ATE76078T1 - Antitumor-platin-komplexe. - Google Patents

Antitumor-platin-komplexe.

Info

Publication number
ATE76078T1
ATE76078T1 AT89100585T AT89100585T ATE76078T1 AT E76078 T1 ATE76078 T1 AT E76078T1 AT 89100585 T AT89100585 T AT 89100585T AT 89100585 T AT89100585 T AT 89100585T AT E76078 T1 ATE76078 T1 AT E76078T1
Authority
AT
Austria
Prior art keywords
platinum complexes
antitumor platinum
trans
chem
relates
Prior art date
Application number
AT89100585T
Other languages
English (en)
Inventor
Robert James Speer
David Philip Stewart
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Application granted granted Critical
Publication of ATE76078T1 publication Critical patent/ATE76078T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • C07F15/0006—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table compounds of the platinum group
    • C07F15/0086—Platinum compounds
    • C07F15/0093—Platinum compounds without a metal-carbon linkage
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Saccharide Compounds (AREA)
AT89100585T 1984-03-23 1985-03-22 Antitumor-platin-komplexe. ATE76078T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/592,987 US4562275A (en) 1984-03-23 1984-03-23 Antitumor platinum complexes
EP89100585A EP0318464B1 (de) 1984-03-23 1985-03-22 Antitumor-Platin-Komplexe

Publications (1)

Publication Number Publication Date
ATE76078T1 true ATE76078T1 (de) 1992-05-15

Family

ID=24372887

Family Applications (3)

Application Number Title Priority Date Filing Date
AT85103438T ATE48605T1 (de) 1984-03-23 1985-03-22 Antitumor-platin-komplexe.
AT89100585T ATE76078T1 (de) 1984-03-23 1985-03-22 Antitumor-platin-komplexe.
AT88105817T ATE81506T1 (de) 1984-03-23 1985-03-22 Antitumor-platin-komplexe.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
AT85103438T ATE48605T1 (de) 1984-03-23 1985-03-22 Antitumor-platin-komplexe.

Family Applications After (1)

Application Number Title Priority Date Filing Date
AT88105817T ATE81506T1 (de) 1984-03-23 1985-03-22 Antitumor-platin-komplexe.

Country Status (5)

Country Link
US (2) US4562275A (de)
EP (3) EP0318464B1 (de)
JP (3) JPS60209595A (de)
AT (3) ATE48605T1 (de)
DE (3) DE3586759T2 (de)

Families Citing this family (43)

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US4739087A (en) * 1985-01-10 1988-04-19 Bristol-Myers Company Antineoplastic platinum complexes
ZA86704B (en) * 1985-02-23 1986-10-29 Asta Werke Ag Chem Fab Tumor retarding(1-benzyl-ethylenediamine9-platin(ii)-complexes
NO860509L (no) * 1985-02-23 1986-08-25 Asta Werke Ag Chem Fab Tumorhemmende (1,2-difenyl-etylendiamin)-platin(ii)-komplekser.
US4737589A (en) * 1985-08-27 1988-04-12 Nippon Kayaku Kabushiki Kaisha Platinum Complexes
JPS6310724A (ja) * 1986-03-11 1988-01-18 Chugai Pharmaceut Co Ltd 新規白金錯体を有効成分として含有する制癌剤
JPS6310725A (ja) * 1986-03-11 1988-01-18 Chugai Pharmaceut Co Ltd 新規白金錯体化合物を有効成分として含有する制癌剤
US5011959A (en) * 1986-11-17 1991-04-30 The Board Of Regents, The University Of Texas System 1,2-diaminocyclohexane-platinum complexes with antitumor activity
JPS63203692A (ja) * 1987-02-19 1988-08-23 Nippon Kayaku Co Ltd 新規白金錯体
US5256653A (en) * 1987-02-19 1993-10-26 Henkel Kommanditgesellschaft Auf Aktien Pharmaceutical preparations containing platinum complexes/phosphonic acid liquid and processes for their use
DE3889327D1 (de) 1987-02-19 1994-06-01 Asta Medica Ag Platinkomplexe enthaltende arzneimittel.
EP0290169A3 (de) * 1987-05-04 1990-08-01 Engelhard Corporation Diamin-Platin-Komplexe mit Phosphoncarboxylat oder substituierten Phosphonocarboxylat-Liganden als Antitumoragenzien
US4870070A (en) * 1987-08-10 1989-09-26 American Cyanamid Company Water soluble platinum complexes of novel malonate derivatives
US4904809A (en) * 1987-09-25 1990-02-27 Ss Pharmaceutical Co., Ltd. Platinum complex
WO1989004317A1 (en) * 1987-11-06 1989-05-18 Sagami Chemical Research Center Platinum (ii) complexes
JPH0762023B2 (ja) * 1987-11-06 1995-07-05 財団法人相模中央化学研究所 白金配位化合物
JPH01165593A (ja) * 1987-12-21 1989-06-29 Toray Ind Inc 新規白金（２）錯体および悪性腫瘍治療剤
SU1685944A1 (ru) * 1988-06-06 1991-10-23 Институт Физической Химии Им.Л.В.Писаржевского Способ получени комплексного соединени платины (II) с высокомолекул рной н-ДНК из селезенки крупного рогатого скота марки А, обладающего противоопухолевой активностью
US5294430A (en) * 1988-09-12 1994-03-15 University Of Rochester Use of dithiocarbamates to treat myelosuppression
US5035878A (en) * 1988-09-12 1991-07-30 University Of Rochester Use of dithiocarbamates to counteract myelosuppression
US5187193A (en) * 1988-09-12 1993-02-16 University Of Rochester Method for stimulating transplanted bone marrow cells
US5393909A (en) * 1988-11-22 1995-02-28 Board Of Regents, The University Of Texas System Diamine platinum complexes as antitumor agents
FR2644458B1 (fr) * 1989-03-17 1991-07-05 Bellon Labor Sa Roger Nouveaux complexes derives du platine, leur preparation et les compositions pharmaceutiques qui les contiennent
US5225207A (en) * 1989-03-17 1993-07-06 Laboratoire Roger Bellon Complexes derived from platinum, their preparation and the pharmaceutical compositions which contain them
US4994591A (en) * 1989-06-02 1991-02-19 The Research Foundation Of State University Of Ny Platinum complexes derived from b-silyamines
ES2091904T3 (es) * 1989-12-12 1996-11-16 Toray Industries Nuevo complejo de platino (ii) y agente para el tratamiento de tumores malignos.
IT1238078B (it) * 1990-01-31 1993-07-05 Silvano Spinelli Cis-platino complessi con ammine e sulfinilcarbossilati chelanti
US5216352A (en) * 1990-11-29 1993-06-01 Square D Company Solid state current controlled interruption system
FR2683529B1 (fr) * 1991-11-12 1994-02-04 Bretagne Occidentale Universite Composes pharmaceutiques gem-diphosphonates analogues du cis-platine.
FR2691151A1 (fr) * 1992-05-14 1993-11-19 Bellon Labor Sa Roger Nouveaux dérivés du platine (IV), leur préparation et les compositions pharmaceutiques qui les contiennent.
CN1039588C (zh) * 1995-03-29 1998-08-26 邹娟 新的抗肿瘤铂络合物
CA2193391A1 (en) * 1995-04-25 1996-10-31 Hideki Kawai Method of producing platinum (ii) complex
US8791081B2 (en) * 1999-08-13 2014-07-29 Case Western Reserve University MGMT inhibitor combination for the treatment of neoplastic disorders
EP2266607A3 (de) 1999-10-01 2011-04-20 Immunogen, Inc. Immunokonjugate für Krebsbehandlung
AUPQ641100A0 (en) * 2000-03-23 2000-04-15 Australia Nuclear Science & Technology Organisation Methods of synthesis and use of radiolabelled platinum chemotherapeutic ag ents
AU2001277711A1 (en) * 2000-08-11 2002-02-25 Sumitomo Pharmaceuticals Co. Ltd. Remedies for cisplatin-tolerant cancer
US20020066233A1 (en) 2000-10-06 2002-06-06 3M Innovative Properties Company Ceramic aggregate particles
AU2001296702A1 (en) 2000-10-16 2002-04-29 3M Innovative Properties Company Method of making ceramic aggregate particles
ATE382671T1 (de) 2000-10-16 2008-01-15 3M Innovative Properties Co Verfahren zur herstellung von agglomeratteilchen
US6645624B2 (en) 2000-11-10 2003-11-11 3M Innovative Properties Company Composite abrasive particles and method of manufacture
US7858230B2 (en) 2005-10-26 2010-12-28 The Gillette Company Battery cathodes
US9499574B2 (en) 2012-08-14 2016-11-22 Northwestern University Arsenoplatin anti-cancer agents
WO2014028653A1 (en) 2012-08-14 2014-02-20 Northwestern University Arsenoplatin anti-cancer agents
US20230343941A1 (en) 2020-09-25 2023-10-26 Tohoku University Lithium-ion secondary battery negative electrode mixture and lithium-ion secondary battery

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4115418A (en) * 1976-09-02 1978-09-19 Government Of The United States Of America 1,2-diaminocyclohexane platinum (ii) complexes having antineoplastic activity
JPS6041077B2 (ja) * 1976-09-06 1985-09-13 喜徳 喜谷 １，２‐ジアミノシクロヘキサン異性体のシス白金（２）錯体
US4206226A (en) * 1977-08-29 1980-06-03 The United States Of America As Represented By The Department Of Health, Education And Welfare Use of 4-carboxy-phthalato-(1,2-diaminocyclohexane)-platinum(II) and alkali metal salts thereof in alleviating L1210 murine leukemia
US4137248A (en) * 1977-08-29 1979-01-30 The United States Of America As Represented By The Department Of Health, Education And Welfare Compound, 4-carboxyphthalato(1,2-diaminocyclohexane)-platinum(II) and alkali metal salts thereof
JPS5829957B2 (ja) * 1977-09-12 1983-06-25 喜徳 喜谷 新規な白金錯体
DE2845371A1 (de) * 1977-10-19 1979-04-26 Johnson Matthey Co Ltd Platinkomplexverbindung, pharmazeutische stoffzusammensetzung mit einer solchen verbindung und deren anwendung
SE7903361L (sv) * 1978-04-20 1979-10-21 Johnson Matthey Co Ltd Kompositioner innehallande platina
NL7807334A (nl) * 1978-07-06 1980-01-08 Tno Platina-diaminecomplexen, werkwijze voor het bereiden daarvan, werkwijze voor het bereiden van een genees- middel met toepassing van een dergelijk platina-dia- minecomplex voor de behandeling van kanker, alsmede al- dus verkregen gevormd geneesmiddel.
JPS6034958B2 (ja) * 1978-09-02 1985-08-12 喜徳 喜谷 新規白金錯体
US4234500A (en) * 1979-03-07 1980-11-18 Engelhard Minerals & Chemicals Corporation Ethylenediamine platinum(II) and 1,2-diamino-cyclohexane platinum(II) pyrophosphate complexes
US4271085A (en) * 1979-06-20 1981-06-02 Engelhard Minerals & Chemicals Corporation Cis-platinum (II) amine lactate complexes
US4284579A (en) * 1979-07-17 1981-08-18 The United States Of America As Represented By The Of The Department Of Health & Human Services (N-Phosphonacetyl-L-aspartato)(1,2-diaminocyclchexane)platinum(II) or alkali metal salt
GR75598B (de) * 1980-04-29 1984-08-01 Sanofi Sa
JPS56154493A (en) * 1980-04-30 1981-11-30 Shionogi & Co Ltd Novel platinum complex
JPS5716895A (en) * 1980-07-05 1982-01-28 Otsuka Chem Co Ltd Platinum 2 complex and antitumor agent containing the same as active principle
JPS57123198A (en) * 1981-01-23 1982-07-31 Shionogi & Co Ltd Novel platinum complex
NL8101026A (nl) * 1981-03-03 1982-10-01 Tno Platinadiamine-complexen, werkwijze voor het bereiden daarvan, werkwijze voor het bereiden van een geneesmiddel met toepassing van een dergelijk platinadiamine-complex voor de behandeling van kanker alsmede aldus verkregen gevormd geneesmiddel.
JPS5879994A (ja) * 1981-11-06 1983-05-13 Shionogi & Co Ltd 新規アダマンタン白金錯体
JPS58124797A (ja) * 1982-01-20 1983-07-25 Shionogi & Co Ltd 新規１，２−シクロヘキサンジアミン白金錯体

Also Published As

Publication number Publication date
EP0155705B1 (de) 1989-12-13
US4594418A (en) 1986-06-10
EP0318464B1 (de) 1992-05-13
EP0155705A2 (de) 1985-09-25
EP0318464A3 (en) 1989-11-15
EP0155705A3 (en) 1986-04-02
ATE81506T1 (de) 1992-10-15
JPH0244836B2 (de) 1990-10-05
JPS61171493A (ja) 1986-08-02
DE3586759T2 (de) 1993-03-04
US4562275A (en) 1985-12-31
EP0318464A2 (de) 1989-05-31
DE3586759D1 (de) 1992-11-19
JPH0244838B2 (de) 1990-10-05
DE3586059D1 (de) 1992-06-17
JPH0244837B2 (de) 1990-10-05
EP0306605A1 (de) 1989-03-15
EP0306605B1 (de) 1992-10-14
ATE48605T1 (de) 1989-12-15
DE3574702D1 (de) 1990-01-18
JPS60209595A (ja) 1985-10-22
JPS61171494A (ja) 1986-08-02

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee