-20 |
| CA2131729C (en) | 2008-02-12 |
| CA2383007A1 (en) | 1993-09-16 |
| JP2000333686A (ja) | 2000-12-05 |
| US7700755B2 (en) | 2010-04-20 |
| JP3408494B2 (ja) | 2003-05-19 |
| US20040048353A1 (en) | 2004-03-11 |
| JPH07504565A (ja) | 1995-05-25 |
| JP2000350591A (ja) | 2000-12-19 |
| AU3630093A (en) | 1993-10-05 |
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