ES8500241A1 - Procedimiento para la preparacion de derivados de imidazol - Google Patents

Procedimiento para la preparacion de derivados de imidazol

Info

Publication number
ES8500241A1
ES8500241A1 ES529174A ES529174A ES8500241A1 ES 8500241 A1 ES8500241 A1 ES 8500241A1 ES 529174 A ES529174 A ES 529174A ES 529174 A ES529174 A ES 529174A ES 8500241 A1 ES8500241 A1 ES 8500241A1
Authority
ES
Spain
Prior art keywords
imidazole derivatives
compounds
preparation
medicines containing
formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES529174A
Other languages
English (en)
Other versions
ES529174A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim Pharma GmbH and Co KG
Original Assignee
Dr Karl Thomae GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dr Karl Thomae GmbH filed Critical Dr Karl Thomae GmbH
Publication of ES8500241A1 publication Critical patent/ES8500241A1/es
Publication of ES529174A0 publication Critical patent/ES529174A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/18—Benzimidazoles; Hydrogenated benzimidazoles with aryl radicals directly attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D473/00—Heterocyclic compounds containing purine ring systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

PROCEDIMIENTO PARA LA PREPARACION DE DERIVADOS DE IMIDAZOL, DE FORMULA GENERAL (I), Y SUS SALES DE ADICION DE ACIDOS ORGANICOS O INORGANICOS FISIOLOGICAMENTE ACEPTABLES.CONSISTE EN SOMETER A UN PROCESO DE OXIDACION A UN COMPUESTO DE FORMULA GENERAL (II). EL COMPUESTO OBTENIDO SE PUEDE SOMETER, OPTATIVAMENTE, A UN PROCESO DE ALCOHOLISIS O HIDROLISIS.DE APLICACION EN EL TRATAMIENTO DE INSUFICIENCIAS CARDIACAS DE DIFERENTES GENESIS.
ES529174A 1982-07-01 1984-01-26 Procedimiento para la preparacion de derivados de imidazol Granted ES529174A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19823224512 DE3224512A1 (de) 1982-07-01 1982-07-01 Neue imidazolderivate, ihre herstellung und diese verbindungen enthaltende arzneimittel

Publications (2)

Publication Number Publication Date
ES8500241A1 true ES8500241A1 (es) 1984-10-01
ES529174A0 ES529174A0 (es) 1984-10-01

Family

ID=6167285

Family Applications (3)

Application Number Title Priority Date Filing Date
ES523709A Expired ES8500056A1 (es) 1982-07-01 1983-06-30 Procedimiento para la preparacion de derivados de imidazol.
ES529174A Granted ES529174A0 (es) 1982-07-01 1984-01-26 Procedimiento para la preparacion de derivados de imidazol
ES529175A Expired ES8500242A1 (es) 1982-07-01 1984-01-26 Procedimiento para la preparacion de derivados de imidazol

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES523709A Expired ES8500056A1 (es) 1982-07-01 1983-06-30 Procedimiento para la preparacion de derivados de imidazol.

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES529175A Expired ES8500242A1 (es) 1982-07-01 1984-01-26 Procedimiento para la preparacion de derivados de imidazol

Country Status (23)

Country Link
US (2) US4582837A (es)
EP (1) EP0098448A3 (es)
JP (1) JPS5927875A (es)
KR (1) KR840005432A (es)
AU (1) AU1642883A (es)
CS (1) CS254319B2 (es)
DD (1) DD210271A5 (es)
DE (1) DE3224512A1 (es)
DK (1) DK301383A (es)
ES (3) ES8500056A1 (es)
FI (1) FI832022L (es)
GB (1) GB2122995B (es)
GR (1) GR78598B (es)
HU (1) HU192152B (es)
IL (1) IL69111A0 (es)
NO (1) NO832356L (es)
NZ (1) NZ204766A (es)
PH (1) PH20810A (es)
PL (2) PL142880B1 (es)
PT (1) PT76968B (es)
SU (2) SU1316559A3 (es)
YU (1) YU143283A (es)
ZA (1) ZA834777B (es)

Families Citing this family (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES517193A0 (es) * 1981-11-10 1983-12-01 Wellcome Found Un procedimiento para la preparacion de nuevos derivados de imidazo (4,5-c)piridina.
US4758574A (en) * 1982-05-03 1988-07-19 Eli Lilly And Company 2-phenylimidazio (4,5-c) pyridines
DE3324115A1 (de) * 1983-07-05 1985-01-17 Dr. Karl Thomae Gmbh, 7950 Biberach Neue imidazole, ihre herstellung und diese verbindungen enthaltende arzneimittel
DE3346575A1 (de) * 1983-12-23 1985-07-04 Dr. Karl Thomae Gmbh, 7950 Biberach Neue benzimidazole, ihre herstellung und diese verbindungen enthaltende arzneimittel
GR850426B (es) * 1984-02-24 1985-06-18 Lilly Co Eli
PL144822B1 (en) * 1984-05-12 1988-07-30 Boehringer Mannheim Gmbh Method of obtaining novel pyrolobenzimidazoles
EP0178413A1 (en) * 1984-08-17 1986-04-23 Beecham Group Plc Benzimidazoles
LU85544A1 (fr) * 1984-09-19 1986-04-03 Cird Derives heterocycliques aromatiques,leur procede de preparation et leur application dans les domaines therapeutique et cosmetique
DE3445299A1 (de) * 1984-12-12 1986-06-19 Dr. Karl Thomae Gmbh, 7950 Biberach Neue imidazoderivate, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung
DE3445669A1 (de) * 1984-12-14 1986-06-19 Boehringer Mannheim Gmbh, 6800 Mannheim Neue pyrrolo-benzimidazole, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE3501497A1 (de) * 1985-01-18 1986-07-24 Boehringer Mannheim Gmbh, 6800 Mannheim Neue pyrrolo-benzimidazole, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel sowie zwischenprodukte
DE3522230A1 (de) * 1985-06-21 1987-01-02 Thomae Gmbh Dr K Neue 2-arylimidazole, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung
NZ217755A (en) * 1985-10-09 1989-08-29 Chemie Linz Ag 2-(2-thienyl)-imidazo(4,5-c)pyridine derivatives and pharmaceutical compositions
GB8804016D0 (en) * 1988-02-22 1988-03-23 Boots Co Plc Therapeutic agents
DE4027592A1 (de) * 1990-08-31 1992-03-05 Beiersdorf Ag Neue pyrrolobenzimidazole, imidazobenzoxazinone und imidazochinolone, verfahren zu ihrer herstellung und ihre verwendung sowie die verbindungen enthaltende zubereitungen
US5466704A (en) * 1991-02-26 1995-11-14 E. R. Squibb & Sons, Inc. N-substituted imidazole and benzimidazole derivatives useful as angiotenson II antagonists
FR2677020B1 (fr) * 1991-05-31 1993-08-27 Cird Galderma Composes derives de benzimidazole, leur procede de preparation et leur utilisation dans les domaines therapeutique et cosmetique.
US6911462B2 (en) * 1998-05-22 2005-06-28 Avanir Pharmaceuticals Benzimidazole compounds for regulating IgE
US6919366B2 (en) * 1998-05-22 2005-07-19 Avanir Pharmaceuticals Benzimidazole derivatives as modulators of IgE
US6867200B1 (en) 1998-12-18 2005-03-15 Axys Pharmaceuticals, Inc. (Hetero)aryl-bicyclic heteroaryl derivatives, their preparation and their use as protease inhibitors
GB9914825D0 (en) * 1999-06-24 1999-08-25 Smithkline Beecham Spa Novel compounds
TWI225488B (en) * 1999-12-21 2004-12-21 Janssen Pharmaceutica Nv Derivatives of homopiperidinyl substituted benzimidazole analogues
DE10015866A1 (de) * 2000-03-30 2001-10-11 Bayer Ag Aryl- und Heteroarylsulfonate
AU2001259707A1 (en) * 2000-06-14 2001-12-24 Warner Lambert Company 6,5-fused bicyclic heterocycles
WO2002072090A1 (en) * 2001-03-12 2002-09-19 Avanir Pharmaceuticals Benzimidazole compounds for modulating ige and inhibiting cellular proliferation
JP4416111B2 (ja) * 2002-02-14 2010-02-17 塩野義製薬株式会社 ２，３−ジアミノピリジン誘導体の製造方法
TW200304820A (en) * 2002-03-25 2003-10-16 Avanir Pharmaceuticals Use of benzimidazole analogs in the treatment of cell proliferation
TWI276631B (en) * 2002-09-12 2007-03-21 Avanir Pharmaceuticals Phenyl-aza-benzimidazole compounds for modulating IgE and inhibiting cellular proliferation
AU2003270426A1 (en) 2002-09-12 2004-04-30 Avanir Pharmaceuticals PHENYL-INDOLE COMPOUNDS FOR MODULATING IgE AND INHIBITING CELLULAR PROLIFERATION
WO2005013950A2 (en) * 2003-08-08 2005-02-17 Avanir Pharmaceuticals Selective pharmacologic inhibition of protein trafficking and related methods of treating human diseases
US7449481B2 (en) * 2004-04-13 2008-11-11 Cephalon, Inc. Thio-substituted biaryl-methanesulfinyl derivatives
JPWO2007004688A1 (ja) * 2005-07-01 2009-01-29 日本ケミファ株式会社 キサンチンオキシダーゼ阻害剤
CN101282929A (zh) * 2005-08-15 2008-10-08 Irm责任有限公司 用作tpo模拟物的化合物和组合物
WO2008067426A1 (en) * 2006-11-30 2008-06-05 Wyeth Process for the synthesis of monosulfated derivatives of substituted benzoxazoles
US7816540B2 (en) * 2007-12-21 2010-10-19 Hoffmann-La Roche Inc. Carboxyl- or hydroxyl-substituted benzimidazole derivatives
US9186361B2 (en) 2013-03-15 2015-11-17 Novartis Ag Compounds and compositions for the treatment of parasitic diseases
US9296754B2 (en) 2013-03-15 2016-03-29 Novartis Ag Compounds and compositions for the treatment of parasitic diseases
WO2014151630A2 (en) 2013-03-15 2014-09-25 Irm Llc Compounds and compositions for the treatment of parasitic diseases
HUE040254T2 (hu) 2013-12-19 2019-02-28 Novartis Ag Protozoa proteaszóma inhibitor [1,2,4]triazolo[1,5-a]pirimidinszármazékok paraziták által okozott betegségek, például leishmaniasis kezelésére
AR099677A1 (es) * 2014-03-07 2016-08-10 Sumitomo Chemical Co Compuesto heterocíclico fusionado y su uso para el control de plagas
EP3377489B1 (en) * 2015-11-16 2020-10-07 Syngenta Participations AG Pesticidally active heterocyclic derivatives with sulphur containing substituents

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3985891A (en) * 1973-02-03 1976-10-12 Boehringer Ingelheim Gmbh 2-Phenyl-imidazo (4,5-b)pyridines and salts thereof
DE2305339C3 (de) * 1973-02-03 1980-05-08 Dr. Karl Thomae Gmbh, 7950 Biberach Imidazo [4,5-b] pyridine, ihre Herstellung und ihre Verwendung als Cardiötonica
DE2927987A1 (de) * 1979-07-11 1981-02-05 Thomae Gmbh Dr K Neue 2-alkoxyphenyl-imidazo eckige klammer auf 4,5-b eckige klammer zu pyridine, deren herstellung und deren verwendung als arzneimittel
DE2927988A1 (de) * 1979-07-11 1981-02-05 Thomae Gmbh Dr K Neue 8-phenyl-purine, deren herstellung und deren verwendung als arzneimittel
JPS5721375A (en) * 1980-07-14 1982-02-04 Yamanouchi Pharmaceut Co Ltd 2,6-di-tert-butyl-4-heterocyclic substituted phenolic derivative and its preparation
DE3273461D1 (en) * 1981-08-19 1986-10-30 Merck Patent Gmbh 2-arylimidazopyridines
ES517193A0 (es) * 1981-11-10 1983-12-01 Wellcome Found Un procedimiento para la preparacion de nuevos derivados de imidazo (4,5-c)piridina.

Also Published As

Publication number Publication date
PL142880B1 (en) 1987-12-31
PT76968B (de) 1986-04-09
FI832022L (fi) 1984-01-02
SU1179924A3 (ru) 1985-09-15
US4696931A (en) 1987-09-29
KR840005432A (ko) 1984-11-12
YU143283A (en) 1986-06-30
GR78598B (es) 1984-09-27
HU192152B (en) 1987-05-28
NZ204766A (en) 1986-09-10
CS254319B2 (en) 1988-01-15
GB2122995B (en) 1986-02-12
ES529174A0 (es) 1984-10-01
PT76968A (de) 1983-07-01
SU1316559A3 (ru) 1987-06-07
PH20810A (en) 1987-04-24
ES523709A0 (es) 1984-10-01
JPS5927875A (ja) 1984-02-14
GB8317732D0 (en) 1983-08-03
US4582837A (en) 1986-04-15
FI832022A0 (fi) 1983-06-06
DK301383A (da) 1984-01-02
NO832356L (no) 1984-01-02
PL242770A1 (en) 1986-10-21
AU1642883A (en) 1984-01-05
DD210271A5 (de) 1984-06-06
GB2122995A (en) 1984-01-25
EP0098448A3 (de) 1985-04-03
ES529175A0 (es) 1984-10-01
DE3224512A1 (de) 1984-01-05
ES8500242A1 (es) 1984-10-01
ZA834777B (en) 1985-03-27
IL69111A0 (en) 1983-10-31
ES8500056A1 (es) 1984-10-01
DK301383D0 (da) 1983-06-30
EP0098448A2 (de) 1984-01-18
PL144589B1 (en) 1988-06-30

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