DE602006016326D1 - Kompakte vorrichtung, zusammensetzungen und verfahren zur reinigung von nukleinsäuren - Google Patents

Kompakte vorrichtung, zusammensetzungen und verfahren zur reinigung von nukleinsäuren

Info

Publication number
DE602006016326D1
DE602006016326D1 DE602006016326T DE602006016326T DE602006016326D1 DE 602006016326 D1 DE602006016326 D1 DE 602006016326D1 DE 602006016326 T DE602006016326 T DE 602006016326T DE 602006016326 T DE602006016326 T DE 602006016326T DE 602006016326 D1 DE602006016326 D1 DE 602006016326D1
Authority
DE
Germany
Prior art keywords
compositions
nucleic acids
compact device
cleaning
cleaning nucleic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE602006016326T
Other languages
English (en)
Inventor
Tim Quinn
Alan Wirbisky
Der Lught Nick Van
Nate Morken
Rebecca Johnson
Kim Paulsen
Dan Strom
Jim Baldrica
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Qiagen North American Holdings Inc
Original Assignee
Qiagen North American Holdings Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Qiagen North American Holdings Inc filed Critical Qiagen North American Holdings Inc
Publication of DE602006016326D1 publication Critical patent/DE602006016326D1/de
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00Sampling; Preparing specimens for investigation
    • G01N1/28Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
    • G01N1/34Purifying; Cleaning
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/06Lysis of microorganisms
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/10Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1003Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor
    • C12N15/1006Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor by means of a solid support carrier, e.g. particles, polymers
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/10Processes for the isolation, preparation or purification of DNA or RNA
    • C12N15/1003Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor
    • C12N15/1006Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor by means of a solid support carrier, e.g. particles, polymers
    • C12N15/1013Extracting or separating nucleic acids from biological samples, e.g. pure separation or isolation methods; Conditions, buffers or apparatuses therefor by means of a solid support carrier, e.g. particles, polymers by using magnetic beads
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/0098Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor involving analyte bound to insoluble magnetic carrier, e.g. using magnetic separation

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Medicinal Chemistry (AREA)
  • Mycology (AREA)
  • Virology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Saccharide Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Detergent Compositions (AREA)
DE602006016326T 2005-10-21 2006-10-16 Kompakte vorrichtung, zusammensetzungen und verfahren zur reinigung von nukleinsäuren Active DE602006016326D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11/255,807 US20070092403A1 (en) 2005-10-21 2005-10-21 Compact apparatus, compositions and methods for purifying nucleic acids
PCT/US2006/040173 WO2007050327A2 (en) 2005-10-21 2006-10-16 Compact apparatus, compositions and methods for purifying nucleic acids

Publications (1)

Publication Number Publication Date
DE602006016326D1 true DE602006016326D1 (de) 2010-09-30

Family

ID=37836740

Family Applications (1)

Application Number Title Priority Date Filing Date
DE602006016326T Active DE602006016326D1 (de) 2005-10-21 2006-10-16 Kompakte vorrichtung, zusammensetzungen und verfahren zur reinigung von nukleinsäuren

Country Status (6)

Country Link
US (2) US20070092403A1 (de)
EP (1) EP1955079B1 (de)
JP (1) JP2009512445A (de)
AT (1) ATE478342T1 (de)
DE (1) DE602006016326D1 (de)
WO (1) WO2007050327A2 (de)

Families Citing this family (73)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6692700B2 (en) 2001-02-14 2004-02-17 Handylab, Inc. Heat-reduction methods and systems related to microfluidic devices
US7829025B2 (en) 2001-03-28 2010-11-09 Venture Lending & Leasing Iv, Inc. Systems and methods for thermal actuation of microfluidic devices
US6852287B2 (en) 2001-09-12 2005-02-08 Handylab, Inc. Microfluidic devices having a reduced number of input and output connections
US7010391B2 (en) 2001-03-28 2006-03-07 Handylab, Inc. Methods and systems for control of microfluidic devices
US8895311B1 (en) 2001-03-28 2014-11-25 Handylab, Inc. Methods and systems for control of general purpose microfluidic devices
US7893228B2 (en) * 2001-10-12 2011-02-22 Qiagen North American Holdings, Inc. Compositions and methods for using a solid support to purify RNA
US20050032105A1 (en) * 2001-10-12 2005-02-10 Bair Robert Jackson Compositions and methods for using a solid support to purify DNA
US7148343B2 (en) * 2001-10-12 2006-12-12 Gentra Systems, Inc. Compositions and methods for using a solid support to purify RNA
GB0208642D0 (en) 2002-04-16 2002-05-22 Accentus Plc Metal implants
JP4996248B2 (ja) 2003-07-31 2012-08-08 ハンディーラブ インコーポレイテッド 粒子含有サンプルの処理
GB0405680D0 (en) 2004-03-13 2004-04-21 Accentus Plc Metal implants
US8852862B2 (en) 2004-05-03 2014-10-07 Handylab, Inc. Method for processing polynucleotide-containing samples
KR20130143677A (ko) 2004-11-05 2013-12-31 퀴아젠 노쓰 아메리칸 홀딩즈, 인크. 안정화 시약으로부터 핵산을 정제하기 위한 조성물 및 방법
DK3088083T3 (en) 2006-03-24 2018-11-26 Handylab Inc Method of carrying out PCR down a multi-track cartridge
US10900066B2 (en) 2006-03-24 2021-01-26 Handylab, Inc. Microfluidic system for amplifying and detecting polynucleotides in parallel
US7998708B2 (en) * 2006-03-24 2011-08-16 Handylab, Inc. Microfluidic system for amplifying and detecting polynucleotides in parallel
US11806718B2 (en) 2006-03-24 2023-11-07 Handylab, Inc. Fluorescence detector for microfluidic diagnostic system
WO2008060604A2 (en) 2006-11-14 2008-05-22 Handylab, Inc. Microfluidic system for amplifying and detecting polynucleotides in parallel
WO2008061165A2 (en) 2006-11-14 2008-05-22 Handylab, Inc. Microfluidic cartridge and method of making same
US20080131500A1 (en) * 2006-12-04 2008-06-05 The Board Of Regents Of The University Of Texas System Methods and compositions for rapid inactivation of proteins
EP1947463A1 (de) * 2007-01-16 2008-07-23 Roche Diagnostics GmbH Entnahme von flüssigen Analyseproben zum Zweck der klinischen Analyse
ES2665280T3 (es) * 2007-06-29 2018-04-25 Becton, Dickinson And Company Métodos para la extracción y purificación de componentes de muestras biológicas
US9186677B2 (en) 2007-07-13 2015-11-17 Handylab, Inc. Integrated apparatus for performing nucleic acid extraction and diagnostic testing on multiple biological samples
US8133671B2 (en) 2007-07-13 2012-03-13 Handylab, Inc. Integrated apparatus for performing nucleic acid extraction and diagnostic testing on multiple biological samples
US8287820B2 (en) 2007-07-13 2012-10-16 Handylab, Inc. Automated pipetting apparatus having a combined liquid pump and pipette head system
EP3741869A1 (de) 2007-07-13 2020-11-25 Handylab, Inc. Materialien zur erfassung von polynukleotiden und verfahren zur verwendung davon
US8182763B2 (en) 2007-07-13 2012-05-22 Handylab, Inc. Rack for sample tubes and reagent holders
US9618139B2 (en) 2007-07-13 2017-04-11 Handylab, Inc. Integrated heater and magnetic separator
US8105783B2 (en) 2007-07-13 2012-01-31 Handylab, Inc. Microfluidic cartridge
KR101443218B1 (ko) * 2007-08-16 2014-09-24 삼성전자주식회사 코스모트로픽 염을 이용한 고체 지지체에서의 rna 정제방법
US20090053704A1 (en) * 2007-08-24 2009-02-26 Natalia Novoradovskaya Stabilization of nucleic acids on solid supports
JP5287861B2 (ja) 2007-10-03 2013-09-11 アクセンタス メディカル リミテッド 殺生物特性を持つ金属の製造方法
KR101432034B1 (ko) * 2007-11-16 2014-08-21 삼성전자주식회사 코스모트로픽 염을 이용한 고체 지지체에서의 작은 rna분리 방법
EP2281826B1 (de) * 2008-04-02 2016-02-17 Rbc Bioscience Corp. Auf magnetischen cellulosematerialien basierende reagentien, chaotrope mittel, kits und methoden zur isolierung von nukleinsäuren
US20110009608A1 (en) * 2008-04-09 2011-01-13 Bioneer Corporation Automatic refining apparatus, multi-well plate kit and method for extracting hexane from biological samples
KR101025135B1 (ko) 2008-04-09 2011-03-31 (주)바이오니아 자동정제장치, 멀티 웰 플레이트 키트 및 생물학적 시료로부터 핵산을 추출하는 방법
USD787087S1 (en) 2008-07-14 2017-05-16 Handylab, Inc. Housing
CN102099607B (zh) * 2008-07-18 2015-05-27 芙罗服务管理公司 可变速致动器
US10094485B2 (en) 2008-07-18 2018-10-09 Flowserve Management Company Variable-speed actuator
WO2010088517A1 (en) * 2009-01-30 2010-08-05 The U.S.A., As Represented By The Secretary, Department Of Health And Human Services Methods and systems for purifying transferring and/or manipulating nucleic acids
JP2013523143A (ja) * 2010-04-08 2013-06-17 キアゲン ゲーエムベーハー 核酸を単離および精製するための方法
JP2013528786A (ja) 2010-04-08 2013-07-11 キアゲン ゲーエムベーハー 核酸を単離および精製するためのクロマトグラフィーデバイスおよび方法
EP2395082A1 (de) 2010-06-14 2011-12-14 QIAGEN GmbH Extraktion von Nukleinsäuren aus in Wachs eingebetteten Proben
KR101400675B1 (ko) 2010-11-18 2014-05-29 (주)바이오니아 에어로졸방지를 위한 자동정제장비 및 자동정제방법
SG193283A1 (en) 2011-03-03 2013-10-30 Life Technologies Corp Sampling probes, systems, apparatuses, and methods
BR112013026451B1 (pt) 2011-04-15 2021-02-09 Becton, Dickinson And Company sistema e método para realizar ensaios de diagnóstico molecular em várias amostras em paralelo e simultaneamente amplificação em tempo real em pluralidade de câmaras de reação de amplificação
BR112013032629A2 (pt) 2011-06-19 2017-08-01 Abogen Inc dispositivos, soluções e métodos para coletamento de amostra
USD692162S1 (en) 2011-09-30 2013-10-22 Becton, Dickinson And Company Single piece reagent holder
AU2012315595B2 (en) 2011-09-30 2015-10-22 Becton, Dickinson And Company Unitized reagent strip
CN104040238B (zh) 2011-11-04 2017-06-27 汉迪拉布公司 多核苷酸样品制备装置
CN102514874B (zh) * 2011-12-29 2013-09-25 协鑫动力新材料(盐城)有限公司 一种组合式电池转移装置
CA2863637C (en) 2012-02-03 2021-10-26 Becton, Dickinson And Company External files for distribution of molecular diagnostic tests and determination of compatibility between tests
CN103013814B (zh) * 2012-12-20 2014-07-02 嘉兴凯实生物科技有限公司 一种核酸纯化装置
CN105592925B (zh) * 2013-05-24 2019-01-11 澳康姆生物实验室公司 用于收集核酸的样品的系统和方法
US11046949B2 (en) 2014-04-10 2021-06-29 Dna Genotek Inc. Method and system for microbial lysis using periodates
CN110488029B (zh) * 2014-06-17 2024-01-16 深圳迈瑞生物医疗电子股份有限公司 提取物分离装置及其工作方法
WO2016081860A1 (en) 2014-11-21 2016-05-26 Occam Biolabs, Inc. System and method for collecting a sample of nucleic acid
WO2016210420A1 (en) 2015-06-26 2016-12-29 Abbott Laboratories Reaction vessel exchanger device for a diagnostic analyzer
JP6771903B2 (ja) * 2016-02-29 2020-10-21 シスメックス株式会社 検体前処理装置、検体前処理カートリッジおよび検体前処理方法
EP3213819B1 (de) * 2016-03-02 2021-09-29 F. Hoffmann-La Roche AG Vorrichtung und methode zur trennung
CN107345199A (zh) * 2016-05-05 2017-11-14 王磊 生物样品制备系统
KR102256775B1 (ko) 2016-09-29 2021-05-27 (주)바이오니아 생물학적 시료 처리장치
JP7089299B2 (ja) 2017-07-21 2022-06-22 シージーン アイエヌシー 磁性モジュール及びカバーモジュールを用いた核酸抽出方法、磁性モジュール、カバーモジュール、部品、並びに自動化システム
EP3679350A4 (de) * 2017-09-05 2021-10-20 George Mismas Probenvorbereitungsvorrichtung
EP3470141B1 (de) * 2017-10-11 2024-04-24 F. Hoffmann-La Roche AG Vorrichtung und verfahren zur verarbeitung einer biologischen probe mit magnetischen partikeln
KR102066119B1 (ko) * 2018-02-09 2020-02-17 제노플랜코리아 주식회사 다중 분석을 수행하기 위한 분주 매핑 장치 및 그 동작 방법
WO2020005584A1 (en) * 2018-06-28 2020-01-02 Gen-Probe Incorporated Sample preparation method and system
CN111100860A (zh) * 2018-10-26 2020-05-05 南京金斯瑞生物科技有限公司 一种大规模磁力纯化系统
CN110819623A (zh) * 2019-11-08 2020-02-21 珠海迪尔生物工程有限公司 核酸提取仪及提取方法
CN110699429B (zh) * 2019-11-25 2023-04-07 宁波艾捷康宁生物科技有限公司 一种尿液dna提取保存液、尿液保存管、提取试剂盒和提取方法
WO2021119241A1 (en) * 2019-12-13 2021-06-17 Becton, Dickinson And Company Magnet assembly to prevent extraction particle carryover
CN111172240A (zh) * 2020-03-06 2020-05-19 苏州博方生物技术有限公司 一种核酸释放剂及hpv病毒核酸检测试剂盒
CN112834298B (zh) * 2020-12-30 2022-01-28 山西大学 一种防污染样本处理系统

Family Cites Families (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS56119254A (en) * 1980-02-25 1981-09-18 Takeda Chemical Industries Ltd Rubber stopper for vial
US4508625A (en) * 1982-10-18 1985-04-02 Graham Marshall D Magnetic separation using chelated magnetic ions
US5523231A (en) * 1990-02-13 1996-06-04 Amersham International Plc Method to isolate macromolecules using magnetically attractable beads which do not specifically bind the macromolecules
DE69126690T2 (de) * 1990-04-06 1998-01-02 Perkin Elmer Corp Automatisiertes labor für molekularbiologie
DK74692D0 (da) * 1992-06-03 1992-06-03 Foss Electric As Apparat
US5364790A (en) * 1993-02-16 1994-11-15 The Perkin-Elmer Corporation In situ PCR amplification system
US5342581A (en) * 1993-04-19 1994-08-30 Sanadi Ashok R Apparatus for preventing cross-contamination of multi-well test plates
US6258325B1 (en) * 1993-04-19 2001-07-10 Ashok Ramesh Sanadi Method and apparatus for preventing cross-contamination of multi-well test plates
US20030127396A1 (en) * 1995-02-21 2003-07-10 Siddiqi Iqbal Waheed Apparatus and method for processing magnetic particles
US6143250A (en) * 1995-07-31 2000-11-07 Precision System Science Co., Ltd. Multi-vessel container for testing fluids
JP3927570B2 (ja) * 1995-07-31 2007-06-13 プレシジョン・システム・サイエンス株式会社 容器
US5973137A (en) * 1996-02-13 1999-10-26 Gentra Systems, Inc. Low pH RNA isolation reagents, method, and kit
US5863801A (en) * 1996-06-14 1999-01-26 Sarnoff Corporation Automated nucleic acid isolation
US5885529A (en) * 1996-06-28 1999-03-23 Dpc Cirrus, Inc. Automated immunoassay analyzer
WO1998001760A2 (en) * 1996-07-05 1998-01-15 Beckman Coulter, Inc. Automated sample processing system
US5990302A (en) * 1996-07-12 1999-11-23 Toyo Boseki Kabushiki Kaisha Method for isolating ribonucleic acid
US6027945A (en) * 1997-01-21 2000-02-22 Promega Corporation Methods of isolating biological target materials using silica magnetic particles
EP1027145A4 (de) * 1997-09-17 2004-08-25 Gentra Systems Inc Vorrichtung und verfahren zur isolierung von nukleinsäure
EP1075328B1 (de) * 1998-05-01 2005-11-16 Gen-Probe Incorporated Automatisiertes diagnostisches analyseverfahren
DE19856064C2 (de) * 1998-12-04 2000-11-30 Invitek Gmbh Universelles Verfahren zur Isolierung von DNA aus beliebigen Ausgangsmaterialien
US6716396B1 (en) * 1999-05-14 2004-04-06 Gen-Probe Incorporated Penetrable cap
NL1012996C2 (nl) * 1999-09-08 2001-03-12 Micronic B V Afsluitmat voor het afsluiten van reageerbuizen.
US6455005B1 (en) * 2000-02-02 2002-09-24 Soltec, Inc. Flexible septa closure plug mats for well plate mounted arrays of sample vials
US6672458B2 (en) * 2000-05-19 2004-01-06 Becton, Dickinson And Company System and method for manipulating magnetically responsive particles fluid samples to collect DNA or RNA from a sample
EP1283865A4 (de) * 2000-05-26 2004-10-06 Whatman Inc Verwendung von membranabdeckung in der prävention von kreuz-kontamination im multiplen prozessieren während der isolierung von biologischem material
GB0013658D0 (en) * 2000-06-05 2000-07-26 Dynal Asa Nucleic acid isolation
US7070740B1 (en) * 2000-09-28 2006-07-04 Beckman Coulter, Inc. Method and apparatus for processing biomolecule arrays
DE10063984A1 (de) * 2000-12-19 2002-06-20 Bilatec Ges Zur Entwicklung Bi Vorrichtungen zur magnetischen Abtrennung von Magnetpartikeln
DE60231265D1 (de) * 2001-03-09 2009-04-02 Gen Probe Inc Verfahren zum Entnehmen von Flüssigkeit aus einem Behälter mit durchdringbarem Verschluss
US6739478B2 (en) * 2001-06-29 2004-05-25 Scientific Products & Systems Llc Precision fluid dispensing system
JP3979996B2 (ja) * 2001-10-12 2007-09-19 ジェントラ システムズ インコーポレイテッド 固体支持体を使用してrnaを精製するための組成物および方法
US7148343B2 (en) * 2001-10-12 2006-12-12 Gentra Systems, Inc. Compositions and methods for using a solid support to purify RNA
US20050032105A1 (en) * 2001-10-12 2005-02-10 Bair Robert Jackson Compositions and methods for using a solid support to purify DNA
US7893228B2 (en) * 2001-10-12 2011-02-22 Qiagen North American Holdings, Inc. Compositions and methods for using a solid support to purify RNA
EP1487969A4 (de) * 2001-12-07 2008-07-09 Dyax Corp Verfahren und vorrichtung zum waschen von magnetisch reagierenden teilchen
US20040197780A1 (en) * 2003-04-02 2004-10-07 Agencourt Bioscience Corporation Method for isolating nucleic acids
US20050009036A1 (en) * 2003-07-11 2005-01-13 Applera Corporation Methods and kits for obtaining nucleic acid from biological samples
EP1664295A4 (de) * 2003-09-09 2007-12-05 Fujifilm Corp Verfahren zur isolierung und reinigung einer nukleinsäure
JP4284250B2 (ja) * 2003-09-09 2009-06-24 富士フイルム株式会社 核酸分離精製方法
DE602004026912D1 (de) * 2003-12-16 2010-06-10 Qiagen North American Holdings Formulierungen und verfahren zum denaturieren von proteinen
JP2005272397A (ja) * 2004-03-25 2005-10-06 Fuji Photo Film Co Ltd 核酸の分離精製方法
KR20130143677A (ko) * 2004-11-05 2013-12-31 퀴아젠 노쓰 아메리칸 홀딩즈, 인크. 안정화 시약으로부터 핵산을 정제하기 위한 조성물 및 방법

Also Published As

Publication number Publication date
US20120058011A1 (en) 2012-03-08
US20070092403A1 (en) 2007-04-26
WO2007050327A2 (en) 2007-05-03
JP2009512445A (ja) 2009-03-26
EP1955079B1 (de) 2010-08-18
WO2007050327A3 (en) 2007-08-09
EP1955079A2 (de) 2008-08-13
ATE478342T1 (de) 2010-09-15

Similar Documents

Publication Publication Date Title
DE602006016326D1 (de) Kompakte vorrichtung, zusammensetzungen und verfahren zur reinigung von nukleinsäuren
DE602005001156D1 (de) Verfahren und vorrichtung zur reinigung von nukleinsäuren
DE602005027144D1 (de) Vorrichtung und Verfahren zur PCR-Amplifizierungsreaktion
ATE524944T1 (de) Verfahren und vorrichtung zur übermittlung von rückstandsinformationen
ATE540114T1 (de) Verfahren und zusammensetzungen zur schnellen isolierung kleiner rna-moleküle
DE602004029853D1 (de) Vorrichtung und Verfahren zur Aufbereitung von Proben
DE502005006617D1 (de) Verfahren und vorrichtung zur bewertung von fahrsituationen
DE602005022123D1 (de) Vorrichtung und verfahren zur beförderung von bohrklein
DE60234540D1 (de) Verfahren zum nachweis von nukleinsäure mittels dna-mikroarrays und vorrichtung zum nukleinsäurenachweis
DE60334148D1 (de) Verfahren zur schnellen forensischenanalyse mitochondrialer dna und charakterisierung der heteroplasmiemitochondrialer dna
DE602004030850D1 (de) Vorrichtung und Verfahren zur Trennung und Reinigung von Nucleinsäuren
DE602006013585D1 (de) Vorrichtung und Verfahren zur Vermeidung von Flugzeugkollisionen (TCAS)
DE602006001379D1 (de) Vorrichtung und Verfahren zur Erfassung von Verschiebungen
DE602004021522D1 (de) Verfahren zur Entnahme von Mikroorganismen und Vorrichtung zur Entnahme von Mikroorganismen
DE602004020605D1 (de) Verfahren und vorrichtung zur entfernung von organ
DE112004003144A5 (de) Verfahren und Vorrichtung zur Massenspektrometrie
ATE515498T1 (de) Verfahren zur aufreinigung von montelukast und dessen aminsalzen
ATE337855T1 (de) Verfahren und vorrichtung zur vorbehandlung von proben durch zentrifugieren
DE602006000332D1 (de) Verfahren und Vorrichtung zur Verbesserung von doppelpolarisierten optischen Übertragungsleistung
ATE527037T1 (de) Ein chromatographisches quasi-kontinuierliches verfahren und entsprechende vorrichtung zur trennung von binären und mehrstoffgemischen
ATE510029T1 (de) Verfahren zur analyse von nukleinsäuren
DE60332382D1 (de) Zentrifugalvorrichtung und verfahren zur durchführung von bindungsversuchen
DE602004002888D1 (de) Vorrichtung und Verfahren zum Sanieren und Entsalzen von biologischen Proben
DE602005022658D1 (de) Verfahren und Gerät zur Analyse von Nukleinsäure-Amplifikation
DE602005007263D1 (de) Werkzeuge und verfahren zur quantifizierung von dna-wiederholungssequenzen