ATE373236T1 - Puffer-arrays zum nachweis von biomolekülen anhand ihres isoelektrischen punktes - Google Patents
Puffer-arrays zum nachweis von biomolekülen anhand ihres isoelektrischen punktesInfo
- Publication number
- ATE373236T1 ATE373236T1 AT02756507T AT02756507T ATE373236T1 AT E373236 T1 ATE373236 T1 AT E373236T1 AT 02756507 T AT02756507 T AT 02756507T AT 02756507 T AT02756507 T AT 02756507T AT E373236 T1 ATE373236 T1 AT E373236T1
- Authority
- AT
- Austria
- Prior art keywords
- isoelectric point
- arrays
- detecting biomolecules
- buffer arrays
- buffer
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/416—Systems
- G01N27/447—Systems using electrophoresis
- G01N27/44756—Apparatus specially adapted therefor
- G01N27/44795—Isoelectric focusing
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/416—Systems
- G01N27/447—Systems using electrophoresis
- G01N27/44704—Details; Accessories
- G01N27/44747—Composition of gel or of carrier mixture
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Analytical Chemistry (AREA)
- Pathology (AREA)
- Electrochemistry (AREA)
- Physics & Mathematics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Dispersion Chemistry (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US30580201P | 2001-07-16 | 2001-07-16 | |
US31031601P | 2001-08-06 | 2001-08-06 | |
US34069801P | 2001-10-29 | 2001-10-29 | |
US37704402P | 2002-04-30 | 2002-04-30 |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE373236T1 true ATE373236T1 (de) | 2007-09-15 |
Family
ID=27501888
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT02756507T ATE373236T1 (de) | 2001-07-16 | 2002-07-16 | Puffer-arrays zum nachweis von biomolekülen anhand ihres isoelektrischen punktes |
Country Status (12)
Country | Link |
---|---|
US (2) | US7166202B2 (de) |
EP (1) | EP1410029B1 (de) |
JP (1) | JP4108037B2 (de) |
CN (1) | CN1549924A (de) |
AT (1) | ATE373236T1 (de) |
AU (1) | AU2002322513B2 (de) |
BR (1) | BR0211213A (de) |
CA (1) | CA2454045A1 (de) |
DE (1) | DE60222427T2 (de) |
DK (1) | DK1410029T3 (de) |
IL (1) | IL159810A0 (de) |
WO (1) | WO2003008977A2 (de) |
Families Citing this family (38)
Publication number | Priority date | Publication date | Assignee | Title |
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JP4108037B2 (ja) * | 2001-07-16 | 2008-06-25 | プロテイン, フォレスト, インコーポレイテッド | 生体分子の等電点によって生体分子を分析するためのバッファのアレイ |
US7622028B2 (en) | 2003-05-09 | 2009-11-24 | Life Technologies Corporation | Solution phase electrophoresis device, components, and methods |
WO2004104548A2 (en) | 2003-05-09 | 2004-12-02 | Invitrogen Corporation | Solution phase electrophoresis device, components, and methods |
WO2005021841A2 (en) | 2003-09-03 | 2005-03-10 | Bioforms | Methods and apparatus for rapid crystallization of biomolecules |
EP1668350B1 (de) * | 2003-09-24 | 2012-06-13 | Agilent Technologies, Inc. | Elektroforetische trennung von amphoterischen molekülen |
EP1685395A2 (de) * | 2003-11-05 | 2006-08-02 | EXACT Sciences Corporation | Repetitive umkehrfeld-affinitätselektrophorese und verwendungen dafür |
WO2005089910A1 (en) * | 2004-03-17 | 2005-09-29 | Ciphergen Biosystems, Inc. | Multi-compartment filter and method of filtering using same |
JP4644610B2 (ja) * | 2006-02-17 | 2011-03-02 | 京都市 | 等電点電気泳動装置 |
US20070209939A1 (en) * | 2006-03-10 | 2007-09-13 | Protein Forest, Inc. | Two-dimensional transfer device |
US8277761B2 (en) | 2006-08-03 | 2012-10-02 | Agilent Technologies, Inc. | Channelless fluidic sample transport medium |
EA201201363A1 (ru) * | 2006-11-21 | 2013-08-30 | Медимейт Холдинг Б.В. | Датчик ионов для текучей среды и способ его изготовления |
CN103499628A (zh) * | 2006-11-21 | 2014-01-08 | 麦迪美特控股有限公司 | 用于液体的离子传感器及其制造方法 |
EP2623975B1 (de) * | 2006-12-26 | 2016-02-03 | Sekisui Chemical Co., Ltd. | Verfahren zur Messung von stabilem Hämoglobin A1c und Glukose |
US20080272002A1 (en) * | 2007-05-03 | 2008-11-06 | Protein Forest, Inc. | System and Method for Proteomics |
GB2452239B (en) * | 2007-06-01 | 2012-08-29 | Kratos Analytical Ltd | Method and apparatus useful for imaging |
JP2009042004A (ja) * | 2007-08-07 | 2009-02-26 | Norio Okuyama | 電気泳動用支持体 |
KR20100053672A (ko) * | 2007-08-27 | 2010-05-20 | 테크니온 리서치 엔드 디벨로프먼트 화운데이션 엘티디. | 전기 분해에 의해 제어되는 ph 구배 및 등전위 포커싱에서의 그 사용 |
US20090110833A1 (en) * | 2007-10-31 | 2009-04-30 | Gala Industries, Inc. | Method for abrasion-resistant non-stick surface treatments for pelletization and drying process equipment components |
US9032441B2 (en) * | 2007-12-21 | 2015-05-12 | BrightTALK Limited | System and method for self management of a live web event |
WO2009102978A2 (en) * | 2008-02-14 | 2009-08-20 | University Of Notre Dame Du Lac | Ac field induced biomolecule crystallization and hydration cage disruption |
EP2146200A1 (de) * | 2008-07-16 | 2010-01-20 | Agilent Technologies, Inc. | Vorrichtung und Verfahren zur isoelektrischen Fokussierung |
WO2010023589A1 (en) * | 2008-08-28 | 2010-03-04 | Koninklijke Philips Electronics N.V. | Method for preparing a ph gradient in an isoelectric focusing biochip |
CN101556260B (zh) * | 2009-05-25 | 2012-01-11 | 北京理工大学 | 固定化pH梯度毛细管等电聚焦测定微生物等电点的方法 |
US9182411B2 (en) * | 2009-07-14 | 2015-11-10 | Colen Innovations, L.L.C. | Methods and apparatus for the detection and differentiation of non-sialated proteins from sialated proteins in a fluid sample |
CA2770518A1 (en) | 2009-08-18 | 2011-02-24 | Technion Research & Development Foundation Ltd. | Methods and devices of separating molecular analytes |
WO2011021196A2 (en) * | 2009-08-18 | 2011-02-24 | Technion Research & Development Foundation Ltd. | Proton concentration topographies, methods and devices for producing the same |
KR101431769B1 (ko) * | 2009-12-10 | 2014-08-20 | 삼성전자주식회사 | 당화 혈색소 측정용 원심력 기반의 미세유동 구조물, 당화 혈색소 측정용 원심력 기반 미세유동 장치 및 당화 혈색소의 측정방법 |
US20120190129A1 (en) * | 2011-01-20 | 2012-07-26 | Konica Minolta Holdings, Inc. | Test device, reaction apparatus and reactive test method |
US10023965B2 (en) | 2011-08-23 | 2018-07-17 | Board Of Regents, The University Of Texas System | Electrolytic buffer generator |
US8917096B2 (en) | 2012-11-15 | 2014-12-23 | International Business Machines Corporation | Determination of isoelectric points of biomolecules using capacitive sensors |
US9250206B2 (en) | 2013-04-04 | 2016-02-02 | International Business Machines Corporation | Controlled translocation of macromolecules employing a funnel nanopore structure and a gel |
CN103412029B (zh) * | 2013-06-26 | 2018-10-16 | 华东理工大学 | 基于芯片级别的平板电层析氨基酸分离装置及其使用方法 |
JP6791848B2 (ja) * | 2014-05-21 | 2020-11-25 | アンチェインド ラブス | 緩衝液の交換のためのシステム及び方法 |
EP3384274B1 (de) | 2015-11-30 | 2021-11-10 | Intabio, Inc. | Verfahren zur probencharakterisierung |
WO2019148198A1 (en) | 2018-01-29 | 2019-08-01 | Intabio, Inc. | Devices, methods and kits for sample characterization |
EP4439060A2 (de) | 2018-05-31 | 2024-10-02 | Intabio, Llc | Software für schnittstellenbildung zwischen mikrofluidischen systemen und massenspektrometrie |
CN112354571B (zh) * | 2019-07-11 | 2022-02-11 | 北京理工大学 | 一种多维微流控电泳芯片及检测装置,检测方法 |
US11285484B2 (en) | 2019-08-12 | 2022-03-29 | Intabio, Llc | Multichannel isoelectric focusing devices and high voltage power supplies |
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GB2036081B (en) | 1977-06-15 | 1982-08-25 | Nat Res Dev | Membrane electrophoresis |
US4473452A (en) | 1982-11-18 | 1984-09-25 | The Trustees Of Columbia University In The City Of New York | Electrophoresis using alternating transverse electric fields |
DE3876273T2 (de) | 1987-04-11 | 1993-05-27 | Ciba Geigy Ag | Isoelektrisches fokussierverfahren sowie einrichtung zur durchfuehrung dieses verfahrens. |
US5114555A (en) | 1988-01-05 | 1992-05-19 | Monsanto Company | Continuous isoelectric separation |
US4900414A (en) * | 1988-08-19 | 1990-02-13 | Drug Delivery Systems Inc. | Commercial separation system and method using electrokinetic techniques |
US5160594A (en) * | 1989-03-08 | 1992-11-03 | Board Of Regents Of The University Of Texas System | Apparatus and methods for isoelectric focusing of amphoteric substances incorporating ion selective membranes in electrode chambers |
GB9007922D0 (en) * | 1990-04-07 | 1990-06-06 | Oxford Virology Plc | A diagnostic test method |
US5336387A (en) | 1990-09-11 | 1994-08-09 | Bioseparations, Inc. | Electrical separator apparatus and method of counterflow gradient focusing |
US6017696A (en) | 1993-11-01 | 2000-01-25 | Nanogen, Inc. | Methods for electronic stringency control for molecular biological analysis and diagnostics |
JP2578285B2 (ja) * | 1992-02-28 | 1997-02-05 | 矢崎総業株式会社 | 防水コネクタ |
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US5571410A (en) | 1994-10-19 | 1996-11-05 | Hewlett Packard Company | Fully integrated miniaturized planar liquid sample handling and analysis device |
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GB9509410D0 (en) | 1995-05-10 | 1995-07-05 | Imperial College | Molecular imaging |
IT1282607B1 (it) | 1996-02-13 | 1998-03-31 | Pier Giorgio Righetti | Uso di gradienti multipli per l'analisi di mutazioni in dna genomico umano |
WO1998013689A1 (de) * | 1996-09-28 | 1998-04-02 | Fuhr Guenter | Verfahren und vorrichtung zur isoelektrischen teilchentrennung |
US5885430A (en) | 1996-10-04 | 1999-03-23 | Spectrumedix Corporation | Capillary tube holder for an electrophoretic apparatus |
US5773645A (en) | 1997-05-05 | 1998-06-30 | Bio-Rad Laboratories, Inc. | Two-dimensional electrophoresis device |
US5993627A (en) | 1997-06-24 | 1999-11-30 | Large Scale Biology Corporation | Automated system for two-dimensional electrophoresis |
US5968829A (en) * | 1997-09-05 | 1999-10-19 | Cytotherapeutics, Inc. | Human CNS neural stem cells |
AU9673198A (en) | 1997-10-02 | 1999-04-27 | Aclara Biosciences, Inc. | Capillary assays involving separation of free and bound species |
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US6576478B1 (en) | 1998-07-14 | 2003-06-10 | Zyomyx, Inc. | Microdevices for high-throughput screening of biomolecules |
US6406921B1 (en) | 1998-07-14 | 2002-06-18 | Zyomyx, Incorporated | Protein arrays for high-throughput screening |
DE69800630T2 (de) | 1998-07-29 | 2001-08-23 | Agilent Technologies, Inc. | Chip zur elektroforetischen Trennung von Molekülen und Verfahren zur Verwendung desselben |
SE9803224D0 (sv) | 1998-09-23 | 1998-09-23 | Amersham Pharm Biotech Ab | Method for separation of macromolecules |
US6240790B1 (en) | 1998-11-09 | 2001-06-05 | Agilent Technologies, Inc. | Device for high throughout sample processing, analysis and collection, and methods of use thereof |
US6156182A (en) | 1998-11-19 | 2000-12-05 | Bio-Rad Laboratories, Inc. | Encapsulated IPG Strips |
EP1044716A1 (de) * | 1999-03-13 | 2000-10-18 | Michael Dr. Cahill | Mikropräparative isoelektrischen Fokussierung |
US6638408B1 (en) * | 2000-04-03 | 2003-10-28 | The Wistar Institute | Method and device for separation of charged molecules by solution isoelectric focusing |
US6404905B1 (en) * | 2000-08-31 | 2002-06-11 | Large Scale Proteomics Corp. | Method and apparatus for impressing a master pattern to a gel image |
JP4108037B2 (ja) * | 2001-07-16 | 2008-06-25 | プロテイン, フォレスト, インコーポレイテッド | 生体分子の等電点によって生体分子を分析するためのバッファのアレイ |
-
2002
- 2002-07-16 JP JP2003514267A patent/JP4108037B2/ja not_active Expired - Fee Related
- 2002-07-16 US US10/198,071 patent/US7166202B2/en not_active Expired - Fee Related
- 2002-07-16 EP EP02756507A patent/EP1410029B1/de not_active Expired - Lifetime
- 2002-07-16 DE DE60222427T patent/DE60222427T2/de not_active Expired - Lifetime
- 2002-07-16 CN CNA028169719A patent/CN1549924A/zh active Pending
- 2002-07-16 AT AT02756507T patent/ATE373236T1/de not_active IP Right Cessation
- 2002-07-16 CA CA002454045A patent/CA2454045A1/en not_active Abandoned
- 2002-07-16 DK DK02756507T patent/DK1410029T3/da active
- 2002-07-16 IL IL15981002A patent/IL159810A0/xx unknown
- 2002-07-16 BR BRPI0211213-2A patent/BR0211213A/pt not_active IP Right Cessation
- 2002-07-16 AU AU2002322513A patent/AU2002322513B2/en not_active Ceased
- 2002-07-16 WO PCT/US2002/022714 patent/WO2003008977A2/en active IP Right Grant
-
2007
- 2007-01-04 US US11/619,796 patent/US7914656B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
DE60222427D1 (de) | 2007-10-25 |
US20070138015A1 (en) | 2007-06-21 |
WO2003008977A2 (en) | 2003-01-30 |
DE60222427T2 (de) | 2008-06-12 |
US7914656B2 (en) | 2011-03-29 |
JP2005526949A (ja) | 2005-09-08 |
AU2002322513B2 (en) | 2008-02-28 |
BR0211213A (pt) | 2006-05-23 |
US7166202B2 (en) | 2007-01-23 |
IL159810A0 (en) | 2004-06-20 |
US20030102215A1 (en) | 2003-06-05 |
JP4108037B2 (ja) | 2008-06-25 |
CN1549924A (zh) | 2004-11-24 |
CA2454045A1 (en) | 2003-01-30 |
DK1410029T3 (da) | 2008-01-07 |
WO2003008977A3 (en) | 2003-06-19 |
EP1410029B1 (de) | 2007-09-12 |
EP1410029A2 (de) | 2004-04-21 |
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Legal Events
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RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |