DE60228594D1 - Konstrukt aus kultivierten zellen mit spheroiden von kultivierten tierzellen und verwendung davon - Google Patents

Konstrukt aus kultivierten zellen mit spheroiden von kultivierten tierzellen und verwendung davon

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Publication number
DE60228594D1
DE60228594D1 DE60228594T DE60228594T DE60228594D1 DE 60228594 D1 DE60228594 D1 DE 60228594D1 DE 60228594 T DE60228594 T DE 60228594T DE 60228594 T DE60228594 T DE 60228594T DE 60228594 D1 DE60228594 D1 DE 60228594D1
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Prior art keywords
cultivated
cells
spheroids
construction
parenchymal cells
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Expired - Lifetime
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DE60228594T
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English (en)
Inventor
Kazunori Kataoka
Hidenori Otsuka
Teruo Okano
Yukio Nagasaki
Yasuhiro Horiike
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Transparent Inc
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Transparent Inc
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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/067Hepatocytes
    • C12N5/0671Three-dimensional culture, tissue culture or organ culture; Encapsulated cells
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0697Artificial constructs associating cells of different lineages, e.g. tissue equivalents
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2502/00Coculture with; Conditioned medium produced by
    • C12N2502/14Coculture with; Conditioned medium produced by hepatocytes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2502/00Coculture with; Conditioned medium produced by
    • C12N2502/28Vascular endothelial cells
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00Supports or coatings for cell culture, characterised by material
    • C12N2533/30Synthetic polymers
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2533/00Supports or coatings for cell culture, characterised by material
    • C12N2533/30Synthetic polymers
    • C12N2533/40Polyhydroxyacids, e.g. polymers of glycolic or lactic acid (PGA, PLA, PLGA); Bioresorbable polymers
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2535/00Supports or coatings for cell culture characterised by topography
    • C12N2535/10Patterned coating

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
DE60228594T 2001-07-26 2002-07-25 Konstrukt aus kultivierten zellen mit spheroiden von kultivierten tierzellen und verwendung davon Expired - Lifetime DE60228594D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2001226293 2001-07-26
PCT/JP2002/007539 WO2003010302A1 (fr) 2001-07-26 2002-07-25 Construction cellulaire cultivee contenant des spheroides de cellules animales cultivees et utilisation correspondante

Publications (1)

Publication Number Publication Date
DE60228594D1 true DE60228594D1 (de) 2008-10-09

Family

ID=19059133

Family Applications (2)

Application Number Title Priority Date Filing Date
DE60236974T Expired - Lifetime DE60236974D1 (de) 2001-07-26 2002-07-25 Kultiviertes Zellkonstrukt mit Sphäroiden kultivierter Tierzellen und seine Verwendung
DE60228594T Expired - Lifetime DE60228594D1 (de) 2001-07-26 2002-07-25 Konstrukt aus kultivierten zellen mit spheroiden von kultivierten tierzellen und verwendung davon

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE60236974T Expired - Lifetime DE60236974D1 (de) 2001-07-26 2002-07-25 Kultiviertes Zellkonstrukt mit Sphäroiden kultivierter Tierzellen und seine Verwendung

Country Status (9)

Country Link
US (2) US7470424B2 (de)
EP (2) EP1939280B1 (de)
JP (1) JP4111446B2 (de)
KR (1) KR100675533B1 (de)
CN (1) CN1798832B (de)
AT (1) ATE406436T1 (de)
CA (1) CA2454807C (de)
DE (2) DE60236974D1 (de)
WO (1) WO2003010302A1 (de)

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Also Published As

Publication number Publication date
US7470424B2 (en) 2008-12-30
JPWO2003010302A1 (ja) 2005-06-02
CN1798832B (zh) 2010-04-28
EP1939280B1 (de) 2010-07-07
EP1939280A1 (de) 2008-07-02
CA2454807C (en) 2012-09-18
US20090011504A1 (en) 2009-01-08
WO2003010302A1 (fr) 2003-02-06
JP4111446B2 (ja) 2008-07-02
EP1428871A1 (de) 2004-06-16
US20040197907A1 (en) 2004-10-07
US7691369B2 (en) 2010-04-06
ATE406436T1 (de) 2008-09-15
KR100675533B1 (ko) 2007-01-29
EP1428871B1 (de) 2008-08-27
CA2454807A1 (en) 2003-02-06
CN1798832A (zh) 2006-07-05
EP1428871A4 (de) 2004-11-24
DE60236974D1 (de) 2010-08-19
KR20040025700A (ko) 2004-03-24

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