DE3618724C2 - N-[3-(Nitro)-chinol-4-yl]-carboxamidinamide, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel - Google Patents

N-[3-(Nitro)-chinol-4-yl]-carboxamidinamide, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel

Info

Publication number
DE3618724C2
DE3618724C2 DE3618724A DE3618724A DE3618724C2 DE 3618724 C2 DE3618724 C2 DE 3618724C2 DE 3618724 A DE3618724 A DE 3618724A DE 3618724 A DE3618724 A DE 3618724A DE 3618724 C2 DE3618724 C2 DE 3618724C2
Authority
DE
Germany
Prior art keywords
nitro
general formula
quinol
radical
carboxamidinamides
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE3618724A
Other languages
German (de)
English (en)
Other versions
DE3618724A1 (de
Inventor
Geb Poldermann Berenyi
Laszlo Dr Varga
Laszlo Dipl Chem Dr Pallos
Lujza Dr Petocz
Laszlo Ladanyi
Peter Dipl Chem Dr Tompe
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Egyt Gyogyszervegyeszeti Gyar
Egis Gyógyszergyár Zrt
Original Assignee
Egyt Gyogyszervegyeszeti Gyar
Egis Gyógyszergyár Zrt
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Egyt Gyogyszervegyeszeti Gyar, Egis Gyógyszergyár Zrt filed Critical Egyt Gyogyszervegyeszeti Gyar
Publication of DE3618724A1 publication Critical patent/DE3618724A1/de
Application granted granted Critical
Publication of DE3618724C2 publication Critical patent/DE3618724C2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38—Nitrogen atoms
    • C07D215/42—Nitrogen atoms attached in position 4
    • C07D215/46—Nitrogen atoms attached in position 4 with hydrocarbon radicals, substituted by nitrogen atoms, attached to said nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Quinoline Compounds (AREA)
DE3618724A 1985-06-04 1986-06-04 N-[3-(Nitro)-chinol-4-yl]-carboxamidinamide, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel Expired - Fee Related DE3618724C2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU852193A HU195487B (en) 1985-06-04 1985-06-04 Process for producing quinoline derivatives

Publications (2)

Publication Number Publication Date
DE3618724A1 DE3618724A1 (de) 1987-01-08
DE3618724C2 true DE3618724C2 (de) 1994-06-16

Family

ID=10958222

Family Applications (1)

Application Number Title Priority Date Filing Date
DE3618724A Expired - Fee Related DE3618724C2 (de) 1985-06-04 1986-06-04 N-[3-(Nitro)-chinol-4-yl]-carboxamidinamide, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel

Country Status (28)

Country Link
US (1) US4652562A (enExample)
JP (1) JPS6248668A (enExample)
KR (1) KR930006775B1 (enExample)
CN (1) CN1012957B (enExample)
AT (1) AT392469B (enExample)
AU (1) AU588883B2 (enExample)
BE (1) BE904864A (enExample)
CA (1) CA1266650A (enExample)
CH (1) CH668069A5 (enExample)
CS (1) CS257793B2 (enExample)
DD (1) DD247448A5 (enExample)
DE (1) DE3618724C2 (enExample)
DK (1) DK162841C (enExample)
ES (1) ES8707231A1 (enExample)
FI (1) FI82451C (enExample)
FR (1) FR2582835B1 (enExample)
GB (1) GB2176185B (enExample)
GR (1) GR861452B (enExample)
HU (1) HU195487B (enExample)
IL (1) IL79024A0 (enExample)
IT (1) IT1204377B (enExample)
NL (1) NL8601434A (enExample)
NO (1) NO165635C (enExample)
PH (1) PH24135A (enExample)
PL (1) PL146498B1 (enExample)
PT (1) PT82712B (enExample)
SE (1) SE466308B (enExample)
SU (1) SU1398773A3 (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6331286B1 (en) 1998-12-21 2001-12-18 Photogen, Inc. Methods for high energy phototherapeutics
US8974363B2 (en) * 1997-12-11 2015-03-10 Provectus Pharmatech, Inc. Topical medicaments and methods for photodynamic treatment of disease
US20090117199A1 (en) * 1998-08-06 2009-05-07 Scott Timothy C Method of treatment of cancer
US8557298B2 (en) * 1998-08-06 2013-10-15 Provectus Pharmatech, Inc. Medicaments for chemotherapeutic treatment of disease
US8470296B2 (en) * 1998-12-21 2013-06-25 Provectus Pharmatech, Inc. Intracorporeal medicaments for high energy phototherapeutic treatment of disease
US20020001567A1 (en) * 1998-12-21 2002-01-03 Photogen, Inc. Intracorporeal medicaments for high energy phototherapeutic treatment of disease
US7384623B1 (en) 1998-12-21 2008-06-10 Provectus Pharmatech, Inc. High energy phototherapeutic agents
EP1719770A3 (en) * 2000-09-21 2008-03-05 Smithkline Beecham Plc Quinoline derivatives as antibacterials

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU165520B (enExample) * 1972-05-05 1974-09-28
IE47458B1 (en) * 1977-11-07 1984-03-21 Leo Pharm Prod Ltd Quinolylguanidine derivatives

Also Published As

Publication number Publication date
DK162841C (da) 1992-05-04
AT392469B (de) 1991-04-10
BE904864A (fr) 1986-12-03
FI82451C (fi) 1991-03-11
ES8707231A1 (es) 1987-07-16
NL8601434A (nl) 1987-01-02
FI862381A7 (fi) 1986-12-05
SE466308B (sv) 1992-01-27
SU1398773A3 (ru) 1988-05-23
PL146498B1 (en) 1989-02-28
DK162841B (da) 1991-12-16
IT1204377B (it) 1989-03-01
GB8613530D0 (en) 1986-07-09
DK262186D0 (da) 1986-06-04
SE8602524L (sv) 1986-12-05
GR861452B (en) 1986-10-03
FI82451B (fi) 1990-11-30
PT82712B (pt) 1988-04-21
HUT41008A (en) 1987-03-30
NO862230L (no) 1986-12-05
ES555708A0 (es) 1987-07-16
SE8602524D0 (sv) 1986-06-04
AU5834486A (en) 1986-12-11
ATA149286A (de) 1990-09-15
US4652562A (en) 1987-03-24
DK262186A (da) 1986-12-05
CA1266650A (en) 1990-03-13
NO862230D0 (no) 1986-06-04
HU195487B (en) 1988-05-30
CN1012957B (zh) 1991-06-26
DE3618724A1 (de) 1987-01-08
JPH0515705B2 (enExample) 1993-03-02
JPS6248668A (ja) 1987-03-03
PT82712A (en) 1986-07-01
CS257793B2 (en) 1988-06-15
KR930006775B1 (ko) 1993-07-23
NO165635C (no) 1991-03-13
AU588883B2 (en) 1989-09-28
FR2582835A1 (fr) 1986-12-05
IT8620667A0 (it) 1986-06-04
FI862381A0 (fi) 1986-06-04
KR870000324A (ko) 1987-02-17
DD247448A5 (de) 1987-07-08
GB2176185A (en) 1986-12-17
NO165635B (no) 1990-12-03
CN86103688A (zh) 1987-02-11
CH668069A5 (de) 1988-11-30
IL79024A0 (en) 1986-09-30
GB2176185B (en) 1988-09-28
PH24135A (en) 1990-03-05
FR2582835B1 (fr) 1989-01-06

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Legal Events

Date Code Title Description
8110 Request for examination paragraph 44
D2 Grant after examination
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee