DE60029561T2 - Immobilisierung von molekülen auf oberflächen über polymerbürsten - Google Patents
Immobilisierung von molekülen auf oberflächen über polymerbürsten Download PDFInfo
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- DE60029561T2 DE60029561T2 DE60029561T DE60029561T DE60029561T2 DE 60029561 T2 DE60029561 T2 DE 60029561T2 DE 60029561 T DE60029561 T DE 60029561T DE 60029561 T DE60029561 T DE 60029561T DE 60029561 T2 DE60029561 T2 DE 60029561T2
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Classifications
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- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54353—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals with ligand attached to the carrier via a chemical coupling agent
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
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- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/544—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being organic
- G01N33/545—Synthetic resin
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- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
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- B01J2219/00529—DNA chips
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- B—PERFORMING OPERATIONS; TRANSPORTING
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- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
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- B01J2219/00585—Parallel processes
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- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
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- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00596—Solid-phase processes
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- B—PERFORMING OPERATIONS; TRANSPORTING
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- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
- B01J2219/00608—DNA chips
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- B—PERFORMING OPERATIONS; TRANSPORTING
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- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
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- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
- B01J2219/00612—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports the surface being inorganic
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- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
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- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
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- B01J2219/00626—Covalent
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- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
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- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
- B01J2219/00632—Introduction of reactive groups to the surface
- B01J2219/00637—Introduction of reactive groups to the surface by coating it with another layer
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00659—Two-dimensional arrays
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00718—Type of compounds synthesised
- B01J2219/0072—Organic compounds
- B01J2219/00722—Nucleotides
-
- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B40/00—Libraries per se, e.g. arrays, mixtures
- C40B40/04—Libraries containing only organic compounds
- C40B40/06—Libraries containing nucleotides or polynucleotides, or derivatives thereof
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Microbiology (AREA)
- Organic Chemistry (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- General Physics & Mathematics (AREA)
- Zoology (AREA)
- Food Science & Technology (AREA)
- Pathology (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Cell Biology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biophysics (AREA)
- General Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
- Polymerisation Methods In General (AREA)
- Polymerization Catalysts (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
- Compositions Of Macromolecular Compounds (AREA)
- Materials For Medical Uses (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP99101340 | 1999-01-25 | ||
| EP99101340 | 1999-01-25 | ||
| EP99104278A EP1035218A1 (en) | 1999-03-03 | 1999-03-03 | Immobilization of molecules on surfaces via polymer brushes |
| EP99104278 | 1999-03-03 | ||
| PCT/EP2000/000554 WO2000043539A2 (en) | 1999-01-25 | 2000-01-25 | Immobilization of molecules on surfaces via polymer brushes |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE60029561D1 DE60029561D1 (de) | 2006-09-07 |
| DE60029561T2 true DE60029561T2 (de) | 2007-07-19 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60029561T Expired - Lifetime DE60029561T2 (de) | 1999-01-25 | 2000-01-25 | Immobilisierung von molekülen auf oberflächen über polymerbürsten |
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| Country | Link |
|---|---|
| US (1) | US7250253B1 (https=) |
| EP (1) | EP1144677B1 (https=) |
| JP (1) | JP4970654B2 (https=) |
| AT (1) | ATE334226T1 (https=) |
| AU (1) | AU3150400A (https=) |
| CA (1) | CA2360027A1 (https=) |
| DE (1) | DE60029561T2 (https=) |
| WO (1) | WO2000043539A2 (https=) |
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| DE60027309T2 (de) | 1999-07-02 | 2006-08-31 | Symyx Technologies, Inc., Santa Clara | Polymerverzweigungen zur immobilisierung von molekülen auf oberflächen oder substraten, wobei die polymere wasserlösliche oder wasserdispergierbare segmente und sonden aufweisen |
| KR100608152B1 (ko) * | 1999-07-07 | 2006-08-04 | 미러스 코포레이션 | 고체 지지체 상에 핵산을 고정시키기 위한 기판 |
| CA2317179A1 (en) | 1999-09-01 | 2001-03-01 | Affymetrix, Inc. | Macromolecular arrays on polymeric brushes and methods for preparing the same |
| FR2802550B1 (fr) * | 1999-12-17 | 2004-03-05 | Centre Nat Rech Scient | Biopuces, preparation et utilisations |
| DE60033648T2 (de) * | 2000-07-27 | 2007-11-08 | Micronas Holding Gmbh | Auf einer Oberfläche befestigte polyfunktionelle Polymernetzwerke für Sensorchips |
| ATE316581T1 (de) | 2000-09-05 | 2006-02-15 | Zeltz Patrick Dr | Verfahren zur spezifischen bestimmung von dna- sequenzen mittels paralleler amplifikation |
| ATE355526T1 (de) * | 2000-10-31 | 2006-03-15 | Micronas Gmbh | Gemusterte polymeroberflächen geeignet für biokonjugationen und verfahren zu ihrer herstellung |
| WO2002056021A2 (en) * | 2001-01-10 | 2002-07-18 | Symyx Technologies Inc | Polymer brushes for immobilizing molecules to a surface |
| US20030068317A1 (en) * | 2001-04-20 | 2003-04-10 | William Lee | High capacity methods for separation, purification, concentration, immobilization and synthesis of compounds and applications based thereupon |
| EP1572896A4 (en) * | 2001-07-30 | 2006-06-07 | Angiotech Biocoatings Corp | PFROPFPOLYMERMATRIZES |
| AU2002361223A1 (en) * | 2001-08-27 | 2003-03-18 | Zeptosens Ag | Bioanalytical recognition surface with optimised recognition element density |
| US6867295B2 (en) | 2001-09-07 | 2005-03-15 | Dionex Corporation | Ion exchange cryptands covalently bound to substrates |
| AU2002360298A1 (en) * | 2001-12-10 | 2003-06-23 | Emembrane, Inc. | Functionalized materials and libraries thereof |
| JP2003294742A (ja) * | 2002-03-29 | 2003-10-15 | Inst Of Physical & Chemical Res | ハイブリダイゼーション用基板及びその使用方法 |
| US20060111517A1 (en) * | 2002-08-08 | 2006-05-25 | Hans-Dieter Feucht | Recognition layers made of hydrogel based on polyacrylamide for use in biosensor technology |
| DE60312525T2 (de) * | 2002-08-09 | 2007-12-06 | Ottawa Health Research Institute, Ottawa | Biosynthetische matrix und deren verwendung |
| AU2003270769A1 (en) * | 2002-09-18 | 2004-04-08 | Emembrane, Inc. | Functionalized materials and methods of using same |
| DE10245435B4 (de) | 2002-09-27 | 2006-03-16 | Micronas Gmbh | Vorrichtung zur Detektion mindestens eines in einer zu untersuchenden Probe enthaltenen Liganden |
| DE10328730B4 (de) * | 2003-06-25 | 2006-08-17 | Micronas Gmbh | Verfahren zum Herstellen eines Microarrays und Vorrichtung zum Versehen eines Trägers für ein Microarray mit Beschichtungsstoffen |
| US7354706B2 (en) | 2003-09-09 | 2008-04-08 | The Regents Of The University Of Colorado, A Body Corporate | Use of photopolymerization for amplification and detection of a molecular recognition event |
| US20090163375A1 (en) | 2003-09-09 | 2009-06-25 | Bowman Christopher N | Use of Photopolymerization for Amplification and Detection of a Molecular Recognition Event |
| DE102004010430A1 (de) | 2004-03-01 | 2005-09-22 | Rühe, Jürgen, Prof. Dr. | Verfahren zur kovalenten Immobilisierung von Biomolekülen an organischen Oberflächen |
| US7514764B2 (en) * | 2005-03-23 | 2009-04-07 | Wisconsin Alumni Research Foundation | Materials and methods for creating imaging layers |
| DE102005022782A1 (de) | 2005-05-12 | 2006-11-16 | Tesa Ag | Haftklebemassen und Verfahren zu deren Herstellung |
| WO2006128644A1 (en) * | 2005-05-30 | 2006-12-07 | Giovanna Pirri | Polymer coating and functionalization of solid surfaces |
| US8357433B2 (en) | 2005-06-14 | 2013-01-22 | Siemens Energy, Inc. | Polymer brushes |
| US7862886B2 (en) * | 2005-08-12 | 2011-01-04 | Fujifilm Corporation | Optical film, antireflection film, processes for producing the same, and polarizing plate and display employing the same |
| EP1811300B1 (de) | 2005-12-23 | 2008-11-12 | Micronas GmbH | Sensorchip mit in einem Polymer-Netzwerk eingelagerten Rezeptoren |
| KR100838124B1 (ko) * | 2007-02-01 | 2008-06-13 | 포항공과대학교 산학협력단 | 생체적합성 지방족 브러쉬 고분자 및 그 제조 방법 |
| DE102008032570A1 (de) | 2008-07-11 | 2010-01-14 | Tesa Se | Haftklebemassen und Verfahren zu deren Herstellung |
| EP2192409B1 (en) | 2008-11-26 | 2014-04-23 | Corning Incorporated | Label independent detection biosensor composition and methods thereof |
| DE102009060626A1 (de) | 2009-12-24 | 2011-06-30 | Klapproth, Holger, Dr., 79108 | Kalibrierte Flusszelle zur IR-Analytik |
| EP2598562A4 (en) * | 2010-07-30 | 2014-01-15 | United Resource Recovery Corp | SURFACE FUNCTIONALIZATION OF POLYESTERS |
| US20130316430A1 (en) | 2011-02-01 | 2013-11-28 | Maharshi Dayanand University | Polyvinyl chloride surface co-immobilized with enzymes and uses thereof |
| EP2718691B1 (de) | 2011-06-09 | 2017-12-13 | QFood GmbH | Verfahren und vorrichtung zum bestimmen der konzentration eines in einer flüssigen probe enthaltenen analyten |
| EP2812091B1 (en) | 2012-09-17 | 2021-03-10 | W.R. Grace & CO. - CONN. | Chromatography media and devices |
| EP2811983B1 (en) | 2012-09-17 | 2019-05-01 | W.R. Grace & CO. - CONN. | Functionalized particulate support material and methods of making and using the same |
| JP6453210B2 (ja) | 2013-05-13 | 2019-01-16 | 国立研究開発法人科学技術振興機構 | 新規複合材料およびそれを用いるポリマー被覆材前駆体 |
| CN107002117B (zh) | 2013-12-05 | 2021-12-10 | 生捷科技控股公司 | 核酸测序方法 |
| US10385335B2 (en) | 2013-12-05 | 2019-08-20 | Centrillion Technology Holdings Corporation | Modified surfaces |
| CN106460032B (zh) | 2013-12-05 | 2019-12-24 | 生捷科技控股公司 | 图案化阵列的制备 |
| ES2887110T3 (es) | 2014-01-16 | 2021-12-21 | Grace W R & Co | Medios para cromatografía de afinidad y dispositivos para cromatografía |
| US11060139B2 (en) | 2014-03-28 | 2021-07-13 | Centrillion Technology Holdings Corporation | Methods for sequencing nucleic acids |
| PL3137209T3 (pl) | 2014-05-02 | 2023-01-02 | W.R. Grace & Co. - Conn. | Funkcjonalizowany materiał nośnikowy i sposoby wytwarzania oraz stosowania funkcjonalizowanego materiału nośnikowego |
| KR102566292B1 (ko) | 2015-06-05 | 2023-08-10 | 더블유.알. 그레이스 앤드 캄파니-콘. | 흡착성 바이오프로세싱 정화제와 이의 제조 및 사용 방법 |
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| JPS63233360A (ja) * | 1986-12-15 | 1988-09-29 | Fuji Photo Film Co Ltd | 電気泳動用媒体 |
| SE8801070D0 (sv) * | 1988-03-23 | 1988-03-23 | Pharmacia Ab | Method for immobilizing a dna sequence on a solid support |
| SE462454B (sv) | 1988-11-10 | 1990-06-25 | Pharmacia Ab | Maetyta foer anvaendning i biosensorer |
| US5143854A (en) * | 1989-06-07 | 1992-09-01 | Affymax Technologies N.V. | Large scale photolithographic solid phase synthesis of polypeptides and receptor binding screening thereof |
| JPH05502585A (ja) * | 1989-12-04 | 1993-05-13 | ベクトン ディッキンソン アンド カンパニー | ポリマーに共有結合したオリゴヌクレオチドの利用により向上される標的核酸の捕獲 |
| BR9206705A (pt) * | 1991-11-01 | 1995-11-21 | Adelaide Children S Hospital | Processo de amplificação de fase sólida |
| US5624711A (en) * | 1995-04-27 | 1997-04-29 | Affymax Technologies, N.V. | Derivatization of solid supports and methods for oligomer synthesis |
| SE9502608D0 (sv) | 1995-07-14 | 1995-07-14 | Pharmacia Biosensor Ab | Method for nucleic acid senquencing |
| CA2235762A1 (en) * | 1995-11-14 | 1997-05-22 | Genometrix Genomics, Inc. | Integrated nucleic acid hybridization devices based upon active surface chemistry |
| US6132765A (en) * | 1996-04-12 | 2000-10-17 | Uroteq Inc. | Drug delivery via therapeutic hydrogels |
| US6130037A (en) * | 1996-04-25 | 2000-10-10 | Pence And Mcgill University | Biosensor device and method |
| WO1997041425A1 (en) | 1996-04-25 | 1997-11-06 | Pence, Inc. | Biosensor device and method |
| US6485703B1 (en) * | 1998-07-31 | 2002-11-26 | The Texas A&M University System | Compositions and methods for analyte detection |
| JP3919958B2 (ja) * | 1998-11-11 | 2007-05-30 | 独立行政法人科学技術振興機構 | 高分子薄膜の製造方法 |
| ATE269114T1 (de) * | 1998-11-20 | 2004-07-15 | Univ Connecticut | Verfahren und vorrichtung zur steuerung der gewebeimplantat-interaktionen |
| US6413587B1 (en) * | 1999-03-02 | 2002-07-02 | International Business Machines Corporation | Method for forming polymer brush pattern on a substrate surface |
-
2000
- 2000-01-25 AT AT00909103T patent/ATE334226T1/de not_active IP Right Cessation
- 2000-01-25 US US09/889,935 patent/US7250253B1/en not_active Expired - Fee Related
- 2000-01-25 WO PCT/EP2000/000554 patent/WO2000043539A2/en not_active Ceased
- 2000-01-25 CA CA002360027A patent/CA2360027A1/en not_active Abandoned
- 2000-01-25 JP JP2000594947A patent/JP4970654B2/ja not_active Expired - Fee Related
- 2000-01-25 AU AU31504/00A patent/AU3150400A/en not_active Abandoned
- 2000-01-25 DE DE60029561T patent/DE60029561T2/de not_active Expired - Lifetime
- 2000-01-25 EP EP00909103A patent/EP1144677B1/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| US7250253B1 (en) | 2007-07-31 |
| JP4970654B2 (ja) | 2012-07-11 |
| ATE334226T1 (de) | 2006-08-15 |
| EP1144677A2 (en) | 2001-10-17 |
| EP1144677B1 (en) | 2006-07-26 |
| AU3150400A (en) | 2000-08-07 |
| JP2002535450A (ja) | 2002-10-22 |
| CA2360027A1 (en) | 2000-07-27 |
| WO2000043539A3 (en) | 2000-11-30 |
| WO2000043539A2 (en) | 2000-07-27 |
| DE60029561D1 (de) | 2006-09-07 |
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