DE3721430A1 - Verfahren zur herstellung von 1-(3'-(mercapto)-(2's)-(methyl)-propionyl)-pyrrolidin-(2s)-carbonsaeure oder ihren salzen - Google Patents

Verfahren zur herstellung von 1-(3'-(mercapto)-(2's)-(methyl)-propionyl)-pyrrolidin-(2s)-carbonsaeure oder ihren salzen

Info

Publication number
DE3721430A1
DE3721430A1 DE19873721430 DE3721430A DE3721430A1 DE 3721430 A1 DE3721430 A1 DE 3721430A1 DE 19873721430 DE19873721430 DE 19873721430 DE 3721430 A DE3721430 A DE 3721430A DE 3721430 A1 DE3721430 A1 DE 3721430A1
Authority
DE
Germany
Prior art keywords
methyl
propionyl
pyrrolidine
carboxylic acid
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
DE19873721430
Other languages
German (de)
English (en)
Inventor
Janos Dr Fischer
Tamas Dr Fodor
Laszlo Dobay
Bela Dr Stefko
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Egyt Gyogyszervegyeszeti Gyar
Egis Pharmaceuticals PLC
Original Assignee
Egyt Gyogyszervegyeszeti Gyar
Egis Pharmaceuticals PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Egyt Gyogyszervegyeszeti Gyar, Egis Pharmaceuticals PLC filed Critical Egyt Gyogyszervegyeszeti Gyar
Publication of DE3721430A1 publication Critical patent/DE3721430A1/de
Withdrawn legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/08Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon radicals, substituted by hetero atoms, attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/04Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D207/10Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/16Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
DE19873721430 1986-06-27 1987-06-29 Verfahren zur herstellung von 1-(3'-(mercapto)-(2's)-(methyl)-propionyl)-pyrrolidin-(2s)-carbonsaeure oder ihren salzen Withdrawn DE3721430A1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU862689A HU196959B (en) 1986-06-27 1986-06-27 Process for producing merkapto-acyl-proline derivatives

Publications (1)

Publication Number Publication Date
DE3721430A1 true DE3721430A1 (de) 1988-01-28

Family

ID=10960651

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19873721430 Withdrawn DE3721430A1 (de) 1986-06-27 1987-06-29 Verfahren zur herstellung von 1-(3'-(mercapto)-(2's)-(methyl)-propionyl)-pyrrolidin-(2s)-carbonsaeure oder ihren salzen

Country Status (21)

Country Link
JP (1) JPS6327475A (es)
KR (1) KR900007217B1 (es)
CN (1) CN87104388A (es)
AR (1) AR243159A1 (es)
AT (2) AT395012B (es)
CH (1) CH673279A5 (es)
CS (1) CS276394B6 (es)
DD (1) DD263757A5 (es)
DE (1) DE3721430A1 (es)
DK (1) DK329787A (es)
ES (1) ES2004451A6 (es)
FI (1) FI87770C (es)
GR (1) GR871012B (es)
HU (1) HU196959B (es)
IT (1) IT1206792B (es)
NO (1) NO168941C (es)
PL (1) PL153449B1 (es)
PT (1) PT85190B (es)
SE (1) SE462751B (es)
SU (1) SU1650007A3 (es)
YU (1) YU46319B (es)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2667065A1 (fr) * 1990-09-21 1992-03-27 Egyt Gyogyszervegyeszeti Gyar Procede pour preparer la 1-[(2s)-3-mercapto-2-methyl-1-oxopropyl]-l-proline.

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE421551B (sv) * 1980-03-26 1982-01-04 Sandvik Ab Borrverktyg for rotations- och/eller slagborrning
JPS62125081A (ja) * 1985-11-21 1987-06-06 キングプリンテイング株式会社 捺染方法
PT928191E (pt) * 1996-09-26 2003-01-31 Meditor Pharmaceuticals Ltd Formulacoes farmaceuticas compreendendo derivados de s-alquilisotiouronio
CN103086939A (zh) * 2011-10-28 2013-05-08 华中药业股份有限公司 1-(3-溴-2-d-甲基丙酰基)吡咯烷-2-羧酸的重结晶方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU509899B2 (en) * 1976-02-13 1980-05-29 E.R. Squibb & Sons, Inc. Proline derivatives and related compounds
IL58849A (en) * 1978-12-11 1983-03-31 Merck & Co Inc Carboxyalkyl dipeptides and derivatives thereof,their preparation and pharmaceutical compositions containing them
GB2065643B (en) * 1979-12-13 1983-08-24 Kanegafuchi Chemical Ind Optically active n-mercaptoalkanoylamino acids
IE54551B1 (en) * 1982-01-22 1989-11-22 Ici Plc Amide derivatives
KR860001391B1 (ko) * 1984-07-23 1986-09-22 보령제약 주식회사 피롤리딘 유도체의 제조방법

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
US-Z: Chemical Abstracts, Bd. 105, 1986, 78824c *
US-Z: Chemical Abstracts, Bd. 96, 1982, 20459s *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2667065A1 (fr) * 1990-09-21 1992-03-27 Egyt Gyogyszervegyeszeti Gyar Procede pour preparer la 1-[(2s)-3-mercapto-2-methyl-1-oxopropyl]-l-proline.
GR910100391A (el) * 1990-09-21 1992-09-11 Egyt Gyogyszervegyeszeti Gyar Μέ?οδος για την παρασκευή 1-[(2S)-3-μερκαπτο-με?υλ-L-οξοπροπυλ] 1-προλίνης.

Also Published As

Publication number Publication date
SE8702654D0 (sv) 1987-06-26
HU196959B (en) 1989-02-28
YU118187A (en) 1988-04-30
AT395012B (de) 1992-08-25
NO872690D0 (no) 1987-06-26
SE462751B (sv) 1990-08-27
ATA91186A (de) 1992-01-15
NO872690L (no) 1987-12-28
IT8721085A0 (it) 1987-06-26
DK329787A (da) 1987-12-28
KR880000392A (ko) 1988-03-25
DD263757A5 (de) 1989-01-11
FI87770B (fi) 1992-11-13
DK329787D0 (da) 1987-06-26
YU46319B (sh) 1993-05-28
JPS6327475A (ja) 1988-02-05
NO168941B (no) 1992-01-13
ATA162087A (de) 1988-06-15
GR871012B (en) 1987-11-02
PT85190B (pt) 1990-03-30
PT85190A (en) 1987-07-01
SE8702654L (sv) 1987-12-28
AT387381B (de) 1989-01-10
KR900007217B1 (ko) 1990-10-05
SU1650007A3 (ru) 1991-05-15
PL266478A1 (en) 1988-06-09
CN87104388A (zh) 1988-03-02
AR243159A1 (es) 1993-07-30
ES2004451A6 (es) 1989-01-01
CS479487A3 (en) 1992-01-15
PL153449B1 (en) 1991-04-30
IT1206792B (it) 1989-05-03
NO168941C (no) 1992-04-29
FI872859A (fi) 1987-12-28
CH673279A5 (es) 1990-02-28
FI87770C (fi) 1993-02-25
FI872859A0 (fi) 1987-06-26
HUT44490A (en) 1988-03-28
CS276394B6 (en) 1992-05-13

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Legal Events

Date Code Title Description
OM8 Search report available as to paragraph 43 lit. 1 sentence 1 patent law
8141 Disposal/no request for examination