ES8306370A1 - "procedimiento para la preparacion de derivados de imidazol". - Google Patents

"procedimiento para la preparacion de derivados de imidazol".

Info

Publication number
ES8306370A1
ES8306370A1 ES510795A ES510795A ES8306370A1 ES 8306370 A1 ES8306370 A1 ES 8306370A1 ES 510795 A ES510795 A ES 510795A ES 510795 A ES510795 A ES 510795A ES 8306370 A1 ES8306370 A1 ES 8306370A1
Authority
ES
Spain
Prior art keywords
hydrogen
lower alkyl
hydroxy
imidazole derivatives
acyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES510795A
Other languages
English (en)
Other versions
ES510795A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of ES510795A0 publication Critical patent/ES510795A0/es
Publication of ES8306370A1 publication Critical patent/ES8306370A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44—Iso-indoles; Hydrogenated iso-indoles
    • C07D209/48—Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/27—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by etherified hydroxy groups
    • C07C205/35—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by etherified hydroxy groups having nitro groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
    • C07C205/36—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by etherified hydroxy groups having nitro groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton to carbon atoms of the same non-condensed six-membered aromatic ring or to carbon atoms of six-membered aromatic rings being part of the same condensed ring system
    • C07C205/37—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by etherified hydroxy groups having nitro groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton to carbon atoms of the same non-condensed six-membered aromatic ring or to carbon atoms of six-membered aromatic rings being part of the same condensed ring system the oxygen atom of at least one of the etherified hydroxy groups being further bound to an acyclic carbon atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C265/00—Derivatives of isocyanic acid
    • C07C265/12—Derivatives of isocyanic acid having isocyanate groups bound to carbon atoms of six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/28—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/44—Nitrogen atoms not forming part of a nitro radical
    • C07D233/50—Nitrogen atoms not forming part of a nitro radical with carbocyclic radicals directly attached to said nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE DERIVADOS DE IMIDAZOL, DE FORMULA (I), EN LA QUE R -R PUEDEN SER VARIOS TIPOS DE RADICALES. CONSISTE EN LA REACCION DE SEPARACION DEL GRUPO ACILICO DE UN COMPUESTO DE FORMULA (II), EN LA QUE R ES ACILO Y R -R TIENEN EL MISMO SIGNIFICADO QUE EN LA FORMULA (I). LA REACCION SE LLEVA A CABO EN UN DISOLVENTE ORGANICO INERTE, EN PRESENCIA DE UN ACIDO INORGANICO, A UNA TEMPERATURA COMPRENDIDA ENTRE 0 C Y LA DE EBULLICION DE LA MEZCLA DE REACCION. ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS POR SU ACTIVIDAD ANALGESICA.
ES510795A 1980-09-10 1982-03-25 "procedimiento para la preparacion de derivados de imidazol". Expired ES8306370A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH679880 1980-09-10
CH417581 1981-06-24

Publications (2)

Publication Number Publication Date
ES510795A0 ES510795A0 (es) 1983-06-01
ES8306370A1 true ES8306370A1 (es) 1983-06-01

Family

ID=25694852

Family Applications (2)

Application Number Title Priority Date Filing Date
ES505322A Expired ES8206515A1 (es) 1980-09-10 1981-09-09 Procedimiento para la preparacion de derivados de imidazol
ES510795A Expired ES8306370A1 (es) 1980-09-10 1982-03-25 "procedimiento para la preparacion de derivados de imidazol".

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES505322A Expired ES8206515A1 (es) 1980-09-10 1981-09-09 Procedimiento para la preparacion de derivados de imidazol

Country Status (22)

Country Link
US (1) US4366160A (es)
EP (1) EP0048363B1 (es)
AR (1) AR229164A1 (es)
AU (1) AU7504281A (es)
CA (1) CA1175434A (es)
DE (2) DE3171582D1 (es)
DK (1) DK393581A (es)
ES (2) ES8206515A1 (es)
FI (1) FI812756L (es)
FR (1) FR2489822A1 (es)
GB (1) GB2083475A (es)
IL (1) IL63742A0 (es)
IT (1) IT1138510B (es)
LU (1) LU83618A1 (es)
MC (1) MC1419A1 (es)
NL (1) NL8103721A (es)
NO (1) NO813074L (es)
NZ (1) NZ198265A (es)
PH (1) PH16887A (es)
PT (1) PT73643B (es)
SE (1) SE8105297L (es)
ZW (1) ZW18881A1 (es)

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3236857A (en) * 1961-10-09 1966-02-22 Boehringer Sohn Ingelheim 2-(phenyl-amino)-1, 3-diazacyclopentene-(2) substitution products
NL123037C (es) 1963-10-04
DE1545628A1 (de) 1965-10-01 1970-06-25 Boehringer Sohn Ingelheim Verfahren zur Herstellung von blutdrucksenkend und sedativ wirksamen Derivaten des 2-(2-Halogenanilino)-1,3-diazacyclopentens-(2)
ES352379A1 (es) 1967-05-26 1969-08-01 Boehringer Sohn Ingelheim Procedimiento para la preparacion de 1,3-diazaciclopenteno-(2) sustituido en posicion 2.
DE1670230A1 (de) 1967-05-26 1971-01-21 Boehringer Sohn Ingelheim Neues Verfahren zur Herstellung von in 2-Stellung substituierten 1,3-Diazacycloalkenen(2)
DE1770872A1 (de) 1968-08-26 1972-01-13 Dresden Arzneimittel Verfahren zur Herstellung von Imidazolin-2-Derivaten
BE721781A (es) 1968-10-03 1969-04-03
DE2220906A1 (de) * 1972-04-28 1973-11-15 Boehringer Sohn Ingelheim Neue substituierte 2-phenylaminoimidazoline-(2), deren saeureadditionssalze sowie verfahren zu deren herstellung
DE2457979A1 (de) 1974-12-07 1976-06-16 Beiersdorf Ag 2-n-aryl-hydroxyamino-imidazoline-(2) und verfahren zu deren herstellung
DE2709720A1 (de) 1977-03-05 1978-09-07 Beiersdorf Ag N-substituierte 2-arylamino-imidazoline-(2), verfahren zu deren herstellung und neue hydroxylamine als zwischenprodukte
MTP837B (en) * 1977-11-07 1979-10-22 Hoffman La Roche And Co Aktien Derivatives 2 finino-imidazolidire
DE2756269A1 (de) * 1977-12-16 1979-06-21 Bayer Ag Azolylalkyl-pyridinyl-aether, verfahren zu ihrer herstellung sowie ihre verwendung als fungizide

Also Published As

Publication number Publication date
EP0048363B1 (de) 1985-07-31
FR2489822A1 (fr) 1982-03-12
EP0048363A3 (en) 1982-05-26
EP0048363A2 (de) 1982-03-31
PH16887A (en) 1984-04-02
ES510795A0 (es) 1983-06-01
ES505322A0 (es) 1982-08-16
US4366160A (en) 1982-12-28
IL63742A0 (en) 1981-12-31
GB2083475A (en) 1982-03-24
MC1419A1 (fr) 1982-10-18
IT1138510B (it) 1986-09-17
FI812756L (fi) 1982-03-11
DE3134956A1 (de) 1982-04-15
AR229164A1 (es) 1983-06-30
NZ198265A (en) 1985-02-28
IT8123655A0 (it) 1981-08-26
SE8105297L (sv) 1982-03-11
NL8103721A (nl) 1982-04-01
ZW18881A1 (en) 1982-05-05
CA1175434A (en) 1984-10-02
NO813074L (no) 1982-03-11
DE3171582D1 (en) 1985-09-05
PT73643A (en) 1981-10-01
LU83618A1 (de) 1983-06-08
ES8206515A1 (es) 1982-08-16
PT73643B (en) 1983-10-19
AU7504281A (en) 1982-03-18
DK393581A (da) 1982-03-11

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