YU59100A - Postupak za dobijanje pirazolo (4,3-d) pirimidin-7-ona-3-piridilsulfonil jedinjenja i njihova intermedijera - Google Patents
Postupak za dobijanje pirazolo (4,3-d) pirimidin-7-ona-3-piridilsulfonil jedinjenja i njihova intermedijeraInfo
- Publication number
- YU59100A YU59100A YU59100A YUP59100A YU59100A YU 59100 A YU59100 A YU 59100A YU 59100 A YU59100 A YU 59100A YU P59100 A YUP59100 A YU P59100A YU 59100 A YU59100 A YU 59100A
- Authority
- YU
- Yugoslavia
- Prior art keywords
- compounds
- pyridylsulphonyl
- pyrazolo
- pyrimidin
- intermediates
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Reproductive Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Gynecology & Obstetrics (AREA)
- Endocrinology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyridine Compounds (AREA)
Abstract
Obezbedjen je postupak za dobijanje jedinjenja formule (I) koji obuhvata reagovanje jedinjenja formule (II), (III) ili (IV) u prisustvu OR i agensa za hvatanje hidroksida ili u slučaju jedinjenja formule (IV) reagovanje u prisustvu pomoćne baze i agensa za hvatanje hidroksida (tj OR je supstituisan pomoću pomoćne baze), gde X je odlazeća grupa i R1 do R4 su kao što je definisano napred.[Process has been secured for obtaining compounds of formula (I) encompassing the reactions of the compounds of formula (II), (III) or (IV) in the presence of OR and agents for the capturing of hydroxides or in the case compounds of formula (IV) encompassing the reactions of the bases and agents for the capturing of hydroxides (i.e. OR is substituted by means of auxilliary base), where x is the outgoing group and R1 to R4 are as previously defined.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9924042.6A GB9924042D0 (en) | 1999-10-11 | 1999-10-11 | Process for thr preparation of pyrazolo[4,3-D]pyrimidin-7-ones-3-pyridylsulphonyl compounds and intermediates thereof |
| GB0018667A GB0018667D0 (en) | 2000-07-28 | 2000-07-28 | Process for the preparation of pyrazolo [4,3-d] Pyrimidin-7-ones-3-pyridylsulphonyl compounds and intermediates thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| YU59100A true YU59100A (sh) | 2003-10-31 |
Family
ID=26244761
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| YU59100A YU59100A (sh) | 1999-10-11 | 2000-09-29 | Postupak za dobijanje pirazolo (4,3-d) pirimidin-7-ona-3-piridilsulfonil jedinjenja i njihova intermedijera |
Country Status (39)
| Country | Link |
|---|---|
| EP (1) | EP1092720B1 (sh) |
| JP (1) | JP2001114783A (sh) |
| KR (1) | KR100395718B1 (sh) |
| CN (1) | CN1292379A (sh) |
| AR (1) | AR029767A1 (sh) |
| AT (1) | ATE286899T1 (sh) |
| AU (1) | AU6543600A (sh) |
| BG (1) | BG104840A (sh) |
| BR (1) | BR0004787A (sh) |
| CA (1) | CA2322995A1 (sh) |
| CO (1) | CO5251476A1 (sh) |
| CZ (1) | CZ20003754A3 (sh) |
| DE (1) | DE60017330D1 (sh) |
| DZ (1) | DZ3096A1 (sh) |
| EA (1) | EA003145B1 (sh) |
| EE (1) | EE200000537A (sh) |
| EG (1) | EG22775A (sh) |
| GT (1) | GT200000169A (sh) |
| HR (1) | HRP20000674A2 (sh) |
| HU (1) | HUP0003979A3 (sh) |
| ID (1) | ID27539A (sh) |
| IL (1) | IL138913A0 (sh) |
| IN (1) | IN190477B (sh) |
| IS (1) | IS5654A (sh) |
| MA (1) | MA25867A1 (sh) |
| MX (1) | MXPA00009936A (sh) |
| NO (1) | NO316072B1 (sh) |
| NZ (1) | NZ507431A (sh) |
| OA (1) | OA11495A (sh) |
| PA (1) | PA8504601A1 (sh) |
| PE (1) | PE20010682A1 (sh) |
| PL (1) | PL343140A1 (sh) |
| SG (1) | SG97950A1 (sh) |
| SK (1) | SK15052000A3 (sh) |
| SV (1) | SV2002000194A (sh) |
| TN (1) | TNSN00195A1 (sh) |
| TR (1) | TR200002959A2 (sh) |
| UY (1) | UY26388A1 (sh) |
| YU (1) | YU59100A (sh) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| TWI265925B (en) | 1999-10-11 | 2006-11-11 | Pfizer | Pyrazolo[4,3-d]pyrimidin-7-ones useful in inhibiting type 5 cyclic guanosine 3',5'-monophosphate phosphodiesterases(cGMP PDE5), process and intermediates for their preparation, their uses and composition comprising them |
| YU59100A (sh) * | 1999-10-11 | 2003-10-31 | Pfizer Inc. | Postupak za dobijanje pirazolo (4,3-d) pirimidin-7-ona-3-piridilsulfonil jedinjenja i njihova intermedijera |
| US6809200B2 (en) * | 2000-07-28 | 2004-10-26 | Pfizer Inc. | Process for the preparation of pyrazolo[4,3-d]pyrimidin-7-one compounds and intermediates thereof |
| JP2006219373A (ja) * | 2003-06-13 | 2006-08-24 | Daiichi Asubio Pharma Co Ltd | Ｐｄｅ７阻害作用を有するピリジニルピラゾロピリミジノン誘導体 |
| ES2343141T3 (es) * | 2005-11-16 | 2010-07-23 | F. Hoffmann-La Roche Ag | Nuevo procedimiento para la preparacion de thoc. |
| KR101002490B1 (ko) * | 2007-06-09 | 2010-12-17 | 동아제약주식회사 | 유데나필을 유효성분으로 함유하는 만성 심부전증 치료용약학적 조성물 |
| PE20140236A1 (es) * | 2011-02-23 | 2014-03-14 | Pfizer | IMIDAZO[5,1-f][1,2,4]TRIAZINAS PARA EL TRATAMIENTO DE TRASTORNOS NEUROLOGICOS |
| UA125630C2 (uk) * | 2016-11-21 | 2022-05-04 | Адама Аган Лтд. | Спосіб одержання метоксиметилпіридиндикарбоксилату |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SK285991B6 (sk) * | 1997-04-25 | 2008-01-07 | Pfizer Inc. | Pyrazolopyrimidinóny, spôsob a medziprodukty na ich výrobu, ich použitie a farmaceutické a veterinárne kompozície na ich báze |
| CN1134442C (zh) * | 1998-04-20 | 2004-01-14 | 美国辉瑞有限公司 | 吡唑并嘧啶酮cGMP PDE5抑制剂、其制备方法及用途及中间体 |
| GB9823101D0 (en) * | 1998-10-23 | 1998-12-16 | Pfizer Ltd | Pharmaceutically active compounds |
| KR100353014B1 (ko) * | 1998-11-11 | 2002-09-18 | 동아제약 주식회사 | 발기부전 치료에 효과를 갖는 피라졸로피리미디논 화합물 |
| YU59100A (sh) * | 1999-10-11 | 2003-10-31 | Pfizer Inc. | Postupak za dobijanje pirazolo (4,3-d) pirimidin-7-ona-3-piridilsulfonil jedinjenja i njihova intermedijera |
-
2000
- 2000-09-29 YU YU59100A patent/YU59100A/sh unknown
- 2000-10-05 IL IL13891300A patent/IL138913A0/xx unknown
- 2000-10-06 CA CA002322995A patent/CA2322995A1/en not_active Abandoned
- 2000-10-06 OA OA1200000272A patent/OA11495A/en unknown
- 2000-10-09 ID IDP20000871D patent/ID27539A/id unknown
- 2000-10-09 SG SG200005769A patent/SG97950A1/en unknown
- 2000-10-09 EG EG20001282A patent/EG22775A/xx active
- 2000-10-09 SK SK1505-2000A patent/SK15052000A3/sk unknown
- 2000-10-10 PA PA20008504601A patent/PA8504601A1/es unknown
- 2000-10-10 NO NO20005104A patent/NO316072B1/no not_active IP Right Cessation
- 2000-10-10 AT AT00308915T patent/ATE286899T1/de not_active IP Right Cessation
- 2000-10-10 EA EA200000924A patent/EA003145B1/ru not_active IP Right Cessation
- 2000-10-10 AR ARP000105334A patent/AR029767A1/es not_active Application Discontinuation
- 2000-10-10 EP EP00308915A patent/EP1092720B1/en not_active Expired - Lifetime
- 2000-10-10 MX MXPA00009936A patent/MXPA00009936A/es active IP Right Grant
- 2000-10-10 KR KR20000059435A patent/KR100395718B1/ko not_active IP Right Cessation
- 2000-10-10 DZ DZ000144A patent/DZ3096A1/xx active
- 2000-10-10 MA MA26085A patent/MA25867A1/fr unknown
- 2000-10-10 DE DE60017330T patent/DE60017330D1/de not_active Expired - Lifetime
- 2000-10-10 GT GT200000169A patent/GT200000169A/es unknown
- 2000-10-10 CZ CZ20003754A patent/CZ20003754A3/cs unknown
- 2000-10-10 TN TNTNSN00195A patent/TNSN00195A1/fr unknown
- 2000-10-10 NZ NZ507431A patent/NZ507431A/xx unknown
- 2000-10-10 IS IS5654A patent/IS5654A/is unknown
- 2000-10-10 UY UY26388A patent/UY26388A1/es not_active Application Discontinuation
- 2000-10-11 PE PE2000001091A patent/PE20010682A1/es not_active Application Discontinuation
- 2000-10-11 PL PL00343140A patent/PL343140A1/xx not_active Application Discontinuation
- 2000-10-11 CO CO00077465A patent/CO5251476A1/es not_active Application Discontinuation
- 2000-10-11 AU AU65436/00A patent/AU6543600A/en not_active Abandoned
- 2000-10-11 BG BG104840A patent/BG104840A/bg unknown
- 2000-10-11 CN CN001317067A patent/CN1292379A/zh active Pending
- 2000-10-11 BR BR0004787-2A patent/BR0004787A/pt not_active IP Right Cessation
- 2000-10-11 EE EEP200000537A patent/EE200000537A/xx unknown
- 2000-10-11 SV SV2000000194A patent/SV2002000194A/es unknown
- 2000-10-11 JP JP2000310705A patent/JP2001114783A/ja not_active Withdrawn
- 2000-10-11 TR TR2000/02959A patent/TR200002959A2/xx unknown
- 2000-10-11 HR HR20000674A patent/HRP20000674A2/hr not_active Application Discontinuation
- 2000-10-11 HU HU0003979A patent/HUP0003979A3/hu unknown
- 2000-10-16 IN IN902MU2000 patent/IN190477B/en unknown
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