DE3586759D1 - Antitumor-platin-komplexe. - Google Patents

Antitumor-platin-komplexe.

Info

Publication number
DE3586759D1
DE3586759D1 DE8888105817T DE3586759T DE3586759D1 DE 3586759 D1 DE3586759 D1 DE 3586759D1 DE 8888105817 T DE8888105817 T DE 8888105817T DE 3586759 T DE3586759 T DE 3586759T DE 3586759 D1 DE3586759 D1 DE 3586759D1
Authority
DE
Germany
Prior art keywords
antitumor
platinum complexes
trans
chem
relates
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8888105817T
Other languages
English (en)
Other versions
DE3586759T2 (de
Inventor
Robert James Speer
David Philip Stewart
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bristol Myers Squibb Co
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Application granted granted Critical
Publication of DE3586759D1 publication Critical patent/DE3586759D1/de
Publication of DE3586759T2 publication Critical patent/DE3586759T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic System
    • C07F15/0006—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic System compounds of the platinum group
    • C07F15/0086—Platinum compounds
    • C07F15/0093—Platinum compounds without a metal-carbon linkage
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
DE8888105817T 1984-03-23 1985-03-22 Antitumor-platin-komplexe. Expired - Fee Related DE3586759T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/592,987 US4562275A (en) 1984-03-23 1984-03-23 Antitumor platinum complexes

Publications (2)

Publication Number Publication Date
DE3586759D1 true DE3586759D1 (de) 1992-11-19
DE3586759T2 DE3586759T2 (de) 1993-03-04

Family

ID=24372887

Family Applications (3)

Application Number Title Priority Date Filing Date
DE8888105817T Expired - Fee Related DE3586759T2 (de) 1984-03-23 1985-03-22 Antitumor-platin-komplexe.
DE8585103438T Expired - Fee Related DE3574702D1 (de) 1984-03-23 1985-03-22 Antitumor-platin-komplexe.
DE8989100585T Expired - Fee Related DE3586059D1 (de) 1984-03-23 1985-03-22 Antitumor-platin-komplexe.

Family Applications After (2)

Application Number Title Priority Date Filing Date
DE8585103438T Expired - Fee Related DE3574702D1 (de) 1984-03-23 1985-03-22 Antitumor-platin-komplexe.
DE8989100585T Expired - Fee Related DE3586059D1 (de) 1984-03-23 1985-03-22 Antitumor-platin-komplexe.

Country Status (5)

Country Link
US (2) US4562275A (de)
EP (3) EP0155705B1 (de)
JP (3) JPS60209595A (de)
AT (3) ATE76078T1 (de)
DE (3) DE3586759T2 (de)

Families Citing this family (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4739087A (en) * 1985-01-10 1988-04-19 Bristol-Myers Company Antineoplastic platinum complexes
ZA86704B (en) * 1985-02-23 1986-10-29 Asta Werke Ag Chem Fab Tumor retarding(1-benzyl-ethylenediamine9-platin(ii)-complexes
NO860509L (no) * 1985-02-23 1986-08-25 Asta Werke Ag Chem Fab Tumorhemmende (1,2-difenyl-etylendiamin)-platin(ii)-komplekser.
US4737589A (en) * 1985-08-27 1988-04-12 Nippon Kayaku Kabushiki Kaisha Platinum Complexes
JPS6310724A (ja) * 1986-03-11 1988-01-18 Chugai Pharmaceut Co Ltd 新規白金錯体を有効成分として含有する制癌剤
JPS6310725A (ja) * 1986-03-11 1988-01-18 Chugai Pharmaceut Co Ltd 新規白金錯体化合物を有効成分として含有する制癌剤
US5011959A (en) * 1986-11-17 1991-04-30 The Board Of Regents, The University Of Texas System 1,2-diaminocyclohexane-platinum complexes with antitumor activity
US5256653A (en) * 1987-02-19 1993-10-26 Henkel Kommanditgesellschaft Auf Aktien Pharmaceutical preparations containing platinum complexes/phosphonic acid liquid and processes for their use
JPS63203692A (ja) * 1987-02-19 1988-08-23 Nippon Kayaku Co Ltd 新規白金錯体
JPH02502182A (ja) 1987-02-19 1990-07-19 アスタ・メディカ・アクチエンゲゼルシャフト プラチナ錯体、その製法およびそれを含有する薬剤
EP0290169A3 (de) * 1987-05-04 1990-08-01 Engelhard Corporation Diamin-Platin-Komplexe mit Phosphoncarboxylat oder substituierten Phosphonocarboxylat-Liganden als Antitumoragenzien
US4870070A (en) * 1987-08-10 1989-09-26 American Cyanamid Company Water soluble platinum complexes of novel malonate derivatives
US4904809A (en) * 1987-09-25 1990-02-27 Ss Pharmaceutical Co., Ltd. Platinum complex
JPH0762023B2 (ja) * 1987-11-06 1995-07-05 財団法人相模中央化学研究所 白金配位化合物
WO1989004317A1 (en) * 1987-11-06 1989-05-18 Sagami Chemical Research Center Platinum (ii) complexes
JPH01165593A (ja) * 1987-12-21 1989-06-29 Toray Ind Inc 新規白金（２）錯体および悪性腫瘍治療剤
SU1685944A1 (ru) * 1988-06-06 1991-10-23 Институт Физической Химии Им.Л.В.Писаржевского Способ получени комплексного соединени платины (II) с высокомолекул рной н-ДНК из селезенки крупного рогатого скота марки А, обладающего противоопухолевой активностью
US5294430A (en) * 1988-09-12 1994-03-15 University Of Rochester Use of dithiocarbamates to treat myelosuppression
US5187193A (en) * 1988-09-12 1993-02-16 University Of Rochester Method for stimulating transplanted bone marrow cells
US5035878A (en) * 1988-09-12 1991-07-30 University Of Rochester Use of dithiocarbamates to counteract myelosuppression
US5393909A (en) * 1988-11-22 1995-02-28 Board Of Regents, The University Of Texas System Diamine platinum complexes as antitumor agents
US5225207A (en) * 1989-03-17 1993-07-06 Laboratoire Roger Bellon Complexes derived from platinum, their preparation and the pharmaceutical compositions which contain them
FR2644458B1 (fr) * 1989-03-17 1991-07-05 Bellon Labor Sa Roger Nouveaux complexes derives du platine, leur preparation et les compositions pharmaceutiques qui les contiennent
US4994591A (en) * 1989-06-02 1991-02-19 The Research Foundation Of State University Of Ny Platinum complexes derived from b-silyamines
DE69028844T2 (de) * 1989-12-12 1997-02-13 Toray Industries Neuer platin(ii)komplex und mittel für die behandlung von bösartigen tumoren
IT1238078B (it) * 1990-01-31 1993-07-05 Silvano Spinelli Cis-platino complessi con ammine e sulfinilcarbossilati chelanti
US5216352A (en) * 1990-11-29 1993-06-01 Square D Company Solid state current controlled interruption system
FR2683529B1 (fr) * 1991-11-12 1994-02-04 Bretagne Occidentale Universite Composes pharmaceutiques gem-diphosphonates analogues du cis-platine.
FR2691151A1 (fr) * 1992-05-14 1993-11-19 Bellon Labor Sa Roger Nouveaux dérivés du platine (IV), leur préparation et les compositions pharmaceutiques qui les contiennent.
CN1039588C (zh) * 1995-03-29 1998-08-26 邹娟 新的抗肿瘤铂络合物
CA2193391A1 (en) * 1995-04-25 1996-10-31 Hideki Kawai Method of producing platinum (ii) complex
US8791081B2 (en) * 1999-08-13 2014-07-29 Case Western Reserve University MGMT inhibitor combination for the treatment of neoplastic disorders
EP2266607A3 (de) 1999-10-01 2011-04-20 Immunogen, Inc. Immunokonjugate für Krebsbehandlung
AUPQ641100A0 (en) * 2000-03-23 2000-04-15 Australia Nuclear Science & Technology Organisation Methods of synthesis and use of radiolabelled platinum chemotherapeutic ag ents
WO2002013817A1 (fr) * 2000-08-11 2002-02-21 Sumitomo Pharmaceuticals Co., Ltd. Traitements contre le cancer tolerant au cisplatine
EP1332194B1 (de) 2000-10-06 2007-01-03 3M Innovative Properties Company Keramische aggregatteilchen
WO2002033020A1 (en) 2000-10-16 2002-04-25 3M Innovative Properties Company Method of making an agglomerate particles
CA2423597A1 (en) 2000-10-16 2002-04-25 3M Innovative Properties Company Method of making ceramic aggregate particles
US6645624B2 (en) 2000-11-10 2003-11-11 3M Innovative Properties Company Composite abrasive particles and method of manufacture
US7858230B2 (en) 2005-10-26 2010-12-28 The Gillette Company Battery cathodes
WO2014028653A1 (en) * 2012-08-14 2014-02-20 Northwestern University Arsenoplatin anti-cancer agents
US9499574B2 (en) 2012-08-14 2016-11-22 Northwestern University Arsenoplatin anti-cancer agents
JPWO2022065450A1 (de) 2020-09-25 2022-03-31

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4115418A (en) * 1976-09-02 1978-09-19 Government Of The United States Of America 1,2-diaminocyclohexane platinum (ii) complexes having antineoplastic activity
JPS6041077B2 (ja) * 1976-09-06 1985-09-13 喜徳 喜谷 １，２‐ジアミノシクロヘキサン異性体のシス白金（２）錯体
US4206226A (en) * 1977-08-29 1980-06-03 The United States Of America As Represented By The Department Of Health, Education And Welfare Use of 4-carboxy-phthalato-(1,2-diaminocyclohexane)-platinum(II) and alkali metal salts thereof in alleviating L1210 murine leukemia
US4137248A (en) * 1977-08-29 1979-01-30 The United States Of America As Represented By The Department Of Health, Education And Welfare Compound, 4-carboxyphthalato(1,2-diaminocyclohexane)-platinum(II) and alkali metal salts thereof
JPS5829957B2 (ja) * 1977-09-12 1983-06-25 喜徳 喜谷 新規な白金錯体
NL7810433A (nl) * 1977-10-19 1979-04-23 Johnson Matthey Co Ltd Nieuwe platinaverbindingen.
SE7903361L (sv) * 1978-04-20 1979-10-21 Johnson Matthey Co Ltd Kompositioner innehallande platina
NL7807334A (nl) * 1978-07-06 1980-01-08 Tno Platina-diaminecomplexen, werkwijze voor het bereiden daarvan, werkwijze voor het bereiden van een genees- middel met toepassing van een dergelijk platina-dia- minecomplex voor de behandeling van kanker, alsmede al- dus verkregen gevormd geneesmiddel.
JPS6034958B2 (ja) * 1978-09-02 1985-08-12 喜徳 喜谷 新規白金錯体
US4234500A (en) * 1979-03-07 1980-11-18 Engelhard Minerals & Chemicals Corporation Ethylenediamine platinum(II) and 1,2-diamino-cyclohexane platinum(II) pyrophosphate complexes
US4271085A (en) * 1979-06-20 1981-06-02 Engelhard Minerals & Chemicals Corporation Cis-platinum (II) amine lactate complexes
US4284579A (en) * 1979-07-17 1981-08-18 The United States Of America As Represented By The Of The Department Of Health & Human Services (N-Phosphonacetyl-L-aspartato)(1,2-diaminocyclchexane)platinum(II) or alkali metal salt
GR75598B (de) * 1980-04-29 1984-08-01 Sanofi Sa
JPS56154493A (en) * 1980-04-30 1981-11-30 Shionogi & Co Ltd Novel platinum complex
JPS5716895A (en) * 1980-07-05 1982-01-28 Otsuka Chem Co Ltd Platinum 2 complex and antitumor agent containing the same as active principle
JPS57123198A (en) * 1981-01-23 1982-07-31 Shionogi & Co Ltd Novel platinum complex
NL8101026A (nl) * 1981-03-03 1982-10-01 Tno Platinadiamine-complexen, werkwijze voor het bereiden daarvan, werkwijze voor het bereiden van een geneesmiddel met toepassing van een dergelijk platinadiamine-complex voor de behandeling van kanker alsmede aldus verkregen gevormd geneesmiddel.
JPS5879994A (ja) * 1981-11-06 1983-05-13 Shionogi & Co Ltd 新規アダマンタン白金錯体
JPS58124797A (ja) * 1982-01-20 1983-07-25 Shionogi & Co Ltd 新規１，２−シクロヘキサンジアミン白金錯体

Also Published As

Publication number Publication date
JPS61171494A (ja) 1986-08-02
EP0155705A3 (en) 1986-04-02
US4594418A (en) 1986-06-10
JPH0244837B2 (de) 1990-10-05
JPS61171493A (ja) 1986-08-02
JPS60209595A (ja) 1985-10-22
ATE76078T1 (de) 1992-05-15
EP0318464B1 (de) 1992-05-13
ATE48605T1 (de) 1989-12-15
US4562275A (en) 1985-12-31
DE3586759T2 (de) 1993-03-04
EP0306605B1 (de) 1992-10-14
EP0155705B1 (de) 1989-12-13
JPH0244836B2 (de) 1990-10-05
DE3586059D1 (de) 1992-06-17
EP0318464A2 (de) 1989-05-31
JPH0244838B2 (de) 1990-10-05
EP0318464A3 (en) 1989-11-15
DE3574702D1 (de) 1990-01-18
EP0155705A2 (de) 1985-09-25
ATE81506T1 (de) 1992-10-15
EP0306605A1 (de) 1989-03-15

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee