DE3306503A1 - Heterocyclische verbindungen, verfahren zu ihrer herstellung und diese verbindungen enthaltenden arzneimittel - Google Patents

Heterocyclische verbindungen, verfahren zu ihrer herstellung und diese verbindungen enthaltenden arzneimittel

Info

Publication number
DE3306503A1
DE3306503A1 DE19833306503 DE3306503A DE3306503A1 DE 3306503 A1 DE3306503 A1 DE 3306503A1 DE 19833306503 DE19833306503 DE 19833306503 DE 3306503 A DE3306503 A DE 3306503A DE 3306503 A1 DE3306503 A1 DE 3306503A1
Authority
DE
Germany
Prior art keywords
group
alkyl
stands
substituted
methyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
DE19833306503
Other languages
German (de)
English (en)
Inventor
David Edmund Ware Hertfordshire Bays
John Watson Sawbridgeworth Hertfordshire Clitherow
Roger Potters Bar Hertfordshire Hayes
Barry John Tewin Wood Hertfordshire Price
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glaxo Group Ltd
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of DE3306503A1 publication Critical patent/DE3306503A1/de
Withdrawn legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44Iso-indoles; Hydrogenated iso-indoles
    • C07D209/48Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D249/00Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/081,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C07D249/101,2,4-Triazoles; Hydrogenated 1,2,4-triazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D249/14Nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/096Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
DE19833306503 1982-02-24 1983-02-24 Heterocyclische verbindungen, verfahren zu ihrer herstellung und diese verbindungen enthaltenden arzneimittel Withdrawn DE3306503A1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8205431 1982-02-24
GB8205723 1982-02-26

Publications (1)

Publication Number Publication Date
DE3306503A1 true DE3306503A1 (de) 1983-09-01

Family

ID=26282061

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19833306503 Withdrawn DE3306503A1 (de) 1982-02-24 1983-02-24 Heterocyclische verbindungen, verfahren zu ihrer herstellung und diese verbindungen enthaltenden arzneimittel

Country Status (18)

Country Link
JP (1) JPS58157772A (fr)
AU (1) AU1180383A (fr)
BE (1) BE896012A (fr)
DE (1) DE3306503A1 (fr)
DK (1) DK88283A (fr)
ES (2) ES8407030A1 (fr)
FI (1) FI830609L (fr)
FR (1) FR2521993B1 (fr)
GB (1) GB2116178B (fr)
GR (1) GR77048B (fr)
IL (1) IL67990A0 (fr)
IT (1) IT1167622B (fr)
LU (1) LU84659A1 (fr)
NL (1) NL8300697A (fr)
NO (1) NO830643L (fr)
NZ (1) NZ203384A (fr)
PT (1) PT76280A (fr)
SE (1) SE8301039L (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3336410A1 (de) * 1983-10-06 1985-04-18 Ludwig Heumann & Co GmbH, 8500 Nürnberg Sulfenamidderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
FR2815346B1 (fr) * 2000-10-13 2004-02-20 Servier Lab Nouveaux composes aminotriazolones, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FI68395C (fi) * 1979-03-02 1985-09-10 Glaxo Group Ltd Foerfarande foer framstaellning av farmakologiskt verksamma trazolfoereningar
AU539189B2 (en) * 1979-10-22 1984-09-13 Glaxo Group Limited 1h-1,2,4-triazole derivatives
ES496164A0 (es) * 1979-10-22 1982-04-01 Glaxo Group Ltd Un procedimiento para la produccion de nuevos derivados heterociclicos,.
GB2064515B (en) * 1979-10-23 1983-06-29 Glaxo Group Ltd Heterocyclic derivatives processes for their production and pharmaceutical compositions containing them
FR2477150A1 (fr) * 1980-02-28 1981-09-04 Glaxo Group Ltd Nouveaux derives heterocycliques, procedes pour leur preparation et compositions pharmaceutiques les comportant

Also Published As

Publication number Publication date
FR2521993A1 (fr) 1983-08-26
GB2116178B (en) 1985-10-02
NO830643L (no) 1983-08-25
IT1167622B (it) 1987-05-13
GB2116178A (en) 1983-09-21
GR77048B (fr) 1984-09-04
NL8300697A (nl) 1983-09-16
SE8301039D0 (sv) 1983-02-24
NZ203384A (en) 1985-08-16
ES520031A0 (es) 1984-04-01
GB8305147D0 (en) 1983-03-30
ES8407030A1 (es) 1984-04-01
LU84659A1 (fr) 1984-11-08
ES8602702A1 (es) 1985-11-16
BE896012A (fr) 1983-08-24
FI830609L (fi) 1983-08-25
FI830609A0 (fi) 1983-02-24
IL67990A0 (en) 1983-06-15
SE8301039L (sv) 1983-08-25
DK88283D0 (da) 1983-02-24
FR2521993B1 (fr) 1988-09-16
IT8347786A0 (it) 1983-02-24
AU1180383A (en) 1983-09-01
ES526532A0 (es) 1985-11-16
JPS58157772A (ja) 1983-09-19
DK88283A (da) 1983-08-25
PT76280A (en) 1983-03-01

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Legal Events

Date Code Title Description
8139 Disposal/non-payment of the annual fee