DE69532953T8 - Molekularanalysator und verfahren zu seiner verwendung - Google Patents

Molekularanalysator und verfahren zu seiner verwendung Download PDF

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Publication number
DE69532953T8
DE69532953T8 DE69532953T DE69532953T DE69532953T8 DE 69532953 T8 DE69532953 T8 DE 69532953T8 DE 69532953 T DE69532953 T DE 69532953T DE 69532953 T DE69532953 T DE 69532953T DE 69532953 T8 DE69532953 T8 DE 69532953T8
Authority
DE
Germany
Prior art keywords
molecules
sample
test sample
target
detection reagents
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69532953T
Other languages
English (en)
Other versions
DE69532953T2 (de
DE69532953D1 (de
Inventor
Robert E. Fields
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Igene inc (ndgesdstaates Delaware) Menlo Par
Original Assignee
Igene inc (ndgesdstaates Delaware)
Igene Inc (ndgesdstaates Delaware) Menlo Park
IGENE Inc N D GES D STAATES DE
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB9401849A external-priority patent/GB9401849D0/en
Priority claimed from GB9402357A external-priority patent/GB9402357D0/en
Priority claimed from GB9404758A external-priority patent/GB9404758D0/en
Priority claimed from GB9413641A external-priority patent/GB9413641D0/en
Application filed by Igene inc (ndgesdstaates Delaware), Igene Inc (ndgesdstaates Delaware) Menlo Park, IGENE Inc N D GES D STAATES DE filed Critical Igene inc (ndgesdstaates Delaware)
Application granted granted Critical
Publication of DE69532953D1 publication Critical patent/DE69532953D1/de
Publication of DE69532953T2 publication Critical patent/DE69532953T2/de
Publication of DE69532953T8 publication Critical patent/DE69532953T8/de
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L7/00Heating or cooling apparatus; Heat insulating devices
    • B01L7/52Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L9/00Supporting devices; Holding devices
    • B01L9/06Test-tube stands; Test-tube holders
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N2035/00178Special arrangements of analysers
    • G01N2035/00237Handling microquantities of analyte, e.g. microvalves, capillary networks
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/6428Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/76Chemiluminescence; Bioluminescence
    • G01N21/763Bioluminescence

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Molecular Biology (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
DE69532953T 1994-02-01 1995-02-01 Molekularanalysator und verfahren zu seiner verwendung Expired - Fee Related DE69532953T8 (de)

Applications Claiming Priority (13)

Application Number Priority Date Filing Date Title
GB9401849 1994-02-01
GB9401849A GB9401849D0 (en) 1994-02-01 1994-02-01 Reaction-chamber cassette
GB9402357 1994-02-08
GB9402357A GB9402357D0 (en) 1994-02-08 1994-02-08 Sample processor
GB9404758A GB9404758D0 (en) 1994-03-11 1994-03-11 PCR workstation
GB9404758 1994-03-11
GB9405565 1994-03-21
GB9405565A GB9405565D0 (en) 1994-02-08 1994-03-21 Capillary tube holder and method of use
GB9413641 1994-07-06
GB9413641A GB9413641D0 (en) 1994-07-06 1994-07-06 Tube holder and dispenser
GB9421378 1994-10-24
GB9421378A GB9421378D0 (en) 1994-02-01 1994-10-24 Molecular analyzer and method of use
PCT/US1995/001591 WO1995021382A2 (en) 1994-02-01 1995-02-01 Molecular analyzer and method of use

Publications (3)

Publication Number Publication Date
DE69532953D1 DE69532953D1 (de) 2004-06-03
DE69532953T2 DE69532953T2 (de) 2005-06-02
DE69532953T8 true DE69532953T8 (de) 2005-10-06

Family

ID=27547213

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69532953T Expired - Fee Related DE69532953T8 (de) 1994-02-01 1995-02-01 Molekularanalysator und verfahren zu seiner verwendung

Country Status (7)

Country Link
EP (1) EP0752105B1 (de)
JP (1) JP3383310B2 (de)
AT (1) ATE265686T1 (de)
AU (1) AU699986B2 (de)
CA (1) CA2182513A1 (de)
DE (1) DE69532953T8 (de)
WO (1) WO1995021382A2 (de)

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US5935522A (en) * 1990-06-04 1999-08-10 University Of Utah Research Foundation On-line DNA analysis system with rapid thermal cycling
US7081226B1 (en) 1996-06-04 2006-07-25 University Of Utah Research Foundation System and method for fluorescence monitoring
US7273749B1 (en) 1990-06-04 2007-09-25 University Of Utah Research Foundation Container for carrying out and monitoring biological processes
US5976896A (en) * 1994-06-06 1999-11-02 Idexx Laboratories, Inc. Immunoassays in capillary tubes
US5830657A (en) * 1996-05-01 1998-11-03 Visible Genetics Inc. Method for single-tube sequencing of nucleic acid polymers
WO1997035181A1 (en) * 1996-03-19 1997-09-25 University Of Utah Research Foundation System for determining analyte concentration
US7244622B2 (en) 1996-04-03 2007-07-17 Applera Corporation Device and method for multiple analyte detection
JP4912517B2 (ja) * 1996-04-03 2012-04-11 アプライド バイオシステムズ リミテッド ライアビリティー カンパニー 複数の分析物の検出のためのデバイスおよび方法
US7235406B1 (en) 1996-04-03 2007-06-26 Applera Corporation Nucleic acid analysis device
US6825047B1 (en) 1996-04-03 2004-11-30 Applera Corporation Device and method for multiple analyte detection
CA2252571A1 (en) * 1996-05-01 1997-11-06 Visible Genetics Inc. Method and apparatus for thermal cycling and for automated sample preparation with thermal cycling
ATE295427T1 (de) 1996-06-04 2005-05-15 Univ Utah Res Found Überwachung der hybridisierung während pcr
JP4281877B2 (ja) * 1996-06-04 2009-06-17 ユニバーシティ オブ ユタ リサーチ ファウンデーション 生物学的プロセスを実行し且つモニタリングするためのシステムと方法
US6143496A (en) 1997-04-17 2000-11-07 Cytonix Corporation Method of sampling, amplifying and quantifying segment of nucleic acid, polymerase chain reaction assembly having nanoliter-sized sample chambers, and method of filling assembly
US6025189A (en) * 1997-05-14 2000-02-15 3M Innovative Properties Company Apparatus for reading a plurality of biological indicators
US6037186A (en) 1997-07-16 2000-03-14 Stimpson; Don Parallel production of high density arrays
GB9719673D0 (en) * 1997-09-17 1997-11-19 Glaxo Group Ltd Novel apparatus
US6210882B1 (en) 1998-01-29 2001-04-03 Mayo Foundation For Medical Education And Reseach Rapid thermocycling for sample analysis
US8337753B2 (en) 1998-05-01 2012-12-25 Gen-Probe Incorporated Temperature-controlled incubator having a receptacle mixing mechanism
EP1930078A1 (de) 1998-05-01 2008-06-11 Gen-Probe Incorporated Verfahren zum Umrühren des Inhalts eines Containers
GB2403536B (en) * 2002-04-23 2006-11-08 Idaho Technology Inc Sample withdrawal and dispensing device
AU2003283064B2 (en) * 2002-11-20 2009-06-04 Qiagen Gmbh Centrifugal device and method for performing binding assays
AU2002952797A0 (en) * 2002-11-20 2002-12-05 Bio-Molecular Holdings Pty Limited Centrifugal device and method using same
WO2004059312A1 (en) * 2002-12-20 2004-07-15 Corning Incorporated Capillary assay device and method
FR2938063B1 (fr) * 2008-11-05 2014-09-19 Commissariat Energie Atomique Dispositif de preparation et/ou de traitement d'un echantillon biologique
US8196479B2 (en) * 2009-10-20 2012-06-12 Midwest Research Institute, Inc. Portable multi-tube air sampler unit
CN102200536B (zh) 2010-03-25 2015-05-27 艾博生物医药(杭州)有限公司 测试液体样本中被分析物的检测装置
CN103675303B (zh) 2010-07-23 2016-02-03 贝克曼考尔特公司 传感器系统
US9482684B2 (en) 2011-11-07 2016-11-01 Beckman Coulter, Inc. Centrifuge system and workflow
EP2776846B1 (de) 2011-11-07 2019-08-21 Beckman Coulter, Inc. Aliquotierungssystem und arbeitsablauf
ES2778054T3 (es) 2011-11-07 2020-08-07 Beckman Coulter Inc Sistema y método para transportar recipientes de muestras
JP2014532881A (ja) 2011-11-07 2014-12-08 ベックマン コールター, インコーポレイテッド 標本輸送システムのための磁気制動
EP2776844B1 (de) 2011-11-07 2020-09-30 Beckman Coulter, Inc. Probenbehälterdetektion
US9446418B2 (en) 2011-11-07 2016-09-20 Beckman Coulter, Inc. Robotic arm
JP2013230117A (ja) * 2012-04-27 2013-11-14 Yokohama National Univ 加熱冷却装置及びそれを用いた加熱冷却方法
GB201615320D0 (en) * 2016-09-09 2016-10-26 Invitron Ltd Point of care platform test
CN112368077B (zh) * 2018-12-07 2023-11-24 元素生物科学公司 流动池装置及其用途

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CS178550B1 (en) * 1974-08-21 1977-10-31 Mirko Deml Isotachophoretic column
US4747919A (en) * 1987-01-16 1988-05-31 Large Scale Biology Corporation Apparatus and method for electrophoresis in tubes
WO1992020778A1 (en) * 1991-05-24 1992-11-26 Kindconi Pty Limited Biochemical reaction control

Also Published As

Publication number Publication date
EP0752105A1 (de) 1997-01-08
AU1745495A (en) 1995-08-21
WO1995021382A2 (en) 1995-08-10
DE69532953T2 (de) 2005-06-02
WO1995021382A3 (en) 1995-11-09
ATE265686T1 (de) 2004-05-15
EP0752105B1 (de) 2004-04-28
JPH09511572A (ja) 1997-11-18
CA2182513A1 (en) 1995-08-10
JP3383310B2 (ja) 2003-03-04
AU699986B2 (en) 1998-12-17
DE69532953D1 (de) 2004-06-03

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Legal Events

Date Code Title Description
8327 Change in the person/name/address of the patent owner

Owner name: IGENE,INC. (N.D.GES.D.STAATES DELAWARE), MENLO PAR

8381 Inventor (new situation)

Inventor name: FIELDS, ROBERT E., MENLO PARK, US

8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee