DE60000014T2 - Linker-System zum Aktivieren von Oberflächen für die Biokonjugation und Verfahren zu ihrer Verwendung - Google Patents

Linker-System zum Aktivieren von Oberflächen für die Biokonjugation und Verfahren zu ihrer Verwendung

Info

Publication number
DE60000014T2
DE60000014T2 DE60000014T DE60000014T DE60000014T2 DE 60000014 T2 DE60000014 T2 DE 60000014T2 DE 60000014 T DE60000014 T DE 60000014T DE 60000014 T DE60000014 T DE 60000014T DE 60000014 T2 DE60000014 T2 DE 60000014T2
Authority
DE
Germany
Prior art keywords
linker system
bioconjugation
activating surfaces
linker
activating
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60000014T
Other languages
English (en)
Other versions
DE60000014D1 (de
Inventor
Holger Klapproth
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Biochip Technologies GmbH
Original Assignee
Biochip Technologies GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biochip Technologies GmbH filed Critical Biochip Technologies GmbH
Application granted granted Critical
Publication of DE60000014D1 publication Critical patent/DE60000014D1/de
Publication of DE60000014T2 publication Critical patent/DE60000014T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/551—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being inorganic
    • G01N33/552—Glass or silica
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54353—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals with ligand attached to the carrier via a chemical coupling agent

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Inorganic Chemistry (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Treatments Of Macromolecular Shaped Articles (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Pyrrole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE60000014T 2000-05-16 2000-05-16 Linker-System zum Aktivieren von Oberflächen für die Biokonjugation und Verfahren zu ihrer Verwendung Expired - Lifetime DE60000014T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP00110428A EP1132739B1 (de) 2000-05-16 2000-05-16 Linker-System zum Aktivieren von Oberflächen für die Biokonjugation und Verfahren zu ihrer Verwendung

Publications (2)

Publication Number Publication Date
DE60000014D1 DE60000014D1 (de) 2001-11-22
DE60000014T2 true DE60000014T2 (de) 2002-05-02

Family

ID=8168735

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60000014T Expired - Lifetime DE60000014T2 (de) 2000-05-16 2000-05-16 Linker-System zum Aktivieren von Oberflächen für die Biokonjugation und Verfahren zu ihrer Verwendung

Country Status (11)

Country Link
US (1) US6921669B2 (de)
EP (1) EP1132739B1 (de)
JP (1) JP2003533697A (de)
AT (1) ATE206211T1 (de)
AU (1) AU7404201A (de)
CA (1) CA2375160A1 (de)
DE (1) DE60000014T2 (de)
DK (1) DK1132739T3 (de)
ES (1) ES2164632T3 (de)
PT (1) PT1132739E (de)
WO (1) WO2001088535A1 (de)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69737883T2 (de) 1996-04-25 2008-03-06 Bioarray Solutions Ltd. Licht-regulierte, elektrokinetische zusammensetzung von partikeln an oberflächen
US9709559B2 (en) 2000-06-21 2017-07-18 Bioarray Solutions, Ltd. Multianalyte molecular analysis using application-specific random particle arrays
US7262063B2 (en) 2001-06-21 2007-08-28 Bio Array Solutions, Ltd. Directed assembly of functional heterostructures
WO2003091426A1 (en) * 2001-10-12 2003-11-06 Spectral Genomics, Inc. Compilations of nucleic acids and arrays and methods of using them
EP1463825B1 (de) 2001-10-15 2017-12-06 BioArray Solutions Ltd. Gemultiplexte analyse polymorphischer stellen durch gleichzeitige abfrage und enzymvermittelte detektion
US7335153B2 (en) 2001-12-28 2008-02-26 Bio Array Solutions Ltd. Arrays of microparticles and methods of preparation thereof
FR2840324B1 (fr) * 2002-05-28 2005-07-15 Europ Synchrotron Radiation Fa Fabrication de monocouches moleculaires organisees et substrat adapte
AU2003254782A1 (en) * 2002-07-30 2004-04-30 Fujisawa Pharmaceutical Co., Ltd. Method of inhibiting nonspecific interaction between molecules on solid phase support
AU2003298655A1 (en) 2002-11-15 2004-06-15 Bioarray Solutions, Ltd. Analysis, secure access to, and transmission of array images
US7070922B2 (en) * 2002-12-04 2006-07-04 International Business Machines Corporation Surface treatment
US20050059105A1 (en) * 2003-07-25 2005-03-17 Board Of Trustees Of Michigan State University Impedimetric biosensor and its use for rapid detection of bacterial pathogens in solution
WO2005031305A2 (en) 2003-09-22 2005-04-07 Bioarray Solutions, Ltd. Surface immobilized polyelectrolyte with multiple functional groups capable of covalently bonding to biomolecules
CA2899287A1 (en) 2003-10-28 2005-05-12 Bioarray Solutions Ltd. Optimization of gene expression analysis using immobilized capture probes
US7848889B2 (en) 2004-08-02 2010-12-07 Bioarray Solutions, Ltd. Automated analysis of multiplexed probe-target interaction patterns: pattern matching and allele identification
JP2006194796A (ja) * 2005-01-14 2006-07-27 Kyushu Inoac Co Ltd 診断用容器
US20070055013A1 (en) * 2005-02-21 2007-03-08 Noriho Kamiya Substrate and method of immobilizing protein
CN101484151B (zh) 2006-05-05 2012-11-21 密执安州立大学董事会 二价smac模拟物及其应用
KR100819064B1 (ko) 2006-12-19 2008-04-04 (재)대구경북과학기술연구원 생분자 고정화 링커
US9090542B2 (en) 2009-11-11 2015-07-28 University Of Georgia Research Foundation, Inc. Methods for labeling a substrate using a hetero-diels-alder reaction
US20110108411A1 (en) * 2009-11-11 2011-05-12 Popik Vladimir V Methods for labeling a substrate using a hetero-diels-alder reaction
US20150076049A1 (en) * 2012-04-20 2015-03-19 Agency For Science, Technology And Research Microfilter and apparatus for separating a biological entity from a sample volume
WO2013158044A1 (en) * 2012-04-20 2013-10-24 Agency For Science, Technology And Research Apparatus and method for separating a biological entity from a sample volume
JP6733993B2 (ja) 2014-10-03 2020-08-05 シンアフィックス ビー．ブイ． スルファミドリンカー、スルファミドリンカーのコンジュゲート、及び調製の方法
US11590239B2 (en) 2016-02-08 2023-02-28 Synaffix B.V. Antibody-conjugates with improved therapeutic index for targeting CD30 tumours and method for improving therapeutic index of antibody-conjugates
WO2017137457A1 (en) 2016-02-08 2017-08-17 Synaffix B.V. Antibody-conjugates with improved therapeutic index for targeting cd30 tumours and method for improving therapeutic index of antibody-conjugates
US10874746B2 (en) 2016-02-08 2020-12-29 Synaffix B.V. Sulfamide linkers for use in bioconjugates
EP3413916A1 (de) 2016-02-08 2018-12-19 Synaffix B.V. Antikörperkonjugate mit verbessertem therapeutischem index zur abzielung auf cd30-tumoren und verfahren zur verbesserung des therapeutischen index von antikörperkonjugaten
WO2017137456A1 (en) 2016-02-08 2017-08-17 Synaffix B.V. Bioconjugates containing sulfamide linkers for use in treatment
WO2019185586A1 (en) 2018-03-26 2019-10-03 Universidad Complutense De Madrid Ligands for enhanced imaging and drug delivery to neuroblastoma cells

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2707296B1 (fr) * 1993-07-09 1995-09-29 Genset Sa Procédé de synthèse d'acides nucléiques sur support solide et composés utiles notamment comme support solide dans ledit procédé.
JPH08220673A (ja) * 1995-02-17 1996-08-30 Konica Corp ハロゲン化銀写真乳剤及びハロゲン化銀写真要素及びその処理方法
EP0961783B1 (de) * 1997-08-08 2007-01-24 Dade Behring Marburg GmbH Konjugate von polysacchariden und biomolekülen
AU9402198A (en) * 1997-09-26 1999-04-23 Becton Dickinson & Company Preparing conjugates using polyethylene glycol linkers
CA2318371A1 (en) * 1998-01-13 1999-07-22 Biochip Technologies Gmbh Method for the detection of nucleic acid sequences

Also Published As

Publication number Publication date
US20030022189A1 (en) 2003-01-30
ATE206211T1 (de) 2001-10-15
AU7404201A (en) 2001-11-26
PT1132739E (pt) 2002-03-28
CA2375160A1 (en) 2001-11-22
WO2001088535A1 (en) 2001-11-22
EP1132739A1 (de) 2001-09-12
US6921669B2 (en) 2005-07-26
DK1132739T3 (da) 2002-01-28
EP1132739B1 (de) 2001-09-26
DE60000014D1 (de) 2001-11-22
JP2003533697A (ja) 2003-11-11
ES2164632T3 (es) 2002-03-01

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