ATE48605T1 - Antitumor-platin-komplexe. - Google Patents

Antitumor-platin-komplexe.

Info

Publication number
ATE48605T1
ATE48605T1 AT85103438T AT85103438T ATE48605T1 AT E48605 T1 ATE48605 T1 AT E48605T1 AT 85103438 T AT85103438 T AT 85103438T AT 85103438 T AT85103438 T AT 85103438T AT E48605 T1 ATE48605 T1 AT E48605T1
Authority
AT
Austria
Prior art keywords
platinum complexes
antitumor platinum
trans
chem
relates
Prior art date
Application number
AT85103438T
Other languages
English (en)
Inventor
Robert James Speer
David Philip Stewart
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Application granted granted Critical
Publication of ATE48605T1 publication Critical patent/ATE48605T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • C07F15/0006—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table compounds of the platinum group
    • C07F15/0086—Platinum compounds
    • C07F15/0093—Platinum compounds without a metal-carbon linkage
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Saccharide Compounds (AREA)
AT85103438T 1984-03-23 1985-03-22 Antitumor-platin-komplexe. ATE48605T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/592,987 US4562275A (en) 1984-03-23 1984-03-23 Antitumor platinum complexes
EP85103438A EP0155705B1 (de) 1984-03-23 1985-03-22 Antitumor-Platin-Komplexe

Publications (1)

Publication Number Publication Date
ATE48605T1 true ATE48605T1 (de) 1989-12-15

Family

ID=24372887

Family Applications (3)

Application Number Title Priority Date Filing Date
AT88105817T ATE81506T1 (de) 1984-03-23 1985-03-22 Antitumor-platin-komplexe.
AT85103438T ATE48605T1 (de) 1984-03-23 1985-03-22 Antitumor-platin-komplexe.
AT89100585T ATE76078T1 (de) 1984-03-23 1985-03-22 Antitumor-platin-komplexe.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AT88105817T ATE81506T1 (de) 1984-03-23 1985-03-22 Antitumor-platin-komplexe.

Family Applications After (1)

Application Number Title Priority Date Filing Date
AT89100585T ATE76078T1 (de) 1984-03-23 1985-03-22 Antitumor-platin-komplexe.

Country Status (5)

Country Link
US (2) US4562275A (de)
EP (3) EP0306605B1 (de)
JP (3) JPS60209595A (de)
AT (3) ATE81506T1 (de)
DE (3) DE3586059D1 (de)

Families Citing this family (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4739087A (en) * 1985-01-10 1988-04-19 Bristol-Myers Company Antineoplastic platinum complexes
ZA86704B (en) * 1985-02-23 1986-10-29 Asta Werke Ag Chem Fab Tumor retarding(1-benzyl-ethylenediamine9-platin(ii)-complexes
NO860509L (no) * 1985-02-23 1986-08-25 Asta Werke Ag Chem Fab Tumorhemmende (1,2-difenyl-etylendiamin)-platin(ii)-komplekser.
US4737589A (en) * 1985-08-27 1988-04-12 Nippon Kayaku Kabushiki Kaisha Platinum Complexes
JPS6310724A (ja) * 1986-03-11 1988-01-18 Chugai Pharmaceut Co Ltd 新規白金錯体を有効成分として含有する制癌剤
JPS6310725A (ja) * 1986-03-11 1988-01-18 Chugai Pharmaceut Co Ltd 新規白金錯体化合物を有効成分として含有する制癌剤
US5011959A (en) * 1986-11-17 1991-04-30 The Board Of Regents, The University Of Texas System 1,2-diaminocyclohexane-platinum complexes with antitumor activity
JPS63203692A (ja) * 1987-02-19 1988-08-23 Nippon Kayaku Co Ltd 新規白金錯体
JPH02502182A (ja) 1987-02-19 1990-07-19 アスタ・メディカ・アクチエンゲゼルシャフト プラチナ錯体、その製法およびそれを含有する薬剤
US5256653A (en) * 1987-02-19 1993-10-26 Henkel Kommanditgesellschaft Auf Aktien Pharmaceutical preparations containing platinum complexes/phosphonic acid liquid and processes for their use
EP0290169A3 (de) * 1987-05-04 1990-08-01 Engelhard Corporation Diamin-Platin-Komplexe mit Phosphoncarboxylat oder substituierten Phosphonocarboxylat-Liganden als Antitumoragenzien
US4870070A (en) * 1987-08-10 1989-09-26 American Cyanamid Company Water soluble platinum complexes of novel malonate derivatives
US4904809A (en) * 1987-09-25 1990-02-27 Ss Pharmaceutical Co., Ltd. Platinum complex
JPH0762023B2 (ja) * 1987-11-06 1995-07-05 財団法人相模中央化学研究所 白金配位化合物
WO1989004317A1 (en) * 1987-11-06 1989-05-18 Sagami Chemical Research Center Platinum (ii) complexes
JPH01165593A (ja) * 1987-12-21 1989-06-29 Toray Ind Inc 新規白金（２）錯体および悪性腫瘍治療剤
SU1685944A1 (ru) * 1988-06-06 1991-10-23 Институт Физической Химии Им.Л.В.Писаржевского Способ получени комплексного соединени платины (II) с высокомолекул рной н-ДНК из селезенки крупного рогатого скота марки А, обладающего противоопухолевой активностью
US5035878A (en) * 1988-09-12 1991-07-30 University Of Rochester Use of dithiocarbamates to counteract myelosuppression
US5294430A (en) * 1988-09-12 1994-03-15 University Of Rochester Use of dithiocarbamates to treat myelosuppression
US5187193A (en) * 1988-09-12 1993-02-16 University Of Rochester Method for stimulating transplanted bone marrow cells
US5393909A (en) * 1988-11-22 1995-02-28 Board Of Regents, The University Of Texas System Diamine platinum complexes as antitumor agents
US5225207A (en) * 1989-03-17 1993-07-06 Laboratoire Roger Bellon Complexes derived from platinum, their preparation and the pharmaceutical compositions which contain them
FR2644458B1 (fr) * 1989-03-17 1991-07-05 Bellon Labor Sa Roger Nouveaux complexes derives du platine, leur preparation et les compositions pharmaceutiques qui les contiennent
US4994591A (en) * 1989-06-02 1991-02-19 The Research Foundation Of State University Of Ny Platinum complexes derived from b-silyamines
AU639804B2 (en) * 1989-12-12 1993-08-05 Toray Industries, Inc. Novel platinum (ii) complex and drug for treating malignant tumor
IT1238078B (it) * 1990-01-31 1993-07-05 Silvano Spinelli Cis-platino complessi con ammine e sulfinilcarbossilati chelanti
US5216352A (en) * 1990-11-29 1993-06-01 Square D Company Solid state current controlled interruption system
FR2683529B1 (fr) * 1991-11-12 1994-02-04 Bretagne Occidentale Universite Composes pharmaceutiques gem-diphosphonates analogues du cis-platine.
FR2691151A1 (fr) * 1992-05-14 1993-11-19 Bellon Labor Sa Roger Nouveaux dérivés du platine (IV), leur préparation et les compositions pharmaceutiques qui les contiennent.
CN1039588C (zh) * 1995-03-29 1998-08-26 邹娟 新的抗肿瘤铂络合物
EP0768315A4 (de) * 1995-04-25 1998-12-30 Toray Industries Verfahren zur herstellung von platin(ii)-komplexen
WO2008109417A1 (en) * 2007-03-02 2008-09-12 Case Western Reserve University Mgmt inhibitor combinations for the treatment of neoplastic disorders
EP1229934B1 (de) 1999-10-01 2014-03-05 Immunogen, Inc. Zusammensetzungen und verfahren zur behandlung von krebs mittels immunkonjugaten und chemotherapeutischen agenzien
AUPQ641100A0 (en) * 2000-03-23 2000-04-15 Australia Nuclear Science & Technology Organisation Methods of synthesis and use of radiolabelled platinum chemotherapeutic ag ents
US7253209B2 (en) * 2000-08-11 2007-08-07 Dainippon Sumitomo Pharma Co., Ltd. Remedies for cisplatin-tolerant cancer
EP1332194B1 (de) 2000-10-06 2007-01-03 3M Innovative Properties Company Keramische aggregatteilchen
AU2002211508A1 (en) 2000-10-16 2002-04-29 3M Innovative Properties Company Method of making an agglomerate particles
WO2002033019A1 (en) 2000-10-16 2002-04-25 3M Innovative Properties Company Method of making ceramic aggregate particles
US6645624B2 (en) 2000-11-10 2003-11-11 3M Innovative Properties Company Composite abrasive particles and method of manufacture
US7858230B2 (en) 2005-10-26 2010-12-28 The Gillette Company Battery cathodes
US9499574B2 (en) 2012-08-14 2016-11-22 Northwestern University Arsenoplatin anti-cancer agents
WO2014028653A1 (en) 2012-08-14 2014-02-20 Northwestern University Arsenoplatin anti-cancer agents
EP4220769A1 (de) 2020-09-25 2023-08-02 Tohoku University Negativelektrodenmischung für lithium-ionen-sekundärbatterie und lithium-ionen-sekundärbatterie

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4115418A (en) * 1976-09-02 1978-09-19 Government Of The United States Of America 1,2-diaminocyclohexane platinum (ii) complexes having antineoplastic activity
JPS6041077B2 (ja) * 1976-09-06 1985-09-13 喜徳 喜谷 １，２‐ジアミノシクロヘキサン異性体のシス白金（２）錯体
US4206226A (en) * 1977-08-29 1980-06-03 The United States Of America As Represented By The Department Of Health, Education And Welfare Use of 4-carboxy-phthalato-(1,2-diaminocyclohexane)-platinum(II) and alkali metal salts thereof in alleviating L1210 murine leukemia
US4137248A (en) * 1977-08-29 1979-01-30 The United States Of America As Represented By The Department Of Health, Education And Welfare Compound, 4-carboxyphthalato(1,2-diaminocyclohexane)-platinum(II) and alkali metal salts thereof
JPS5829957B2 (ja) * 1977-09-12 1983-06-25 喜徳 喜谷 新規な白金錯体
US4203912A (en) * 1977-10-19 1980-05-20 Johnson, Matthey & Co., Limited Compositions containing platinum
SE7903361L (sv) * 1978-04-20 1979-10-21 Johnson Matthey Co Ltd Kompositioner innehallande platina
NL7807334A (nl) * 1978-07-06 1980-01-08 Tno Platina-diaminecomplexen, werkwijze voor het bereiden daarvan, werkwijze voor het bereiden van een genees- middel met toepassing van een dergelijk platina-dia- minecomplex voor de behandeling van kanker, alsmede al- dus verkregen gevormd geneesmiddel.
JPS6034958B2 (ja) * 1978-09-02 1985-08-12 喜徳 喜谷 新規白金錯体
US4234500A (en) * 1979-03-07 1980-11-18 Engelhard Minerals & Chemicals Corporation Ethylenediamine platinum(II) and 1,2-diamino-cyclohexane platinum(II) pyrophosphate complexes
US4271085A (en) * 1979-06-20 1981-06-02 Engelhard Minerals & Chemicals Corporation Cis-platinum (II) amine lactate complexes
US4284579A (en) * 1979-07-17 1981-08-18 The United States Of America As Represented By The Of The Department Of Health & Human Services (N-Phosphonacetyl-L-aspartato)(1,2-diaminocyclchexane)platinum(II) or alkali metal salt
GR75598B (de) * 1980-04-29 1984-08-01 Sanofi Sa
JPS56154493A (en) * 1980-04-30 1981-11-30 Shionogi & Co Ltd Novel platinum complex
JPS5716895A (en) * 1980-07-05 1982-01-28 Otsuka Chem Co Ltd Platinum 2 complex and antitumor agent containing the same as active principle
JPS57123198A (en) * 1981-01-23 1982-07-31 Shionogi & Co Ltd Novel platinum complex
NL8101026A (nl) * 1981-03-03 1982-10-01 Tno Platinadiamine-complexen, werkwijze voor het bereiden daarvan, werkwijze voor het bereiden van een geneesmiddel met toepassing van een dergelijk platinadiamine-complex voor de behandeling van kanker alsmede aldus verkregen gevormd geneesmiddel.
JPS5879994A (ja) * 1981-11-06 1983-05-13 Shionogi & Co Ltd 新規アダマンタン白金錯体
JPS58124797A (ja) * 1982-01-20 1983-07-25 Shionogi & Co Ltd 新規１，２−シクロヘキサンジアミン白金錯体

Also Published As

Publication number Publication date
JPH0244836B2 (de) 1990-10-05
DE3574702D1 (de) 1990-01-18
US4594418A (en) 1986-06-10
EP0155705A2 (de) 1985-09-25
EP0155705B1 (de) 1989-12-13
EP0306605B1 (de) 1992-10-14
EP0318464B1 (de) 1992-05-13
JPS61171494A (ja) 1986-08-02
EP0318464A2 (de) 1989-05-31
EP0318464A3 (en) 1989-11-15
JPH0244838B2 (de) 1990-10-05
DE3586759D1 (de) 1992-11-19
ATE76078T1 (de) 1992-05-15
US4562275A (en) 1985-12-31
DE3586059D1 (de) 1992-06-17
JPH0244837B2 (de) 1990-10-05
EP0155705A3 (en) 1986-04-02
ATE81506T1 (de) 1992-10-15
EP0306605A1 (de) 1989-03-15
JPS60209595A (ja) 1985-10-22
JPS61171493A (ja) 1986-08-02
DE3586759T2 (de) 1993-03-04

Similar Documents

Publication Publication Date Title
DE3574702D1 (de) Antitumor-platin-komplexe.
FI901530A0 (fi) Menetelmä immunomoduloivien atsaspiraanien valmistamiseksi
ES8307806A1 (es) "procedimiento para la preparacion de 1,2-a piridinas y pirazinas".
ES8706713A1 (es) Un procedimiento para preparar derivados de 4'-desmetil-4-epipodofilotoxina
DK0559079T3 (da) Substituerede aminophosphonatderivater, fremgangsmåde til fremstilling deraf samt farmaceutiske præparater indeholdende derivaterne
MY105538A (en) Derivatives of thieno-triazolo-diazepine, a preparation process of the same and therapeutic compositions containing them.
NO894349L (no) Tienopyridin-type mevalonolaktoner.
DE3777319D1 (de) Verbindung auf basis von chinolin, verfahren zur herstellung und antikrebsmittel enthaltend diese verbindung als pharmakologisch wirksame komponente.
DE3477488D1 (en) Polymethoxybenzyl piperazine derivatives, processes for their preparation and pharmaceutical compositions containing said derivatives
PT78315A (en) Process for preparing penems and pharmaceutical preparations containing them
ES8609319A1 (es) Procedimiento de preparacion de nuevas fenil-naftiridinas.
ES8207507A1 (es) Un procedimiento para la preparacion de un compuesto de platino.
GR3006438T3 (de)
AU568694B2 (en) N-benzyl-n-phenyl-b-pyrrolidinyl-f-isobutoxy-propylamine
AU623986B2 (en) Platinum complexes and antitumor agents containing them as an active ingredient
AU581101B2 (en) Anti-tumour platinum complexes, their preparation and their use
ES2000614A6 (es) Procedimiento de obtencion de nuevos complejos de platino (ii) derivados del 2,3-dimercapto-2-butene-dinitrilato (2-)-s,s'"
DE3663664D1 (en) Compounds having antiplatelet aggregation activity, a process for the preparation thereof and pharmaceutical compositions containing them
ES8801291A1 (es) Un procedimiento para la preparacion de nuevos derivados de beta-lactama.
DE3461189D1 (en) New 3-alkylthio-2-o-carbamoyl-propane-1.2-diol-1-o-phosphocholines, and processes for their preparation

Legal Events

Date Code Title Description
EEIH Change in the person of patent owner
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee