AR029767A1 - Procedimiento para la preparacion de compuestos de pirazolo (4, 3-d) pirimidin-7-onas-3-piridilsulfonilo y compuestos intermediarios utiles en dicho procedimiento. - Google Patents

Procedimiento para la preparacion de compuestos de pirazolo (4, 3-d) pirimidin-7-onas-3-piridilsulfonilo y compuestos intermediarios utiles en dicho procedimiento.

Info

Publication number
AR029767A1
AR029767A1 ARP000105334A ARP000105334A AR029767A1 AR 029767 A1 AR029767 A1 AR 029767A1 AR P000105334 A ARP000105334 A AR P000105334A AR P000105334 A ARP000105334 A AR P000105334A AR 029767 A1 AR029767 A1 AR 029767A1
Authority
AR
Argentina
Prior art keywords
procedure
compounds
preparation
piridilsulfonilo
pirazolo
Prior art date
Application number
ARP000105334A
Other languages
English (en)
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GBGB9924042.6A external-priority patent/GB9924042D0/en
Priority claimed from GB0018667A external-priority patent/GB0018667D0/en
Application filed by Pfizer filed Critical Pfizer
Publication of AR029767A1 publication Critical patent/AR029767A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Abstract

Se proporciona un procedimiento para la preparacion de los compuestos de formula 1, que comprende la reaccion de un compuesto de formula (2), (3) o (4) en presencia de OR y un agente de captura de hidroxido o, en el caso de compuestos de formula (4), la reaccion en presencia de una base auxiliar y un agente de captura de hidroxido (es decir, OR se sustituye por la base auxiliar), siendo X un grupo saliente y siendo R1 a R4 como se han definido en la memoria.
ARP000105334A 1999-10-11 2000-10-10 Procedimiento para la preparacion de compuestos de pirazolo (4, 3-d) pirimidin-7-onas-3-piridilsulfonilo y compuestos intermediarios utiles en dicho procedimiento. AR029767A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9924042.6A GB9924042D0 (en) 1999-10-11 1999-10-11 Process for thr preparation of pyrazolo[4,3-D]pyrimidin-7-ones-3-pyridylsulphonyl compounds and intermediates thereof
GB0018667A GB0018667D0 (en) 2000-07-28 2000-07-28 Process for the preparation of pyrazolo [4,3-d] Pyrimidin-7-ones-3-pyridylsulphonyl compounds and intermediates thereof

Publications (1)

Publication Number Publication Date
AR029767A1 true AR029767A1 (es) 2003-07-16

Family

ID=26244761

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP000105334A AR029767A1 (es) 1999-10-11 2000-10-10 Procedimiento para la preparacion de compuestos de pirazolo (4, 3-d) pirimidin-7-onas-3-piridilsulfonilo y compuestos intermediarios utiles en dicho procedimiento.

Country Status (39)

Country Link
EP (1) EP1092720B1 (es)
JP (1) JP2001114783A (es)
KR (1) KR100395718B1 (es)
CN (1) CN1292379A (es)
AR (1) AR029767A1 (es)
AT (1) ATE286899T1 (es)
AU (1) AU6543600A (es)
BG (1) BG104840A (es)
BR (1) BR0004787A (es)
CA (1) CA2322995A1 (es)
CO (1) CO5251476A1 (es)
CZ (1) CZ20003754A3 (es)
DE (1) DE60017330D1 (es)
DZ (1) DZ3096A1 (es)
EA (1) EA003145B1 (es)
EE (1) EE200000537A (es)
EG (1) EG22775A (es)
GT (1) GT200000169A (es)
HR (1) HRP20000674A2 (es)
HU (1) HUP0003979A3 (es)
ID (1) ID27539A (es)
IL (1) IL138913A0 (es)
IN (1) IN190477B (es)
IS (1) IS5654A (es)
MA (1) MA25867A1 (es)
MX (1) MXPA00009936A (es)
NO (1) NO316072B1 (es)
NZ (1) NZ507431A (es)
OA (1) OA11495A (es)
PA (1) PA8504601A1 (es)
PE (1) PE20010682A1 (es)
PL (1) PL343140A1 (es)
SG (1) SG97950A1 (es)
SK (1) SK15052000A3 (es)
SV (1) SV2002000194A (es)
TN (1) TNSN00195A1 (es)
TR (1) TR200002959A2 (es)
UY (1) UY26388A1 (es)
YU (1) YU59100A (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI265925B (en) 1999-10-11 2006-11-11 Pfizer Pyrazolo[4,3-d]pyrimidin-7-ones useful in inhibiting type 5 cyclic guanosine 3',5'-monophosphate phosphodiesterases(cGMP PDE5), process and intermediates for their preparation, their uses and composition comprising them
YU59100A (sh) * 1999-10-11 2003-10-31 Pfizer Inc. Postupak za dobijanje pirazolo (4,3-d) pirimidin-7-ona-3-piridilsulfonil jedinjenja i njihova intermedijera
US6809200B2 (en) * 2000-07-28 2004-10-26 Pfizer Inc. Process for the preparation of pyrazolo[4,3-d]pyrimidin-7-one compounds and intermediates thereof
JP2006219373A (ja) * 2003-06-13 2006-08-24 Daiichi Asubio Pharma Co Ltd Ｐｄｅ７阻害作用を有するピリジニルピラゾロピリミジノン誘導体
CA2629077C (en) * 2005-11-16 2014-03-18 F. Hoffmann-La Roche Ag Novel process for the preparation of thoc
KR101002490B1 (ko) * 2007-06-09 2010-12-17 동아제약주식회사 유데나필을 유효성분으로 함유하는 만성 심부전증 치료용약학적 조성물
EP2681218A1 (en) * 2011-02-23 2014-01-08 Pfizer Inc IMIDAZO[5,1-f][1,2,4]TRIAZINES FOR THE TREATMENT OF NEUROLOGICAL DISORDERS
EP3541787A1 (en) * 2016-11-21 2019-09-25 Adama Agan Ltd. Process for preparing methoxy methyl pyridine dicarboxylate

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL336586A1 (en) * 1997-04-25 2000-07-03 Pfizer Pyrazoylpyrimidinones inhibiting the cyclic guanosine 3',5'-monophosphate phosphodiesterase of type 5 (cgmp pde5) for treating sexual disorders
HUP0102543A3 (en) * 1998-04-20 2002-01-28 Pfizer Pyrazolopyrimidinone cgmp pde5 inhibitors for the treatment of sexual dysfunction and medicaments containing them
GB9823101D0 (en) * 1998-10-23 1998-12-16 Pfizer Ltd Pharmaceutically active compounds
KR100353014B1 (ko) * 1998-11-11 2002-09-18 동아제약 주식회사 발기부전 치료에 효과를 갖는 피라졸로피리미디논 화합물
YU59100A (sh) * 1999-10-11 2003-10-31 Pfizer Inc. Postupak za dobijanje pirazolo (4,3-d) pirimidin-7-ona-3-piridilsulfonil jedinjenja i njihova intermedijera

Also Published As

Publication number Publication date
PA8504601A1 (es) 2002-02-21
PL343140A1 (en) 2001-04-23
HU0003979D0 (en) 2000-12-28
EA200000924A3 (ru) 2001-06-25
NZ507431A (en) 2002-09-27
BG104840A (bg) 2001-10-31
HRP20000674A2 (en) 2001-08-31
EG22775A (en) 2003-08-31
EP1092720B1 (en) 2005-01-12
CO5251476A1 (es) 2003-02-28
EP1092720A3 (en) 2001-09-19
BR0004787A (pt) 2001-05-22
NO316072B1 (no) 2003-12-08
MA25867A1 (fr) 2003-10-01
KR20010050935A (ko) 2001-06-25
KR100395718B1 (ko) 2003-08-25
PE20010682A1 (es) 2001-07-04
UY26388A1 (es) 2001-05-31
SG97950A1 (en) 2003-08-20
JP2001114783A (ja) 2001-04-24
GT200000169A (es) 2002-04-03
CN1292379A (zh) 2001-04-25
DE60017330D1 (de) 2005-02-17
YU59100A (sh) 2003-10-31
IN190477B (es) 2003-08-02
IS5654A (is) 2001-04-12
EP1092720A2 (en) 2001-04-18
CZ20003754A3 (cs) 2002-06-12
TNSN00195A1 (fr) 2005-11-10
HUP0003979A3 (en) 2002-03-28
EA003145B1 (ru) 2003-02-27
AU6543600A (en) 2001-04-12
DZ3096A1 (fr) 2004-06-20
NO20005104D0 (no) 2000-10-10
OA11495A (en) 2004-05-05
EE200000537A (et) 2001-06-15
ATE286899T1 (de) 2005-01-15
HUP0003979A2 (hu) 2001-12-28
IL138913A0 (en) 2001-11-25
SK15052000A3 (sk) 2003-01-09
EA200000924A2 (ru) 2001-04-23
CA2322995A1 (en) 2001-04-11
NO20005104L (no) 2001-04-17
TR200002959A2 (tr) 2001-07-23
ID27539A (id) 2001-04-12
SV2002000194A (es) 2002-01-23
MXPA00009936A (es) 2002-10-23

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