DE60131397D1 - Verfahren zur gewinnung von cetamin-enantiomeren. - Google Patents

Verfahren zur gewinnung von cetamin-enantiomeren.

Info

Publication number
DE60131397D1
DE60131397D1 DE60131397T DE60131397T DE60131397D1 DE 60131397 D1 DE60131397 D1 DE 60131397D1 DE 60131397 T DE60131397 T DE 60131397T DE 60131397 T DE60131397 T DE 60131397T DE 60131397 D1 DE60131397 D1 DE 60131397D1
Authority
DE
Germany
Prior art keywords
cetamine
enantiomers
obtaining
obtaining cetamine
cetamine enantiomers
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60131397T
Other languages
English (en)
Other versions
DE60131397T2 (de
Inventor
Russo Valter Freire Torres
De Souza Russo Elisa Mannochio
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cristalia Produtos Quimicos e Farmaceuticos Ltda
Original Assignee
Cristalia Produtos Quimicos e Farmaceuticos Ltda
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cristalia Produtos Quimicos e Farmaceuticos Ltda filed Critical Cristalia Produtos Quimicos e Farmaceuticos Ltda
Publication of DE60131397D1 publication Critical patent/DE60131397D1/de
Application granted granted Critical
Publication of DE60131397T2 publication Critical patent/DE60131397T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C221/00—Preparation of compounds containing amino groups and doubly-bound oxygen atoms bound to the same carbon skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Anesthesiology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE60131397T 2000-06-19 2001-06-18 Verfahren zur gewinnung von cetamin-enantiomeren. Expired - Lifetime DE60131397T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
BR0002693 2000-06-19
BRPI0002693A BRPI0002693B8 (pt) 2000-06-19 2000-06-19 processo de obtenção dos enantiômeros da cetamina e seus sais farmaceuticamente aceitáveis
PCT/BR2001/000075 WO2001098265A2 (en) 2000-06-19 2001-06-18 Process for isolating enantiomers of racemic cetamine

Publications (2)

Publication Number Publication Date
DE60131397D1 true DE60131397D1 (de) 2007-12-27
DE60131397T2 DE60131397T2 (de) 2008-09-18

Family

ID=37515961

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60131397T Expired - Lifetime DE60131397T2 (de) 2000-06-19 2001-06-18 Verfahren zur gewinnung von cetamin-enantiomeren.

Country Status (11)

Country Link
US (1) US6743949B2 (de)
EP (1) EP1294659B1 (de)
AR (1) AR030938A1 (de)
AT (1) ATE378307T1 (de)
AU (1) AU7374401A (de)
BR (1) BRPI0002693B8 (de)
DE (1) DE60131397T2 (de)
DK (1) DK1294659T3 (de)
ES (1) ES2296757T3 (de)
PT (1) PT1294659E (de)
WO (1) WO2001098265A2 (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060063802A1 (en) 2004-03-29 2006-03-23 Matthieu Guitton Methods for the treatment of tinnitus induced by cochlear excitotoxicity
US8268866B2 (en) 2004-03-29 2012-09-18 Matthieu Guitton Methods for the treatment of tinnitus induced by cochlear excitotoxicity
US9072662B2 (en) 2004-03-29 2015-07-07 Auris Medical Ag Methods for the treatment of tinnitus induced by cochlear excitotoxicity
EP2792347A1 (de) 2005-09-28 2014-10-22 Auris Medical AG Pharmazeutische Zusammensetzungen zur Behandlung von Erkrankungen des Innenohrs
US8808263B2 (en) * 2010-01-14 2014-08-19 The Procter & Gamble Company Article of commerce including two-piece wearable absorbent article
BRPI1003620A2 (pt) 2010-09-03 2012-06-05 Ouro Fino Participacoes E Empreendimentos S A associação anestésica, composição anestésica, e, medicamento anestésico de uso veterinário
US20150044200A1 (en) 2011-12-12 2015-02-12 Otolanum Ag Treatment of tinnitus through modulation of chloride co-transporter nkcc1 in the auditory system
DK3043785T3 (da) 2013-09-13 2021-11-15 Univ Chiba Nat Univ Corp Anvendelse af r-ketamin og salt deraf som lægemidler
US20160332962A1 (en) * 2015-05-13 2016-11-17 Janssen Pharmaceutica Nv (s)-csa salt of s-ketamine, (r)-csa salt of s-ketamine and processes for the preparation of s-ketamine
JPWO2019160057A1 (ja) 2018-02-15 2021-02-04 国立大学法人千葉大学 炎症性疾患若しくは骨疾患の予防又は治療剤及び医薬組成物
CN110218157B (zh) * 2018-03-01 2022-08-23 江苏恒瑞医药股份有限公司 一种r-氯胺酮及其可药用盐的制备方法
MX2020011653A (es) 2018-05-04 2021-02-09 Perception Neuroscience Inc Métodos de tratamiento para el abuso de sustancias.

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH535201A (de) * 1969-12-19 1973-03-31 Bristol Myers Co Verfahren zur Spaltung von racemischen 2-(o-Chlorphenyl)-2-methylaminocyclohexanon in die optisch-aktiven Isomeren
EP0787116A1 (de) * 1994-10-17 1997-08-06 Akzo Nobel N.V. Verfahren zur trennung von enantiomeren aus einer racemischen mischung
DE19619665C2 (de) * 1996-05-15 2001-03-08 Goedecke Ag Racemattrennung von Ketamin

Also Published As

Publication number Publication date
EP1294659B1 (de) 2007-11-14
BR0002693A (pt) 2004-07-06
ATE378307T1 (de) 2007-11-15
AR030938A1 (es) 2003-09-03
PT1294659E (pt) 2008-02-19
EP1294659A4 (de) 2005-06-22
US6743949B2 (en) 2004-06-01
US20030212143A1 (en) 2003-11-13
EP1294659A2 (de) 2003-03-26
BRPI0002693B8 (pt) 2021-05-25
ES2296757T3 (es) 2008-05-01
BR0002693B1 (pt) 2013-12-24
WO2001098265A3 (en) 2002-08-15
WO2001098265B1 (en) 2002-10-24
DK1294659T3 (da) 2008-03-17
AU7374401A (en) 2002-01-02
DE60131397T2 (de) 2008-09-18
WO2001098265A2 (en) 2001-12-27

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Legal Events

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