ATE466283T1 - Zentrifugalvorrichtung und verfahren zur durchführung von bindungsversuchen - Google Patents

Zentrifugalvorrichtung und verfahren zur durchführung von bindungsversuchen

Info

Publication number
ATE466283T1
ATE466283T1 AT03773337T AT03773337T ATE466283T1 AT E466283 T1 ATE466283 T1 AT E466283T1 AT 03773337 T AT03773337 T AT 03773337T AT 03773337 T AT03773337 T AT 03773337T AT E466283 T1 ATE466283 T1 AT E466283T1
Authority
AT
Austria
Prior art keywords
centrifugal device
binding tests
conducting binding
relates
assays
Prior art date
Application number
AT03773337T
Other languages
English (en)
Inventor
John Corbett
Original Assignee
Corbett Life Science Pty Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Corbett Life Science Pty Ltd filed Critical Corbett Life Science Pty Ltd
Application granted granted Critical
Publication of ATE466283T1 publication Critical patent/ATE466283T1/de

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/508—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
    • B01L3/5085—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above for multiple samples, e.g. microtitration plates
    • B01L3/50851—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above for multiple samples, e.g. microtitration plates specially adapted for heating or cooling samples
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366—Apparatus specially adapted for solid-phase testing
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/06—Auxiliary integrated devices, integrated components
    • B01L2300/0627—Sensor or part of a sensor is integrated
    • B01L2300/0636—Integrated biosensor, microarrays
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0803—Disc shape
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/18—Means for temperature control
    • B01L2300/1838—Means for temperature control using fluid heat transfer medium
    • B01L2300/1844—Means for temperature control using fluid heat transfer medium using fans
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/18—Means for temperature control
    • B01L2300/1861—Means for temperature control using radiation
    • B01L2300/1872—Infrared light
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0409—Moving fluids with specific forces or mechanical means specific forces centrifugal forces
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L7/00—Heating or cooling apparatus; Heat insulating devices
    • B01L7/52—Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Urology & Nephrology (AREA)
  • Clinical Laboratory Science (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Optics & Photonics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
AT03773337T 2002-11-20 2003-11-20 Zentrifugalvorrichtung und verfahren zur durchführung von bindungsversuchen ATE466283T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AU2002952797A AU2002952797A0 (en) 2002-11-20 2002-11-20 Centrifugal device and method using same
PCT/AU2003/001552 WO2004046719A1 (en) 2002-11-20 2003-11-20 Centrifugal device and method for performing binding assays

Publications (1)

Publication Number Publication Date
ATE466283T1 true ATE466283T1 (de) 2010-05-15

Family

ID=28796174

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03773337T ATE466283T1 (de) 2002-11-20 2003-11-20 Zentrifugalvorrichtung und verfahren zur durchführung von bindungsversuchen

Country Status (6)

Country Link
US (2) US8080410B2 (de)
EP (1) EP1567861B1 (de)
AT (1) ATE466283T1 (de)
AU (1) AU2002952797A0 (de)
DE (1) DE60332382D1 (de)
WO (1) WO2004046719A1 (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8491454B2 (en) 2008-12-02 2013-07-23 President And Fellows Of Harvard College Spinning force apparatus
KR20120089640A (ko) * 2009-07-29 2012-08-13 파이로베트 피티이 엘티디 어세이를 실시하는 방법 및 장치
CN102115712B (zh) * 2010-12-02 2015-05-13 广州安必平医药科技股份有限公司 核酸分子杂交实验的移液方法及其反应装置
JP6430253B2 (ja) 2011-11-05 2018-11-28 プレジデント アンド フェローズ オブ ハーバード カレッジ 相互作用を検出および測定するための核酸ベースのリンカー
JP6047586B2 (ja) * 2012-02-03 2016-12-21 パイロベット ピーティーイー リミテッド 核酸シークエンシングを行うための回転可能なプラットフォーム
US8597882B2 (en) 2012-02-03 2013-12-03 Pyrobett Pte. Ltd. Method and apparatus for conducting an assay
AU2012200646B2 (en) * 2012-02-03 2014-09-25 Pyrobett Pte Ltd. Method and apparatus for conducting an assay
US20140072959A1 (en) 2012-09-12 2014-03-13 Force Diagnostics, Inc. Rapid tests for insurance underwriting
WO2016089588A1 (en) 2014-12-06 2016-06-09 Children's Medical Center Corporation Nucleic acid-based linkers for detecting and measuring interactions
WO2017147398A1 (en) 2016-02-25 2017-08-31 Children's Medical Center Corporation Spinning apparatus for measurement of characteristics relating to molecules
US10919037B2 (en) 2016-03-23 2021-02-16 Children's Medical Center Corporation Systems and apparatus for detecting compounds in human biological samples
US11426735B2 (en) 2016-09-12 2022-08-30 Delta Electronics Int'l (Singapore) Pte Ltd Nucleic acid analysis apparatus
CN107815408B (zh) * 2016-09-12 2021-11-09 台达电子国际（新加坡）私人有限公司 采用等温扩增方式的核酸分析装置
US10850281B2 (en) 2016-09-12 2020-12-01 Delta Electronics Int'l (Singapore) Pte Ltd Nucleic acid analysis apparatus
US11376581B2 (en) 2016-09-12 2022-07-05 Delta Electronics Int'l (Singapore) Pte Ltd Flow control and processing cartridge
US11478791B2 (en) 2016-09-12 2022-10-25 Delta Electronics Int'l (Singapore) Pte Ltd Flow control and processing cartridge
WO2019100080A1 (en) 2017-11-20 2019-05-23 Children's Medical Center Corporation Force-controlled nanoswitch assays for single-molecule detection in complex biological fluids
SG10201900172RA (en) * 2019-01-08 2020-08-28 Delta Electronics Int’L Singapore Pte Ltd Multi-color fluorescent excitation and detection device

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3763374A (en) 1972-08-22 1973-10-02 Atomic Energy Commission Dynamic multistation photometer-fluorometer
ATE265686T1 (de) * 1994-02-01 2004-05-15 Robert E Fields Molekularanalysator und verfahren zu seiner verwendung
US5665558A (en) 1994-05-17 1997-09-09 Gamma Biologicals, Inc. Method and apparatus useful for detecting bloodgroup antigens and antibodies
JP2002503331A (ja) * 1995-12-05 2002-01-29 ガメラ バイオサイエンス コーポレイション 機内に搭載された情報科学を備えた超微量液体素子工学システムにおいて液体移動を推進するために求心性加速を使用するための装置及び方法
US20030054376A1 (en) * 1997-07-07 2003-03-20 Mullis Kary Banks Dual bead assays using cleavable spacers and/or ligation to improve specificity and sensitivity including related methods and apparatus
AUPO652997A0 (en) * 1997-04-30 1997-05-29 Kindconi Pty Limited Temperature cycling device and method
US6210885B1 (en) * 1997-10-09 2001-04-03 Transgenomic, Inc. Modifying double stranded DNA to enhance separations by matched ion polynucleotide chromatography
US6236454B1 (en) * 1997-12-15 2001-05-22 Applied Materials, Inc. Multiple beam scanner for an inspection system
US20020177144A1 (en) * 1997-12-30 2002-11-28 Jose Remacle Detection and/or quantification method of a target molecule by a binding with a capture molecule fixed on the surface of a disc
US6093370A (en) * 1998-06-11 2000-07-25 Hitachi, Ltd. Polynucleotide separation method and apparatus therefor
CA2366732C (en) * 1999-03-25 2008-11-18 Alphahelix Ab Homogenising of small-volume mixtures by centrifugation and heating
US6833250B2 (en) 2000-03-06 2004-12-21 Vicam, L.P. Detection and removal of chitinous material in a biological sample
WO2001066555A1 (en) 2000-03-08 2001-09-13 Datascope Investment Corp. Methods for assay and detection on a microarray
US6855553B1 (en) 2000-10-02 2005-02-15 3M Innovative Properties Company Sample processing apparatus, methods and systems
US7087203B2 (en) * 2000-11-17 2006-08-08 Nagaoka & Co., Ltd. Methods and apparatus for blood typing with optical bio-disc
WO2002051537A2 (en) * 2000-12-22 2002-07-04 Burstein Technologies, Inc. Optical bio-discs and methods relating thereto
US7141416B2 (en) * 2001-07-12 2006-11-28 Burstein Technologies, Inc. Multi-purpose optical analysis optical bio-disc for conducting assays and various reporting agents for use therewith

Also Published As

Publication number Publication date
EP1567861A1 (de) 2005-08-31
WO2004046719A1 (en) 2004-06-03
AU2002952797A0 (en) 2002-12-05
US8338191B2 (en) 2012-12-25
EP1567861A4 (de) 2008-04-09
US20120058008A1 (en) 2012-03-08
US8080410B2 (en) 2011-12-20
EP1567861B1 (de) 2010-04-28
US20060223061A1 (en) 2006-10-05
DE60332382D1 (de) 2010-06-10

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