ES8707231A1 - Procedimiento para preparar nuevos derivados de la quinoleina y sus sales complementarias acidas - Google Patents
Procedimiento para preparar nuevos derivados de la quinoleina y sus sales complementarias acidasInfo
- Publication number
- ES8707231A1 ES8707231A1 ES555708A ES555708A ES8707231A1 ES 8707231 A1 ES8707231 A1 ES 8707231A1 ES 555708 A ES555708 A ES 555708A ES 555708 A ES555708 A ES 555708A ES 8707231 A1 ES8707231 A1 ES 8707231A1
- Authority
- ES
- Spain
- Prior art keywords
- lower alkyl
- stands
- general formula
- image
- quinoline derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/38—Nitrogen atoms
- C07D215/42—Nitrogen atoms attached in position 4
- C07D215/46—Nitrogen atoms attached in position 4 with hydrocarbon radicals, substituted by nitrogen atoms, attached to said nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Quinoline Compounds (AREA)
Abstract
PROCEDIMIENTO PARA LA OBTENCION DE DERIVADOS DE QUINOLEINA, DE FORMULA (I) Y DE SUS SALES COMPLEMENTARIAS ACIDAS. COMPRENDE LA REACCION DE UNA QUINOLINA DE FORMULA (II), O UNA DE SUS SALES COMPLEMENTARIAS ACIDAS, CON UN DERIVADO DE LA GUANIDINA DE FORMULA (III) O UNA DE SUS SALES COMPLEMENTARIAS ACIDAS, EN UN DISOLVENTE ORGANICO INERTE, EN PRESENCIA DE UNA BASE, A UNA TEMPERATURA COMPRENDIDA ENTRE 0JC Y 15JC, PARA FORMAR EL COMPUESTO DE FORMULA (I), EN LAS QUE X, R1 Y R2 PUEDEN SER VARIOS RADICALES, Y ES UN GRUPO RESIDUAL Y N VALE 1-3. ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS, COMO RADIOSENSIBILIZADORES, PARA EL TRATAMIENTO DEL CANCER.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| HU852193A HU195487B (en) | 1985-06-04 | 1985-06-04 | Process for producing quinoline derivatives |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES555708A0 ES555708A0 (es) | 1987-07-16 |
| ES8707231A1 true ES8707231A1 (es) | 1987-07-16 |
Family
ID=10958222
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES555708A Expired ES8707231A1 (es) | 1985-06-04 | 1986-06-04 | Procedimiento para preparar nuevos derivados de la quinoleina y sus sales complementarias acidas |
Country Status (28)
| Country | Link |
|---|---|
| US (1) | US4652562A (es) |
| JP (1) | JPS6248668A (es) |
| KR (1) | KR930006775B1 (es) |
| CN (1) | CN1012957B (es) |
| AT (1) | AT392469B (es) |
| AU (1) | AU588883B2 (es) |
| BE (1) | BE904864A (es) |
| CA (1) | CA1266650A (es) |
| CH (1) | CH668069A5 (es) |
| CS (1) | CS257793B2 (es) |
| DD (1) | DD247448A5 (es) |
| DE (1) | DE3618724C2 (es) |
| DK (1) | DK162841C (es) |
| ES (1) | ES8707231A1 (es) |
| FI (1) | FI82451C (es) |
| FR (1) | FR2582835B1 (es) |
| GB (1) | GB2176185B (es) |
| GR (1) | GR861452B (es) |
| HU (1) | HU195487B (es) |
| IL (1) | IL79024A0 (es) |
| IT (1) | IT1204377B (es) |
| NL (1) | NL8601434A (es) |
| NO (1) | NO165635C (es) |
| PH (1) | PH24135A (es) |
| PL (1) | PL146498B1 (es) |
| PT (1) | PT82712B (es) |
| SE (1) | SE466308B (es) |
| SU (1) | SU1398773A3 (es) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6331286B1 (en) | 1998-12-21 | 2001-12-18 | Photogen, Inc. | Methods for high energy phototherapeutics |
| US8974363B2 (en) * | 1997-12-11 | 2015-03-10 | Provectus Pharmatech, Inc. | Topical medicaments and methods for photodynamic treatment of disease |
| US8557298B2 (en) * | 1998-08-06 | 2013-10-15 | Provectus Pharmatech, Inc. | Medicaments for chemotherapeutic treatment of disease |
| US20090117199A1 (en) * | 1998-08-06 | 2009-05-07 | Scott Timothy C | Method of treatment of cancer |
| US7384623B1 (en) | 1998-12-21 | 2008-06-10 | Provectus Pharmatech, Inc. | High energy phototherapeutic agents |
| US20020001567A1 (en) * | 1998-12-21 | 2002-01-03 | Photogen, Inc. | Intracorporeal medicaments for high energy phototherapeutic treatment of disease |
| US8470296B2 (en) * | 1998-12-21 | 2013-06-25 | Provectus Pharmatech, Inc. | Intracorporeal medicaments for high energy phototherapeutic treatment of disease |
| DE60119939T2 (de) * | 2000-09-21 | 2006-11-30 | Smithkline Beecham P.L.C., Brentford | Chinolinderivate als antibakterielle mittel |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HU165520B (es) * | 1972-05-05 | 1974-09-28 | ||
| IE47458B1 (en) * | 1977-11-07 | 1984-03-21 | Leo Pharm Prod Ltd | Quinolylguanidine derivatives |
-
1985
- 1985-06-04 HU HU852193A patent/HU195487B/hu not_active IP Right Cessation
-
1986
- 1986-05-28 CH CH2153/86A patent/CH668069A5/de not_active IP Right Cessation
- 1986-05-30 DD DD86290766A patent/DD247448A5/de not_active IP Right Cessation
- 1986-06-03 BE BE0/216734A patent/BE904864A/fr not_active IP Right Cessation
- 1986-06-03 PH PH33848A patent/PH24135A/en unknown
- 1986-06-03 CN CN86103688A patent/CN1012957B/zh not_active Expired
- 1986-06-03 AT AT1492/86A patent/AT392469B/de not_active IP Right Cessation
- 1986-06-03 KR KR1019860004409A patent/KR930006775B1/ko not_active IP Right Cessation
- 1986-06-04 IT IT20667/86A patent/IT1204377B/it active
- 1986-06-04 PL PL1986259871A patent/PL146498B1/pl unknown
- 1986-06-04 SE SE8602524A patent/SE466308B/sv not_active IP Right Cessation
- 1986-06-04 FI FI862381A patent/FI82451C/fi not_active IP Right Cessation
- 1986-06-04 AU AU58344/86A patent/AU588883B2/en not_active Ceased
- 1986-06-04 JP JP61130006A patent/JPS6248668A/ja active Granted
- 1986-06-04 GB GB08613530A patent/GB2176185B/en not_active Expired
- 1986-06-04 NO NO862230A patent/NO165635C/no unknown
- 1986-06-04 GR GR861452A patent/GR861452B/el unknown
- 1986-06-04 SU SU864027590A patent/SU1398773A3/ru active
- 1986-06-04 DK DK262186A patent/DK162841C/da not_active IP Right Cessation
- 1986-06-04 PT PT82712A patent/PT82712B/pt unknown
- 1986-06-04 NL NL8601434A patent/NL8601434A/nl not_active Application Discontinuation
- 1986-06-04 CA CA000510779A patent/CA1266650A/en not_active Expired - Lifetime
- 1986-06-04 US US06/870,396 patent/US4652562A/en not_active Expired - Fee Related
- 1986-06-04 DE DE3618724A patent/DE3618724C2/de not_active Expired - Fee Related
- 1986-06-04 CS CS864112A patent/CS257793B2/cs unknown
- 1986-06-04 FR FR8608039A patent/FR2582835B1/fr not_active Expired
- 1986-06-04 ES ES555708A patent/ES8707231A1/es not_active Expired
- 1986-06-04 IL IL79024A patent/IL79024A0/xx not_active IP Right Cessation
Also Published As
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD1A | Patent lapsed |
Effective date: 19990405 |