DE60316581D1 - 6-alkoxypyridopyrimidine als inhibitoren der p-38-map-kinase - Google Patents

6-alkoxypyridopyrimidine als inhibitoren der p-38-map-kinase

Info

Publication number
DE60316581D1
DE60316581D1 DE60316581T DE60316581T DE60316581D1 DE 60316581 D1 DE60316581 D1 DE 60316581D1 DE 60316581 T DE60316581 T DE 60316581T DE 60316581 T DE60316581 T DE 60316581T DE 60316581 D1 DE60316581 D1 DE 60316581D1
Authority
DE
Germany
Prior art keywords
alkoxypyridopyrimidines
inhibitors
map kinase
kinase
map
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE60316581T
Other languages
English (en)
Other versions
DE60316581T2 (de
Inventor
David Michael Goldstein
Julie Anne Lim
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of DE60316581D1 publication Critical patent/DE60316581D1/de
Application granted granted Critical
Publication of DE60316581T2 publication Critical patent/DE60316581T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
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  • Dermatology (AREA)
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  • Transplantation (AREA)
DE60316581T 2002-08-06 2003-07-29 6-alkoxypyridopyrimidine als inhibitoren der p-38-map-kinase Expired - Fee Related DE60316581T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US40149102P 2002-08-06 2002-08-06
US401491P 2002-08-06
PCT/EP2003/008357 WO2004014907A1 (en) 2002-08-06 2003-07-29 6-alkoxy-pyrido-pyrimidines as p-38 map kinase inhibitors

Publications (2)

Publication Number Publication Date
DE60316581D1 true DE60316581D1 (de) 2007-11-08
DE60316581T2 DE60316581T2 (de) 2008-07-03

Family

ID=31715709

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60316581T Expired - Fee Related DE60316581T2 (de) 2002-08-06 2003-07-29 6-alkoxypyridopyrimidine als inhibitoren der p-38-map-kinase

Country Status (15)

Country Link
US (4) US6965030B2 (de)
EP (1) EP1539755B1 (de)
JP (1) JP4252534B2 (de)
CN (1) CN100432073C (de)
AR (1) AR040787A1 (de)
AT (1) ATE374201T1 (de)
AU (1) AU2003251661A1 (de)
BR (1) BR0313297A (de)
CA (1) CA2492112A1 (de)
DE (1) DE60316581T2 (de)
ES (1) ES2293064T3 (de)
MX (1) MXPA05001332A (de)
PL (1) PL375403A1 (de)
RU (1) RU2324695C2 (de)
WO (1) WO2004014907A1 (de)

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BRPI0508036A (pt) 2004-02-27 2007-07-17 Hoffmann La Roche derivados fundidos de pirazola
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US20090221600A1 (en) * 2005-09-28 2009-09-03 Ashwani Kumar Verma Pyrido-pyridimidine derivatives useful as antiinflammatory agents
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ES2324083B1 (es) * 2007-10-22 2010-05-31 Consejo Superior De Investigaciones Cientificas Procedimiento para el diagnostico y tratamiento de enfermedades que cursan con alteracion de la quinasa p38, elementos necesarios para llevarlo a cabo y sus aplicaciones.
US8754114B2 (en) 2010-12-22 2014-06-17 Incyte Corporation Substituted imidazopyridazines and benzimidazoles as inhibitors of FGFR3
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US9388185B2 (en) 2012-08-10 2016-07-12 Incyte Holdings Corporation Substituted pyrrolo[2,3-b]pyrazines as FGFR inhibitors
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CN103145632B (zh) * 2013-03-26 2015-07-08 浙江普洛得邦制药有限公司 一种1h-1,2,4-三氮唑-3-甲酸甲酯的制备方法
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HRP20221196T1 (hr) 2017-10-05 2022-12-09 Fulcrum Therapeutics, Inc. Inhibitori p38 kinaze smanjuju ekspresiju dux4 i nizvodnih gena u cilju liječenja fshd
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