ES8602702A1 - Un procedimiento para la preparacion de derivados del triazol - Google Patents
Un procedimiento para la preparacion de derivados del triazolInfo
- Publication number
- ES8602702A1 ES8602702A1 ES526532A ES526532A ES8602702A1 ES 8602702 A1 ES8602702 A1 ES 8602702A1 ES 526532 A ES526532 A ES 526532A ES 526532 A ES526532 A ES 526532A ES 8602702 A1 ES8602702 A1 ES 8602702A1
- Authority
- ES
- Spain
- Prior art keywords
- alkyl
- group
- substituted
- oxygen
- sulphur
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/44—Iso-indoles; Hydrogenated iso-indoles
- C07D209/48—Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
- C07D249/10—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D249/14—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/096—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
PROCEDIMIENTO PARA LA PREPARACION DE DERIVADOS DE TRIAZOL DE FORMULA GENERAL (I). CONSISTENTE EN HACER REACCIONAR UN TRIAZOL DE LA MISMA FORMULA GENERAL (I) CON UN ANION DE FORMULA (II) EN PRESENCIA O AUSENCIA DE DISOLVENTE, A UNA TEMPERATURA COMPRENDIDA ENTRE 20 Y 120C. OPCIONALMENTE PUEDE TRATARSE AL COMPUESTO OBTENIDO DE FORMULA (I) EN EL QUE R8 ES UN GRUPO HIDROXILO CON UN REACTIVO CAPAZ DE CONVERTIR EL GRUPO HIDROXILO EN UN GRUPO SALIENTE Y POSTERIORMENTE CON AMONIACO O UNA AMINA SECUNDARIA, EN AUSENCIA O PRESENCIA DE DISOLVENTES, A UNA TEMPERATURA COMPRENDIDA ENTRE 80 Y 120C Y EVENTUALMENTE CONVERTIR AL PRODUCTO EN UNA SAL R1 Y R2 REPRESENTAN ENTRE OTROS, HIDROGENO, ALQUILO, ALK UNA CADENA ALQUILENICA, Q UN ANILLO DE FURANO O TIOFENO. X E Y OXIGENO, AZUFRE, METILENO O UN ENLACE, N 1-3, M 2-5, A Y B NITROGENO O UN CARBONO SUSTITUIDO, RESPECTIVAMENTE, 7 OXIGENO O AZUFRE. DE APLICACION EN EL TRATAMIENTO DE ULCERAS GASTRICAS, ESTADOS ALERGICOS E INFLAMATORIOS.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB8205431 | 1982-02-24 | ||
GB8205723 | 1982-02-26 |
Publications (2)
Publication Number | Publication Date |
---|---|
ES526532A0 ES526532A0 (es) | 1985-11-16 |
ES8602702A1 true ES8602702A1 (es) | 1985-11-16 |
Family
ID=26282061
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES520031A Granted ES520031A0 (es) | 1982-02-24 | 1983-02-23 | Un procedimiento para prepararacion de derivados del triazol. |
ES526532A Expired ES8602702A1 (es) | 1982-02-24 | 1983-10-17 | Un procedimiento para la preparacion de derivados del triazol |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES520031A Granted ES520031A0 (es) | 1982-02-24 | 1983-02-23 | Un procedimiento para prepararacion de derivados del triazol. |
Country Status (18)
Country | Link |
---|---|
JP (1) | JPS58157772A (es) |
AU (1) | AU1180383A (es) |
BE (1) | BE896012A (es) |
DE (1) | DE3306503A1 (es) |
DK (1) | DK88283A (es) |
ES (2) | ES520031A0 (es) |
FI (1) | FI830609L (es) |
FR (1) | FR2521993B1 (es) |
GB (1) | GB2116178B (es) |
GR (1) | GR77048B (es) |
IL (1) | IL67990A0 (es) |
IT (1) | IT1167622B (es) |
LU (1) | LU84659A1 (es) |
NL (1) | NL8300697A (es) |
NO (1) | NO830643L (es) |
NZ (1) | NZ203384A (es) |
PT (1) | PT76280A (es) |
SE (1) | SE8301039L (es) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3336410A1 (de) * | 1983-10-06 | 1985-04-18 | Ludwig Heumann & Co GmbH, 8500 Nürnberg | Sulfenamidderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
FR2815346B1 (fr) * | 2000-10-13 | 2004-02-20 | Servier Lab | Nouveaux composes aminotriazolones, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL59503A (en) * | 1979-03-02 | 1985-03-31 | Glaxo Group Ltd | 1,2,4-triazol derivatives,their preparation and pharmaceutical compositions containing them |
DK446980A (da) * | 1979-10-22 | 1981-04-23 | Glaxo Group Ltd | R fremgangsmaade til fremstilling af heterocycliske forbindelse |
EP0029303B1 (en) * | 1979-10-22 | 1985-01-30 | Glaxo Group Limited | 1,2,4-triazole derivatives, processes for their production and pharmaceutical compositions containing them |
EP0029306B1 (en) * | 1979-10-23 | 1984-07-25 | Glaxo Group Limited | Aminoalkyl compounds, their production and pharmaceutical compositions containing them |
FR2477150A1 (fr) * | 1980-02-28 | 1981-09-04 | Glaxo Group Ltd | Nouveaux derives heterocycliques, procedes pour leur preparation et compositions pharmaceutiques les comportant |
-
1983
- 1983-02-23 ES ES520031A patent/ES520031A0/es active Granted
- 1983-02-23 PT PT76280A patent/PT76280A/pt unknown
- 1983-02-24 AU AU11803/83A patent/AU1180383A/en not_active Abandoned
- 1983-02-24 FI FI830609A patent/FI830609L/fi not_active Application Discontinuation
- 1983-02-24 JP JP58030160A patent/JPS58157772A/ja active Pending
- 1983-02-24 BE BE0/210201A patent/BE896012A/fr not_active IP Right Cessation
- 1983-02-24 SE SE8301039A patent/SE8301039L/xx not_active Application Discontinuation
- 1983-02-24 FR FR8303011A patent/FR2521993B1/fr not_active Expired
- 1983-02-24 DK DK88283A patent/DK88283A/da not_active Application Discontinuation
- 1983-02-24 LU LU84659A patent/LU84659A1/fr unknown
- 1983-02-24 IT IT47786/83A patent/IT1167622B/it active
- 1983-02-24 NL NL8300697A patent/NL8300697A/nl not_active Application Discontinuation
- 1983-02-24 GB GB08305147A patent/GB2116178B/en not_active Expired
- 1983-02-24 IL IL67990A patent/IL67990A0/xx unknown
- 1983-02-24 NO NO830643A patent/NO830643L/no unknown
- 1983-02-24 NZ NZ203384A patent/NZ203384A/en unknown
- 1983-02-24 DE DE19833306503 patent/DE3306503A1/de not_active Withdrawn
- 1983-02-24 GR GR70604A patent/GR77048B/el unknown
- 1983-10-17 ES ES526532A patent/ES8602702A1/es not_active Expired
Also Published As
Publication number | Publication date |
---|---|
SE8301039L (sv) | 1983-08-25 |
FR2521993A1 (fr) | 1983-08-26 |
GB2116178B (en) | 1985-10-02 |
GB8305147D0 (en) | 1983-03-30 |
LU84659A1 (fr) | 1984-11-08 |
DE3306503A1 (de) | 1983-09-01 |
DK88283D0 (da) | 1983-02-24 |
NZ203384A (en) | 1985-08-16 |
JPS58157772A (ja) | 1983-09-19 |
IT1167622B (it) | 1987-05-13 |
NL8300697A (nl) | 1983-09-16 |
ES526532A0 (es) | 1985-11-16 |
DK88283A (da) | 1983-08-25 |
AU1180383A (en) | 1983-09-01 |
ES8407030A1 (es) | 1984-04-01 |
GR77048B (es) | 1984-09-04 |
FI830609L (fi) | 1983-08-25 |
NO830643L (no) | 1983-08-25 |
IT8347786A0 (it) | 1983-02-24 |
IL67990A0 (en) | 1983-06-15 |
GB2116178A (en) | 1983-09-21 |
PT76280A (en) | 1983-03-01 |
FI830609A0 (fi) | 1983-02-24 |
ES520031A0 (es) | 1984-04-01 |
FR2521993B1 (fr) | 1988-09-16 |
SE8301039D0 (sv) | 1983-02-24 |
BE896012A (fr) | 1983-08-24 |
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