DE60118367D1 - Verfahren zur fluormethylierung von alkoholen - Google Patents

Verfahren zur fluormethylierung von alkoholen

Info

Publication number
DE60118367D1
DE60118367D1 DE60118367T DE60118367T DE60118367D1 DE 60118367 D1 DE60118367 D1 DE 60118367D1 DE 60118367 T DE60118367 T DE 60118367T DE 60118367 T DE60118367 T DE 60118367T DE 60118367 D1 DE60118367 D1 DE 60118367D1
Authority
DE
Germany
Prior art keywords
fluoromethylation
alcohols
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE60118367T
Other languages
English (en)
Other versions
DE60118367T2 (de
Inventor
Christopher Bieniarz
V Ramakrishna
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott Laboratories
Original Assignee
Abbott Laboratories
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Laboratories filed Critical Abbott Laboratories
Publication of DE60118367D1 publication Critical patent/DE60118367D1/de
Application granted granted Critical
Publication of DE60118367T2 publication Critical patent/DE60118367T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C41/00—Preparation of ethers; Preparation of compounds having groups, groups or groups
    • C07C41/01—Preparation of ethers
    • C07C41/18—Preparation of ethers by reactions not forming ether-oxygen bonds
    • C07C41/28—Preparation of ethers by reactions not forming ether-oxygen bonds from acetals, e.g. by dealcoholysis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C41/00—Preparation of ethers; Preparation of compounds having groups, groups or groups
    • C07C41/48—Preparation of compounds having groups
    • C07C41/50—Preparation of compounds having groups by reactions producing groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
DE60118367T 2000-06-01 2001-05-30 Verfahren zur fluormethylierung von alkoholen Expired - Fee Related DE60118367T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US587414 1984-03-08
US09/587,414 US6245949B1 (en) 2000-06-01 2000-06-01 Synthetic method for the fluoromethylation of alcohols
PCT/US2001/017399 WO2001092192A1 (en) 2000-06-01 2001-05-30 Synthetic method for the fluoromethylation of alcohols

Publications (2)

Publication Number Publication Date
DE60118367D1 true DE60118367D1 (de) 2006-05-18
DE60118367T2 DE60118367T2 (de) 2006-12-07

Family

ID=24349705

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60118367T Expired - Fee Related DE60118367T2 (de) 2000-06-01 2001-05-30 Verfahren zur fluormethylierung von alkoholen

Country Status (28)

Country Link
US (1) US6245949B1 (de)
EP (1) EP1286940B1 (de)
JP (1) JP2003535070A (de)
KR (1) KR100849376B1 (de)
CN (1) CN1205159C (de)
AR (1) AR028936A1 (de)
AT (1) ATE321748T1 (de)
AU (2) AU6515801A (de)
BG (1) BG107334A (de)
BR (1) BR0107357A (de)
CA (1) CA2407716A1 (de)
CZ (1) CZ20023787A3 (de)
DE (1) DE60118367T2 (de)
DK (1) DK1286940T3 (de)
ES (1) ES2261417T3 (de)
HK (1) HK1054369B (de)
HU (1) HUP0302227A3 (de)
IL (2) IL152856A0 (de)
MX (1) MXPA02011853A (de)
NO (1) NO20025790L (de)
NZ (1) NZ522503A (de)
PE (1) PE20011340A1 (de)
PL (1) PL365449A1 (de)
PT (1) PT1286940E (de)
SK (1) SK17522002A3 (de)
TW (1) TWI222436B (de)
WO (1) WO2001092192A1 (de)
ZA (1) ZA200208851B (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6271422B1 (en) * 2000-06-01 2001-08-07 Abbott Laboratories Method for fluoromethylation of alcohols via halogenative decarboxylation
US8039678B2 (en) * 2006-09-29 2011-10-18 Cristalia Produtos Quimicos Farmaceuticos Ltda. Process for the preparation of chloromethyl 2,2,2-trifluoro-1-(trifluoromethyl) ethyl ether
CN101337863B (zh) * 2007-07-06 2012-04-25 江苏恒瑞医药股份有限公司 一种制备七氟烷的方法
CN101314560B (zh) * 2008-07-02 2011-06-15 鲁南制药集团股份有限公司 七氟烷的合成方法
WO2010096959A1 (zh) * 2009-02-25 2010-09-02 江苏恒瑞医药股份有限公司 制备氯甲基-1,1,1,3,3,3-六氟异丙基醚的方法
CN106117022B (zh) * 2016-08-03 2019-01-29 鲁南制药集团股份有限公司 一种回收利用七氟烷杂质f（1）的方法
CN107698430B (zh) * 2017-11-01 2021-01-08 华东医药（西安）博华制药有限公司 一种七氟烷反应液的后处理方法

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3683092A (en) * 1970-07-31 1972-08-08 Baxter Laboratories Inc Method of anesthesia
US4469898A (en) * 1979-12-26 1984-09-04 Baxter Travenol Laboratories, Inc. Method of synthesizing fluoromethylhexafluoroisopropyl ether
US4250334A (en) * 1979-12-26 1981-02-10 Baxter Travenol Laboratories, Inc. Method of synthesizing fluoromethylhexafluoroisopropyl ether
US4314087A (en) * 1979-12-26 1982-02-02 Baxter Travenol Laboratories, Inc. Methods of synthesizing hexafluoroisopropanol from impure mixtures and synthesis of a fluoromethyl ether therefrom
US4847427A (en) 1988-04-13 1989-07-11 E. I. Du Pont De Nemours And Company Process for preparing fluorocarbon polyethers
US4874901A (en) * 1988-05-06 1989-10-17 Boc, Inc. Process for the production of polyfluorinated ethers
US4996371A (en) 1990-01-16 1991-02-26 Boc, Inc. Method for fluorodecarboxylation
GB9600072D0 (en) * 1996-01-04 1996-03-06 Ici Plc Process for the production of fluoromethylhexafluoroisopropylether
WO1997030961A1 (fr) * 1996-02-21 1997-08-28 Central Glass Co., Ltd. Procede de preparation de l'ether de fluoromethyle 1,1,1,3,3,3-hexafluoro-isopropylique
US5789630A (en) 1996-02-27 1998-08-04 University Of Iowa Research Foundation Process for the synthesis of hexafluoropropanes
US5705710A (en) * 1997-01-15 1998-01-06 University Of Iowa Research Foundation Process for the synthesis of hexafluoroisopropyl ethers
US5969193A (en) * 1997-08-18 1999-10-19 Medeva Pharmaceuticals Pa, Inc. Method for the preparation of sevoflurane
US5886239A (en) * 1997-11-21 1999-03-23 Baxter International Inc. Method of preparing monofluoromethyl ethers
US6100434A (en) * 1999-03-26 2000-08-08 Abbott Laboratories Method for synthesizing sevoflurane and an intermediate thereof

Also Published As

Publication number Publication date
ES2261417T3 (es) 2006-11-16
CN1431986A (zh) 2003-07-23
BR0107357A (pt) 2004-01-06
AU2001265158B2 (en) 2006-07-20
NO20025790D0 (no) 2002-12-02
ATE321748T1 (de) 2006-04-15
PE20011340A1 (es) 2002-03-12
US6245949B1 (en) 2001-06-12
BG107334A (bg) 2003-06-30
NZ522503A (en) 2005-04-29
EP1286940A1 (de) 2003-03-05
MXPA02011853A (es) 2003-05-14
NO20025790L (no) 2002-12-02
AU6515801A (en) 2001-12-11
EP1286940B1 (de) 2006-03-29
ZA200208851B (en) 2003-11-04
CA2407716A1 (en) 2001-12-06
CN1205159C (zh) 2005-06-08
WO2001092192A1 (en) 2001-12-06
PT1286940E (pt) 2006-08-31
JP2003535070A (ja) 2003-11-25
DK1286940T3 (da) 2006-07-31
HUP0302227A3 (en) 2005-11-28
KR100849376B1 (ko) 2008-07-31
HK1054369B (zh) 2006-10-27
TWI222436B (en) 2004-10-21
DE60118367T2 (de) 2006-12-07
HUP0302227A2 (hu) 2003-10-28
PL365449A1 (en) 2005-01-10
KR20030005425A (ko) 2003-01-17
SK17522002A3 (sk) 2003-05-02
IL152856A0 (en) 2003-06-24
CZ20023787A3 (cs) 2003-04-16
HK1054369A1 (en) 2003-11-28
IL152856A (en) 2008-03-20
AR028936A1 (es) 2003-05-28

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee