ATE226966T1 - Polyethylenoxide mit einer saccharidgruppe an einem ende und einer anderen funktionellen gruppe am anderem ende sowie verfahren zu deren herstellung - Google Patents
Polyethylenoxide mit einer saccharidgruppe an einem ende und einer anderen funktionellen gruppe am anderem ende sowie verfahren zu deren herstellungInfo
- Publication number
- ATE226966T1 ATE226966T1 AT96909364T AT96909364T ATE226966T1 AT E226966 T1 ATE226966 T1 AT E226966T1 AT 96909364 T AT96909364 T AT 96909364T AT 96909364 T AT96909364 T AT 96909364T AT E226966 T1 ATE226966 T1 AT E226966T1
- Authority
- AT
- Austria
- Prior art keywords
- denotes
- polymer
- group
- oligomer
- functional group
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
- C08G65/02—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
- C08G65/32—Polymers modified by chemical after-treatment
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L71/00—Compositions of polyethers obtained by reactions forming an ether link in the main chain; Compositions of derivatives of such polymers
- C08L71/02—Polyalkylene oxides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
- A61K47/59—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes
- A61K47/60—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyureas or polyurethanes the organic macromolecular compound being a polyoxyalkylene oligomer, polymer or dendrimer, e.g. PEG, PPG, PEO or polyglycerol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
- A61K47/6905—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a colloid or an emulsion
- A61K47/6907—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit the form being a colloid or an emulsion the form being a microemulsion, nanoemulsion or micelle
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G63/00—Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
- C08G63/66—Polyesters containing oxygen in the form of ether groups
- C08G63/664—Polyesters containing oxygen in the form of ether groups derived from hydroxy carboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
- C08G65/02—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
- C08G65/26—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring from cyclic ethers and other compounds
- C08G65/2603—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring from cyclic ethers and other compounds the other compounds containing oxygen
- C08G65/2606—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring from cyclic ethers and other compounds the other compounds containing oxygen containing hydroxyl groups
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G65/00—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule
- C08G65/02—Macromolecular compounds obtained by reactions forming an ether link in the main chain of the macromolecule from cyclic ethers by opening of the heterocyclic ring
- C08G65/32—Polymers modified by chemical after-treatment
- C08G65/329—Polymers modified by chemical after-treatment with organic compounds
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T428/00—Stock material or miscellaneous articles
- Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
- Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
- Y10T428/2984—Microcapsule with fluid core [includes liposome]
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T428/00—Stock material or miscellaneous articles
- Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
- Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
- Y10T428/2984—Microcapsule with fluid core [includes liposome]
- Y10T428/2985—Solid-walled microcapsule from synthetic polymer
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP8937395 | 1995-04-14 | ||
PCT/JP1996/001020 WO1996032434A1 (fr) | 1995-04-14 | 1996-04-12 | Oxydes de polyethylene ayant un groupe saccharide a une extremite et un groupe fonctionnel different a l'autre extremite, et procede pour produire lesdits oxydes de polyethylene |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE226966T1 true ATE226966T1 (de) | 2002-11-15 |
Family
ID=13968897
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT96909364T ATE226966T1 (de) | 1995-04-14 | 1996-04-12 | Polyethylenoxide mit einer saccharidgruppe an einem ende und einer anderen funktionellen gruppe am anderem ende sowie verfahren zu deren herstellung |
Country Status (20)
Country | Link |
---|---|
US (2) | US5973069A (de) |
EP (1) | EP0852243B1 (de) |
JP (1) | JP4036472B2 (de) |
KR (1) | KR19990007804A (de) |
CN (1) | CN1085690C (de) |
AT (1) | ATE226966T1 (de) |
AU (1) | AU5289096A (de) |
BR (1) | BR9604895A (de) |
CA (1) | CA2218140A1 (de) |
DE (1) | DE69624581T2 (de) |
DK (1) | DK0852243T3 (de) |
ES (1) | ES2185769T3 (de) |
HU (1) | HU221090B1 (de) |
MX (1) | MX9707887A (de) |
NO (1) | NO974728L (de) |
NZ (1) | NZ304991A (de) |
PT (1) | PT852243E (de) |
RU (1) | RU2193574C2 (de) |
SI (1) | SI9620064A (de) |
WO (1) | WO1996032434A1 (de) |
Families Citing this family (48)
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US6133347A (en) * | 1999-07-09 | 2000-10-17 | Mbt Holding Ag | Oligomeric dispersant |
US6861459B2 (en) * | 1999-07-09 | 2005-03-01 | Construction Research & Technology Gmbh | Oligomeric dispersant |
US6908955B2 (en) * | 1999-07-09 | 2005-06-21 | Construction Research & Technology Gmbh | Oligomeric dispersant |
JP2001048978A (ja) | 1999-08-04 | 2001-02-20 | Nano Career Kk | オキサゾリン由来のポリマーセグメントを有するブロックコポリマー |
JP2001208754A (ja) * | 2000-01-26 | 2001-08-03 | Kazunori Kataoka | 生物学的な被検体を検出するための組成物 |
JP2001247591A (ja) * | 2000-03-02 | 2001-09-11 | Natl Inst Of Advanced Industrial Science & Technology Meti | 重合性グルコフラノース誘導体およびその製造方法 |
EP1279959A4 (de) * | 2000-05-11 | 2006-07-05 | Toudai Tlo Ltd | Polymerzusammensetzung zum bilden von oberflächen für biosensoren |
JP4063510B2 (ja) * | 2001-07-13 | 2008-03-19 | ナノキャリア株式会社 | 薬物含有高分子ミセルの凍結乾燥用組成物およびその凍結乾燥製剤 |
DE60236974D1 (de) | 2001-07-26 | 2010-08-19 | Transparent Inc | Kultiviertes Zellkonstrukt mit Sphäroiden kultivierter Tierzellen und seine Verwendung |
ATE376020T1 (de) | 2001-08-22 | 2007-11-15 | Bioartificial Gel Technologies Inc | Verfahren zu herstellung von aktivierten polyethylenglykolen |
JPWO2003076933A1 (ja) * | 2002-03-11 | 2005-07-28 | 株式会社東京大学Tlo | 増大した密度のポリ(エチレンオキシド)のブラシ様構造表面 |
ATE385239T1 (de) * | 2002-05-08 | 2008-02-15 | Medical Enzymes Ag | Schutzreagenzien enthaltend aktive kohlenhydrate für chemische modifizierungen, dessen herstellung und verwendung |
WO2005073370A1 (ja) * | 2004-01-31 | 2005-08-11 | Transparent Inc. | 酵素複合体 |
US7351787B2 (en) * | 2004-03-05 | 2008-04-01 | Bioartificial Gel Technologies, Inc. | Process for the preparation of activated polyethylene glycols |
EP2656840B1 (de) | 2005-06-09 | 2015-09-16 | NanoCarrier Co., Ltd. | Verfahren zur Herstellung polymerisierter Koordinations-Platinkomplexverbundstoffe |
US8592385B2 (en) | 2006-03-01 | 2013-11-26 | The University Of Tokyo | Polymer micelle complex including nucleic acid |
JPWO2007102608A1 (ja) * | 2006-03-06 | 2009-07-23 | ナノキャリア株式会社 | 疎水性化合物の安定化剤 |
CA2650422A1 (en) * | 2006-04-24 | 2007-11-08 | Nanocarrier Co., Ltd. | Process for producing polymer micelles encapsulating low molecular weight drugs |
CA2658082C (en) | 2006-07-18 | 2015-03-17 | Nanocarrier Co., Ltd. | Physiologically active polypeptide- or protein-encapsulating polymer micelles, and method for production of the same |
US8153110B2 (en) | 2006-11-22 | 2012-04-10 | The University Of Tokyo | Environment-responding siRNA carrier using disulfide-cross-linked polymeric micelle |
US20080161535A1 (en) * | 2006-12-21 | 2008-07-03 | Wiggins Michael S | Thickening and wetting agents |
JP5661460B2 (ja) * | 2007-07-12 | 2015-01-28 | ビーエーエスエフ ソシエタス・ヨーロピアBasf Se | ニトロセルロースベースの分散剤 |
US8075909B2 (en) | 2007-09-04 | 2011-12-13 | University Of Florida Research Foundation, Incorporated | Contact lens based bioactive agent delivery system |
JP5645186B2 (ja) | 2008-04-30 | 2014-12-24 | 国立大学法人 東京大学 | 電荷変換型三元系ポリプレックス |
PL2305275T3 (pl) | 2008-06-24 | 2013-12-31 | Nanocarrier Co Ltd | Ciekła kompozycja zawierająca koordynacyjny związek cisplatyny |
CA2728960C (en) | 2008-06-26 | 2016-04-12 | Japan Science And Technology Agency | Polymer-metal complex composite having mri contrast ability and mri contrasting and/or antitumor composition using the same |
JPWO2011021398A1 (ja) * | 2009-08-21 | 2013-01-17 | 出光興産株式会社 | 重合性基を有する糖誘導体及びそれを用いたレジスト材料 |
JP2013507365A (ja) | 2009-10-07 | 2013-03-04 | サンフォード−バーナム メディカル リサーチ インスティテュート | 血餅結合脂質化合物に関する方法および組成物 |
JP4829351B2 (ja) | 2010-02-05 | 2011-12-07 | ナノキャリア株式会社 | 易崩壊型ポリマーミセル組成物 |
US20110262347A1 (en) | 2010-04-08 | 2011-10-27 | The Salk Institute For Biological Studies | Methods and compositions for enhanced delivery of compounds |
WO2011145745A1 (ja) | 2010-05-21 | 2011-11-24 | 独立行政法人科学技術振興機構 | 物質内包ベシクル及びその製造方法 |
WO2012005376A1 (ja) | 2010-07-09 | 2012-01-12 | 国立大学法人 東京大学 | 核酸送達用組成物及び担体組成物、それを用いた医薬組成物、並びに核酸送達方法 |
WO2012118778A1 (en) | 2011-02-28 | 2012-09-07 | Sanford-Burnham Medical Research Institute | Truncated car peptides and methods and compositions using truncated car peptides |
US10179801B2 (en) | 2011-08-26 | 2019-01-15 | Sanford-Burnham Medical Research Institute | Truncated LYP-1 peptides and methods and compositions using truncated LYP-1 peptides |
RU2538211C2 (ru) * | 2012-09-12 | 2015-01-10 | Федеральное государственное бюджетное учреждение науки Институт высокомолекулярных соединений Российской академии наук | Способ получения углеводсодержащих полимеров |
JP6049854B2 (ja) | 2013-03-01 | 2016-12-27 | 国立研究開発法人科学技術振興機構 | 物質内包ベシクル及びその製造方法 |
CN105121506B (zh) * | 2013-03-25 | 2017-03-08 | 日油株式会社 | 具有苯亚甲基缩醛连接基团的亲水性聚合物衍生物 |
CN105377302B (zh) | 2013-05-17 | 2018-05-11 | 那野伽利阿株式会社 | 聚合物胶束医药组合物 |
JP2015046867A (ja) | 2013-07-31 | 2015-03-12 | 株式会社リコー | 撮像装置 |
JP6108369B2 (ja) | 2013-08-06 | 2017-04-05 | 国立研究開発法人科学技術振興機構 | 核酸内包高分子ミセル複合体及びその製造方法 |
JP6145612B2 (ja) | 2013-08-23 | 2017-06-14 | 国立大学法人 東京大学 | 高分子ナノ粒子複合体、及びそれを含むmri造影用組成物 |
JP5971264B2 (ja) | 2014-01-10 | 2016-08-17 | Jfeスチール株式会社 | 極厚肉油井管用ねじ継手 |
US10500246B2 (en) | 2015-06-25 | 2019-12-10 | Sanford Burnham Prebys Medical Discovery Institute | Compositions for delivery to and treatment of atherosclerotic plaques |
DE102017003004A1 (de) * | 2017-03-23 | 2018-09-27 | Friedrich-Schiller-Universität Jena | Kationische Polymere mit D-Fructose-Substituenten |
WO2018204392A1 (en) | 2017-05-02 | 2018-11-08 | Stanford Burnham Prebys Medical Discovery Institute | Tumor associated monocyte/macrophage binding peptide and methods of use thereof |
CN113490681A (zh) | 2019-02-04 | 2021-10-08 | 塔图大学 | 双特异性胞外基质结合肽及其使用方法 |
EP3808757A1 (de) | 2019-10-14 | 2021-04-21 | École Polytechnique Fédérale de Lausanne (EPFL) | Erneuerbares monomer und polymer davon |
CN112029084B (zh) * | 2020-08-31 | 2021-10-26 | 华南理工大学 | 一种以硫代羧酸为引发剂简便、可控合成α-巯基-ω-羟基聚醚的方法 |
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DE3163056D1 (en) * | 1980-06-20 | 1984-05-17 | Goldschmidt Ag Th | Process for the production of polymers with at least one terminal primary hydroxyl group |
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US5037969A (en) * | 1986-07-03 | 1991-08-06 | Takeda Chemical Industries, Ltd. | Glycosyl derivatives and use thereof |
JPS63152393A (ja) * | 1986-07-03 | 1988-06-24 | Takeda Chem Ind Ltd | グリコシル誘導体 |
EP0442804B1 (de) * | 1990-02-14 | 1996-08-28 | Elf Atochem S.A. | Funktionalisierte Multiblockmakromonomere und Verfahren zur Herstellung |
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DE4313117C2 (de) * | 1993-04-22 | 1995-09-28 | Grillo Werke Ag | Fettsäureester von Methylglukosid-Derivaten, Verfahren zu ihrer Herstellung und Verwendung |
DE4317231A1 (de) * | 1993-05-24 | 1994-12-01 | Wolff Walsrode Ag | Thermoplastische Celluloseetherester-Mischpfropfpolymerisate und Verfahren zu ihrer Herstellung |
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-
1996
- 1996-04-12 WO PCT/JP1996/001020 patent/WO1996032434A1/ja not_active Application Discontinuation
- 1996-04-12 AT AT96909364T patent/ATE226966T1/de not_active IP Right Cessation
- 1996-04-12 DK DK96909364T patent/DK0852243T3/da active
- 1996-04-12 HU HU9801120A patent/HU221090B1/hu not_active IP Right Cessation
- 1996-04-12 DE DE69624581T patent/DE69624581T2/de not_active Expired - Lifetime
- 1996-04-12 US US08/930,855 patent/US5973069A/en not_active Expired - Lifetime
- 1996-04-12 CN CN96194581A patent/CN1085690C/zh not_active Expired - Lifetime
- 1996-04-12 RU RU97118657/04A patent/RU2193574C2/ru not_active IP Right Cessation
- 1996-04-12 CA CA002218140A patent/CA2218140A1/en not_active Abandoned
- 1996-04-12 NZ NZ304991A patent/NZ304991A/en unknown
- 1996-04-12 PT PT96909364T patent/PT852243E/pt unknown
- 1996-04-12 AU AU52890/96A patent/AU5289096A/en not_active Abandoned
- 1996-04-12 SI SI9620064A patent/SI9620064A/sl not_active IP Right Cessation
- 1996-04-12 ES ES96909364T patent/ES2185769T3/es not_active Expired - Lifetime
- 1996-04-12 EP EP96909364A patent/EP0852243B1/de not_active Expired - Lifetime
- 1996-04-12 MX MX9707887A patent/MX9707887A/es not_active IP Right Cessation
- 1996-04-12 JP JP53089296A patent/JP4036472B2/ja not_active Expired - Lifetime
- 1996-04-12 BR BR9604895-6A patent/BR9604895A/pt not_active Application Discontinuation
- 1996-04-12 KR KR1019970707327A patent/KR19990007804A/ko not_active Application Discontinuation
-
1997
- 1997-10-13 NO NO974728A patent/NO974728L/no not_active Application Discontinuation
-
1999
- 1999-07-27 US US09/361,958 patent/US6090317A/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
CN1085690C (zh) | 2002-05-29 |
KR19990007804A (ko) | 1999-01-25 |
WO1996032434A1 (fr) | 1996-10-17 |
CA2218140A1 (en) | 1996-10-17 |
US5973069A (en) | 1999-10-26 |
DE69624581D1 (de) | 2002-12-05 |
EP0852243A4 (de) | 1998-08-26 |
HU221090B1 (en) | 2002-08-28 |
ES2185769T3 (es) | 2003-05-01 |
HUP9801120A2 (hu) | 1998-08-28 |
SI9620064A (sl) | 1998-06-30 |
PT852243E (pt) | 2003-03-31 |
DE69624581T2 (de) | 2003-05-15 |
EP0852243A1 (de) | 1998-07-08 |
HUP9801120A3 (en) | 1998-12-28 |
DK0852243T3 (da) | 2003-02-24 |
NZ304991A (en) | 2000-02-28 |
NO974728L (no) | 1997-12-05 |
CN1187212A (zh) | 1998-07-08 |
EP0852243B1 (de) | 2002-10-30 |
AU5289096A (en) | 1996-10-30 |
JP4036472B2 (ja) | 2008-01-23 |
US6090317A (en) | 2000-07-18 |
MX9707887A (es) | 1997-11-29 |
BR9604895A (pt) | 1999-11-30 |
NO974728D0 (no) | 1997-10-13 |
RU2193574C2 (ru) | 2002-11-27 |
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