DE60236522D1 - G-csf konjugate - Google Patents

G-csf konjugate

Info

Publication number
DE60236522D1
DE60236522D1 DE60236522T DE60236522T DE60236522D1 DE 60236522 D1 DE60236522 D1 DE 60236522D1 DE 60236522 T DE60236522 T DE 60236522T DE 60236522 T DE60236522 T DE 60236522T DE 60236522 D1 DE60236522 D1 DE 60236522D1
Authority
DE
Germany
Prior art keywords
csf
conjugates
lysine residue
polypeptide
conjugated
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60236522T
Other languages
English (en)
Inventor
Torben Lauesgaard Nissen
Kim Vilbour Andersen
Christian Karsten Hansen
Jan Moeller Mikkelsen
Hans Thalsgaerd Schambye
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Maxygen Inc
Original Assignee
Maxygen Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27222576&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE60236522(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from US09/904,196 external-priority patent/US6555660B2/en
Application filed by Maxygen Inc filed Critical Maxygen Inc
Application granted granted Critical
Publication of DE60236522D1 publication Critical patent/DE60236522D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/53—Colony-stimulating factor [CSF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
    • A61K47/60—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
DE60236522T 2001-07-11 2002-07-10 G-csf konjugate Expired - Lifetime DE60236522D1 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US09/904,196 US6555660B2 (en) 2000-01-10 2001-07-11 G-CSF conjugates
DKPA200200447 2002-03-22
DKPA200200708 2002-05-08
PCT/DK2002/000482 WO2003006501A2 (en) 2001-07-11 2002-07-10 G-csf conjugates

Publications (1)

Publication Number Publication Date
DE60236522D1 true DE60236522D1 (de) 2010-07-08

Family

ID=27222576

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60236522T Expired - Lifetime DE60236522D1 (de) 2001-07-11 2002-07-10 G-csf konjugate

Country Status (16)

Country Link
US (4) US7550565B2 (de)
EP (1) EP1425304B9 (de)
JP (1) JP4444652B2 (de)
KR (1) KR100961859B1 (de)
AT (1) ATE468862T1 (de)
AU (1) AU2002325819B2 (de)
BR (1) BR0211071A (de)
CA (1) CA2452582C (de)
DE (1) DE60236522D1 (de)
HU (1) HUP0400466A3 (de)
IL (1) IL159524A0 (de)
MX (1) MXPA04000231A (de)
NO (1) NO20040093L (de)
NZ (1) NZ530545A (de)
PL (1) PL371781A1 (de)
WO (1) WO2003006501A2 (de)

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JP2005506317A (ja) 2005-03-03
MXPA04000231A (es) 2004-05-04
US20060286068A1 (en) 2006-12-21
NO20040093L (no) 2004-03-09
HUP0400466A3 (en) 2006-01-30
WO2003006501A3 (en) 2004-03-25
IL159524A0 (en) 2004-06-01
AU2002325819B2 (en) 2008-06-19
JP4444652B2 (ja) 2010-03-31
NZ530545A (en) 2006-10-27
HUP0400466A2 (hu) 2005-01-28
EP1425304B9 (de) 2010-09-08
US20060286069A1 (en) 2006-12-21
US20070010660A1 (en) 2007-01-11
KR100961859B1 (ko) 2010-06-09
WO2003006501A2 (en) 2003-01-23
PL371781A1 (en) 2005-06-27
US7550566B2 (en) 2009-06-23
CA2452582C (en) 2013-01-22
ATE468862T1 (de) 2010-06-15
US7696153B2 (en) 2010-04-13
EP1425304B1 (de) 2010-05-26
US7550565B2 (en) 2009-06-23
BR0211071A (pt) 2004-12-21
US20110020266A1 (en) 2011-01-27
CA2452582A1 (en) 2003-01-23
KR20040084884A (ko) 2004-10-06
EP1425304A2 (de) 2004-06-09

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