ATE489482T1 - Verfahren zur herstellung von hybridsubstraten mit dna und antikörpern sowie verwendungen davon - Google Patents
Verfahren zur herstellung von hybridsubstraten mit dna und antikörpern sowie verwendungen davonInfo
- Publication number
- ATE489482T1 ATE489482T1 AT06801832T AT06801832T ATE489482T1 AT E489482 T1 ATE489482 T1 AT E489482T1 AT 06801832 T AT06801832 T AT 06801832T AT 06801832 T AT06801832 T AT 06801832T AT E489482 T1 ATE489482 T1 AT E489482T1
- Authority
- AT
- Austria
- Prior art keywords
- antibodies
- capture probes
- capture
- bound
- dna
- Prior art date
Links
- 239000000758 substrate Substances 0.000 title abstract 6
- 238000004519 manufacturing process Methods 0.000 title 1
- 239000000523 sample Substances 0.000 abstract 9
- 108091034117 Oligonucleotide Proteins 0.000 abstract 3
- JLCPHMBAVCMARE-UHFFFAOYSA-N [3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-hydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methyl [5-(6-aminopurin-9-yl)-2-(hydroxymethyl)oxolan-3-yl] hydrogen phosphate Polymers Cc1cn(C2CC(OP(O)(=O)OCC3OC(CC3OP(O)(=O)OCC3OC(CC3O)n3cnc4c3nc(N)[nH]c4=O)n3cnc4c3nc(N)[nH]c4=O)C(COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3CO)n3cnc4c(N)ncnc34)n3ccc(N)nc3=O)n3cnc4c(N)ncnc34)n3ccc(N)nc3=O)n3ccc(N)nc3=O)n3ccc(N)nc3=O)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cc(C)c(=O)[nH]c3=O)n3cc(C)c(=O)[nH]c3=O)n3ccc(N)nc3=O)n3cc(C)c(=O)[nH]c3=O)n3cnc4c3nc(N)[nH]c4=O)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)O2)c(=O)[nH]c1=O JLCPHMBAVCMARE-UHFFFAOYSA-N 0.000 abstract 3
- 108091023037 Aptamer Proteins 0.000 abstract 2
- 239000012491 analyte Substances 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6813—Hybridisation assays
- C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54366—Apparatus specially adapted for solid-phase testing
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54366—Apparatus specially adapted for solid-phase testing
- G01N33/54386—Analytical elements
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/0054—Means for coding or tagging the apparatus or the reagents
- B01J2219/00547—Bar codes
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/0054—Means for coding or tagging the apparatus or the reagents
- B01J2219/00572—Chemical means
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
- B01J2219/0061—The surface being organic
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
- B01J2219/00612—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports the surface being inorganic
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00605—Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
- B01J2219/00632—Introduction of reactive groups to the surface
- B01J2219/00637—Introduction of reactive groups to the surface by coating it with another layer
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00639—Making arrays on substantially continuous surfaces the compounds being trapped in or bound to a porous medium
- B01J2219/00641—Making arrays on substantially continuous surfaces the compounds being trapped in or bound to a porous medium the porous medium being continuous, e.g. porous oxide substrates
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00583—Features relative to the processes being carried out
- B01J2219/00603—Making arrays on substantially continuous surfaces
- B01J2219/00659—Two-dimensional arrays
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/0068—Means for controlling the apparatus of the process
- B01J2219/00702—Processes involving means for analysing and characterising the products
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00718—Type of compounds synthesised
- B01J2219/0072—Organic compounds
- B01J2219/00722—Nucleotides
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00718—Type of compounds synthesised
- B01J2219/0072—Organic compounds
- B01J2219/00725—Peptides
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Physics & Mathematics (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Analytical Chemistry (AREA)
- Organic Chemistry (AREA)
- Biochemistry (AREA)
- Cell Biology (AREA)
- General Physics & Mathematics (AREA)
- Nanotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Food Science & Technology (AREA)
- Biophysics (AREA)
- General Engineering & Computer Science (AREA)
- Pathology (AREA)
- Medical Informatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Crystallography & Structural Chemistry (AREA)
- Genetics & Genomics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US70961305P | 2005-08-19 | 2005-08-19 | |
| PCT/US2006/032301 WO2007024676A2 (en) | 2005-08-19 | 2006-08-18 | Methods for preparing hybrid substrates comprising dna and antibodies and uses thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE489482T1 true ATE489482T1 (de) | 2010-12-15 |
Family
ID=37533338
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT06801832T ATE489482T1 (de) | 2005-08-19 | 2006-08-18 | Verfahren zur herstellung von hybridsubstraten mit dna und antikörpern sowie verwendungen davon |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20090111094A1 (de) |
| EP (1) | EP1915466B1 (de) |
| JP (1) | JP2009505106A (de) |
| AT (1) | ATE489482T1 (de) |
| DE (1) | DE602006018477D1 (de) |
| WO (1) | WO2007024676A2 (de) |
Families Citing this family (38)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES3045958T3 (en) * | 2007-07-17 | 2025-12-01 | Somalogic Operating Co Inc | Method for generating aptamers with improved off-rates |
| US8852893B2 (en) * | 2007-09-14 | 2014-10-07 | Physicians Choice Laboratory Services, Llc | Detection of nucleic acids and proteins |
| JP2009085619A (ja) * | 2007-09-27 | 2009-04-23 | Tdk Corp | バイオセンサ |
| JP2010099061A (ja) * | 2008-09-26 | 2010-05-06 | Sekisui Chem Co Ltd | 検出用カートリッジ及び被検出物質の検出方法 |
| EP2389585A2 (de) * | 2009-01-22 | 2011-11-30 | Li-Cor, Inc. | Einzelmolekül-proteomik mit dynamischen sonden |
| JP5626673B2 (ja) * | 2009-03-12 | 2014-11-19 | 国立大学法人東京農工大学 | ジンクフィンガーを用いた新規標識方法及び被検物質の測定方法 |
| CN101967517B (zh) * | 2010-03-19 | 2012-11-07 | 黄乐群 | 一种无需借助pcr的基因检测方法 |
| WO2012004790A2 (en) * | 2010-07-06 | 2012-01-12 | Aptateck Bio Ltd. | Nucleic acid aptamer-based diagnostic methods with novel techniques for signal enhancement |
| CN102147414B (zh) * | 2010-12-30 | 2013-07-03 | 中国科学院上海微系统与信息技术研究所 | 基于纳米探针的微流体芯片检测微量蛋白的方法 |
| EP3225697A3 (de) | 2010-12-30 | 2017-11-22 | Foundation Medicine, Inc. | Optimierung von multigenanalysen von tumorproben |
| CN102520189A (zh) * | 2011-12-16 | 2012-06-27 | 首都医科大学 | 一个基于纳米技术的psa高敏感检测方法 |
| JP5566543B2 (ja) | 2012-03-30 | 2014-08-06 | 国立大学法人九州大学 | センサ、検出方法、検出システム、及び、検出装置 |
| KR101460439B1 (ko) | 2012-05-14 | 2014-11-12 | 서울대학교산학협력단 | 나노프로브 및 이를 이용한 표적 물질 검출방법 |
| WO2013184788A1 (en) * | 2012-06-05 | 2013-12-12 | Predictive Biosciences, Inc. | Detection of nucleic acids and proteins |
| WO2014007034A1 (ja) * | 2012-07-06 | 2014-01-09 | 株式会社 日立ハイテクノロジーズ | 分析装置及び分析方法 |
| KR101470730B1 (ko) * | 2013-04-24 | 2014-12-09 | 경희대학교 산학협력단 | 파장-의존성 플라즈몬 공명산란을 이용한 나노바이오칩 키트 및 이를 이용한 생체분자의 검출방법 |
| CN104458710B (zh) * | 2014-12-09 | 2017-11-14 | 山东省海盟生化科技有限公司 | 肿瘤早期高通量电化学发光检测方法的构建 |
| AU2016270823B2 (en) | 2015-06-01 | 2020-09-03 | California Institute Of Technology | Compositions and methods for screening T cells with antigens for specific populations |
| WO2017007847A1 (en) * | 2015-07-07 | 2017-01-12 | The Regents Of The University Of California | Method for detecting protein-specific glycosylation |
| CN105132533B (zh) * | 2015-07-24 | 2018-11-23 | 清华大学深圳研究生院 | 一种靶分子浓度的检测方法 |
| CN110050071A (zh) | 2016-12-09 | 2019-07-23 | 乌尔蒂维尤股份有限公司 | 用于使用标记的核酸成像剂进行多路复用成像的改进方法 |
| EP3592862A1 (de) | 2017-03-08 | 2020-01-15 | California Institute of Technology | Paarung der antigenspezifität einer t-zelle mit t-zell-rezeptor-sequenzen |
| CN110446719B (zh) * | 2017-03-31 | 2023-10-03 | 乌尔蒂维尤股份有限公司 | Dna-抗原交换和扩增 |
| KR20210035167A (ko) | 2018-06-11 | 2021-03-31 | 파운데이션 메디신 인코포레이티드 | 게놈 변경을 평가하기 위한 조성물 및 방법 |
| AU2020235929A1 (en) * | 2019-03-13 | 2021-09-23 | Evorion Biotechnologies Gmbh | Methods and kits for determining cell secreted biomolecules |
| EP3963070A4 (de) * | 2019-04-30 | 2023-02-22 | Encodia, Inc. | Verfahren zur herstellung von analyten und zugehörige kits |
| EP3974844A4 (de) * | 2019-05-21 | 2022-08-03 | Toppan Inc. | Verfahren zum nachweis eines zielmoleküls |
| CN110361433B (zh) * | 2019-07-04 | 2021-09-24 | 章毅 | 电化学检测细胞的方法及其组合物 |
| US20240353401A1 (en) * | 2020-08-18 | 2024-10-24 | Unicornfish Pty Ltd As Trustee For Rcx Unit Trust | Compositions and methods for detecting SARS-CoV-2 spike protein |
| WO2022058557A1 (en) * | 2020-09-17 | 2022-03-24 | Evorion Biotechnologies Gmbh | Method for analyzing cell released biomolecules |
| JP7610736B2 (ja) * | 2021-06-17 | 2025-01-08 | エフ． ホフマン－ラ ロシュ アーゲー | 磁気トンネル接合部を使用して脂質層上で免疫センシングするための方法ｉｉ |
| CN117501122A (zh) * | 2021-06-17 | 2024-02-02 | 豪夫迈·罗氏有限公司 | 用于使用磁性隧道结对脂质层进行免疫传感的方法 |
| EP4356132B1 (de) * | 2021-06-17 | 2025-10-01 | F. Hoffmann-La Roche AG | Verfahren zum immunosensing auf einer lipidschicht |
| US20230203595A1 (en) * | 2021-11-11 | 2023-06-29 | Korea University Research And Business Foundation | Surface-enhanced raman scattering (sers) biosensor for diagnosing prostate cancer with high sensitivity |
| KR102864797B1 (ko) * | 2021-11-11 | 2025-09-25 | 고려대학교 산학협력단 | 고감도 전립선암 진단용 표면-증강 라만 산란(sers) 바이오센서 |
| CN114199816B (zh) * | 2021-11-22 | 2023-11-03 | 湖北大学 | 基于近红外光激发检测生物标志物的光热传感器及其制备方法、在标志物检测中的应用 |
| GB2639519A (en) * | 2023-10-26 | 2025-10-01 | Todd Daniel | Nanites: smart, programmable polymer composite nucleic-acid nanostructures for sensitive, targeted, molecular nucleic acid detection |
| CN117871873A (zh) * | 2024-02-18 | 2024-04-12 | 河南省科学院物理研究所 | 一种基于高分子微球的显微暗场生物检测方法 |
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-
2006
- 2006-08-18 EP EP06801832A patent/EP1915466B1/de not_active Expired - Lifetime
- 2006-08-18 AT AT06801832T patent/ATE489482T1/de not_active IP Right Cessation
- 2006-08-18 WO PCT/US2006/032301 patent/WO2007024676A2/en not_active Ceased
- 2006-08-18 DE DE602006018477T patent/DE602006018477D1/de not_active Expired - Lifetime
- 2006-08-18 US US11/506,280 patent/US20090111094A1/en not_active Abandoned
- 2006-08-18 JP JP2008527164A patent/JP2009505106A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| JP2009505106A (ja) | 2009-02-05 |
| WO2007024676A2 (en) | 2007-03-01 |
| EP1915466A2 (de) | 2008-04-30 |
| EP1915466B1 (de) | 2010-11-24 |
| US20090111094A1 (en) | 2009-04-30 |
| WO2007024676A3 (en) | 2007-06-07 |
| DE602006018477D1 (de) | 2011-01-05 |
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