DE3578435D1 - Promotoren fuer die expression von fremden genen in hefe, plasmide, die diese promotoren enthalten, sowie deren verwendung zur herstellung von polypeptiden. - Google Patents

Promotoren fuer die expression von fremden genen in hefe, plasmide, die diese promotoren enthalten, sowie deren verwendung zur herstellung von polypeptiden.

Info

Publication number
DE3578435D1
DE3578435D1 DE8585870171T DE3578435T DE3578435D1 DE 3578435 D1 DE3578435 D1 DE 3578435D1 DE 8585870171 T DE8585870171 T DE 8585870171T DE 3578435 T DE3578435 T DE 3578435T DE 3578435 D1 DE3578435 D1 DE 3578435D1
Authority
DE
Germany
Prior art keywords
promotors
polypeptides
yeast
expression
plasmides
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE8585870171T
Other languages
English (en)
Inventor
Jacques Oberto
John R N Davison
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Labofina SA
Original Assignee
Labofina SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from BE0/214123A external-priority patent/BE901222A/fr
Application filed by Labofina SA filed Critical Labofina SA
Application granted granted Critical
Publication of DE3578435D1 publication Critical patent/DE3578435D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2405—Glucanases
    • C12N9/2408—Glucanases acting on alpha -1,4-glucosidic bonds
    • C12N9/2411—Amylases
    • C12N9/2414—Alpha-amylase (3.2.1.1.)
    • C12N9/2417—Alpha-amylase (3.2.1.1.) from microbiological source
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2462—Lysozyme (3.2.1.17)
DE8585870171T 1984-12-06 1985-12-05 Promotoren fuer die expression von fremden genen in hefe, plasmide, die diese promotoren enthalten, sowie deren verwendung zur herstellung von polypeptiden. Expired - Lifetime DE3578435D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
BE0/214123A BE901222A (fr) 1984-12-06 1984-12-06 Promoteurs assurant l'expression de genes etrangers chez la levure, plasmides comportant ces promoteurs et leurs utilisations pour la production de polypeptides.

Publications (1)

Publication Number Publication Date
DE3578435D1 true DE3578435D1 (de) 1990-08-02

Family

ID=3843826

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8585870171T Expired - Lifetime DE3578435D1 (de) 1984-12-06 1985-12-05 Promotoren fuer die expression von fremden genen in hefe, plasmide, die diese promotoren enthalten, sowie deren verwendung zur herstellung von polypeptiden.

Country Status (6)

Country Link
US (1) US4990446A (de)
EP (1) EP0184576B1 (de)
JP (1) JPH06104065B2 (de)
AT (1) ATE54167T1 (de)
CA (1) CA1280080C (de)
DE (1) DE3578435D1 (de)

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US5989866A (en) 1996-10-16 1999-11-23 Zymogenetics, Inc. FGF homologs
DE69941126D1 (de) 1998-09-23 2009-08-27 Zymogenetics Inc Cytokinerezeptor zalpha11
ATE404668T1 (de) 1998-12-07 2008-08-15 Zymogenetics Inc Wachstumsfaktor-homologe zvegf-3
DK1642972T3 (da) 1999-01-07 2010-05-10 Zymogenetics Inc Terapeutisk anvendelse af BR43X2 opløselige receptorer
US7833529B1 (en) 1999-01-07 2010-11-16 Zymogenetics, Inc. Methods for inhibiting B lymphocyte proliferation with soluble ztnf4 receptor
CN102406937A (zh) 1999-03-09 2012-04-11 津莫吉尼蒂克斯公司 新的细胞因子zalpha11配体
DE60045931D1 (de) 1999-07-07 2011-06-16 Zymogenetics Inc Menschliches Rezeptor für Zytokine
DE60043944D1 (de) 1999-12-23 2010-04-15 Zymogenetics Inc Zytokin zcyt018
WO2001087933A2 (en) 2000-05-11 2001-11-22 Zymogenetics, Inc. Zsig33-like peptides
AU2001273032A1 (en) 2000-06-26 2002-01-08 Zymogenetics Inc. Cytokine receptor zcytor17
ES2286128T3 (es) 2000-06-30 2007-12-01 Zymogenetics, Inc. Proteina zcyto21 tipo interferon.
US7009045B2 (en) * 2000-07-14 2006-03-07 Archer-Daniels-Midland Company Transformation systems for flavinogenic yeast
EP1736545A3 (de) 2000-08-08 2007-03-28 ZymoGenetics, Inc. Lösliche Zcyctor 11 Cytokinrezeptoren
CA2438682A1 (en) 2001-02-20 2002-08-29 Zymogenetics, Inc. Antibodies that bind both bcma and taci
CN1612750B (zh) 2001-05-24 2012-10-31 津莫吉尼蒂克斯公司 Taci-免疫球蛋白融合蛋白质
ES2334338T3 (es) 2001-11-05 2010-03-09 Zymogenetics, Inc. Antagonistas de il-21.
CA2473686C (en) 2002-01-18 2011-09-20 Zymogenetics, Inc. Novel cytokine zcytor17 ligand
ES2546797T3 (es) 2002-01-18 2015-09-28 Zymogenetics, Inc. Multímeros Zcytor17 receptores de citocinas
EP2295455A1 (de) 2002-04-19 2011-03-16 ZymoGenetics, L.L.C. Cytokinrezeptor
JP4808157B2 (ja) 2003-08-07 2011-11-02 ザイモジェネティクス リミテッド ライアビリティ カンパニー Ｉｌ−２８およびｉｌ−２９の均一な調製物
EP1732946B1 (de) 2004-03-08 2011-07-27 ZymoGenetics, Inc. Dimere fusionsproteine und materialien und verfahren zu deren herstellung
CN101829318B (zh) 2004-07-29 2012-07-04 津莫吉尼蒂克斯有限责任公司 Il-28和il-29治疗癌症和自身免疫性疾病的用途
EP1781784A2 (de) 2004-08-02 2007-05-09 BASF Plant Science GmbH Verfahren zur isolierung von transkriptionsterminationssequenzen
EP2192132A3 (de) 2005-02-08 2010-08-18 ZymoGenetics, Inc. Anti-il-20-, Anti-il-22- und Anti-il-22ra-Antikörper und Bindungspartner sowie Verwendungsverfahren bei Entzündungen
US20070054360A1 (en) 2005-05-12 2007-03-08 Zeren Gao Compositions and methods for modulating immune responses
WO2007019573A2 (en) 2005-08-09 2007-02-15 Zymogenetics, Inc. Methods for the treatment and prevention of abnormal cell proliferation using taci-fusion molecules
AR059945A1 (es) * 2005-08-09 2008-05-14 Zymogenetics Inc Metodos para tratar afecciones malignas de celulas b que utilizan una molecula de fusion taci-ig
AR060935A1 (es) * 2006-05-15 2008-07-23 Ares Trading Sa Metodos para tratar enfermedades autoinmunes utilizando una molecula de fusion taci- ig
US20100240597A1 (en) 2007-06-15 2010-09-23 Arkansas State University Methods of delivery of molecules to cells using a ricin subunit and compositions relating to same
CN101918437B (zh) 2007-11-21 2013-08-14 罗斯基勒大学 具有冰结合活性的多肽
CN101952309A (zh) * 2007-12-21 2011-01-19 Ifxa有限公司 蛋白酶抑制剂
MX2010008083A (es) * 2008-01-25 2010-12-20 Univ Aarhus Inhibicion de exositios selectivos de actividad papp-a contra igfbp-4.
CA2716882A1 (en) 2008-03-27 2009-10-01 Zymogenetics, Inc. Compositions and methods for inhibiting pdgfr-beta and vegf-a
US8658766B2 (en) 2008-06-27 2014-02-25 Zymogenetics, Inc. Soluble hybrid Fcγ receptors and related methods
US8822642B2 (en) 2010-06-09 2014-09-02 Zymogenetics, Inc. Dimeric fusion proteins and related compositions and methods
US9771576B2 (en) 2012-02-01 2017-09-26 Synthetic Genomics, Inc. Materials and methods for the synthesis of error-minimized nucleic acid molecules
WO2014202089A2 (en) 2013-06-18 2014-12-24 Roskilde Universitet Variants of anti-freeze polypeptides
JP6953020B2 (ja) 2015-09-08 2021-10-27 セリピオン， インコーポレイテッド ＡｐｏＡ−１融合ポリペプチドならびに関連する組成物および方法
WO2018136163A2 (en) 2016-12-09 2018-07-26 Theripion, Inc. Tandem apoa-1 fusion polypeptides
AU2018304585B2 (en) 2017-07-20 2023-07-06 Alligator Bioscience Ab Antigen binding proteins binding to 5T4 and 4-1BB and related compositions and methods
DK3710484T3 (da) 2017-12-20 2023-11-27 Harbour Biomed Shanghai Co Ltd Ctla-4-bindende antistoffer og anvendelser deraf
US10150801B1 (en) 2017-12-27 2018-12-11 Imunami Laboratories Pte. Ltd. Recombinant polypeptides and methods of use thereof
CA3082769A1 (en) 2017-12-27 2019-07-04 Imunami Laboratories Pte. Ltd. Recombinant polypeptides and methods of use thereof
US10675332B1 (en) 2019-08-26 2020-06-09 Imunami Laboratories Pte. Ltd. Recombinant polypeptides and methods of use thereof
WO2021040610A1 (en) 2019-08-26 2021-03-04 Imunami Laboratories Pte. Ltd. Recombinant polypeptides and methods of use thereof
CA3182917A1 (en) 2020-06-22 2021-12-30 Ya-Huei Chen Recombinant polypeptides and combinations for use in the treatment of cancer
AU2022223409A1 (en) 2021-02-19 2023-09-21 Theripion, Inc. Dnase fusion polypeptides and related compositions and methods

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Publication number Priority date Publication date Assignee Title
FR2441659A1 (fr) * 1978-11-14 1980-06-13 Anvar Nouveaux plasmides hybrides et microorganismes les contenant
IE54046B1 (en) * 1981-08-25 1989-05-24 Celltech Ltd Expression vectors
JPS5974988A (ja) * 1982-10-20 1984-04-27 Suntory Ltd 酵母の誘導発現型プラスミドベクタ−およびその利用方法
US4661454A (en) * 1983-02-28 1987-04-28 Collaborative Research, Inc. GAL1 yeast promoter linked to non galactokinase gene
NZ207925A (en) * 1983-04-25 1988-05-30 Genentech Inc Yeast expression vehicle consisting of a yeast promoter and signal peptide encoding region linked to a heterologus peptide coding region; expression and culture

Also Published As

Publication number Publication date
EP0184576B1 (de) 1990-06-27
ATE54167T1 (de) 1990-07-15
CA1280080C (en) 1991-02-12
EP0184576A1 (de) 1986-06-11
JPH06104065B2 (ja) 1994-12-21
JPS61185190A (ja) 1986-08-18
US4990446A (en) 1991-02-05

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