ATE54167T1 - Promotoren fuer die expression von fremden genen in hefe, plasmide, die diese promotoren enthalten, sowie deren verwendung zur herstellung von polypeptiden. - Google Patents
Promotoren fuer die expression von fremden genen in hefe, plasmide, die diese promotoren enthalten, sowie deren verwendung zur herstellung von polypeptiden.Info
- Publication number
- ATE54167T1 ATE54167T1 AT85870171T AT85870171T ATE54167T1 AT E54167 T1 ATE54167 T1 AT E54167T1 AT 85870171 T AT85870171 T AT 85870171T AT 85870171 T AT85870171 T AT 85870171T AT E54167 T1 ATE54167 T1 AT E54167T1
- Authority
- AT
- Austria
- Prior art keywords
- promoters
- yeast
- expression
- plasmids containing
- foreign genes
- Prior art date
Links
- 240000004808 Saccharomyces cerevisiae Species 0.000 title abstract 3
- 239000013612 plasmid Substances 0.000 title abstract 3
- 229920001184 polypeptide Polymers 0.000 title abstract 3
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 3
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 3
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- 108090000623 proteins and genes Proteins 0.000 title abstract 2
- 239000012634 fragment Substances 0.000 abstract 2
- 239000002773 nucleotide Substances 0.000 abstract 1
- 125000003729 nucleotide group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
- C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
- C12N9/2405—Glucanases
- C12N9/2408—Glucanases acting on alpha -1,4-glucosidic bonds
- C12N9/2411—Amylases
- C12N9/2414—Alpha-amylase (3.2.1.1.)
- C12N9/2417—Alpha-amylase (3.2.1.1.) from microbiological source
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
- C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
- C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
- C12N9/2462—Lysozyme (3.2.1.17)
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- Mycology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| BE0/214123A BE901222A (fr) | 1984-12-06 | 1984-12-06 | Promoteurs assurant l'expression de genes etrangers chez la levure, plasmides comportant ces promoteurs et leurs utilisations pour la production de polypeptides. |
| EP85870171A EP0184576B1 (de) | 1984-12-06 | 1985-12-05 | Promotoren für die Expression von fremden Genen in Hefe, Plasmide, die diese Promotoren enthalten, sowie deren Verwendung zur Herstellung von Polypeptiden |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE54167T1 true ATE54167T1 (de) | 1990-07-15 |
Family
ID=3843826
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT85870171T ATE54167T1 (de) | 1984-12-06 | 1985-12-05 | Promotoren fuer die expression von fremden genen in hefe, plasmide, die diese promotoren enthalten, sowie deren verwendung zur herstellung von polypeptiden. |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US4990446A (de) |
| EP (1) | EP0184576B1 (de) |
| JP (1) | JPH06104065B2 (de) |
| AT (1) | ATE54167T1 (de) |
| CA (1) | CA1280080C (de) |
| DE (1) | DE3578435D1 (de) |
Families Citing this family (51)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH04502260A (ja) * | 1989-10-16 | 1992-04-23 | アムジエン・インコーポレーテツド | Ｎ―アセチルムラミダーゼ ｍ１ |
| PT931148E (pt) | 1996-10-16 | 2006-06-30 | Zymogenetics Inc | Homologos do factor de crescimento fibroblastico |
| JP4704565B2 (ja) | 1998-09-23 | 2011-06-15 | ザイモジェネティクス， インコーポレイテッド | サイトカインレセプターｚａｌｐｈａ１１ |
| WO2000034474A2 (en) | 1998-12-07 | 2000-06-15 | Zymogenetics, Inc. | Growth factor homolog zvegf3 |
| EP1354598A3 (de) | 1999-01-07 | 2003-11-19 | ZymoGenetics, Inc. | Verfahren zur therapeutischen Verwendung von löslichen rezeptoren BR43X2 |
| US7833529B1 (en) | 1999-01-07 | 2010-11-16 | Zymogenetics, Inc. | Methods for inhibiting B lymphocyte proliferation with soluble ztnf4 receptor |
| MXPA01009074A (es) | 1999-03-09 | 2002-03-27 | Zymogenetics Inc | Nuevo ligando zalfa11 de citocina. |
| CA2378519C (en) | 1999-07-07 | 2011-01-25 | Zymogenetics, Inc. | Human cytokine receptor |
| EP2194130A1 (de) | 1999-12-23 | 2010-06-09 | ZymoGenetics, L.L.C. | Zytokin ZCYT018 |
| DE60142511D1 (de) | 2000-05-11 | 2010-08-19 | Zymogenetics Inc | Zsig33-ähnliche peptide |
| JP2004501628A (ja) | 2000-06-26 | 2004-01-22 | ザイモジェネティクス，インコーポレイティド | サイトカイン受容体ｚｃｙｔｏｒ１７ |
| DK1717316T3 (da) | 2000-06-30 | 2008-12-08 | Zymogenetics Inc | Allelisk variant af interferon-lignende protein Zcyto21 |
| US7009045B2 (en) * | 2000-07-14 | 2006-03-07 | Archer-Daniels-Midland Company | Transformation systems for flavinogenic yeast |
| EP1736545A3 (de) | 2000-08-08 | 2007-03-28 | ZymoGenetics, Inc. | Lösliche Zcyctor 11 Cytokinrezeptoren |
| US20030012783A1 (en) | 2001-02-20 | 2003-01-16 | Wayne Kindsvogel | Antibodies that bind both BCMA and TACI |
| ATE446771T1 (de) | 2001-05-24 | 2009-11-15 | Zymogenetics Inc | Taci-immunoglobulin-fusionsproteine |
| AU2002336676A1 (en) | 2001-11-05 | 2003-05-19 | Zymogenetics, Inc | Il-21 antagonists |
| ATE547430T1 (de) | 2002-01-18 | 2012-03-15 | Zymogenetics Inc | Multimere des cytokinrezeptors zcytor17 |
| ES2377188T3 (es) | 2002-01-18 | 2012-03-23 | Zymogenetics, Inc. | Nuevo ligando de citocina ZCYTOR17 |
| EP1497415B1 (de) | 2002-04-19 | 2010-12-29 | ZymoGenetics, L.L.C. | Verfahren zum nachweis oder zur modulierung der wechselwirkung eines cytokinrezeptors mit seinem ligand |
| ES2303132T3 (es) | 2003-08-07 | 2008-08-01 | Zymogenetics, Inc. | Preparaciones homogeneas de il-29. |
| US7381794B2 (en) | 2004-03-08 | 2008-06-03 | Zymogenetics, Inc. | Dimeric fusion proteins and materials and methods for producing them |
| CN101829318B (zh) | 2004-07-29 | 2012-07-04 | 津莫吉尼蒂克斯有限责任公司 | Il-28和il-29治疗癌症和自身免疫性疾病的用途 |
| EP2166103B1 (de) | 2004-08-02 | 2013-05-22 | BASF Plant Science GmbH | Verfahren zur Isolierung von Transkriptionsabschlusssequenzen |
| EP1856156A2 (de) | 2005-02-08 | 2007-11-21 | ZymoGenetics, Inc. | Anti-il-20-, anti-il-22- und anti-il-22ra-antikörper und bindungspartner sowie verwendungsverfahren bei entzündungen |
| ATE515512T1 (de) | 2005-05-12 | 2011-07-15 | Zymogenetics Inc | Zusammensetzungen und verfahren zur modulierung von immunreaktionen |
| UA93516C2 (ru) * | 2005-08-09 | 2011-02-25 | Займоджинетикс, Инк. | Способы лечения b-клеточных злокачественных образований c помощью слитой молекулы taci-ig |
| AR059025A1 (es) | 2005-08-09 | 2008-03-12 | Zymogenetics Inc | Metodos para el tratamiento y prevencion de proliferacion de celulas anormales utilizando moleculas de fusion taci |
| AR060935A1 (es) * | 2006-05-15 | 2008-07-23 | Ares Trading Sa | Metodos para tratar enfermedades autoinmunes utilizando una molecula de fusion taci- ig |
| WO2008157263A2 (en) | 2007-06-15 | 2008-12-24 | Arkansas State University | Methods of delivery of molecules to cells using a ricin subunit and compositions relating to same |
| WO2009065415A1 (en) | 2007-11-21 | 2009-05-28 | Roskilde Universitet | Polypeptides comprising an ice-binding activity |
| CN101952309A (zh) * | 2007-12-21 | 2011-01-19 | Ifxa有限公司 | 蛋白酶抑制剂 |
| WO2009092806A2 (en) * | 2008-01-25 | 2009-07-30 | Aarhus Universitet | Selective exosite inhibition of papp-a activity against igfbp-4 |
| AU2009228158B2 (en) | 2008-03-27 | 2014-02-27 | Zymogenetics, Inc. | Compositions and methods for inhibiting PDGFRbeta and VEGF-A |
| CN102131517B (zh) | 2008-06-27 | 2014-12-17 | 津莫吉尼蒂克斯公司 | 可溶性杂合Fc γ受体和相关的方法 |
| CN103168048B (zh) | 2010-06-09 | 2017-02-15 | 酶原遗传学有限公司 | 二聚vstm3融合蛋白和相关的组合物和方法 |
| US9771576B2 (en) | 2012-02-01 | 2017-09-26 | Synthetic Genomics, Inc. | Materials and methods for the synthesis of error-minimized nucleic acid molecules |
| WO2014202089A2 (en) | 2013-06-18 | 2014-12-24 | Roskilde Universitet | Variants of anti-freeze polypeptides |
| AU2016321146C1 (en) | 2015-09-08 | 2021-10-28 | Theripion, Inc. | ApoA-1 fusion polypeptides and related compositions and methods |
| CN108367004B (zh) | 2015-09-21 | 2022-09-13 | 阿帕特夫研究和发展有限公司 | Cd3结合多肽 |
| WO2018136163A2 (en) | 2016-12-09 | 2018-07-26 | Theripion, Inc. | Tandem apoa-1 fusion polypeptides |
| JP7369113B2 (ja) | 2017-07-20 | 2023-10-25 | アプティーボ リサーチ アンド デベロップメント エルエルシー | 癌胎児性抗原結合タンパク質、関連する化合物および方法 |
| ES2965187T3 (es) | 2017-12-20 | 2024-04-11 | Harbour Biomed Shanghai Co Ltd | Anticuerpos que unen CTLA-4 y sus usos |
| ES3039238T3 (en) | 2017-12-27 | 2025-10-20 | Imunami Laboratories Pte Ltd | Recombinant polypeptides and methods of use thereof |
| US10150801B1 (en) | 2017-12-27 | 2018-12-11 | Imunami Laboratories Pte. Ltd. | Recombinant polypeptides and methods of use thereof |
| US10675332B1 (en) | 2019-08-26 | 2020-06-09 | Imunami Laboratories Pte. Ltd. | Recombinant polypeptides and methods of use thereof |
| EP4021512A1 (de) | 2019-08-26 | 2022-07-06 | Imunami Laboratories Pte. Ltd. | Rekombinante polypeptide und verfahren zur verwendung davon |
| EP4168034B1 (de) | 2020-06-22 | 2025-11-26 | Imunami Laboratories Pte. Ltd. | Rekombinantes alpha-a-crystallin und kombinationen zur verwendung bei der behandlung von krebs |
| EP4294827A1 (de) | 2021-02-19 | 2023-12-27 | Theripion, Inc. | Paraoxonasefusionspolypeptide sowie zugehörige zusammensetzungen und verfahren |
| WO2024148328A2 (en) | 2023-01-06 | 2024-07-11 | Aptevo Research And Development Llc | Bispecific pd-l1 and cd40 binding molecules and uses thereof |
| WO2024259220A1 (en) | 2023-06-15 | 2024-12-19 | Theripion, Inc. | Pon3 and evolved pon1 fusion polypeptides |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2441659A1 (fr) * | 1978-11-14 | 1980-06-13 | Anvar | Nouveaux plasmides hybrides et microorganismes les contenant |
| US4615974A (en) * | 1981-08-25 | 1986-10-07 | Celltech Limited | Yeast expression vectors |
| JPS5974988A (ja) * | 1982-10-20 | 1984-04-27 | Suntory Ltd | 酵母の誘導発現型プラスミドベクタ−およびその利用方法 |
| US4661454A (en) * | 1983-02-28 | 1987-04-28 | Collaborative Research, Inc. | GAL1 yeast promoter linked to non galactokinase gene |
| NZ207925A (en) * | 1983-04-25 | 1988-05-30 | Genentech Inc | Yeast expression vehicle consisting of a yeast promoter and signal peptide encoding region linked to a heterologus peptide coding region; expression and culture |
-
1985
- 1985-12-05 EP EP85870171A patent/EP0184576B1/de not_active Expired - Lifetime
- 1985-12-05 CA CA000496939A patent/CA1280080C/en not_active Expired - Lifetime
- 1985-12-05 AT AT85870171T patent/ATE54167T1/de not_active IP Right Cessation
- 1985-12-05 US US06/804,928 patent/US4990446A/en not_active Expired - Lifetime
- 1985-12-05 DE DE8585870171T patent/DE3578435D1/de not_active Expired - Lifetime
- 1985-12-06 JP JP60273531A patent/JPH06104065B2/ja not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| JPS61185190A (ja) | 1986-08-18 |
| DE3578435D1 (de) | 1990-08-02 |
| JPH06104065B2 (ja) | 1994-12-21 |
| EP0184576A1 (de) | 1986-06-11 |
| US4990446A (en) | 1991-02-05 |
| CA1280080C (en) | 1991-02-12 |
| EP0184576B1 (de) | 1990-06-27 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ATE54167T1 (de) | Promotoren fuer die expression von fremden genen in hefe, plasmide, die diese promotoren enthalten, sowie deren verwendung zur herstellung von polypeptiden. | |
| ATE77104T1 (de) | Menge und verfahren zur herstellung rekombinierter erzeugnisse in grosser ausbeute. | |
| ES8609458A1 (es) | Un procedimiento para preparar polipeptidos | |
| FR2681786B1 (de) | ||
| FI854145A0 (fi) | Pichia-sukuisten hiivojen transformointi | |
| GB2137208B (en) | The use of the gal1 promoter | |
| ATE138975T1 (de) | Expressionssysteme für hefe mit vektoren, die einen gapdh-promotor enthalten und oberflächenantigensynthese von hepatitis b | |
| HK49285A (en) | Interferons and process for their preparation | |
| ATE43636T1 (de) | Hefe-hybridvektoren und ihre verwendung fuer die herstellung von polypeptiden. | |
| MX26714A (es) | Procedimiento para la preparacion de albumina de SUERO HUMANO VECTOR Y PLASMIDO USADOS ASI COMO LEVADURA METILOTROFICA TRANSFORMADA OBTENIDA | |
| NZ211827A (en) | Production of polypeptides having interferon activity, polypeptide compositions and dna | |
| DE3175357D1 (en) | Dna sequences encoding various allelic forms of mature thaumatin, recombinant plasmids comprising said dna's and a process for their preparation, bacterial cultures comprising said recombinant plasmids, and method for producing mature thaumatin | |
| DE151475T1 (de) | Adult-t-zell-leukemiavirus-antigenpolypeptid. | |
| IE801912L (en) | Gaming machine | |
| ATE88754T1 (de) | Transformierte hefen die lysozym produzieren, fuer diese transformation zu verwendende plasmide und deren verwendung. | |
| EP0072541A3 (de) | Menschliche Leukozyten-Interferone, Verfahren zu deren Mikrobiologischer Herstellung, Zwischenprodukte und diese enthaltende Zusammensetzungen | |
| ATE233321T1 (de) | Verbesserungen in der herstellung von proteinen in wirtszellen | |
| ATE43139T1 (de) | Klonierungs- und expressionsvektoren fuer gammainterferon, transformierte bakterien und verfahren zur herstellung von gamma-interferon. | |
| ATE139568T1 (de) | Achromobacter-protease-i-gen sowie genprodukt | |
| DE69031996D1 (de) | Menschlicher rekombinanter plazentaler ribonuklease-inhibitor und verfahren zur herstellung | |
| DE3576081D1 (de) | Spezifisches polypeptid produzierende hybridzellinien, erhaeltlich aus primaerzellen, die spontan faehig sind zur expres sion dieses polypeptids oder eines aehnlichen polypeptids, verfahren zum erhalten dieser hybridzellen und deren verwendung zur herstellung dieses polypeptids. | |
| DE3688549D1 (de) | Verfahren zur expression von genen in hefe, dns-fragmente und plasmide die letztere fragmente enthalten und zur durchfuehrung des verfahrens verwendet werden. | |
| ATE107358T1 (de) | System der induzierbaren positiven regulation zur verwendung für die herstellung von heterologen proteinen. |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| EELA | Cancelled due to lapse of time |