DE60332382D1 - Zentrifugalvorrichtung und verfahren zur durchführung von bindungsversuchen - Google Patents
Zentrifugalvorrichtung und verfahren zur durchführung von bindungsversuchenInfo
- Publication number
- DE60332382D1 DE60332382D1 DE60332382T DE60332382T DE60332382D1 DE 60332382 D1 DE60332382 D1 DE 60332382D1 DE 60332382 T DE60332382 T DE 60332382T DE 60332382 T DE60332382 T DE 60332382T DE 60332382 D1 DE60332382 D1 DE 60332382D1
- Authority
- DE
- Germany
- Prior art keywords
- carrying
- centrifugal device
- out binding
- binding tests
- relates
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 238000000034 method Methods 0.000 title abstract 2
- 238000000159 protein binding assay Methods 0.000 abstract 2
- 238000003556 assay Methods 0.000 abstract 1
- 230000003993 interaction Effects 0.000 abstract 1
- 239000003446 ligand Substances 0.000 abstract 1
- 238000007899 nucleic acid hybridization Methods 0.000 abstract 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
- G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
- G01N21/64—Fluorescence; Phosphorescence
- G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/508—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
- B01L3/5085—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above for multiple samples, e.g. microtitration plates
- B01L3/50851—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above for multiple samples, e.g. microtitration plates specially adapted for heating or cooling samples
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54366—Apparatus specially adapted for solid-phase testing
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/06—Auxiliary integrated devices, integrated components
- B01L2300/0627—Sensor or part of a sensor is integrated
- B01L2300/0636—Integrated biosensor, microarrays
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0803—Disc shape
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/18—Means for temperature control
- B01L2300/1838—Means for temperature control using fluid heat transfer medium
- B01L2300/1844—Means for temperature control using fluid heat transfer medium using fans
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/18—Means for temperature control
- B01L2300/1861—Means for temperature control using radiation
- B01L2300/1872—Infrared light
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/04—Moving fluids with specific forces or mechanical means
- B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
- B01L2400/0409—Moving fluids with specific forces or mechanical means specific forces centrifugal forces
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L7/00—Heating or cooling apparatus; Heat insulating devices
- B01L7/52—Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Analytical Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Engineering & Computer Science (AREA)
- Physics & Mathematics (AREA)
- Pathology (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Biochemistry (AREA)
- General Physics & Mathematics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Molecular Biology (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Microbiology (AREA)
- Clinical Laboratory Science (AREA)
- Optics & Photonics (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AU2002952797A AU2002952797A0 (en) | 2002-11-20 | 2002-11-20 | Centrifugal device and method using same |
PCT/AU2003/001552 WO2004046719A1 (en) | 2002-11-20 | 2003-11-20 | Centrifugal device and method for performing binding assays |
Publications (1)
Publication Number | Publication Date |
---|---|
DE60332382D1 true DE60332382D1 (de) | 2010-06-10 |
Family
ID=28796174
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60332382T Expired - Lifetime DE60332382D1 (de) | 2002-11-20 | 2003-11-20 | Zentrifugalvorrichtung und verfahren zur durchführung von bindungsversuchen |
Country Status (6)
Country | Link |
---|---|
US (2) | US8080410B2 (de) |
EP (1) | EP1567861B1 (de) |
AT (1) | ATE466283T1 (de) |
AU (1) | AU2002952797A0 (de) |
DE (1) | DE60332382D1 (de) |
WO (1) | WO2004046719A1 (de) |
Families Citing this family (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8491454B2 (en) | 2008-12-02 | 2013-07-23 | President And Fellows Of Harvard College | Spinning force apparatus |
WO2011011823A1 (en) | 2009-07-29 | 2011-02-03 | Pyrobett Pte Ltd | Method and apparatus for conducting an assay |
CN102115712B (zh) * | 2010-12-02 | 2015-05-13 | 广州安必平医药科技股份有限公司 | 核酸分子杂交实验的移液方法及其反应装置 |
JP6430253B2 (ja) | 2011-11-05 | 2018-11-28 | プレジデント アンド フェローズ オブ ハーバード カレッジ | 相互作用を検出および測定するための核酸ベースのリンカー |
MX353148B (es) * | 2012-02-03 | 2017-12-19 | Pyrobett Pte Ltd | Plataforma giratoria para realizar secuenciacion de acidos nucleicos. |
US8597882B2 (en) * | 2012-02-03 | 2013-12-03 | Pyrobett Pte. Ltd. | Method and apparatus for conducting an assay |
AU2012200646B2 (en) * | 2012-02-03 | 2014-09-25 | Pyrobett Pte Ltd. | Method and apparatus for conducting an assay |
US20140072959A1 (en) | 2012-09-12 | 2014-03-13 | Force Diagnostics, Inc. | Rapid tests for insurance underwriting |
US11198900B2 (en) | 2014-12-06 | 2021-12-14 | Children's Medical Center Corporation | Nucleic acid-based linkers for detecting and measuring interactions |
US10948401B2 (en) | 2016-02-25 | 2021-03-16 | President And Fellows Of Harvard College | Spinning apparatus for measurement of characteristics relating to molecules |
US10919037B2 (en) | 2016-03-23 | 2021-02-16 | Children's Medical Center Corporation | Systems and apparatus for detecting compounds in human biological samples |
US11426735B2 (en) | 2016-09-12 | 2022-08-30 | Delta Electronics Int'l (Singapore) Pte Ltd | Nucleic acid analysis apparatus |
US10654038B2 (en) | 2016-09-12 | 2020-05-19 | Delta Electronics Int'l (Singapore) Pte Ltd | Nucleic acid analysis apparatus |
US11478791B2 (en) | 2016-09-12 | 2022-10-25 | Delta Electronics Int'l (Singapore) Pte Ltd | Flow control and processing cartridge |
US10850281B2 (en) | 2016-09-12 | 2020-12-01 | Delta Electronics Int'l (Singapore) Pte Ltd | Nucleic acid analysis apparatus |
US11376581B2 (en) | 2016-09-12 | 2022-07-05 | Delta Electronics Int'l (Singapore) Pte Ltd | Flow control and processing cartridge |
WO2019100080A1 (en) | 2017-11-20 | 2019-05-23 | Children's Medical Center Corporation | Force-controlled nanoswitch assays for single-molecule detection in complex biological fluids |
SG10201900172RA (en) * | 2019-01-08 | 2020-08-28 | Delta Electronics Int’L Singapore Pte Ltd | Multi-color fluorescent excitation and detection device |
Family Cites Families (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3763374A (en) * | 1972-08-22 | 1973-10-02 | Atomic Energy Commission | Dynamic multistation photometer-fluorometer |
WO1995021382A2 (en) * | 1994-02-01 | 1995-08-10 | Fields Robert E | Molecular analyzer and method of use |
US5665558A (en) * | 1994-05-17 | 1997-09-09 | Gamma Biologicals, Inc. | Method and apparatus useful for detecting bloodgroup antigens and antibodies |
JP2002503331A (ja) * | 1995-12-05 | 2002-01-29 | ガメラ バイオサイエンス コーポレイション | 機内に搭載された情報科学を備えた超微量液体素子工学システムにおいて液体移動を推進するために求心性加速を使用するための装置及び方法 |
US20030054376A1 (en) * | 1997-07-07 | 2003-03-20 | Mullis Kary Banks | Dual bead assays using cleavable spacers and/or ligation to improve specificity and sensitivity including related methods and apparatus |
AUPO652997A0 (en) * | 1997-04-30 | 1997-05-29 | Kindconi Pty Limited | Temperature cycling device and method |
CA2309760A1 (en) * | 1997-10-09 | 1999-04-22 | Robert M. Haefele | Modifying double stranded dna to enhance separations by matched ion polynucleotide chromatography |
US6236454B1 (en) * | 1997-12-15 | 2001-05-22 | Applied Materials, Inc. | Multiple beam scanner for an inspection system |
US20020177144A1 (en) * | 1997-12-30 | 2002-11-28 | Jose Remacle | Detection and/or quantification method of a target molecule by a binding with a capture molecule fixed on the surface of a disc |
US6093370A (en) * | 1998-06-11 | 2000-07-25 | Hitachi, Ltd. | Polynucleotide separation method and apparatus therefor |
ATE468175T1 (de) * | 1999-03-25 | 2010-06-15 | Alphahelix Molecular Diagnosti | Homogenisierung von kleinvolumigen mischungen durch zentrifugierung und erhitzen |
US6833250B2 (en) * | 2000-03-06 | 2004-12-21 | Vicam, L.P. | Detection and removal of chitinous material in a biological sample |
WO2001066555A1 (en) * | 2000-03-08 | 2001-09-13 | Datascope Investment Corp. | Methods for assay and detection on a microarray |
US6855553B1 (en) * | 2000-10-02 | 2005-02-15 | 3M Innovative Properties Company | Sample processing apparatus, methods and systems |
US7087203B2 (en) * | 2000-11-17 | 2006-08-08 | Nagaoka & Co., Ltd. | Methods and apparatus for blood typing with optical bio-disc |
WO2002051537A2 (en) * | 2000-12-22 | 2002-07-04 | Burstein Technologies, Inc. | Optical bio-discs and methods relating thereto |
US7141416B2 (en) * | 2001-07-12 | 2006-11-28 | Burstein Technologies, Inc. | Multi-purpose optical analysis optical bio-disc for conducting assays and various reporting agents for use therewith |
-
2002
- 2002-11-20 AU AU2002952797A patent/AU2002952797A0/en not_active Abandoned
-
2003
- 2003-11-20 AT AT03773337T patent/ATE466283T1/de not_active IP Right Cessation
- 2003-11-20 DE DE60332382T patent/DE60332382D1/de not_active Expired - Lifetime
- 2003-11-20 WO PCT/AU2003/001552 patent/WO2004046719A1/en not_active Application Discontinuation
- 2003-11-20 EP EP03773337A patent/EP1567861B1/de not_active Expired - Lifetime
- 2003-11-20 US US10/535,666 patent/US8080410B2/en not_active Expired - Fee Related
-
2011
- 2011-11-15 US US13/296,403 patent/US8338191B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
US8080410B2 (en) | 2011-12-20 |
EP1567861B1 (de) | 2010-04-28 |
EP1567861A1 (de) | 2005-08-31 |
EP1567861A4 (de) | 2008-04-09 |
US8338191B2 (en) | 2012-12-25 |
US20060223061A1 (en) | 2006-10-05 |
AU2002952797A0 (en) | 2002-12-05 |
US20120058008A1 (en) | 2012-03-08 |
ATE466283T1 (de) | 2010-05-15 |
WO2004046719A1 (en) | 2004-06-03 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |