BR0002693B1 - Processo de obtenção dos enantiômeros da cetamina e seus sais farmaceuticamente aceitáveis - Google Patents

Processo de obtenção dos enantiômeros da cetamina e seus sais farmaceuticamente aceitáveis

Info

Publication number
BR0002693B1
BR0002693B1 BRPI0002693-0B1A BR0002693A BR0002693B1 BR 0002693 B1 BR0002693 B1 BR 0002693B1 BR 0002693 A BR0002693 A BR 0002693A BR 0002693 B1 BR0002693 B1 BR 0002693B1
Authority
BR
Brazil
Prior art keywords
obtaining
pharmaceutically acceptable
acceptable salts
ketamine
enantiomers
Prior art date
Application number
BRPI0002693-0B1A
Other languages
English (en)
Other versions
BRPI0002693B8 (pt
BR0002693A (pt
Inventor
Russo Valter Freire Torres
De Souza Russo Elisa Mannochio
Original Assignee
Cristalia Prod Quimicos Farm
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cristalia Prod Quimicos Farm filed Critical Cristalia Prod Quimicos Farm
Priority to BRPI0002693A priority Critical patent/BRPI0002693B8/pt
Priority to PT01940028T priority patent/PT1294659E/pt
Priority to ES01940028T priority patent/ES2296757T3/es
Priority to EP01940028A priority patent/EP1294659B1/en
Priority to DK01940028T priority patent/DK1294659T3/da
Priority to PCT/BR2001/000075 priority patent/WO2001098265A2/en
Priority to DE60131397T priority patent/DE60131397T2/de
Priority to US10/297,815 priority patent/US6743949B2/en
Priority to AT01940028T priority patent/ATE378307T1/de
Priority to AU73744/01A priority patent/AU7374401A/en
Priority to ARP010102913A priority patent/AR030938A1/es
Publication of BR0002693A publication Critical patent/BR0002693A/pt
Publication of BR0002693B1 publication Critical patent/BR0002693B1/pt
Publication of BRPI0002693B8 publication Critical patent/BRPI0002693B8/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C221/00—Preparation of compounds containing amino groups and doubly-bound oxygen atoms bound to the same carbon skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00—Anaesthetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07—Optical isomers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Anesthesiology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
BRPI0002693A 2000-06-19 2000-06-19 processo de obtenção dos enantiômeros da cetamina e seus sais farmaceuticamente aceitáveis BRPI0002693B8 (pt)

Priority Applications (11)

Application Number Priority Date Filing Date Title
BRPI0002693A BRPI0002693B8 (pt) 2000-06-19 2000-06-19 processo de obtenção dos enantiômeros da cetamina e seus sais farmaceuticamente aceitáveis
PT01940028T PT1294659E (pt) 2000-06-19 2001-06-18 Processo para isolamento de enantiómeros de cetamina
ES01940028T ES2296757T3 (es) 2000-06-19 2001-06-18 Proceso para aislar los enantiomeros de la cetamina.
EP01940028A EP1294659B1 (en) 2000-06-19 2001-06-18 Process for isolating enantiomers of cetamine
DK01940028T DK1294659T3 (da) 2000-06-19 2001-06-18 Fremgangsmåde til isolering af katamin
PCT/BR2001/000075 WO2001098265A2 (en) 2000-06-19 2001-06-18 Process for isolating enantiomers of racemic cetamine
DE60131397T DE60131397T2 (de) 2000-06-19 2001-06-18 Verfahren zur gewinnung von cetamin-enantiomeren.
US10/297,815 US6743949B2 (en) 2000-06-19 2001-06-18 Process of obtainment of racemic cetamine enantiomers; process of obtainment of pharmaceutically acceptable salts from racemic cetamine enantiomes and use of pharmaceutically acceptable salts obtained by means of said mentioned process
AT01940028T ATE378307T1 (de) 2000-06-19 2001-06-18 Verfahren zur gewinnung von cetamin-enantiomeren.
AU73744/01A AU7374401A (en) 2000-06-19 2001-06-18 Process of obtainment of racemic cetamine enantiomers; process of obtainment of pharmaceutically acceptable salts from racemic cetamine enantiomers and use of pharmaceutically acceptable salts obtained by means of said mentioned process
ARP010102913A AR030938A1 (es) 2000-06-19 2001-06-19 Proceso de obtencion de los enantiomeros de la cetamina racemica; proceso de obtencion de sales farmaceuticamente aceptables de enantiomeros de la cetamina racemica y utilizacion de las sales farmaceuticamente aceptables obtenidas por el referido proceso

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
BRPI0002693A BRPI0002693B8 (pt) 2000-06-19 2000-06-19 processo de obtenção dos enantiômeros da cetamina e seus sais farmaceuticamente aceitáveis

Publications (3)

Publication Number Publication Date
BR0002693A BR0002693A (pt) 2004-07-06
BR0002693B1 true BR0002693B1 (pt) 2013-12-24
BRPI0002693B8 BRPI0002693B8 (pt) 2021-05-25

Family

ID=37515961

Family Applications (1)

Application Number Title Priority Date Filing Date
BRPI0002693A BRPI0002693B8 (pt) 2000-06-19 2000-06-19 processo de obtenção dos enantiômeros da cetamina e seus sais farmaceuticamente aceitáveis

Country Status (11)

Country Link
US (1) US6743949B2 (pt)
EP (1) EP1294659B1 (pt)
AR (1) AR030938A1 (pt)
AT (1) ATE378307T1 (pt)
AU (1) AU7374401A (pt)
BR (1) BRPI0002693B8 (pt)
DE (1) DE60131397T2 (pt)
DK (1) DK1294659T3 (pt)
ES (1) ES2296757T3 (pt)
PT (1) PT1294659E (pt)
WO (1) WO2001098265A2 (pt)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9072662B2 (en) 2004-03-29 2015-07-07 Auris Medical Ag Methods for the treatment of tinnitus induced by cochlear excitotoxicity
US8268866B2 (en) 2004-03-29 2012-09-18 Matthieu Guitton Methods for the treatment of tinnitus induced by cochlear excitotoxicity
US20060063802A1 (en) 2004-03-29 2006-03-23 Matthieu Guitton Methods for the treatment of tinnitus induced by cochlear excitotoxicity
EA017264B1 (ru) 2005-09-28 2012-11-30 Аурис Медикаль Аг Применение композиции арилциклоалкиламида для получения лекарственного препарата для лечения нарушения внутреннего уха
US8808263B2 (en) * 2010-01-14 2014-08-19 The Procter & Gamble Company Article of commerce including two-piece wearable absorbent article
BRPI1003620A2 (pt) 2010-09-03 2012-06-05 Ouro Fino Participacoes E Empreendimentos S A associação anestésica, composição anestésica, e, medicamento anestésico de uso veterinário
ES2862673T3 (es) 2011-12-12 2021-10-07 Zilentin AG Tratamiento del tinnitus mediante la modulación del cotransportador de cloruro NKCC1 en el sistema auditivo
EP3043785B1 (en) 2013-09-13 2021-08-25 National University Corporation Chiba University Application of r-ketamine and salt thereof as pharmaceuticals
US20160332962A1 (en) * 2015-05-13 2016-11-17 Janssen Pharmaceutica Nv (s)-csa salt of s-ketamine, (r)-csa salt of s-ketamine and processes for the preparation of s-ketamine
CN110218157B (zh) * 2018-03-01 2022-08-23 江苏恒瑞医药股份有限公司 一种r-氯胺酮及其可药用盐的制备方法
AU2019262197A1 (en) 2018-05-04 2020-11-26 Perception Neuroscience, Inc. Methods of treating substance abuse

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH535201A (de) * 1969-12-19 1973-03-31 Bristol Myers Co Verfahren zur Spaltung von racemischen 2-(o-Chlorphenyl)-2-methylaminocyclohexanon in die optisch-aktiven Isomeren
JPH10507192A (ja) * 1994-10-17 1998-07-14 アクゾ ノーベル ナムローゼ フェンノートシャップ ラセミ混合物から鏡像異性体を分離する方法
DE19619665C2 (de) * 1996-05-15 2001-03-08 Goedecke Ag Racemattrennung von Ketamin

Also Published As

Publication number Publication date
WO2001098265A2 (en) 2001-12-27
EP1294659A2 (en) 2003-03-26
DE60131397D1 (de) 2007-12-27
DE60131397T2 (de) 2008-09-18
EP1294659B1 (en) 2007-11-14
WO2001098265B1 (en) 2002-10-24
PT1294659E (pt) 2008-02-19
ES2296757T3 (es) 2008-05-01
US6743949B2 (en) 2004-06-01
AU7374401A (en) 2002-01-02
EP1294659A4 (en) 2005-06-22
US20030212143A1 (en) 2003-11-13
WO2001098265A3 (en) 2002-08-15
AR030938A1 (es) 2003-09-03
BRPI0002693B8 (pt) 2021-05-25
BR0002693A (pt) 2004-07-06
DK1294659T3 (da) 2008-03-17
ATE378307T1 (de) 2007-11-15

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Legal Events

Date Code Title Description
GLA Others concerning applications: notification of judicial decision
FBOS Technical and formal requirements: other requirements
B06A Patent application procedure suspended [chapter 6.1 patent gazette]
B07A Application suspended after technical examination (opinion) [chapter 7.1 patent gazette]
B07D Technical examination (opinion) related to article 229 of industrial property law [chapter 7.4 patent gazette]
B07E Notification of approval relating to section 229 industrial property law [chapter 7.5 patent gazette]

Free format text: NOTIFICACAO DE ANUENCIA RELACIONADA COM O ART 229 DA LPI

B09A Decision: intention to grant [chapter 9.1 patent gazette]
B16A Patent or certificate of addition of invention granted [chapter 16.1 patent gazette]

Free format text: PRAZO DE VALIDADE: 10 (DEZ) ANOS CONTADOS A PARTIR DE 24/12/2013, OBSERVADAS AS CONDICOES LEGAIS.

B16C Correction of notification of the grant [chapter 16.3 patent gazette]

Free format text: PRAZO DE VALIDADE: 20 (VINTE) ANOS CONTADOS A PARTIR DE 19/06/2000 OBSERVADAS AS CONDICOES LEGAIS. PATENTE CONCEDIDA CONFORME ADI 5.529/DF

B21A Patent or certificate of addition expired [chapter 21.1 patent gazette]

Free format text: PATENTE EXTINTA EM 19/06/2020