ATE404668T1 - Wachstumsfaktor-homologe zvegf-3 - Google Patents

Wachstumsfaktor-homologe zvegf-3

Info

Publication number
ATE404668T1
ATE404668T1 AT99966032T AT99966032T ATE404668T1 AT E404668 T1 ATE404668 T1 AT E404668T1 AT 99966032 T AT99966032 T AT 99966032T AT 99966032 T AT99966032 T AT 99966032T AT E404668 T1 ATE404668 T1 AT E404668T1
Authority
AT
Austria
Prior art keywords
zvegf
growth factor
polypeptides
seq
residues
Prior art date
Application number
AT99966032T
Other languages
English (en)
Inventor
Zeren Gao
Charles Hart
Christopher Piddington
Paul Sheppard
Kimberly Shoemaker
Debra Gilbertson
James West
Original Assignee
Zymogenetics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zymogenetics Inc filed Critical Zymogenetics Inc
Application granted granted Critical
Publication of ATE404668T1 publication Critical patent/ATE404668T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Biochemistry (AREA)
  • Vascular Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Ophthalmology & Optometry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Zoology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Cardiology (AREA)
  • Toxicology (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Urology & Nephrology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Emergency Medicine (AREA)
  • Dermatology (AREA)
  • Peptides Or Proteins (AREA)
AT99966032T 1998-12-07 1999-12-07 Wachstumsfaktor-homologe zvegf-3 ATE404668T1 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US20712098A 1998-12-07 1998-12-07
US14257699P 1999-07-06 1999-07-06
US16165399P 1999-10-21 1999-10-21
US16525599P 1999-11-12 1999-11-12

Publications (1)

Publication Number Publication Date
ATE404668T1 true ATE404668T1 (de) 2008-08-15

Family

ID=27495530

Family Applications (1)

Application Number Title Priority Date Filing Date
AT99966032T ATE404668T1 (de) 1998-12-07 1999-12-07 Wachstumsfaktor-homologe zvegf-3

Country Status (9)

Country Link
EP (2) EP1988102B1 (de)
JP (2) JP4739526B2 (de)
AT (1) ATE404668T1 (de)
AU (1) AU764039B2 (de)
CA (1) CA2354325C (de)
DE (1) DE69939330D1 (de)
DK (1) DK1137773T3 (de)
ES (2) ES2432053T3 (de)
WO (1) WO2000034474A2 (de)

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EP1064382B1 (de) 1998-03-17 2008-08-20 Genentech, Inc. Zu vegf und bmp1 homologe polypeptide
US7105481B2 (en) 1998-11-10 2006-09-12 Ludwig Institute For Cancer Research Method for stimulating connective tissue growth or wound healing
US7148037B2 (en) 1998-11-10 2006-12-12 Ludwig Institute For Cancer Research Platelet-derived growth factor D, DNA coding therefor, and uses thereof
ATE451389T1 (de) * 1998-11-10 2009-12-15 Ludwig Inst Cancer Res Von blutplättchen abstammender wachstumsfaktor d, dafür kodierende dns und deren verwendungen
KR20010103046A (ko) * 1999-03-08 2001-11-17 제넨테크, 인크. 면역 관련 질환 치료용 조성물 및 치료 방법
AU4008500A (en) * 1999-04-06 2000-10-23 Eli Lilly And Company Platelet-derived growth factor related gene and protein
US6468543B1 (en) 1999-05-03 2002-10-22 Zymogenetics, Inc. Methods for promoting growth of bone using ZVEGF4
US6630142B2 (en) 1999-05-03 2003-10-07 Zymogenetics, Inc. Method of treating fibroproliferative disorders
JP2002542825A (ja) * 1999-05-03 2002-12-17 ザイモジェネティクス，インコーポレイティド 増殖因子同族体ｚｖｅｇｆ４
CA2386383A1 (en) * 1999-10-07 2001-04-12 Curagen Corporation Growth factor polypeptides and nucleic acids encoding same
WO2001028586A1 (en) * 1999-10-21 2001-04-26 Zymogenetics, Inc. Method of treating fibrosis
US6893637B1 (en) 1999-10-21 2005-05-17 Zymogenetics, Inc. Method of treating fibrosis
AU2000251259A1 (en) * 2000-02-04 2001-08-14 Zymogenetics Inc. Methods for promoting growth of bone, ligament, and cartilage using zvegf4
JPWO2002033094A1 (ja) * 2000-10-19 2004-10-21 協和醗酵工業株式会社 Ｖｐｌｆの活性を阻害する抗体
KR20080083072A (ko) * 2001-03-09 2008-09-12 얀센 파마슈티카 엔.브이. Ｖｅｇｆ-ｘ 또는 그의 길항제에 의한 평활근 세포 증식의 조절
WO2003065043A2 (en) * 2002-01-29 2003-08-07 King's College London An Institute Incorporated By Royal Charter Of Strand Identification and relative quantification of proteins
AU2003242512A1 (en) * 2002-07-11 2004-02-02 Sema Aps Use of compounds capable of inhibiting the proteolytic processing of semaphorins for prevention, treatment, diagnosis and prognosis of an invasive disease
CA2529798C (en) * 2003-07-25 2014-09-16 Zymogenetics, Inc. Methods of treating hepatocellular carcinoma with zvegf3 antagonists
TWI376520B (en) 2004-04-30 2012-11-11 Hillcrest Lab Inc Free space pointing devices and methods
US8629836B2 (en) 2004-04-30 2014-01-14 Hillcrest Laboratories, Inc. 3D pointing devices with orientation compensation and improved usability
US8137195B2 (en) 2004-11-23 2012-03-20 Hillcrest Laboratories, Inc. Semantic gaming and application transformation
EP2841454A1 (de) 2012-04-24 2015-03-04 ThromboGenics N.V. Anti-pdgf-c-antikörper

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Also Published As

Publication number Publication date
JP5345997B2 (ja) 2013-11-20
DK1137773T3 (da) 2008-12-08
JP2011052009A (ja) 2011-03-17
EP1137773A2 (de) 2001-10-04
WO2000034474A3 (en) 2000-12-28
DE69939330D1 (de) 2008-09-25
AU764039B2 (en) 2003-08-07
ES2312223T3 (es) 2009-02-16
EP1988102B1 (de) 2013-08-21
JP2002531127A (ja) 2002-09-24
JP4739526B2 (ja) 2011-08-03
CA2354325A1 (en) 2000-06-15
EP1137773B1 (de) 2008-08-13
ES2432053T3 (es) 2013-11-29
WO2000034474A9 (en) 2002-08-29
EP1988102A1 (de) 2008-11-05
AU2167900A (en) 2000-06-26
WO2000034474A2 (en) 2000-06-15
CA2354325C (en) 2011-08-16

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