BR0211213A - matrizes, disposições ordenadas de elementos, sistemas e métodos para análise de biomoléculas - Google Patents
matrizes, disposições ordenadas de elementos, sistemas e métodos para análise de biomoléculasInfo
- Publication number
- BR0211213A BR0211213A BRPI0211213-2A BR0211213A BR0211213A BR 0211213 A BR0211213 A BR 0211213A BR 0211213 A BR0211213 A BR 0211213A BR 0211213 A BR0211213 A BR 0211213A
- Authority
- BR
- Brazil
- Prior art keywords
- arrays
- methods
- systems
- elements
- ordered arrangement
- Prior art date
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/416—Systems
- G01N27/447—Systems using electrophoresis
- G01N27/44756—Apparatus specially adapted therefor
- G01N27/44795—Isoelectric focusing
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
- G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
- G01N27/416—Systems
- G01N27/447—Systems using electrophoresis
- G01N27/44704—Details; Accessories
- G01N27/44747—Composition of gel or of carrier mixture
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Immunology (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Electrochemistry (AREA)
- Pathology (AREA)
- Dispersion Chemistry (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
"MATRIZES, DISPOSIçõES ORDENADAS DE ELEMENTOS, SISTEMAS E MéTODOS PARA ANáLISE DE BIOMOLéCULAS". A presente invenção se refere a matrizes, disposições ordenadas de elementos, sistemas e métodos para analisar biomoléculas por meio de seus pontos isoelétricos, opcionalmente, em combinação com uma análise em segunda dimensão. Os sortimentos de matrizes, disposições ordenadas de elementos, e sistemas aqui providos são úteis para induzir uma biomolécula sob influência de um campo elétrico a se acumular dentro de um tampão de IEF que compreende um valor de pH que é o mesmo como o do ponto isoelétrico da biomolécula. Os métodos são úteis, por exemplo, para os propósitos de pesquisa e diagnóstico.
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US30580201P | 2001-07-16 | 2001-07-16 | |
US31031601P | 2001-08-06 | 2001-08-06 | |
US34069801P | 2001-10-29 | 2001-10-29 | |
US37704402P | 2002-04-30 | 2002-04-30 | |
PCT/US2002/022714 WO2003008977A2 (en) | 2001-07-16 | 2002-07-16 | Arrays of buffers for analysing biomolecules by their isoelectric point |
Publications (1)
Publication Number | Publication Date |
---|---|
BR0211213A true BR0211213A (pt) | 2006-05-23 |
Family
ID=27501888
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BRPI0211213-2A BR0211213A (pt) | 2001-07-16 | 2002-07-16 | matrizes, disposições ordenadas de elementos, sistemas e métodos para análise de biomoléculas |
Country Status (12)
Country | Link |
---|---|
US (2) | US7166202B2 (pt) |
EP (1) | EP1410029B1 (pt) |
JP (1) | JP4108037B2 (pt) |
CN (1) | CN1549924A (pt) |
AT (1) | ATE373236T1 (pt) |
AU (1) | AU2002322513B2 (pt) |
BR (1) | BR0211213A (pt) |
CA (1) | CA2454045A1 (pt) |
DE (1) | DE60222427T2 (pt) |
DK (1) | DK1410029T3 (pt) |
IL (1) | IL159810A0 (pt) |
WO (1) | WO2003008977A2 (pt) |
Families Citing this family (38)
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EP1410029B1 (en) * | 2001-07-16 | 2007-09-12 | Protein Forest, Inc. | Arrays of buffers for analysing biomolecules by their isoelectric point |
WO2004104548A2 (en) | 2003-05-09 | 2004-12-02 | Invitrogen Corporation | Solution phase electrophoresis device, components, and methods |
US7622028B2 (en) | 2003-05-09 | 2009-11-24 | Life Technologies Corporation | Solution phase electrophoresis device, components, and methods |
JP2007504215A (ja) * | 2003-09-03 | 2007-03-01 | バイオフォームズ | 生体分子を急速に結晶化するための方法及び装置 |
EP1668350B1 (en) * | 2003-09-24 | 2012-06-13 | Agilent Technologies, Inc. | Electrophoretic separation of amphoteric molecules |
EP1685395A2 (en) * | 2003-11-05 | 2006-08-02 | EXACT Sciences Corporation | Repetitive reversed-field affinity electrophoresis and uses therefor |
US7815783B2 (en) * | 2004-03-17 | 2010-10-19 | Bio-Rad Laboratories, Inc. | Multi-compartment filter and method of filtering using same |
JP4644610B2 (ja) * | 2006-02-17 | 2011-03-02 | 京都市 | 等電点電気泳動装置 |
US20070209939A1 (en) * | 2006-03-10 | 2007-09-13 | Protein Forest, Inc. | Two-dimensional transfer device |
WO2008014825A1 (en) | 2006-08-03 | 2008-02-07 | Agilent Technologies, Inc. | Channelless fluidic sample transport medium |
WO2008061542A1 (en) * | 2006-11-21 | 2008-05-29 | Medimate Holding B.V. | Ion sensor for fluid and method for its manufacture |
CN103499628A (zh) * | 2006-11-21 | 2014-01-08 | 麦迪美特控股有限公司 | 用于液体的离子传感器及其制造方法 |
EP2105735B1 (en) * | 2006-12-26 | 2014-11-26 | Sekisui Chemical Co., Ltd. | STABLE HEMOGLOBIN A1c MEASUREMENT METHOD AND ELECTROPHORESIS APPARATUS |
US20080272002A1 (en) * | 2007-05-03 | 2008-11-06 | Protein Forest, Inc. | System and Method for Proteomics |
GB2452239B (en) * | 2007-06-01 | 2012-08-29 | Kratos Analytical Ltd | Method and apparatus useful for imaging |
JP2009042004A (ja) * | 2007-08-07 | 2009-02-26 | Norio Okuyama | 電気泳動用支持体 |
AU2008293381B2 (en) | 2007-08-27 | 2012-07-19 | Technion Research & Development Foundation Ltd. | pH gradients controlled by electrolysis, and their use in isoelectric focusing |
US20090110833A1 (en) * | 2007-10-31 | 2009-04-30 | Gala Industries, Inc. | Method for abrasion-resistant non-stick surface treatments for pelletization and drying process equipment components |
US9032441B2 (en) * | 2007-12-21 | 2015-05-12 | BrightTALK Limited | System and method for self management of a live web event |
US20110042215A1 (en) * | 2008-02-14 | 2011-02-24 | Diana Hou | Ac field induced biomolecule cyrstallization and hydration cage disruption |
EP2146200A1 (en) * | 2008-07-16 | 2010-01-20 | Agilent Technologies, Inc. | Device and method for isoelectric focusing |
WO2010023589A1 (en) * | 2008-08-28 | 2010-03-04 | Koninklijke Philips Electronics N.V. | Method for preparing a ph gradient in an isoelectric focusing biochip |
CN101556260B (zh) * | 2009-05-25 | 2012-01-11 | 北京理工大学 | 固定化pH梯度毛细管等电聚焦测定微生物等电点的方法 |
US9182411B2 (en) * | 2009-07-14 | 2015-11-10 | Colen Innovations, L.L.C. | Methods and apparatus for the detection and differentiation of non-sialated proteins from sialated proteins in a fluid sample |
JP5635609B2 (ja) | 2009-08-18 | 2014-12-03 | テクニオン リサーチ アンド ディベロップメント ファウンデーションリミテッド | 分子状分析物を分離する方法およびデバイス |
AU2010286047B2 (en) * | 2009-08-18 | 2014-09-25 | Technion Research & Development Foundation Ltd. | Proton concentration topographies, methods and devices for producing the same |
KR101431769B1 (ko) * | 2009-12-10 | 2014-08-20 | 삼성전자주식회사 | 당화 혈색소 측정용 원심력 기반의 미세유동 구조물, 당화 혈색소 측정용 원심력 기반 미세유동 장치 및 당화 혈색소의 측정방법 |
US20120190129A1 (en) * | 2011-01-20 | 2012-07-26 | Konica Minolta Holdings, Inc. | Test device, reaction apparatus and reactive test method |
WO2013028924A1 (en) * | 2011-08-23 | 2013-02-28 | Board Of Regents, The University Of Texas System | Electrolytic buffer generator |
US8917096B2 (en) | 2012-11-15 | 2014-12-23 | International Business Machines Corporation | Determination of isoelectric points of biomolecules using capacitive sensors |
US9250206B2 (en) | 2013-04-04 | 2016-02-02 | International Business Machines Corporation | Controlled translocation of macromolecules employing a funnel nanopore structure and a gel |
CN103412029B (zh) * | 2013-06-26 | 2018-10-16 | 华东理工大学 | 基于芯片级别的平板电层析氨基酸分离装置及其使用方法 |
CA3159833A1 (en) * | 2014-05-21 | 2015-11-26 | Unchained Labs | Systems and methods for exchange of buffer solutions |
EP3957986B1 (en) | 2015-11-30 | 2024-09-18 | Intabio, Llc | Methods for sample characterization |
KR102691269B1 (ko) | 2018-01-29 | 2024-08-05 | 인타바이오 엘엘씨 | 샘플 특성화를 위한 장치, 방법 및 키트 |
WO2019232397A1 (en) | 2018-05-31 | 2019-12-05 | Intabio, Inc. | Software for microfluidic systems interfacing with mass spectrometry |
CN110327994B (zh) * | 2019-07-11 | 2020-12-08 | 北京理工大学 | 一种多维微流控电泳芯片及检测装置,检测方法 |
US11285484B2 (en) | 2019-08-12 | 2022-03-29 | Intabio, Llc | Multichannel isoelectric focusing devices and high voltage power supplies |
Family Cites Families (33)
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DE2861803D1 (en) | 1977-06-15 | 1982-07-01 | Nat Res Dev | Electrophoresis membranes, their use in a separation method and separation apparatus |
US4473452A (en) | 1982-11-18 | 1984-09-25 | The Trustees Of Columbia University In The City Of New York | Electrophoresis using alternating transverse electric fields |
ES2037273T3 (es) | 1987-04-11 | 1993-06-16 | Ciba-Geigy Ag | Proceso de focalizacion isoelectrica y medios para llevar a cabo dicho proceso. |
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US4900414A (en) * | 1988-08-19 | 1990-02-13 | Drug Delivery Systems Inc. | Commercial separation system and method using electrokinetic techniques |
US5160594A (en) * | 1989-03-08 | 1992-11-03 | Board Of Regents Of The University Of Texas System | Apparatus and methods for isoelectric focusing of amphoteric substances incorporating ion selective membranes in electrode chambers |
GB9007922D0 (en) * | 1990-04-07 | 1990-06-06 | Oxford Virology Plc | A diagnostic test method |
US5336387A (en) | 1990-09-11 | 1994-08-09 | Bioseparations, Inc. | Electrical separator apparatus and method of counterflow gradient focusing |
US6017696A (en) | 1993-11-01 | 2000-01-25 | Nanogen, Inc. | Methods for electronic stringency control for molecular biological analysis and diagnostics |
JP2578285B2 (ja) * | 1992-02-28 | 1997-02-05 | 矢崎総業株式会社 | 防水コネクタ |
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US5630924A (en) | 1995-04-20 | 1997-05-20 | Perseptive Biosystems, Inc. | Compositions, methods and apparatus for ultrafast electroseparation analysis |
GB9509410D0 (en) | 1995-05-10 | 1995-07-05 | Imperial College | Molecular imaging |
IT1282607B1 (it) | 1996-02-13 | 1998-03-31 | Pier Giorgio Righetti | Uso di gradienti multipli per l'analisi di mutazioni in dna genomico umano |
EP0928418B1 (de) * | 1996-09-28 | 2003-12-17 | Fuhr, Günter | Verfahren und vorrichtung zur isoelektrischen teilchentrennung |
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US5968829A (en) * | 1997-09-05 | 1999-10-19 | Cytotherapeutics, Inc. | Human CNS neural stem cells |
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-
2002
- 2002-07-16 EP EP02756507A patent/EP1410029B1/en not_active Expired - Lifetime
- 2002-07-16 CN CNA028169719A patent/CN1549924A/zh active Pending
- 2002-07-16 AT AT02756507T patent/ATE373236T1/de not_active IP Right Cessation
- 2002-07-16 US US10/198,071 patent/US7166202B2/en not_active Expired - Fee Related
- 2002-07-16 CA CA002454045A patent/CA2454045A1/en not_active Abandoned
- 2002-07-16 BR BRPI0211213-2A patent/BR0211213A/pt not_active IP Right Cessation
- 2002-07-16 WO PCT/US2002/022714 patent/WO2003008977A2/en active IP Right Grant
- 2002-07-16 DK DK02756507T patent/DK1410029T3/da active
- 2002-07-16 AU AU2002322513A patent/AU2002322513B2/en not_active Ceased
- 2002-07-16 DE DE60222427T patent/DE60222427T2/de not_active Expired - Lifetime
- 2002-07-16 IL IL15981002A patent/IL159810A0/xx unknown
- 2002-07-16 JP JP2003514267A patent/JP4108037B2/ja not_active Expired - Fee Related
-
2007
- 2007-01-04 US US11/619,796 patent/US7914656B2/en active Active
Also Published As
Publication number | Publication date |
---|---|
DE60222427D1 (de) | 2007-10-25 |
CN1549924A (zh) | 2004-11-24 |
US20070138015A1 (en) | 2007-06-21 |
AU2002322513B2 (en) | 2008-02-28 |
WO2003008977A3 (en) | 2003-06-19 |
US7914656B2 (en) | 2011-03-29 |
DK1410029T3 (da) | 2008-01-07 |
JP2005526949A (ja) | 2005-09-08 |
EP1410029A2 (en) | 2004-04-21 |
JP4108037B2 (ja) | 2008-06-25 |
DE60222427T2 (de) | 2008-06-12 |
IL159810A0 (en) | 2004-06-20 |
US20030102215A1 (en) | 2003-06-05 |
CA2454045A1 (en) | 2003-01-30 |
EP1410029B1 (en) | 2007-09-12 |
US7166202B2 (en) | 2007-01-23 |
WO2003008977A2 (en) | 2003-01-30 |
ATE373236T1 (de) | 2007-09-15 |
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Legal Events
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B08F | Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette] |
Free format text: REFERENTE A 7A E 8A ANUIDADES. |
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B08K | Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette] |
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