ES8801291A1 - Un procedimiento para la preparacion de nuevos derivados de beta-lactama. - Google Patents
Un procedimiento para la preparacion de nuevos derivados de beta-lactama.Info
- Publication number
- ES8801291A1 ES8801291A1 ES556468A ES556468A ES8801291A1 ES 8801291 A1 ES8801291 A1 ES 8801291A1 ES 556468 A ES556468 A ES 556468A ES 556468 A ES556468 A ES 556468A ES 8801291 A1 ES8801291 A1 ES 8801291A1
- Authority
- ES
- Spain
- Prior art keywords
- cephalosporins
- processes
- preparation
- pharmaceutical compositions
- compositions containing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 238000000034 method Methods 0.000 title abstract 2
- 229930186147 Cephalosporin Natural products 0.000 title 1
- 229940124587 cephalosporin Drugs 0.000 title 1
- 150000001780 cephalosporins Chemical class 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
- 241000124008 Mammalia Species 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 239000000839 emulsion Substances 0.000 abstract 1
- 208000015181 infectious disease Diseases 0.000 abstract 1
- 230000001681 protective effect Effects 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
- C07D501/57—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with a further substituent in position 7, e.g. cephamycines
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Cephalosporin Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Sub-Exchange Stations And Push- Button Telephones (AREA)
Abstract
PROCEDIMIENTO PARA PREPARAR NUEVOS DERIVADOS DE B-LACTAMA. CONSISTE EN HACER REACCIONAR A UN COMPUESTO DE FORMULA (II) CON UN DERIVADO N-ACILANTE DE UN ACIDO DE FORMULA (III), ENTRE C50 Y B50JC Y EN UNA EMULSION ACUOSA PARA OBTENER UN COMPUESTO DE FORMULA (I) Y SUS SALES FARMACEUTICAMENTE ACEPTABLES. SIENDO: R, ALQUILO DE C 1 A 8; R1, FENILO, 3-AMINOFENILO Y B-AMINOFENILO Y R8, H O UN GRUPO PROTECTOR DEL CARBOXI. SE UTILIZAN EN EL TRATAMIENTO DE INFECCIONES EN MAMIFEROS CAUSADAS POR ORGANISMOS GRAM -(-).
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB858516020A GB8516020D0 (en) | 1985-06-25 | 1985-06-25 | Compounds |
| GB858531681A GB8531681D0 (en) | 1985-12-23 | 1985-12-23 | Compounds |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES556468A0 ES556468A0 (es) | 1987-12-16 |
| ES8801291A1 true ES8801291A1 (es) | 1987-12-16 |
Family
ID=26289417
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES556468A Expired ES8801291A1 (es) | 1985-06-25 | 1986-06-23 | Un procedimiento para la preparacion de nuevos derivados de beta-lactama. |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US4835150A (es) |
| EP (1) | EP0219926A3 (es) |
| AU (1) | AU5895086A (es) |
| DK (1) | DK295486A (es) |
| ES (1) | ES8801291A1 (es) |
| FI (1) | FI862679L (es) |
| GR (1) | GR861634B (es) |
| HU (1) | HUT43076A (es) |
| JO (1) | JO1444B1 (es) |
| NO (1) | NO862518L (es) |
| NZ (1) | NZ216624A (es) |
| PT (1) | PT82838B (es) |
| YU (1) | YU108586A (es) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8722477D0 (en) * | 1987-09-24 | 1987-10-28 | Beecham Group Plc | Compounds |
| EP0416810B1 (en) * | 1989-09-04 | 1995-02-08 | Beecham Group p.l.c. | Cephalosporin compounds, process for their preparation, pharmaceutical compositions and intermediates |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2107307B (en) * | 1981-07-25 | 1986-02-26 | Beecham Group Plc | B-lactum antibacterial agents |
| US4670431A (en) * | 1983-01-21 | 1987-06-02 | Beecham Group P.L.C. | Beta-lactam antibacterial agents |
| NZ206893A (en) * | 1983-01-24 | 1987-02-20 | Beecham Group Plc | Cephalosporin derivatives and pharmaceutical compositions;and 7-amino intermediates |
-
1986
- 1986-06-19 EP EP86304733A patent/EP0219926A3/en not_active Withdrawn
- 1986-06-21 JO JO19861444A patent/JO1444B1/en active
- 1986-06-23 YU YU01085/86A patent/YU108586A/xx unknown
- 1986-06-23 AU AU58950/86A patent/AU5895086A/en not_active Abandoned
- 1986-06-23 DK DK295486A patent/DK295486A/da not_active Application Discontinuation
- 1986-06-23 NO NO862518A patent/NO862518L/no unknown
- 1986-06-23 NZ NZ216624A patent/NZ216624A/xx unknown
- 1986-06-23 US US06/877,295 patent/US4835150A/en not_active Expired - Fee Related
- 1986-06-23 HU HU862627A patent/HUT43076A/hu unknown
- 1986-06-23 ES ES556468A patent/ES8801291A1/es not_active Expired
- 1986-06-24 FI FI862679A patent/FI862679L/fi not_active IP Right Cessation
- 1986-06-24 PT PT82838A patent/PT82838B/pt unknown
- 1986-06-24 GR GR861634A patent/GR861634B/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU5895086A (en) | 1987-01-08 |
| FI862679A7 (fi) | 1986-12-26 |
| PT82838A (en) | 1986-07-01 |
| HUT43076A (en) | 1987-09-28 |
| EP0219926A2 (en) | 1987-04-29 |
| YU108586A (en) | 1987-12-31 |
| PT82838B (en) | 1987-10-12 |
| ES556468A0 (es) | 1987-12-16 |
| DK295486A (da) | 1986-12-26 |
| DK295486D0 (da) | 1986-06-23 |
| GR861634B (en) | 1986-10-30 |
| NZ216624A (en) | 1988-08-30 |
| JO1444B1 (en) | 1988-03-10 |
| FI862679L (fi) | 1986-12-26 |
| US4835150A (en) | 1989-05-30 |
| NO862518L (no) | 1986-12-29 |
| FI862679A0 (fi) | 1986-06-24 |
| EP0219926A3 (en) | 1988-08-31 |
| NO862518D0 (no) | 1986-06-23 |
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