DE3777319D1 - Verbindung auf basis von chinolin, verfahren zur herstellung und antikrebsmittel enthaltend diese verbindung als pharmakologisch wirksame komponente. - Google Patents

Verbindung auf basis von chinolin, verfahren zur herstellung und antikrebsmittel enthaltend diese verbindung als pharmakologisch wirksame komponente.

Info

Publication number
DE3777319D1
DE3777319D1 DE8787115032T DE3777319T DE3777319D1 DE 3777319 D1 DE3777319 D1 DE 3777319D1 DE 8787115032 T DE8787115032 T DE 8787115032T DE 3777319 T DE3777319 T DE 3777319T DE 3777319 D1 DE3777319 D1 DE 3777319D1
Authority
DE
Germany
Prior art keywords
connection
chinoline
production
agent containing
effective component
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8787115032T
Other languages
English (en)
Inventor
Mastoshi Yamato
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
KANTO ISHI PHARMA CO Ltd
Mect Corp
Original Assignee
KANTO ISHI PHARMA CO Ltd
Mect Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by KANTO ISHI PHARMA CO Ltd, Mect Corp filed Critical KANTO ISHI PHARMA CO Ltd
Application granted granted Critical
Publication of DE3777319D1 publication Critical patent/DE3777319D1/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/04—Ortho- or peri-condensed ring systems
    • C07D221/18—Ring systems of four or more rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
DE8787115032T 1986-10-17 1987-10-14 Verbindung auf basis von chinolin, verfahren zur herstellung und antikrebsmittel enthaltend diese verbindung als pharmakologisch wirksame komponente. Expired - Fee Related DE3777319D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP61246776A JPS63101369A (ja) 1986-10-17 1986-10-17 インデノキノリン系化合物、その製造法及びその化合物を有効成分とする抗癌剤

Publications (1)

Publication Number Publication Date
DE3777319D1 true DE3777319D1 (de) 1992-04-16

Family

ID=17153489

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8787115032T Expired - Fee Related DE3777319D1 (de) 1986-10-17 1987-10-14 Verbindung auf basis von chinolin, verfahren zur herstellung und antikrebsmittel enthaltend diese verbindung als pharmakologisch wirksame komponente.

Country Status (12)

Country Link
US (1) US4826850A (de)
EP (1) EP0264124B1 (de)
JP (1) JPS63101369A (de)
KR (1) KR900003499B1 (de)
CN (1) CN1009826B (de)
AT (1) ATE73447T1 (de)
AU (1) AU598878B2 (de)
DE (1) DE3777319D1 (de)
DK (1) DK543987A (de)
ES (1) ES2033279T3 (de)
GR (1) GR3004353T3 (de)
NZ (1) NZ222185A (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH01228965A (ja) * 1988-03-10 1989-09-12 Mect Corp 縮合キノリン系化合物及び縮合アクリジン系化合物、それらの製造法ならびにそれらの化合物を有効成分とする抗癌剤
JPH0692410B2 (ja) * 1988-08-30 1994-11-16 キッセイ薬品工業株式会社 新規なベンゾフロキノリン誘導体
US5217961A (en) * 1988-12-27 1993-06-08 Mect Corporation Condensed quinoline system N-glycosides
JPH02256667A (ja) * 1988-12-27 1990-10-17 Masatoshi Yamato 縮合キノリン系化合物およびその製造方法
AU640135B2 (en) * 1990-03-20 1993-08-19 Wellcome Foundation Limited, The Hetero polycyclic biocidal compounds and their use in medicine
US5223506A (en) * 1991-06-04 1993-06-29 Glaxo Inc. Cyclic antitumor compounds
US5681958A (en) * 1995-06-07 1997-10-28 Shaman Pharmaceuticals, Inc. Cryptolepine analogs with hypoglycemic activity
US5917052A (en) * 1994-09-28 1999-06-29 Shaman Pharmaceuticals, Inc. Hypoglycemic agent from cryptolepis
JP3141148B2 (ja) * 1995-08-08 2001-03-05 大鵬薬品工業株式会社 縮合インダン誘導体及びその塩
US5741926A (en) * 1997-02-12 1998-04-21 Shaman Pharmaceuticals, Inc. Aniline derivatives having antihyperglycemic activity
CN105622508B (zh) * 2015-12-22 2018-08-21 广西师范大学 一种新的[1,2,b]茚并喹啉类衍生物及其制备方法和在抗肿瘤药物中的应用
CN107325110B (zh) * 2017-07-21 2019-06-11 太原理工大学 一种四元杂环苯并噻吩并喹啉化合物及其合成方法
CN110256451B (zh) * 2019-07-15 2021-09-03 河南省科学院化学研究所有限公司 一种苯并呋喃并[2,3-b]喹啉衍生物的合成方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ200715A (en) * 1982-05-24 1986-06-11 New Zealand Dev Finance Acridine derivatives and pharmaceutical compositions containing such

Also Published As

Publication number Publication date
JPS63101369A (ja) 1988-05-06
DK543987D0 (da) 1987-10-16
ES2033279T3 (es) 1993-03-16
KR900003499B1 (ko) 1990-05-21
EP0264124A1 (de) 1988-04-20
EP0264124B1 (de) 1992-03-11
US4826850A (en) 1989-05-02
CN1009826B (zh) 1990-10-03
KR880005136A (ko) 1988-06-28
ATE73447T1 (de) 1992-03-15
AU7987587A (en) 1988-04-21
NZ222185A (en) 1990-07-26
AU598878B2 (en) 1990-07-05
GR3004353T3 (de) 1993-03-31
CN87106996A (zh) 1988-06-15
DK543987A (da) 1988-04-18

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee