ATE54167T1 - Promotoren fuer die expression von fremden genen in hefe, plasmide, die diese promotoren enthalten, sowie deren verwendung zur herstellung von polypeptiden. - Google Patents

Promotoren fuer die expression von fremden genen in hefe, plasmide, die diese promotoren enthalten, sowie deren verwendung zur herstellung von polypeptiden.

Info

Publication number
ATE54167T1
ATE54167T1 AT85870171T AT85870171T ATE54167T1 AT E54167 T1 ATE54167 T1 AT E54167T1 AT 85870171 T AT85870171 T AT 85870171T AT 85870171 T AT85870171 T AT 85870171T AT E54167 T1 ATE54167 T1 AT E54167T1
Authority
AT
Austria
Prior art keywords
promoters
yeast
expression
plasmids containing
foreign genes
Prior art date
Application number
AT85870171T
Other languages
English (en)
Inventor
Jacques Oberto
John R N Davison
Original Assignee
Fina Research
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from BE0/214123A external-priority patent/BE901222A/fr
Application filed by Fina Research filed Critical Fina Research
Application granted granted Critical
Publication of ATE54167T1 publication Critical patent/ATE54167T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2405—Glucanases
    • C12N9/2408—Glucanases acting on alpha -1,4-glucosidic bonds
    • C12N9/2411—Amylases
    • C12N9/2414—Alpha-amylase (3.2.1.1.)
    • C12N9/2417—Alpha-amylase (3.2.1.1.) from microbiological source
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2462—Lysozyme (3.2.1.17)

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Mycology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
AT85870171T 1984-12-06 1985-12-05 Promotoren fuer die expression von fremden genen in hefe, plasmide, die diese promotoren enthalten, sowie deren verwendung zur herstellung von polypeptiden. ATE54167T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
BE0/214123A BE901222A (fr) 1984-12-06 1984-12-06 Promoteurs assurant l'expression de genes etrangers chez la levure, plasmides comportant ces promoteurs et leurs utilisations pour la production de polypeptides.
EP85870171A EP0184576B1 (de) 1984-12-06 1985-12-05 Promotoren für die Expression von fremden Genen in Hefe, Plasmide, die diese Promotoren enthalten, sowie deren Verwendung zur Herstellung von Polypeptiden

Publications (1)

Publication Number Publication Date
ATE54167T1 true ATE54167T1 (de) 1990-07-15

Family

ID=3843826

Family Applications (1)

Application Number Title Priority Date Filing Date
AT85870171T ATE54167T1 (de) 1984-12-06 1985-12-05 Promotoren fuer die expression von fremden genen in hefe, plasmide, die diese promotoren enthalten, sowie deren verwendung zur herstellung von polypeptiden.

Country Status (6)

Country Link
US (1) US4990446A (de)
EP (1) EP0184576B1 (de)
JP (1) JPH06104065B2 (de)
AT (1) ATE54167T1 (de)
CA (1) CA1280080C (de)
DE (1) DE3578435D1 (de)

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AU772172B2 (en) 1998-09-23 2004-04-08 Zymogenetics Inc. Cytokine receptor zalpha11
CA2354325C (en) 1998-12-07 2011-08-16 Zymogenetics, Inc. Growth factor homolog zvegf3
TR200101998T2 (tr) 1999-01-07 2002-06-21 Zymogenetics, Inc. Çözünür reseptör BR 43x2 ve kullanım metodları
US7833529B1 (en) 1999-01-07 2010-11-16 Zymogenetics, Inc. Methods for inhibiting B lymphocyte proliferation with soluble ztnf4 receptor
DK1165791T3 (da) 1999-03-09 2008-02-11 Zymogenetics Inc Humant cytokin som zalpha-receptor-ligand og anvendelse deraf
DE60045931D1 (de) 1999-07-07 2011-06-16 Zymogenetics Inc Menschliches Rezeptor für Zytokine
JP2003524415A (ja) 1999-12-23 2003-08-19 ザイモジェネティクス，インコーポレイティド サイトカインｚｃｙｔｏ１８
WO2001087933A2 (en) 2000-05-11 2001-11-22 Zymogenetics, Inc. Zsig33-like peptides
WO2002000721A2 (en) 2000-06-26 2002-01-03 Zymogenetics, Inc. Cytokine receptor zcytor17
ATE360696T1 (de) 2000-06-30 2007-05-15 Zymogenetics Inc Interferon-ähnliches protein zcyto21
US7009045B2 (en) * 2000-07-14 2006-03-07 Archer-Daniels-Midland Company Transformation systems for flavinogenic yeast
EP1736545A3 (de) 2000-08-08 2007-03-28 ZymoGenetics, Inc. Lösliche Zcyctor 11 Cytokinrezeptoren
CA2438682A1 (en) 2001-02-20 2002-08-29 Zymogenetics, Inc. Antibodies that bind both bcma and taci
EA010594B1 (ru) 2001-05-24 2008-10-30 Займодженетикс, Инк. Слитые белки taci-иммуноглобулина
MXPA04004167A (es) 2001-11-05 2004-07-08 Zymogenetics Inc Antagonistas de interleucina-21.
ES2377188T3 (es) 2002-01-18 2012-03-23 Zymogenetics, Inc. Nuevo ligando de citocina ZCYTOR17
ES2382800T3 (es) 2002-01-18 2012-06-13 Zymogenetics, Inc. Multímeros Zcytor17 receptores de citocinas
EP1497415B1 (de) 2002-04-19 2010-12-29 ZymoGenetics, L.L.C. Verfahren zum nachweis oder zur modulierung der wechselwirkung eines cytokinrezeptors mit seinem ligand
PT2251353E (pt) 2003-08-07 2013-05-07 Zymogenetics Inc Preparações homogéneas de il-28 e il-29
ATE517914T1 (de) 2004-03-08 2011-08-15 Zymogenetics Inc Dimere fusionsproteine und materialien und verfahren zu deren herstellung
WO2006012644A2 (en) 2004-07-29 2006-02-02 Zymogenetics, Inc. Use of il-28 and il-29 to treat cancer
EP1781784A2 (de) 2004-08-02 2007-05-09 BASF Plant Science GmbH Verfahren zur isolierung von transkriptionsterminationssequenzen
EP2192132A3 (de) 2005-02-08 2010-08-18 ZymoGenetics, Inc. Anti-il-20-, Anti-il-22- und Anti-il-22ra-Antikörper und Bindungspartner sowie Verwendungsverfahren bei Entzündungen
JP2008544746A (ja) 2005-05-12 2008-12-11 ザイモジェネティクス， インコーポレイテッド 免疫応答を調節するための組成物および方法
WO2007019573A2 (en) 2005-08-09 2007-02-15 Zymogenetics, Inc. Methods for the treatment and prevention of abnormal cell proliferation using taci-fusion molecules
CN101262876A (zh) * 2005-08-09 2008-09-10 酶遗传学股份有限公司 用taci-ig融合分子治疗b细胞恶性肿瘤的方法
CN101489573B (zh) * 2006-05-15 2013-05-22 阿雷斯贸易股份有限公司 用TACI-Ig融合分子治疗自身免疫疾病的方法
EP2164863A4 (de) 2007-06-15 2010-07-28 Univ Arkansas Verfahren zur verabreichung von molekülen an zellen unter verwendung einer rizin-untereinheit und damit in zusammenhang stehende zusammensetzungen
EP2602263B1 (de) 2007-11-21 2019-07-17 Roskilde Universitet Polypeptide mit ice-bindender Aktivität
EP2231702A1 (de) * 2007-12-21 2010-09-29 Ifxa A/s Proteasehemmer
MX2010008083A (es) * 2008-01-25 2010-12-20 Univ Aarhus Inhibicion de exositios selectivos de actividad papp-a contra igfbp-4.
ES2456296T3 (es) 2008-03-27 2014-04-21 Zymogenetics, Inc. Composiciones y procedimientos para inhibir PDGFR beta y VEGF-A
US8658766B2 (en) 2008-06-27 2014-02-25 Zymogenetics, Inc. Soluble hybrid Fcγ receptors and related methods
US8822642B2 (en) 2010-06-09 2014-09-02 Zymogenetics, Inc. Dimeric fusion proteins and related compositions and methods
SG10201606285YA (en) 2012-02-01 2016-09-29 Synthetic Genomics Inc Materials and methods for the synthesis of error-minimized nucleic acid molecules
WO2014202089A2 (en) 2013-06-18 2014-12-24 Roskilde Universitet Variants of anti-freeze polypeptides
DK3328881T3 (da) 2015-09-08 2019-10-07 Theripion Inc Apoa-1 fusionspolypeptider og relaterede sammensætninger og fremgangsmåder
KR102784293B1 (ko) 2015-09-21 2025-03-20 압테보 리서치 앤드 디벨롭먼트 엘엘씨 Cd3 결합 폴리펩타이드
WO2018136163A2 (en) 2016-12-09 2018-07-26 Theripion, Inc. Tandem apoa-1 fusion polypeptides
IL272103B2 (en) 2017-07-20 2024-10-01 Aptevo Res & Development Llc Antigen binding proteins binding to 5T4 and 4-1BB and related compositions and methods of treating cancer
AU2018391831B2 (en) 2017-12-20 2022-08-04 Harbour Biomed (Shanghai) Co., Ltd Antibodies binding CTLA-4 and uses thereof
WO2019132765A1 (en) 2017-12-27 2019-07-04 Imunami Laboratories Pte. Ltd. Recombinant polypeptides and methods of use thereof
US10150801B1 (en) 2017-12-27 2018-12-11 Imunami Laboratories Pte. Ltd. Recombinant polypeptides and methods of use thereof
EP4021512A1 (de) 2019-08-26 2022-07-06 Imunami Laboratories Pte. Ltd. Rekombinante polypeptide und verfahren zur verwendung davon
US10675332B1 (en) 2019-08-26 2020-06-09 Imunami Laboratories Pte. Ltd. Recombinant polypeptides and methods of use thereof
EP4168034B1 (de) 2020-06-22 2025-11-26 Imunami Laboratories Pte. Ltd. Rekombinantes alpha-a-crystallin und kombinationen zur verwendung bei der behandlung von krebs
AU2022224584A1 (en) 2021-02-19 2023-09-21 Theripion, Inc. Paraoxonase fusion polypeptides and related compositions and methods
CN120584137A (zh) 2023-01-06 2025-09-02 阿帕特夫研究和发展有限公司 双特异性pd-l1和cd40结合分子以及其用途
WO2024259220A1 (en) 2023-06-15 2024-12-19 Theripion, Inc. Pon3 and evolved pon1 fusion polypeptides

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FR2441659A1 (fr) * 1978-11-14 1980-06-13 Anvar Nouveaux plasmides hybrides et microorganismes les contenant
AU560472B2 (en) * 1981-08-25 1987-04-09 Celltech Limited Yeast expression vectors
JPS5974988A (ja) * 1982-10-20 1984-04-27 Suntory Ltd 酵母の誘導発現型プラスミドベクタ−およびその利用方法
US4661454A (en) * 1983-02-28 1987-04-28 Collaborative Research, Inc. GAL1 yeast promoter linked to non galactokinase gene
NZ207925A (en) * 1983-04-25 1988-05-30 Genentech Inc Yeast expression vehicle consisting of a yeast promoter and signal peptide encoding region linked to a heterologus peptide coding region; expression and culture

Also Published As

Publication number Publication date
JPH06104065B2 (ja) 1994-12-21
US4990446A (en) 1991-02-05
EP0184576A1 (de) 1986-06-11
JPS61185190A (ja) 1986-08-18
CA1280080C (en) 1991-02-12
DE3578435D1 (de) 1990-08-02
EP0184576B1 (de) 1990-06-27

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
EELA Cancelled due to lapse of time