DE69532953D1 - Molekularanalysator und verfahren zu seiner verwendung - Google Patents

Molekularanalysator und verfahren zu seiner verwendung

Info

Publication number
DE69532953D1
DE69532953D1 DE69532953T DE69532953T DE69532953D1 DE 69532953 D1 DE69532953 D1 DE 69532953D1 DE 69532953 T DE69532953 T DE 69532953T DE 69532953 T DE69532953 T DE 69532953T DE 69532953 D1 DE69532953 D1 DE 69532953D1
Authority
DE
Germany
Prior art keywords
molecules
sample
test sample
target
detection reagents
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69532953T
Other languages
English (en)
Other versions
DE69532953T8 (de
DE69532953T2 (de
Inventor
Robert E Fields
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
IGENE,INC. (N.D.GES.D.STAATES DELAWARE), MENLO PAR
Original Assignee
Robert E Fields
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB9401849A external-priority patent/GB9401849D0/en
Priority claimed from GB9402357A external-priority patent/GB9402357D0/en
Priority claimed from GB9404758A external-priority patent/GB9404758D0/en
Priority claimed from GB9413641A external-priority patent/GB9413641D0/en
Application filed by Robert E Fields filed Critical Robert E Fields
Publication of DE69532953D1 publication Critical patent/DE69532953D1/de
Application granted granted Critical
Publication of DE69532953T2 publication Critical patent/DE69532953T2/de
Publication of DE69532953T8 publication Critical patent/DE69532953T8/de
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L7/00—Heating or cooling apparatus; Heat insulating devices
    • B01L7/52—Heating or cooling apparatus; Heat insulating devices with provision for submitting samples to a predetermined sequence of different temperatures, e.g. for treating nucleic acid samples
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L9/00—Supporting devices; Holding devices
    • B01L9/06—Test-tube stands; Test-tube holders
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N2035/00178—Special arrangements of analysers
    • G01N2035/00237—Handling microquantities of analyte, e.g. microvalves, capillary networks
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63—Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64—Fluorescence; Phosphorescence
    • G01N21/6428—Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
    • G01N21/76—Chemiluminescence; Bioluminescence
    • G01N21/763—Bioluminescence

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hematology (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
DE69532953T 1994-02-01 1995-02-01 Molekularanalysator und verfahren zu seiner verwendung Expired - Fee Related DE69532953T8 (de)

Applications Claiming Priority (13)

Application Number Priority Date Filing Date Title
GB9401849A GB9401849D0 (en) 1994-02-01 1994-02-01 Reaction-chamber cassette
GB9401849 1994-02-01
GB9402357A GB9402357D0 (en) 1994-02-08 1994-02-08 Sample processor
GB9402357 1994-02-08
GB9404758 1994-03-11
GB9404758A GB9404758D0 (en) 1994-03-11 1994-03-11 PCR workstation
GB9405565A GB9405565D0 (en) 1994-02-08 1994-03-21 Capillary tube holder and method of use
GB9405565 1994-03-21
GB9413641A GB9413641D0 (en) 1994-07-06 1994-07-06 Tube holder and dispenser
GB9413641 1994-07-06
GB9421378 1994-10-24
GB9421378A GB9421378D0 (en) 1994-02-01 1994-10-24 Molecular analyzer and method of use
PCT/US1995/001591 WO1995021382A2 (en) 1994-02-01 1995-02-01 Molecular analyzer and method of use

Publications (3)

Publication Number Publication Date
DE69532953D1 true DE69532953D1 (de) 2004-06-03
DE69532953T2 DE69532953T2 (de) 2005-06-02
DE69532953T8 DE69532953T8 (de) 2005-10-06

Family

ID=27547213

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69532953T Expired - Fee Related DE69532953T8 (de) 1994-02-01 1995-02-01 Molekularanalysator und verfahren zu seiner verwendung

Country Status (7)

Country Link
EP (1) EP0752105B1 (de)
JP (1) JP3383310B2 (de)
AT (1) ATE265686T1 (de)
AU (1) AU699986B2 (de)
CA (1) CA2182513A1 (de)
DE (1) DE69532953T8 (de)
WO (1) WO1995021382A2 (de)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5935522A (en) * 1990-06-04 1999-08-10 University Of Utah Research Foundation On-line DNA analysis system with rapid thermal cycling
US7081226B1 (en) 1996-06-04 2006-07-25 University Of Utah Research Foundation System and method for fluorescence monitoring
US7273749B1 (en) 1990-06-04 2007-09-25 University Of Utah Research Foundation Container for carrying out and monitoring biological processes
US5976896A (en) * 1994-06-06 1999-11-02 Idexx Laboratories, Inc. Immunoassays in capillary tubes
US5830657A (en) * 1996-05-01 1998-11-03 Visible Genetics Inc. Method for single-tube sequencing of nucleic acid polymers
US6287871B1 (en) * 1996-03-19 2001-09-11 University Of Utah Research Foundation System for determining analyte concentration
WO1997036681A1 (en) * 1996-04-03 1997-10-09 The Perkin-Elmer Corporation Device and method for multiple analyte detection
US7235406B1 (en) 1996-04-03 2007-06-26 Applera Corporation Nucleic acid analysis device
US7244622B2 (en) 1996-04-03 2007-07-17 Applera Corporation Device and method for multiple analyte detection
US6825047B1 (en) 1996-04-03 2004-11-30 Applera Corporation Device and method for multiple analyte detection
CA2252571A1 (en) * 1996-05-01 1997-11-06 Visible Genetics Inc. Method and apparatus for thermal cycling and for automated sample preparation with thermal cycling
ATE390491T1 (de) * 1996-06-04 2008-04-15 Univ Utah Res Found Behälter zum durchführen und beobachten biologischer prozesse
NZ502323A (en) 1996-06-04 2001-09-28 Univ Utah Res Found Monitoring a fluorescence energy transfer pair during hybridization of first probe labelled with fluorescein to second probe labelled with Cy5 or Cy5.5
US6143496A (en) 1997-04-17 2000-11-07 Cytonix Corporation Method of sampling, amplifying and quantifying segment of nucleic acid, polymerase chain reaction assembly having nanoliter-sized sample chambers, and method of filling assembly
US6025189A (en) * 1997-05-14 2000-02-15 3M Innovative Properties Company Apparatus for reading a plurality of biological indicators
US6037186A (en) 1997-07-16 2000-03-14 Stimpson; Don Parallel production of high density arrays
GB9719673D0 (en) * 1997-09-17 1997-11-19 Glaxo Group Ltd Novel apparatus
US6210882B1 (en) 1998-01-29 2001-04-03 Mayo Foundation For Medical Education And Reseach Rapid thermocycling for sample analysis
ATE369915T1 (de) * 1998-05-01 2007-09-15 Gen Probe Inc Inkubator für automatische analysevorrichtung
US8337753B2 (en) 1998-05-01 2012-12-25 Gen-Probe Incorporated Temperature-controlled incubator having a receptacle mixing mechanism
US8409508B2 (en) 2002-04-23 2013-04-02 Biofire Diagnostics, Inc. Sample withdrawal and dispensing device
AU2003283064B2 (en) * 2002-11-20 2009-06-04 Qiagen Gmbh Centrifugal device and method for performing binding assays
AU2002952797A0 (en) * 2002-11-20 2002-12-05 Bio-Molecular Holdings Pty Limited Centrifugal device and method using same
US7110107B2 (en) * 2002-12-20 2006-09-19 Corning Incorporated Capillary assay device and method
FR2938063B1 (fr) * 2008-11-05 2014-09-19 Commissariat Energie Atomique Dispositif de preparation et/ou de traitement d'un echantillon biologique
US8196479B2 (en) * 2009-10-20 2012-06-12 Midwest Research Institute, Inc. Portable multi-tube air sampler unit
CN102200536B (zh) * 2010-03-25 2015-05-27 艾博生物医药(杭州)有限公司 测试液体样本中被分析物的检测装置
CN103675303B (zh) 2010-07-23 2016-02-03 贝克曼考尔特公司 传感器系统
WO2013070755A2 (en) 2011-11-07 2013-05-16 Beckman Coulter, Inc. Centrifuge system and workflow
BR112014011048A2 (pt) 2011-11-07 2017-05-02 Beckman Coulter Inc braço robótico
BR112014011043A2 (pt) 2011-11-07 2017-06-13 Beckman Coulter Inc detecção de recipiente de espécime
EP2776848B1 (de) 2011-11-07 2019-12-25 Beckman Coulter, Inc. System und verfahren zum transport von probenbehältern
EP3373015A1 (de) 2011-11-07 2018-09-12 Beckman Coulter Inc. Aliquotierungssystem und arbeitsablauf
JP2014532881A (ja) 2011-11-07 2014-12-08 ベックマン コールター， インコーポレイテッド 標本輸送システムのための磁気制動
JP2013230117A (ja) * 2012-04-27 2013-11-14 Yokohama National Univ 加熱冷却装置及びそれを用いた加熱冷却方法
GB201615320D0 (en) * 2016-09-09 2016-10-26 Invitron Ltd Point of care platform test
AU2019392932B2 (en) * 2018-12-07 2023-11-02 Element Biosciences, Inc. Flow cell device and use thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CS178550B1 (en) * 1974-08-21 1977-10-31 Mirko Deml Isotachophoretic column
US4747919A (en) * 1987-01-16 1988-05-31 Large Scale Biology Corporation Apparatus and method for electrophoresis in tubes
WO1992020778A1 (en) * 1991-05-24 1992-11-26 Kindconi Pty Limited Biochemical reaction control

Also Published As

Publication number Publication date
WO1995021382A3 (en) 1995-11-09
JPH09511572A (ja) 1997-11-18
CA2182513A1 (en) 1995-08-10
DE69532953T8 (de) 2005-10-06
EP0752105B1 (de) 2004-04-28
WO1995021382A2 (en) 1995-08-10
AU699986B2 (en) 1998-12-17
EP0752105A1 (de) 1997-01-08
AU1745495A (en) 1995-08-21
JP3383310B2 (ja) 2003-03-04
ATE265686T1 (de) 2004-05-15
DE69532953T2 (de) 2005-06-02

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Legal Events

Date Code Title Description
8327 Change in the person/name/address of the patent owner

Owner name: IGENE,INC. (N.D.GES.D.STAATES DELAWARE), MENLO PAR

8381 Inventor (new situation)

Inventor name: FIELDS, ROBERT E., MENLO PARK, US

8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee