DE60036930D1 - Humanes cytokin als ligand des zalpha rezeptors und dessen verwendungen - Google Patents

Humanes cytokin als ligand des zalpha rezeptors und dessen verwendungen

Info

Publication number
DE60036930D1
DE60036930D1 DE60036930T DE60036930T DE60036930D1 DE 60036930 D1 DE60036930 D1 DE 60036930D1 DE 60036930 T DE60036930 T DE 60036930T DE 60036930 T DE60036930 T DE 60036930T DE 60036930 D1 DE60036930 D1 DE 60036930D1
Authority
DE
Germany
Prior art keywords
humanese
cytokin
ligand
polypeptide
zalpha
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60036930T
Other languages
English (en)
Other versions
DE60036930T2 (de
Inventor
Julie E Novak
Scott R Presnell
Cindy A Sprecher
Donald C Foster
Richard D Holly
Jane A Gross
Janet V Johnston
Andrew J Nelson
Stacey R Dillon
Angela K Hammond
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Zymogenetics Inc
Original Assignee
Zymogenetics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27385745&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE60036930(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Zymogenetics Inc filed Critical Zymogenetics Inc
Publication of DE60036930D1 publication Critical patent/DE60036930D1/de
Application granted granted Critical
Publication of DE60036930T2 publication Critical patent/DE60036930T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/55—Fusion polypeptide containing a fusion with a toxin, e.g. diphteria toxin

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • External Artificial Organs (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
DE60036930T 1999-03-09 2000-03-09 Humanes cytokin als ligand des zalpha rezeptors und dessen verwendungen Expired - Lifetime DE60036930T2 (de)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US26490899A 1999-03-09 1999-03-09
US264908 1999-03-09
US26599299A 1999-03-11 1999-03-11
US265992 1999-03-11
US14201399P 1999-07-01 1999-07-01
US142013P 1999-07-01
PCT/US2000/006067 WO2000053761A2 (en) 1999-03-09 2000-03-09 Human cytokine as ligand of the zalpha receptor and uses thereof

Publications (2)

Publication Number Publication Date
DE60036930D1 true DE60036930D1 (de) 2007-12-13
DE60036930T2 DE60036930T2 (de) 2008-10-09

Family

ID=27385745

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60036930T Expired - Lifetime DE60036930T2 (de) 1999-03-09 2000-03-09 Humanes cytokin als ligand des zalpha rezeptors und dessen verwendungen

Country Status (23)

Country Link
EP (3) EP1881070B1 (de)
JP (1) JP4405686B2 (de)
KR (1) KR100743640B1 (de)
CN (5) CN1927883B (de)
AT (1) ATE377076T1 (de)
AU (2) AU777842B2 (de)
BR (1) BR0008772B1 (de)
CA (1) CA2366921C (de)
CZ (1) CZ302921B6 (de)
DE (1) DE60036930T2 (de)
DK (1) DK1165791T3 (de)
ES (1) ES2295019T3 (de)
HU (1) HU229148B1 (de)
IL (5) IL145288A0 (de)
MX (1) MXPA01009074A (de)
NO (2) NO331551B1 (de)
NZ (1) NZ514708A (de)
PL (1) PL207350B1 (de)
PT (1) PT1165791E (de)
RU (1) RU2346951C2 (de)
UA (1) UA84387C2 (de)
WO (1) WO2000053761A2 (de)
ZA (1) ZA017370B (de)

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ATE377076T1 (de) * 1999-03-09 2007-11-15 Zymogenetics Inc Humanes cytokin als ligand des zalpha rezeptors und dessen verwendungen
CA2460916A1 (en) 2001-10-04 2003-04-10 Laura Carter Methods and compositions for modulating interleukin-21 receptor activity
DK1451322T3 (da) 2001-11-05 2010-02-01 Zymogenetics Inc Il-21-antagonister
EP2377549A1 (de) * 2002-06-07 2011-10-19 ZymoGenetics, Inc. Verwendung von IL-21 zur Behandlung von Virusinfektionen
EP1553982A4 (de) 2002-07-15 2008-03-26 Wyeth Corp VERFAHREN UND ZUSAMMENSETZUNGEN ZUR MODULIERUNG DER ENTWICKLUNG UND FUNKTION VON T-HELFER-ZELLEN (T sb H /sb )
US20060177421A1 (en) * 2002-10-11 2006-08-10 Novo Nordisk A/S Treatment of allergic conditions by use of il 21
PL376118A1 (en) * 2002-10-11 2005-12-12 Novo Nordisk A/S Treatment of allergic conditions by use of il 21
DE60330044D1 (de) * 2002-12-13 2009-12-24 Zymogenetics Inc Il-21-produktion in prokaryontischen wirten
MXPA05009556A (es) 2003-03-14 2005-11-16 Wyeth Corp Anticuerpos contra receptor de il-21 humano y sus usos.
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EP1673387B1 (de) * 2003-10-10 2010-09-15 Novo Nordisk A/S Il-21-derivate
US20060228331A1 (en) * 2003-10-10 2006-10-12 Novo Nordisk A/S IL-21 Derivatives and variants
EP2641611A3 (de) 2003-10-17 2013-12-18 Novo Nordisk A/S Kombinationstherapie
WO2005067956A2 (en) * 2004-01-15 2005-07-28 Novo Nordisk A/S Use of interleukin-21 for the treatment of autoimune diseases and allograft rejection
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DE602006020032D1 (de) 2005-04-18 2011-03-24 Novo Nordisk As Il-21-varianten
AU2006340750B2 (en) 2005-11-28 2013-03-07 Zymogenetics, Inc. IL-21 antagonists
CA2666426A1 (en) 2006-10-26 2008-05-02 Novo Nordisk A/S Il-21 variants
EP2109620B1 (de) 2006-12-21 2012-08-22 Novo Nordisk A/S Interleukin-21-varianten mit geänderter bindung an den il-21-rezeptor
WO2010055366A2 (en) 2007-12-07 2010-05-20 Zymogenetics, Inc. Anti-human il-21 monoclonal antibodies
AR071885A1 (es) 2008-05-23 2010-07-21 Wyeth Corp Proteinas de union al receptor de interleuquina 21
AR072136A1 (es) 2008-05-23 2010-08-11 Wyeth Corp Metodos de tratamiento que utilizan proteinas de union del receptor de in-terleuquina 21
JP2012504939A (ja) 2008-09-23 2012-03-01 ワイス・エルエルシー 架橋結合タンパク質による活性化シグナルの産生を予測するための方法
CN102021196B (zh) * 2009-11-20 2013-06-26 上海杰隆生物工程股份有限公司 毕赤酵母生产重组人白细胞介素21的方法
IN2015KN00073A (de) 2012-06-27 2015-07-31 Univ Rutgers
WO2015110930A1 (en) 2014-01-24 2015-07-30 Pfizer Inc. Modified interleukin 21 receptor proteins
EP2982693A1 (de) * 2014-08-07 2016-02-10 Affimed Therapeutics AG CD3 Bindungsdomäne
US12012441B2 (en) 2020-10-26 2024-06-18 Neptune Biosciences Llc Engineered human IL-21 cytokines and methods for using the same
CN112662694A (zh) * 2020-12-25 2021-04-16 康九生物科技(长春)有限公司 一种麦芽糖结合蛋白、麦芽糖结合蛋白表达载体、重组工程菌及其应用

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Also Published As

Publication number Publication date
AU3731200A (en) 2000-09-28
CZ302921B6 (cs) 2012-01-18
BR0008772B1 (pt) 2011-11-01
BR0008772A (pt) 2002-05-07
RU2004126135A (ru) 2006-02-10
EP1165791B1 (de) 2007-10-31
EP1881070A2 (de) 2008-01-23
JP2002537839A (ja) 2002-11-12
PL207350B1 (pl) 2010-12-31
NO20111085L (no) 2001-11-09
EP2295577A2 (de) 2011-03-16
AU777842B2 (en) 2004-11-04
DK1165791T3 (da) 2008-02-11
MXPA01009074A (es) 2002-03-27
EP1881070B1 (de) 2012-10-03
EP1881070A3 (de) 2008-03-05
CN1927883B (zh) 2011-09-21
EP1165791A2 (de) 2002-01-02
AU2005200240A1 (en) 2005-02-17
WO2000053761A3 (en) 2000-12-21
CN1827639A (zh) 2006-09-06
HUP0200418A2 (hu) 2002-05-29
IL195713A (en) 2010-11-30
CN100500846C (zh) 2009-06-17
CA2366921A1 (en) 2000-09-14
CA2366921C (en) 2013-12-17
KR20010103794A (ko) 2001-11-23
DE60036930T2 (de) 2008-10-09
CN101575377B (zh) 2012-12-26
CZ20013184A3 (cs) 2002-04-17
CN102406937A (zh) 2012-04-11
ZA017370B (en) 2002-06-26
HUP0200418A3 (en) 2003-12-29
EP2295577A3 (de) 2012-08-08
JP4405686B2 (ja) 2010-01-27
CN101575377A (zh) 2009-11-11
RU2346951C2 (ru) 2009-02-20
IL145288A (en) 2010-11-30
ATE377076T1 (de) 2007-11-15
WO2000053761A2 (en) 2000-09-14
PT1165791E (pt) 2008-01-16
NO20014364D0 (no) 2001-09-07
KR100743640B1 (ko) 2007-07-27
IL207403A (en) 2012-03-29
IL145288A0 (en) 2002-06-30
NO20014364L (no) 2001-11-09
ES2295019T3 (es) 2008-04-16
UA84387C2 (ru) 2008-10-27
NO331551B1 (no) 2012-01-23
HU229148B1 (en) 2013-09-30
CN1927883A (zh) 2007-03-14
CN1378595A (zh) 2002-11-06
PL351160A1 (en) 2003-03-24
NZ514708A (en) 2005-01-28
IL207424A (en) 2013-04-30

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