CO4790156A1 - Polipeptidos de membrana de linfocito de mamifero y acidos nucleicos que los codifican - Google Patents

Polipeptidos de membrana de linfocito de mamifero y acidos nucleicos que los codifican

Info

Publication number
CO4790156A1
CO4790156A1 CO98038990A CO98038990A CO4790156A1 CO 4790156 A1 CO4790156 A1 CO 4790156A1 CO 98038990 A CO98038990 A CO 98038990A CO 98038990 A CO98038990 A CO 98038990A CO 4790156 A1 CO4790156 A1 CO 4790156A1
Authority
CO
Colombia
Prior art keywords
seq
gly
residues
cys
gln
Prior art date
Application number
CO98038990A
Other languages
English (en)
Inventor
Jenny Valladeau
Ravel Odile
Elizabeth Esther Mary Bates
John Ford
Saeland Sem
Serge J E Lebecque
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Publication of CO4790156A1 publication Critical patent/CO4790156A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/7056—Lectin superfamily, e.g. CD23, CD72
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/77—Internalization into the cell

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Cell Biology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

Se describen ácidos nucleicos que codifican varias proteínas decélulas de linfocitos de mamíferos que incluyen primates, los reactivos relacionados con los mismos, incluyendo los anticuerpos específicos, y proteínas purificadas. También se proveen métodos para usar dichos reactivos y equipos de diagnóstico relacionados. Un polipéptido DCMP1 recombinante o sustancialmente puro que exhibe por lo menos una secuencia de identidad de 85% con la SEC ID N°: 2 u 8. Un polipéptido DCMP2 recombinante sustancialmente puro que comprende: a) un polipéptido seleccionado de: 1) Gly Val Ser Glu Leu Gln Glu His Thr Thr Gln Lys Ala His Leu Gly His Cys Pro His Cys Pro Ser Val Cys Val Pro (residuos 118-144 de SEC ID No: 4); 2) Gln Val Ala Thr Leu Asn Asn Asn Ala Ser Thr Glu Gly Thr Cys Cys (residuos 116-181 de SEC ID N°: 4); o 3) Trp Lys Pro Gly Gln Pro Asp Asn Trp Gln Gly His Gly Leu Gly (residuos 263-277 de SEC ID No: 4); o b) Secuencia que exhibe ambas: 1) por lo menos 17 aminoácidos contiguos de DCMP2v tal como se describió en SEC ID N°: 10; y 2) una falta de un segmento de por lo menos 12 aminoácidos contiguos de FKNGPLPLQS LLQRLRWGPC HLLLWLGLGL LLVIIC (residuos 20-56 de SEC ID N°: 4). Las células huésped apropiadas incluyen procariotos, eucariotos inferiores y eucariotos superiores. Los procariotos incluyen los organismos gram negativos y gram positivos, por ejemplo, E. Coli y B. Subtilis. Los eucariotos inferiores incluyen levaduras, por ejemplo S. Verevisiae y Pichia, y especies de los géneros Dictyostelium. Los eucariotos superiores incluyen líneas de células de cultivos de tejidos establecidos a partir de células animales tanto de origen no mamífero como por ejemplo células de insectos y aves como origen de mamífero por ejemplo de seres humanos primates y roedores. ..
CO98038990A 1997-07-09 1998-07-09 Polipeptidos de membrana de linfocito de mamifero y acidos nucleicos que los codifican CO4790156A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US5308097P 1997-07-09 1997-07-09

Publications (1)

Publication Number Publication Date
CO4790156A1 true CO4790156A1 (es) 1999-05-31

Family

ID=21981809

Family Applications (1)

Application Number Title Priority Date Filing Date
CO98038990A CO4790156A1 (es) 1997-07-09 1998-07-09 Polipeptidos de membrana de linfocito de mamifero y acidos nucleicos que los codifican

Country Status (24)

Country Link
US (6) US6277959B1 (es)
EP (2) EP0998496B1 (es)
JP (2) JP2002509438A (es)
KR (1) KR20010021597A (es)
CN (2) CN1493597A (es)
AR (1) AR014891A1 (es)
AT (1) ATE397018T1 (es)
AU (1) AU755279C (es)
BR (1) BR9811675A (es)
CA (1) CA2295308C (es)
CO (1) CO4790156A1 (es)
DE (1) DE69839555D1 (es)
ES (1) ES2308808T3 (es)
HK (1) HK1028249A1 (es)
HU (1) HUP0002472A3 (es)
ID (1) ID26517A (es)
IL (1) IL133494A0 (es)
NO (1) NO20000097L (es)
NZ (1) NZ501777A (es)
PE (1) PE96899A1 (es)
PL (1) PL337942A1 (es)
SK (1) SK252000A3 (es)
WO (1) WO1999002562A1 (es)
ZA (1) ZA986051B (es)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020187131A1 (en) * 1995-01-31 2002-12-12 Daniel Hawiger Enhanced antigen delivery and modulation of the immune response therefrom
US20040258688A1 (en) * 1995-01-31 2004-12-23 Daniel Hawiger Enhanced antigen delivery and modulation of the immune response therefrom
EP1064371A2 (en) * 1998-03-17 2001-01-03 Schering Corporation Isolated mammalian membrane protein genes and related reagents
US7030228B1 (en) 1999-11-15 2006-04-18 Miltenyi Biotec Gmbh Antigen-binding fragments specific for dendritic cells, compositions and methods of use thereof antigens recognized thereby and cells obtained thereby
EP1813626B1 (en) * 1999-11-15 2015-02-18 Miltenyi Biotec GmbH Antigen-binding fragments specific for dendritic cells, compositions and methods of use thereof, antigens recognized thereby and cells obtained thereby
US7560534B2 (en) 2000-05-08 2009-07-14 Celldex Research Corporation Molecular conjugates comprising human monoclonal antibodies to dendritic cells
AU6138301A (en) 2000-05-08 2001-11-20 Medarex Inc Human monoclonal antibodies to dendritic cells
WO2003031578A2 (en) * 2001-10-09 2003-04-17 Immunex Corporation Mammalian c-type lectins
US20060008807A1 (en) * 2002-08-23 2006-01-12 O'hara Shawn M Multiparameter analysis of comprehensive nucleic acids and morphological features on the same sample
US9259459B2 (en) * 2003-01-31 2016-02-16 Celldex Therapeutics Inc. Antibody vaccine conjugates and uses therefor
AU2004213749B2 (en) * 2003-01-31 2010-02-25 Celldex Therapeutics, Inc. Antibody vaccine conjugates and uses therefor
US7547760B2 (en) * 2006-07-03 2009-06-16 West Virginia University Peptides and chemical compound for inhibition of SHP2 function
AU2014240262B2 (en) * 2007-02-02 2016-04-28 Baylor Research Institute Agents that engage antigen - presenting cells through dendritic cell asialoglycoprotein receptor (dc-asgpr)
TWI422594B (zh) 2007-02-02 2014-01-11 Baylor Res Inst 經由樹狀細胞去唾液酸糖蛋白受體（ｄｃ-ａｓｇｐｒ）接合抗原呈現細胞之藥劑
JP5377330B2 (ja) 2007-02-02 2013-12-25 ベイラー リサーチ インスティテュート 抗原提示細胞上に発現されたｄｃｉｒへの抗原のターゲティングに基づくワクチン
EP2224954B1 (en) 2007-11-07 2014-01-08 Celldex Therapeutics, Inc. Antibodies that bind human dendritic and epithelial cell 205 (dec-205)
US20130058957A1 (en) * 2010-02-23 2013-03-07 The University Of Tokyo Dendritic cell immunoreceptor agonist
US8956859B1 (en) 2010-08-13 2015-02-17 Aviex Technologies Llc Compositions and methods for determining successful immunization by one or more vaccines
CA3185180A1 (en) 2014-05-16 2015-11-19 Baylor Research Institute Methods and compositions for treating autoimmune and inflammatory conditions
CN108314740B (zh) * 2018-03-07 2024-02-27 上海晶诺生物科技有限公司 一种蛋白固定化修饰的细胞培养容器

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3645090A (en) 1969-06-19 1972-02-29 Citizen Watch Co Ltd Day-date quick-adjuster for calender timepiece
US3940475A (en) 1970-06-11 1976-02-24 Biological Developments, Inc. Radioimmune method of assaying quantitatively for a hapten
NL154598B (nl) 1970-11-10 1977-09-15 Organon Nv Werkwijze voor het aantonen en bepalen van laagmoleculire verbindingen en van eiwitten die deze verbindingen specifiek kunnen binden, alsmede testverpakking.
US3817837A (en) 1971-05-14 1974-06-18 Syva Corp Enzyme amplification assay
US3939350A (en) 1974-04-29 1976-02-17 Board Of Trustees Of The Leland Stanford Junior University Fluorescent immunoassay employing total reflection for activation
US3996345A (en) 1974-08-12 1976-12-07 Syva Company Fluorescence quenching with immunological pairs in immunoassays
US4277437A (en) 1978-04-05 1981-07-07 Syva Company Kit for carrying out chemically induced fluorescence immunoassay
US4275149A (en) 1978-11-24 1981-06-23 Syva Company Macromolecular environment control in specific receptor assays
US4391904A (en) 1979-12-26 1983-07-05 Syva Company Test strip kits in immunoassays and compositions therein
US4366241A (en) 1980-08-07 1982-12-28 Syva Company Concentrating zone method in heterogeneous immunoassays
US4659678A (en) 1982-09-29 1987-04-21 Serono Diagnostics Limited Immunoassay of antigens
NZ207394A (en) 1983-03-08 1987-03-06 Commw Serum Lab Commission Detecting or determining sequence of amino acids
US4816567A (en) 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
US4859609A (en) 1986-04-30 1989-08-22 Genentech, Inc. Novel receptors for efficient determination of ligands and their antagonists or agonists

Also Published As

Publication number Publication date
CN100391973C (zh) 2008-06-04
US7034137B2 (en) 2006-04-25
PE96899A1 (es) 1999-10-05
US20070116703A1 (en) 2007-05-24
WO1999002562A1 (en) 1999-01-21
ATE397018T1 (de) 2008-06-15
EP0998496A1 (en) 2000-05-10
AU8271298A (en) 1999-02-08
US7691373B2 (en) 2010-04-06
EP1980573A3 (en) 2009-06-10
US6756478B2 (en) 2004-06-29
CN1262689A (zh) 2000-08-09
ES2308808T3 (es) 2008-12-01
BR9811675A (pt) 2000-09-19
AR014891A1 (es) 2001-04-11
JP2008264000A (ja) 2008-11-06
IL133494A0 (en) 2001-04-30
CA2295308A1 (en) 1999-01-21
EP1980573A2 (en) 2008-10-15
US20040192892A1 (en) 2004-09-30
US6277959B1 (en) 2001-08-21
AU755279B2 (en) 2002-12-05
CN1493597A (zh) 2004-05-05
CA2295308C (en) 2010-12-14
US20110244513A1 (en) 2011-10-06
EP0998496B1 (en) 2008-05-28
NO20000097D0 (no) 2000-01-07
HUP0002472A2 (hu) 2000-10-28
AU755279C (en) 2004-02-19
US20020165346A1 (en) 2002-11-07
KR20010021597A (ko) 2001-03-15
US20060074234A1 (en) 2006-04-06
ZA986051B (en) 1999-01-18
ID26517A (id) 2001-01-11
JP2002509438A (ja) 2002-03-26
HUP0002472A3 (en) 2003-08-28
US7179467B2 (en) 2007-02-20
SK252000A3 (en) 2000-09-12
PL337942A1 (en) 2000-09-11
DE69839555D1 (de) 2008-07-10
NZ501777A (en) 2001-10-26
NO20000097L (no) 2000-03-09
HK1028249A1 (en) 2001-02-09

Similar Documents

Publication Publication Date Title
CO4790156A1 (es) Polipeptidos de membrana de linfocito de mamifero y acidos nucleicos que los codifican
Bietlot et al. Facile preparation and characterization of the toxin from Bacillus thuringiensis var. kurstaki
ATE546533T1 (de) Rekombinante expression von proteinen in einer disulfidverbrückten, zweikettigen form
HUP0101136A2 (hu) Fehérjeexpresszió baculovírus-vektort alkalmazó expressziós rendszerben
DE69939330D1 (de) Wachstumsfaktor-homologe zvegf-3
DK1218751T3 (da) Cöliakidiagnose under anvendelse af et gliadinepitop
NL300013I1 (nl) Nieuwe protein met TNF-remmende werking en hun ber
DE68929043D1 (de) Für androgen-rezeptor-protein kodierende dna
KR920701451A (ko) 인체혈청알부민의 n-말단 단편을 함유하는 융합 단백질
DK80886D0 (da) Biologisk aktive proteiner samt fremgangsmaade til deres fremstillingog anvendelse
ES2120964T3 (es) Peptidos osteogenicos.
KR910700264A (ko) 소마토트로핀 유사물
BR1100650A (pt) Proteìnas de superfìcie cd44 variantes, sequências de dna que as codificam, anticorpos contra estas proteìnas, bem como a sua utilização no diagnóstico e na terapia
MD1652G2 (ro) Proteină cu activitate de tip citochină, ADN recombinant, codificator pentru această proteină, celule şi microorganisme transformate, vector de expresie, procedeu de obţinere a proteinei şi remediu care conţine această proteină
DK491487A (da) Dna-sekvens til ekspressionering af biologisk aktivt faktor xiii og anvendelse af samme
DK0479912T3 (da) Fremgangsmåde til hæmning af N-endereglens forløb i levende celler
Vandekerckhove et al. Amino acid sequence of Acanthamoeba actin
EP0992586A3 (en) Extracellular matrix proteins with modified amino acid
ATE253639T1 (de) Verfahren zur herstellung von peptiden
DE3881023D1 (de) Proteine, expressionsvektoren, die fuer solche proteine kodierende dna enthalten und zellen, die solche expressionsvektoren enthalten.
KR920703814A (ko) 공유결합 안지오제닌/리보핵산가수분해효소 하이브라이드
MXPA01011158A (es) Factor de crecimiento homologo zvegf4.
DE69634757D1 (de) Vektor zur expression von n-terminal verlängerten proteinen in hefezellen
KR920703636A (ko) 온코스타틴 m 활성을 가진 신규한 단백질과 그 제조과정
Slavkin Report on the Questionnaire Survey