ATE404668T1 - Wachstumsfaktor-homologe zvegf-3 - Google Patents
Wachstumsfaktor-homologe zvegf-3Info
- Publication number
- ATE404668T1 ATE404668T1 AT99966032T AT99966032T ATE404668T1 AT E404668 T1 ATE404668 T1 AT E404668T1 AT 99966032 T AT99966032 T AT 99966032T AT 99966032 T AT99966032 T AT 99966032T AT E404668 T1 ATE404668 T1 AT E404668T1
- Authority
- AT
- Austria
- Prior art keywords
- zvegf
- growth factor
- polypeptides
- seq
- residues
- Prior art date
Links
- 239000003102 growth factor Substances 0.000 title abstract 2
- 229920001184 polypeptide Polymers 0.000 abstract 4
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 4
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 4
- 238000000034 method Methods 0.000 abstract 2
- 102000040430 polynucleotide Human genes 0.000 abstract 2
- 108091033319 polynucleotide Proteins 0.000 abstract 2
- 239000002157 polynucleotide Substances 0.000 abstract 2
- 150000001413 amino acids Chemical class 0.000 abstract 1
- 239000006143 cell culture medium Substances 0.000 abstract 1
- 229940039227 diagnostic agent Drugs 0.000 abstract 1
- 239000000032 diagnostic agent Substances 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 230000023252 regulation of cell development Effects 0.000 abstract 1
- 230000025366 tissue development Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Rheumatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Diabetes (AREA)
- Biochemistry (AREA)
- Vascular Medicine (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Gastroenterology & Hepatology (AREA)
- Heart & Thoracic Surgery (AREA)
- Ophthalmology & Optometry (AREA)
- Zoology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Cardiology (AREA)
- Toxicology (AREA)
- Dermatology (AREA)
- Pain & Pain Management (AREA)
- Emergency Medicine (AREA)
- Urology & Nephrology (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Endocrinology (AREA)
- Immunology (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US20712098A | 1998-12-07 | 1998-12-07 | |
| US14257699P | 1999-07-06 | 1999-07-06 | |
| US16165399P | 1999-10-21 | 1999-10-21 | |
| US16525599P | 1999-11-12 | 1999-11-12 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE404668T1 true ATE404668T1 (de) | 2008-08-15 |
Family
ID=27495530
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT99966032T ATE404668T1 (de) | 1998-12-07 | 1999-12-07 | Wachstumsfaktor-homologe zvegf-3 |
Country Status (9)
| Country | Link |
|---|---|
| EP (2) | EP1988102B1 (de) |
| JP (2) | JP4739526B2 (de) |
| AT (1) | ATE404668T1 (de) |
| AU (1) | AU764039B2 (de) |
| CA (1) | CA2354325C (de) |
| DE (1) | DE69939330D1 (de) |
| DK (1) | DK1137773T3 (de) |
| ES (2) | ES2312223T3 (de) |
| WO (1) | WO2000034474A2 (de) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2000053760A2 (en) * | 1999-03-12 | 2000-09-14 | Genentech, Inc. | Method of preventing the death of retinal neurons and treating ocular diseases |
| IL138488A0 (en) | 1998-03-17 | 2001-10-31 | Genentech Inc | Polypeptides homologous to vegf and bmp1 |
| US7148037B2 (en) | 1998-11-10 | 2006-12-12 | Ludwig Institute For Cancer Research | Platelet-derived growth factor D, DNA coding therefor, and uses thereof |
| US7105481B2 (en) | 1998-11-10 | 2006-09-12 | Ludwig Institute For Cancer Research | Method for stimulating connective tissue growth or wound healing |
| WO2000027879A1 (en) * | 1998-11-10 | 2000-05-18 | Ludwig Institute For Cancer Research | Platelet-derived growth factor d, dna coding therefor, and uses thereof |
| CA2362427A1 (en) * | 1999-03-08 | 2000-09-14 | Genentech, Inc. | Compositions and methods for the treatment of immune related diseases |
| AU4008500A (en) * | 1999-04-06 | 2000-10-23 | Eli Lilly And Company | Platelet-derived growth factor related gene and protein |
| MXPA01011158A (es) * | 1999-05-03 | 2004-06-03 | Zymogenetics Inc | Factor de crecimiento homologo zvegf4. |
| US6630142B2 (en) | 1999-05-03 | 2003-10-07 | Zymogenetics, Inc. | Method of treating fibroproliferative disorders |
| US6468543B1 (en) | 1999-05-03 | 2002-10-22 | Zymogenetics, Inc. | Methods for promoting growth of bone using ZVEGF4 |
| EP1222279A2 (de) * | 1999-10-07 | 2002-07-17 | Curagen Corporation | Wachstumsfaktorenpolypeptide und nukleinsäuren die dafür kodieren |
| WO2001028586A1 (en) * | 1999-10-21 | 2001-04-26 | Zymogenetics, Inc. | Method of treating fibrosis |
| US6893637B1 (en) | 1999-10-21 | 2005-05-17 | Zymogenetics, Inc. | Method of treating fibrosis |
| WO2001057083A1 (en) * | 2000-02-04 | 2001-08-09 | Zymogenetics, Inc. | Methods for promoting growth of bone, ligament, and cartilage using zvegf4 |
| US20040086507A1 (en) * | 2000-10-19 | 2004-05-06 | Kenya Shitara | Antibody inhibiting vplf activity |
| CN100391534C (zh) | 2001-03-09 | 2008-06-04 | 詹森药业有限公司 | 平滑肌细胞增殖的调节 |
| WO2003065043A2 (en) * | 2002-01-29 | 2003-08-07 | King's College London An Institute Incorporated By Royal Charter Of Strand | Identification and relative quantification of proteins |
| EP1534319A2 (de) * | 2002-07-11 | 2005-06-01 | Sema ApS | Verwendung von zusammensetzungen, fähig den proteolytischen prozess von seamphorinen zu hemmen, als prevention, behandlung, diagnose und prognose einer invasiven erkrankung |
| CA2529798C (en) * | 2003-07-25 | 2014-09-16 | Zymogenetics, Inc. | Methods of treating hepatocellular carcinoma with zvegf3 antagonists |
| TWI376520B (en) | 2004-04-30 | 2012-11-11 | Hillcrest Lab Inc | Free space pointing devices and methods |
| US8629836B2 (en) | 2004-04-30 | 2014-01-14 | Hillcrest Laboratories, Inc. | 3D pointing devices with orientation compensation and improved usability |
| WO2006058129A2 (en) | 2004-11-23 | 2006-06-01 | Hillcrest Laboratories, Inc. | Semantic gaming and application transformation |
| NZ700274A (en) | 2012-04-24 | 2016-10-28 | Thrombogenics Nv | Anti-pdgf-c antibodies |
Family Cites Families (63)
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|---|---|---|---|---|
| DK368882A (da) | 1981-08-25 | 1983-02-26 | Alan John Kingsman | Expessions vektorer |
| US4579821A (en) | 1981-11-23 | 1986-04-01 | University Patents, Inc. | Control of DNA sequence transcription |
| US4656134A (en) | 1982-01-11 | 1987-04-07 | Board Of Trustees Of Leland Stanford Jr. University | Gene amplification in eukaryotic cells |
| US4486533A (en) | 1982-09-02 | 1984-12-04 | St. Louis University | Filamentous fungi functional replicating extrachromosomal element |
| US4599311A (en) | 1982-08-13 | 1986-07-08 | Kawasaki Glenn H | Glycolytic promotersfor regulated protein expression: protease inhibitor |
| US4977092A (en) | 1985-06-26 | 1990-12-11 | Amgen | Expression of exogenous polypeptides and polypeptide products including hepatitis B surface antigen in yeast cells |
| US4601978A (en) | 1982-11-24 | 1986-07-22 | The Regents Of The University Of California | Mammalian metallothionein promoter system |
| US4713339A (en) | 1983-01-19 | 1987-12-15 | Genentech, Inc. | Polycistronic expression vector construction |
| US4661454A (en) | 1983-02-28 | 1987-04-28 | Collaborative Research, Inc. | GAL1 yeast promoter linked to non galactokinase gene |
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| US4766073A (en) | 1985-02-25 | 1988-08-23 | Zymogenetics Inc. | Expression of biologically active PDGF analogs in eucaryotic cells |
| CA1280080C (en) | 1984-12-06 | 1991-02-12 | Jacques Oberto | Promoters for the expression of foreign genes in yeast, plasmids comprising them, and uses thereof for the production of polypeptides |
| US4683202A (en) | 1985-03-28 | 1987-07-28 | Cetus Corporation | Process for amplifying nucleic acid sequences |
| GR860984B (en) | 1985-04-17 | 1986-08-18 | Zymogenetics Inc | Expression of factor vii and ix activities in mammalian cells |
| US4882279A (en) | 1985-10-25 | 1989-11-21 | Phillips Petroleum Company | Site selective genomic modification of yeast of the genus pichia |
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| US5124316A (en) | 1986-11-14 | 1992-06-23 | President And Fellows Of Harvard College | Method for periodontal regeneration |
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| US5124263A (en) | 1989-01-12 | 1992-06-23 | Wisconsin Alumni Research Foundation | Recombination resistant retroviral helper cell and products produced thereby |
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| US5219739A (en) | 1989-07-27 | 1993-06-15 | Scios Nova Inc. | DNA sequences encoding bVEGF120 and hVEGF121 and methods for the production of bovine and human vascular endothelial cell growth factors, bVEGF120 and hVEGF121 |
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| US5641670A (en) | 1991-11-05 | 1997-06-24 | Transkaryotic Therapies, Inc. | Protein production and protein delivery |
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| US5620687A (en) | 1993-02-25 | 1997-04-15 | Zymogenetics, Inc. | Inhibition of intimal hyperplasia using antibodies to PDGF beta receptors |
| JPH09501055A (ja) | 1993-07-30 | 1997-02-04 | ユニバーシティ オブ メディシン アンド デンティストリー オブ ニュージャージー | 初代リンパ球への効率的遺伝子転移 |
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| DE69630442T2 (de) | 1995-03-02 | 2004-08-19 | Amrad Operations Pty. Ltd., Richmond | Ein neuartiger wachstumsfaktor und eine genetische sequenz, die für diesen codiert |
| ATE290077T1 (de) | 1995-09-29 | 2005-03-15 | Univ Siena | Regulierte gene und ihre verwendungen |
| US5716808A (en) | 1995-11-09 | 1998-02-10 | Zymogenetics, Inc. | Genetic engineering of pichia methanolica |
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| US5736383A (en) | 1996-08-26 | 1998-04-07 | Zymogenetics, Inc. | Preparation of Pichia methanolica auxotrophic mutants |
| DE69734359T2 (de) * | 1996-08-23 | 2006-07-06 | Ludwig Institute For Cancer Research | Rekombinanter vaskulärer endothelzellen wachstumsfaktor d (vegf-d) |
| AU5439998A (en) * | 1996-12-06 | 1998-06-29 | Zymogenetics Inc. | Vascular endothelial growth factor |
| WO1999037671A1 (en) * | 1998-01-27 | 1999-07-29 | Eli Lilly And Company | Vegf related gene and protein |
| IL138488A0 (en) * | 1998-03-17 | 2001-10-31 | Genentech Inc | Polypeptides homologous to vegf and bmp1 |
| EP0984063A3 (de) * | 1998-08-31 | 2000-08-16 | Eli Lilly And Company | Vegf-verwandtes gen und protein |
| WO2000018212A2 (en) * | 1998-09-30 | 2000-04-06 | Ludwig Institute For Cancer Research | Platelet-derived growth factor c, dna coding therefor, and uses thereof |
| JP2003524383A (ja) * | 1998-10-28 | 2003-08-19 | インサイト・ファーマスーティカルズ・インコーポレイテッド | 成長因子関連分子 |
-
1999
- 1999-12-07 AT AT99966032T patent/ATE404668T1/de active
- 1999-12-07 ES ES99966032T patent/ES2312223T3/es not_active Expired - Lifetime
- 1999-12-07 JP JP2000586908A patent/JP4739526B2/ja not_active Expired - Fee Related
- 1999-12-07 CA CA2354325A patent/CA2354325C/en not_active Expired - Fee Related
- 1999-12-07 AU AU21679/00A patent/AU764039B2/en not_active Ceased
- 1999-12-07 DE DE69939330T patent/DE69939330D1/de not_active Expired - Lifetime
- 1999-12-07 DK DK99966032T patent/DK1137773T3/da active
- 1999-12-07 EP EP08075507.7A patent/EP1988102B1/de not_active Expired - Lifetime
- 1999-12-07 EP EP99966032A patent/EP1137773B1/de not_active Expired - Lifetime
- 1999-12-07 WO PCT/US1999/028968 patent/WO2000034474A2/en not_active Ceased
- 1999-12-07 ES ES08075507T patent/ES2432053T3/es not_active Expired - Lifetime
-
2010
- 2010-11-15 JP JP2010254489A patent/JP5345997B2/ja not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| DE69939330D1 (de) | 2008-09-25 |
| CA2354325C (en) | 2011-08-16 |
| ES2432053T3 (es) | 2013-11-29 |
| WO2000034474A9 (en) | 2002-08-29 |
| ES2312223T3 (es) | 2009-02-16 |
| JP5345997B2 (ja) | 2013-11-20 |
| EP1137773A2 (de) | 2001-10-04 |
| CA2354325A1 (en) | 2000-06-15 |
| DK1137773T3 (da) | 2008-12-08 |
| WO2000034474A3 (en) | 2000-12-28 |
| JP2011052009A (ja) | 2011-03-17 |
| JP4739526B2 (ja) | 2011-08-03 |
| EP1988102B1 (de) | 2013-08-21 |
| AU2167900A (en) | 2000-06-26 |
| EP1988102A1 (de) | 2008-11-05 |
| JP2002531127A (ja) | 2002-09-24 |
| EP1137773B1 (de) | 2008-08-13 |
| AU764039B2 (en) | 2003-08-07 |
| WO2000034474A2 (en) | 2000-06-15 |
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