ES8200669A1 - Un procedimiento para la preparacion de nuevos compuestos iminicos heterociclicos - Google Patents
Un procedimiento para la preparacion de nuevos compuestos iminicos heterociclicosInfo
- Publication number
- ES8200669A1 ES8200669A1 ES493859A ES493859A ES8200669A1 ES 8200669 A1 ES8200669 A1 ES 8200669A1 ES 493859 A ES493859 A ES 493859A ES 493859 A ES493859 A ES 493859A ES 8200669 A1 ES8200669 A1 ES 8200669A1
- Authority
- ES
- Spain
- Prior art keywords
- alkyl
- phenyl
- optionally substituted
- alkoxy
- halogen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D265/04—1,3-Oxazines; Hydrogenated 1,3-oxazines
- C07D265/06—1,3-Oxazines; Hydrogenated 1,3-oxazines not condensed with other rings
- C07D265/08—1,3-Oxazines; Hydrogenated 1,3-oxazines not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D263/28—Nitrogen atoms not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/08—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D277/12—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/18—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D279/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms
- C07D279/04—1,3-Thiazines; Hydrogenated 1,3-thiazines
- C07D279/06—1,3-Thiazines; Hydrogenated 1,3-thiazines not condensed with other rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
PROCEDIMIENTO DE OBTENCION DE COMPUESTOS IMINICOS HETEROCICLICOS. CONSISTE EN HACER REACCIONAR UN COMPUESTO DE FORMULA GENERAL (I) CON UN COMPUESTO IMINICO (II). SI SE DESEA LA BASE LIBRE (III) OBTENIDA SE TRANSFORMA EN LA SAL FARMACEUTICAMENTE ACEPTABLE. X REPRESENTA OXIGENO O AZUFRE; N ES 0 O 1, R7 E SHIDROGENO O ALQUILO; R'' Y R2 SON HIDROGENO, ALQUILO, FENILO, BENCILO O CICLOALQUILO; R3 ES HIDROGENO, ALQUILO, FENILO O BENCILO; R4 ES HIDROGENO O ALQUILO; R5 ES ALQUILO, FENILO; R6 ES FENILO, ALQUILO, ALCOXIALCONOILO, AMINO, CARBOXI, O ALCOXICARBONILO.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB7846531 | 1978-11-29 | ||
GB7915737 | 1979-05-05 |
Publications (2)
Publication Number | Publication Date |
---|---|
ES8200669A1 true ES8200669A1 (es) | 1981-11-16 |
ES493859A0 ES493859A0 (es) | 1981-11-16 |
Family
ID=26269786
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES79486422A Expired ES8101589A1 (es) | 1978-11-29 | 1979-11-28 | Un procedimiento para la preparacion de nuevos compuestos iminicos heterociclicos. |
ES493859A Granted ES493859A0 (es) | 1978-11-29 | 1980-07-30 | Un procedimiento para la preparacion de nuevos compuestos iminicos heterociclicos |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES79486422A Expired ES8101589A1 (es) | 1978-11-29 | 1979-11-28 | Un procedimiento para la preparacion de nuevos compuestos iminicos heterociclicos. |
Country Status (7)
Country | Link |
---|---|
US (2) | US4250173A (es) |
EP (1) | EP0011963B1 (es) |
AU (1) | AU5263779A (es) |
DE (1) | DE2963350D1 (es) |
DK (1) | DK485979A (es) |
ES (2) | ES8101589A1 (es) |
IL (1) | IL58681A0 (es) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4414211A (en) * | 1978-09-18 | 1983-11-08 | Mcneilab, Inc. | Heterocyclic derivatives of guanidine |
EP0018107B1 (en) * | 1979-04-20 | 1982-12-22 | Beecham Group Plc | Oxazoline and thiazoline derivatives, processes for their preparation and pharmaceutical compositions containing them |
US4342764A (en) * | 1979-05-29 | 1982-08-03 | Ciba-Geigy Corporation | Guanidine compounds, pharmaceutical compositions and use |
EP0028883A3 (en) * | 1979-11-10 | 1981-06-03 | Beecham Group Plc | Benzimidazoline derivatives, processes for their preparation and pharmaceutical compositions containing them |
US4421748A (en) * | 1982-07-13 | 1983-12-20 | Trager Seymour F | Artificial tear aid |
US4704389A (en) * | 1986-03-05 | 1987-11-03 | Merrell Dow Pharmaceuticals Inc. | Aromatic omega-alkyl-imino-tetrahydro-6H-1,3-thiazin-6-one derivatives |
GB8903592D0 (en) * | 1989-02-16 | 1989-04-05 | Boots Co Plc | Therapeutic agents |
FR2728261A1 (fr) * | 1994-12-14 | 1996-06-21 | Japan Tobacco Inc | Derives de thiazine ou de thiazepine utiles comme inhibiteurs de la no-synthetase |
JP2001261652A (ja) | 2000-03-21 | 2001-09-26 | Suntory Ltd | 二置換イミノヘテロサイクリック化合物 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE1445582A1 (de) * | 1960-10-13 | 1969-06-04 | Albert Ag Chem Werke | Verfahren zur Herstellung von Derivaten des 5-Chlormethyl-oxazolidins |
US3758491A (en) * | 1972-01-07 | 1973-09-11 | Parke Davis & Co | Novel anti infective agents and means of producing the same |
DE2205744A1 (de) * | 1972-02-08 | 1973-08-09 | Thomae Gmbh Dr K | Neue durch einen guanidinylidenrest substituierte heterocyclen und verfahren zu ihrer herstellung |
CS225804B2 (cs) * | 1976-03-19 | 1984-02-13 | Mcneilab Inc | Způsob výroby heterocyklických derivátů guanidinu |
-
1979
- 1979-11-08 AU AU52637/79A patent/AU5263779A/en not_active Abandoned
- 1979-11-09 IL IL58681A patent/IL58681A0/xx unknown
- 1979-11-14 US US06/094,100 patent/US4250173A/en not_active Expired - Lifetime
- 1979-11-14 EP EP79302564A patent/EP0011963B1/en not_active Expired
- 1979-11-14 DE DE7979302564T patent/DE2963350D1/de not_active Expired
- 1979-11-15 DK DK485979A patent/DK485979A/da not_active Application Discontinuation
- 1979-11-28 ES ES79486422A patent/ES8101589A1/es not_active Expired
-
1980
- 1980-06-10 US US06/158,212 patent/US4282356A/en not_active Expired - Lifetime
- 1980-07-30 ES ES493859A patent/ES493859A0/es active Granted
Also Published As
Publication number | Publication date |
---|---|
US4250173A (en) | 1981-02-10 |
EP0011963A1 (en) | 1980-06-11 |
US4282356A (en) | 1981-08-04 |
ES486422A0 (es) | 1980-12-16 |
ES8101589A1 (es) | 1980-12-16 |
ES493859A0 (es) | 1981-11-16 |
DE2963350D1 (en) | 1982-09-02 |
EP0011963B1 (en) | 1982-07-14 |
IL58681A0 (en) | 1980-02-29 |
DK485979A (da) | 1980-05-30 |
AU5263779A (en) | 1980-05-29 |
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