DE60000014D1 - Linker-System zum Aktivieren von Oberflächen für die Biokonjugation und Verfahren zu ihrer Verwendung - Google Patents

Linker-System zum Aktivieren von Oberflächen für die Biokonjugation und Verfahren zu ihrer Verwendung

Info

Publication number
DE60000014D1
DE60000014D1 DE60000014T DE60000014T DE60000014D1 DE 60000014 D1 DE60000014 D1 DE 60000014D1 DE 60000014 T DE60000014 T DE 60000014T DE 60000014 T DE60000014 T DE 60000014T DE 60000014 D1 DE60000014 D1 DE 60000014D1
Authority
DE
Germany
Prior art keywords
linker system
bioconjugation
activating surfaces
linker
activating
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60000014T
Other languages
English (en)
Other versions
DE60000014T2 (de
Inventor
Holger Klapproth
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Biochip Technologies GmbH
Original Assignee
Biochip Technologies GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biochip Technologies GmbH filed Critical Biochip Technologies GmbH
Application granted granted Critical
Publication of DE60000014D1 publication Critical patent/DE60000014D1/de
Publication of DE60000014T2 publication Critical patent/DE60000014T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/551—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being inorganic
    • G01N33/552—Glass or silica
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54353—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals with ligand attached to the carrier via a chemical coupling agent

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Inorganic Chemistry (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Treatments Of Macromolecular Shaped Articles (AREA)
  • Pyrrole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE60000014T 2000-05-16 2000-05-16 Linker-System zum Aktivieren von Oberflächen für die Biokonjugation und Verfahren zu ihrer Verwendung Expired - Lifetime DE60000014T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP00110428A EP1132739B1 (de) 2000-05-16 2000-05-16 Linker-System zum Aktivieren von Oberflächen für die Biokonjugation und Verfahren zu ihrer Verwendung

Publications (2)

Publication Number Publication Date
DE60000014D1 true DE60000014D1 (de) 2001-11-22
DE60000014T2 DE60000014T2 (de) 2002-05-02

Family

ID=8168735

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60000014T Expired - Lifetime DE60000014T2 (de) 2000-05-16 2000-05-16 Linker-System zum Aktivieren von Oberflächen für die Biokonjugation und Verfahren zu ihrer Verwendung

Country Status (11)

Country Link
US (1) US6921669B2 (de)
EP (1) EP1132739B1 (de)
JP (1) JP2003533697A (de)
AT (1) ATE206211T1 (de)
AU (1) AU7404201A (de)
CA (1) CA2375160A1 (de)
DE (1) DE60000014T2 (de)
DK (1) DK1132739T3 (de)
ES (1) ES2164632T3 (de)
PT (1) PT1132739E (de)
WO (1) WO2001088535A1 (de)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2255599C (en) 1996-04-25 2006-09-05 Bioarray Solutions, Llc Light-controlled electrokinetic assembly of particles near surfaces
US9709559B2 (en) 2000-06-21 2017-07-18 Bioarray Solutions, Ltd. Multianalyte molecular analysis using application-specific random particle arrays
US7262063B2 (en) 2001-06-21 2007-08-28 Bio Array Solutions, Ltd. Directed assembly of functional heterostructures
JP2005519634A (ja) * 2001-10-12 2005-07-07 スペクトラル ジェノミクス、インク． 核酸組成物及びアレイ及びそれらを用いる方法
US20040002073A1 (en) 2001-10-15 2004-01-01 Li Alice Xiang Multiplexed analysis of polymorphic loci by concurrent interrogation and enzyme-mediated detection
US7335153B2 (en) 2001-12-28 2008-02-26 Bio Array Solutions Ltd. Arrays of microparticles and methods of preparation thereof
FR2840324B1 (fr) * 2002-05-28 2005-07-15 Europ Synchrotron Radiation Fa Fabrication de monocouches moleculaires organisees et substrat adapte
WO2004025297A1 (ja) * 2002-07-30 2004-03-25 Reverse Proteomics Research Institute Co., Ltd. 固相担体上における分子間の非特異相互作用の抑制方法
AU2003298655A1 (en) 2002-11-15 2004-06-15 Bioarray Solutions, Ltd. Analysis, secure access to, and transmission of array images
US7070922B2 (en) * 2002-12-04 2006-07-04 International Business Machines Corporation Surface treatment
US20050059105A1 (en) * 2003-07-25 2005-03-17 Board Of Trustees Of Michigan State University Impedimetric biosensor and its use for rapid detection of bacterial pathogens in solution
EP1664722B1 (de) 2003-09-22 2011-11-02 Bioarray Solutions Ltd Oberflächenimmobilisierter polyelektrolyt mit mehreren, zur kovalenten bindung an biomoleküle fähigen funktionellen gruppen
NZ547492A (en) 2003-10-28 2009-12-24 Bioarray Solutions Ltd Optimization of gene expression analysis using immobilized capture probes of different lengths and densities
US7848889B2 (en) 2004-08-02 2010-12-07 Bioarray Solutions, Ltd. Automated analysis of multiplexed probe-target interaction patterns: pattern matching and allele identification
JP2006194796A (ja) * 2005-01-14 2006-07-27 Kyushu Inoac Co Ltd 診断用容器
US20070055013A1 (en) * 2005-02-21 2007-03-08 Noriho Kamiya Substrate and method of immobilizing protein
PT2019671E (pt) 2006-05-05 2014-12-18 Univ Michigan Intermediários para a preparação de miméticos de smac bivalentes
KR100819064B1 (ko) 2006-12-19 2008-04-04 (재)대구경북과학기술연구원 생분자 고정화 링커
US9090542B2 (en) 2009-11-11 2015-07-28 University Of Georgia Research Foundation, Inc. Methods for labeling a substrate using a hetero-diels-alder reaction
US20110108411A1 (en) * 2009-11-11 2011-05-12 Popik Vladimir V Methods for labeling a substrate using a hetero-diels-alder reaction
SG11201406767VA (en) * 2012-04-20 2014-12-30 Agency Science Tech & Res Microfilter and apparatus for separating a biological entity from a sample volume
US20150118728A1 (en) * 2012-04-20 2015-04-30 Agency For Science, Technology And Research Apparatus and method for separating a biological entity from a sample volume
WO2016053107A1 (en) 2014-10-03 2016-04-07 Synaffix B.V. Sulfamide linker, conjugates thereof, and methods of preparation
US10874746B2 (en) 2016-02-08 2020-12-29 Synaffix B.V. Sulfamide linkers for use in bioconjugates
WO2017137457A1 (en) 2016-02-08 2017-08-17 Synaffix B.V. Antibody-conjugates with improved therapeutic index for targeting cd30 tumours and method for improving therapeutic index of antibody-conjugates
EP3413916A1 (de) 2016-02-08 2018-12-19 Synaffix B.V. Antikörperkonjugate mit verbessertem therapeutischem index zur abzielung auf cd30-tumoren und verfahren zur verbesserung des therapeutischen index von antikörperkonjugaten
EP3413915A1 (de) 2016-02-08 2018-12-19 Synaffix B.V. Antikörperkonjugate mit verbessertem therapeutischem index zur abzielung auf her2-tumoren und verfahren zur verbesserung des therapeutischen index von antikörperkonjugaten
JP2019507741A (ja) 2016-02-08 2019-03-22 シンアフィックス ビー．ブイ． 治療において使用するためのスルファミドリンカーを含むバイオコンジュゲート
WO2019185586A1 (en) 2018-03-26 2019-10-03 Universidad Complutense De Madrid Ligands for enhanced imaging and drug delivery to neuroblastoma cells

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2707296B1 (fr) * 1993-07-09 1995-09-29 Genset Sa Procédé de synthèse d'acides nucléiques sur support solide et composés utiles notamment comme support solide dans ledit procédé.
JPH08220673A (ja) * 1995-02-17 1996-08-30 Konica Corp ハロゲン化銀写真乳剤及びハロゲン化銀写真要素及びその処理方法
JP4182269B2 (ja) * 1997-08-08 2008-11-19 ベーリングウエルケ、アクティエンゲゼルシャフト 生体分子のポリサッカライド接合体
AU9402198A (en) * 1997-09-26 1999-04-23 Becton Dickinson & Company Preparing conjugates using polyethylene glycol linkers
EP1047794A2 (de) * 1998-01-13 2000-11-02 BioChip Technologies GmbH Verfahren zum nachweis von nukleinsäuresequenzen

Also Published As

Publication number Publication date
DK1132739T3 (da) 2002-01-28
ES2164632T3 (es) 2002-03-01
EP1132739B1 (de) 2001-09-26
CA2375160A1 (en) 2001-11-22
EP1132739A1 (de) 2001-09-12
PT1132739E (pt) 2002-03-28
AU7404201A (en) 2001-11-26
DE60000014T2 (de) 2002-05-02
US20030022189A1 (en) 2003-01-30
WO2001088535A1 (en) 2001-11-22
ATE206211T1 (de) 2001-10-15
JP2003533697A (ja) 2003-11-11
US6921669B2 (en) 2005-07-26

Similar Documents

Publication Publication Date Title
DE60000014D1 (de) Linker-System zum Aktivieren von Oberflächen für die Biokonjugation und Verfahren zu ihrer Verwendung
ATE351921T1 (de) Verfahren für fluoreszenzerkennungstest
DE69430231T2 (de) Biosensor zum Messen der Alkoholkonzentration, Verfahren zur Herstellung des Biosensors, und den Biosensor benutzendes Betrunkenheitsmessgerät
DE60223635D1 (de) Reagenzien, Verfahren und Vorrichtungen zum Nachweis von Analyten
DE69723860D1 (de) VERFAHREN ZUR BESTIMMUNG VON IgE
ATE438737T1 (de) Verfahren für den nachweis von erkrankungen
ATE540319T1 (de) Verfahren für die bestimmung von fk506
DE60208278D1 (de) System und Verfahren zum Testen von Nukleinsäuremolekülen
DE69710077T2 (de) Verfahren zur erkennung von verbindungen, die die interaktion von rna und rna-bindeproteinen beeinflussen
DE60041355D1 (de) Verfahren zur detektion von erkrankungen
DE69522831T2 (de) Assays und vorrichtungen zum nachweis von extrahepatischer biliäreratresie
ATE373236T1 (de) Puffer-arrays zum nachweis von biomolekülen anhand ihres isoelektrischen punktes
DE69916421D1 (de) Biochip und verfahren zur verwendung des biochips
DE60332382D1 (de) Zentrifugalvorrichtung und verfahren zur durchführung von bindungsversuchen
BR9917198B1 (pt) dispositivo de teste para detecção ou enumeração de microorganismos, e, processo para utilizar um dispositivo de teste.
ATE471989T1 (de) Verfahren zur identifizierung einer auf einen körper aufgebrachten markierung
DE50204680D1 (de) Verfahren zur detektion von nukleinsäuremolekülen
DE69820380D1 (de) Halbleiter-Dehnungs-Sensor, Verfahren zu dessen Herstellung und Rastersondenmikroskop
DE60043618D1 (de) Verfahren zum nachweis einer reaktion zur molekularen erkennung
DE60130970D1 (de) Reagenziensatz zur detektion von mikroorganismen, vorrichtung zur quantifizierungvon mikroorganismen und verfahren zur quantifizierung von mikroorganismen
ATE408832T1 (de) Verfahren zum nachweis von blutzell-antigenen und gegen diese gerichtete antikörper
DE60141790D1 (de) Chromatographische probe und verfahren zu ihrer herstellung
ATE470147T1 (de) Verfahren und mittel zur bestimmung von gesamthärte
DE1218076T1 (de) Verfahren zur reinigung von sequentiellen reaktionsprodukten durch ultrafiltration bei konstantem differentialdruck
ATE340998T1 (de) Verfahren zur bestimmung von flüchtigen substanzen in lösung

Legal Events

Date Code Title Description
8364 No opposition during term of opposition