ATE466283T1 - Zentrifugalvorrichtung und verfahren zur durchführung von bindungsversuchen - Google Patents

Zentrifugalvorrichtung und verfahren zur durchführung von bindungsversuchen

Info

Publication number
ATE466283T1
ATE466283T1 AT03773337T AT03773337T ATE466283T1 AT E466283 T1 ATE466283 T1 AT E466283T1 AT 03773337 T AT03773337 T AT 03773337T AT 03773337 T AT03773337 T AT 03773337T AT E466283 T1 ATE466283 T1 AT E466283T1
Authority
AT
Austria
Prior art keywords
centrifugal device
binding tests
conducting binding
relates
assays
Prior art date
Application number
AT03773337T
Other languages
English (en)
Inventor
John Corbett
Original Assignee
Corbett Life Science Pty Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Corbett Life Science Pty Ltd filed Critical Corbett Life Science Pty Ltd
Application granted granted Critical
Publication of ATE466283T1 publication Critical patent/ATE466283T1/de

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/6428Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/508Rigid containers without fluid transport within
    • B01L3/5085Rigid containers without fluid transport within for multiple samples, e.g. microtitration plates
    • B01L3/50851Rigid containers without fluid transport within for multiple samples, e.g. microtitration plates specially adapted for heating or cooling samples
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54366Apparatus specially adapted for solid-phase testing
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/06Auxiliary integrated devices, integrated components
    • B01L2300/0627Sensor or part of a sensor is integrated
    • B01L2300/0636Integrated biosensor, microarrays
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/08Geometry, shape and general structure
    • B01L2300/0803Disc shape
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/18Means for temperature control
    • B01L2300/1838Means for temperature control using fluid heat transfer medium
    • B01L2300/1844Means for temperature control using fluid heat transfer medium using fans
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00Additional constructional details
    • B01L2300/18Means for temperature control
    • B01L2300/1861Means for temperature control using radiation
    • B01L2300/1872Infrared light
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00Moving or stopping fluids
    • B01L2400/04Moving fluids with specific forces or mechanical means
    • B01L2400/0403Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0409Moving fluids with specific forces or mechanical means specific forces centrifugal forces
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L7/00Heating or cooling apparatus; Heat insulating devices
    • B01L7/52Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Analytical Chemistry (AREA)
  • Urology & Nephrology (AREA)
  • General Physics & Mathematics (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pathology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Optics & Photonics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Clinical Laboratory Science (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
AT03773337T 2002-11-20 2003-11-20 Zentrifugalvorrichtung und verfahren zur durchführung von bindungsversuchen ATE466283T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AU2002952797A AU2002952797A0 (en) 2002-11-20 2002-11-20 Centrifugal device and method using same
PCT/AU2003/001552 WO2004046719A1 (en) 2002-11-20 2003-11-20 Centrifugal device and method for performing binding assays

Publications (1)

Publication Number Publication Date
ATE466283T1 true ATE466283T1 (de) 2010-05-15

Family

ID=28796174

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03773337T ATE466283T1 (de) 2002-11-20 2003-11-20 Zentrifugalvorrichtung und verfahren zur durchführung von bindungsversuchen

Country Status (6)

Country Link
US (2) US8080410B2 (de)
EP (1) EP1567861B1 (de)
AT (1) ATE466283T1 (de)
AU (1) AU2002952797A0 (de)
DE (1) DE60332382D1 (de)
WO (1) WO2004046719A1 (de)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8491454B2 (en) 2008-12-02 2013-07-23 President And Fellows Of Harvard College Spinning force apparatus
MX2012001214A (es) 2009-07-29 2012-06-25 Pyrobett Pte Ltd Metodo y aparato para conducir un ensayo.
CN102115712B (zh) * 2010-12-02 2015-05-13 广州安必平医药科技股份有限公司 核酸分子杂交实验的移液方法及其反应装置
WO2013067489A1 (en) 2011-11-05 2013-05-10 President And Fellows Of Harvard College Nucleic acid-based linkers for detecting and measuring interactions
AU2012200646B2 (en) * 2012-02-03 2014-09-25 Pyrobett Pte Ltd. Method and apparatus for conducting an assay
US8597882B2 (en) * 2012-02-03 2013-12-03 Pyrobett Pte. Ltd. Method and apparatus for conducting an assay
PT2809799T (pt) * 2012-02-03 2017-06-05 Pyrobett Pte Ltd Plataforma giratória para realizar sequenciamento de ácido nucleico
US20140072959A1 (en) 2012-09-12 2014-03-13 Force Diagnostics, Inc. Rapid tests for insurance underwriting
WO2016089588A1 (en) 2014-12-06 2016-06-09 Children's Medical Center Corporation Nucleic acid-based linkers for detecting and measuring interactions
WO2017003950A2 (en) 2015-06-27 2017-01-05 Children's Medical Center Corporation Compositions and methods for analyte detection using nanoswitches
EP3420352B1 (de) 2016-02-25 2023-08-09 Children's Medical Center Corporation Drehvorrichtung zur messung der eigenschaften im zusammenhang mit molekülen
WO2017165585A1 (en) 2016-03-23 2017-09-28 Children's Medical Center Corporation Systems and apparatus for detecting compounds in human biological samples
US10850281B2 (en) 2016-09-12 2020-12-01 Delta Electronics Int'l (Singapore) Pte Ltd Nucleic acid analysis apparatus
US10654038B2 (en) * 2016-09-12 2020-05-19 Delta Electronics Int'l (Singapore) Pte Ltd Nucleic acid analysis apparatus
US11426735B2 (en) 2016-09-12 2022-08-30 Delta Electronics Int'l (Singapore) Pte Ltd Nucleic acid analysis apparatus
US11478791B2 (en) 2016-09-12 2022-10-25 Delta Electronics Int'l (Singapore) Pte Ltd Flow control and processing cartridge
US11376581B2 (en) 2016-09-12 2022-07-05 Delta Electronics Int'l (Singapore) Pte Ltd Flow control and processing cartridge
WO2019100080A1 (en) 2017-11-20 2019-05-23 Children's Medical Center Corporation Force-controlled nanoswitch assays for single-molecule detection in complex biological fluids
SG10201900172RA (en) * 2019-01-08 2020-08-28 Delta Electronics Int’L Singapore Pte Ltd Multi-color fluorescent excitation and detection device

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3763374A (en) * 1972-08-22 1973-10-02 Atomic Energy Commission Dynamic multistation photometer-fluorometer
ATE265686T1 (de) * 1994-02-01 2004-05-15 Robert E Fields Molekularanalysator und verfahren zu seiner verwendung
US5665558A (en) * 1994-05-17 1997-09-09 Gamma Biologicals, Inc. Method and apparatus useful for detecting bloodgroup antigens and antibodies
KR100306951B1 (ko) * 1995-12-05 2001-11-15 테칸 보스턴, 인코포레이티드 내장된정보과학에의해미세유체공학시스템내의유체유동을구동시키기위해구심가속도를이용하는장치및방법
US20030054376A1 (en) * 1997-07-07 2003-03-20 Mullis Kary Banks Dual bead assays using cleavable spacers and/or ligation to improve specificity and sensitivity including related methods and apparatus
AUPO652997A0 (en) * 1997-04-30 1997-05-29 Kindconi Pty Limited Temperature cycling device and method
AU752932B2 (en) * 1997-10-09 2002-10-03 Transgenomic, Inc. Modifying double stranded DNA to enhance separations by matched ion polynucleotide chromatography
US6236454B1 (en) * 1997-12-15 2001-05-22 Applied Materials, Inc. Multiple beam scanner for an inspection system
US20020177144A1 (en) * 1997-12-30 2002-11-28 Jose Remacle Detection and/or quantification method of a target molecule by a binding with a capture molecule fixed on the surface of a disc
US6093370A (en) * 1998-06-11 2000-07-25 Hitachi, Ltd. Polynucleotide separation method and apparatus therefor
CA2366732C (en) * 1999-03-25 2008-11-18 Alphahelix Ab Homogenising of small-volume mixtures by centrifugation and heating
US6833250B2 (en) 2000-03-06 2004-12-21 Vicam, L.P. Detection and removal of chitinous material in a biological sample
AU2001247328C1 (en) 2000-03-08 2006-10-26 Datascope Investment Corp. Methods for assay and detection on a microarray
US6855553B1 (en) 2000-10-02 2005-02-15 3M Innovative Properties Company Sample processing apparatus, methods and systems
US7087203B2 (en) * 2000-11-17 2006-08-08 Nagaoka & Co., Ltd. Methods and apparatus for blood typing with optical bio-disc
US20020168652A1 (en) * 2000-12-22 2002-11-14 Werner Martina Elisabeth Surface assembly for immobilizing DNA capture probes and bead-based assay including optical bio-discs and methods relating thereto
US7141416B2 (en) * 2001-07-12 2006-11-28 Burstein Technologies, Inc. Multi-purpose optical analysis optical bio-disc for conducting assays and various reporting agents for use therewith

Also Published As

Publication number Publication date
US20060223061A1 (en) 2006-10-05
DE60332382D1 (de) 2010-06-10
AU2002952797A0 (en) 2002-12-05
EP1567861A4 (de) 2008-04-09
WO2004046719A1 (en) 2004-06-03
US8338191B2 (en) 2012-12-25
US20120058008A1 (en) 2012-03-08
EP1567861A1 (de) 2005-08-31
US8080410B2 (en) 2011-12-20
EP1567861B1 (de) 2010-04-28

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