IT1167622B - Derivati eterociclici furan o tiofen-sostituiti, procedimento per prepararli e composizioni farmaceutiche che li comprendono - Google Patents

Derivati eterociclici furan o tiofen-sostituiti, procedimento per prepararli e composizioni farmaceutiche che li comprendono

Info

Publication number
IT1167622B
IT1167622B IT47786/83A IT4778683A IT1167622B IT 1167622 B IT1167622 B IT 1167622B IT 47786/83 A IT47786/83 A IT 47786/83A IT 4778683 A IT4778683 A IT 4778683A IT 1167622 B IT1167622 B IT 1167622B
Authority
IT
Italy
Prior art keywords
thiofen
furan
prepare
procedure
pharmaceutical compositions
Prior art date
Application number
IT47786/83A
Other languages
English (en)
Other versions
IT8347786A0 (it
Inventor
John Watson Clitherow
Barry John Price
Roger Hayes
David Edmund Bays
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of IT8347786A0 publication Critical patent/IT8347786A0/it
Application granted granted Critical
Publication of IT1167622B publication Critical patent/IT1167622B/it

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44Iso-indoles; Hydrogenated iso-indoles
    • C07D209/48Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D249/00Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/081,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C07D249/101,2,4-Triazoles; Hydrogenated 1,2,4-triazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D249/14Nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/096Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
IT47786/83A 1982-02-24 1983-02-24 Derivati eterociclici furan o tiofen-sostituiti, procedimento per prepararli e composizioni farmaceutiche che li comprendono IT1167622B (it)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8205431 1982-02-24
GB8205723 1982-02-26

Publications (2)

Publication Number Publication Date
IT8347786A0 IT8347786A0 (it) 1983-02-24
IT1167622B true IT1167622B (it) 1987-05-13

Family

ID=26282061

Family Applications (1)

Application Number Title Priority Date Filing Date
IT47786/83A IT1167622B (it) 1982-02-24 1983-02-24 Derivati eterociclici furan o tiofen-sostituiti, procedimento per prepararli e composizioni farmaceutiche che li comprendono

Country Status (18)

Country Link
JP (1) JPS58157772A (it)
AU (1) AU1180383A (it)
BE (1) BE896012A (it)
DE (1) DE3306503A1 (it)
DK (1) DK88283A (it)
ES (2) ES520031A0 (it)
FI (1) FI830609L (it)
FR (1) FR2521993B1 (it)
GB (1) GB2116178B (it)
GR (1) GR77048B (it)
IL (1) IL67990A0 (it)
IT (1) IT1167622B (it)
LU (1) LU84659A1 (it)
NL (1) NL8300697A (it)
NO (1) NO830643L (it)
NZ (1) NZ203384A (it)
PT (1) PT76280A (it)
SE (1) SE8301039L (it)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3336410A1 (de) * 1983-10-06 1985-04-18 Ludwig Heumann & Co GmbH, 8500 Nürnberg Sulfenamidderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
FR2815346B1 (fr) * 2000-10-13 2004-02-20 Servier Lab Nouveaux composes aminotriazolones, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL59503A (en) * 1979-03-02 1985-03-31 Glaxo Group Ltd 1,2,4-triazol derivatives,their preparation and pharmaceutical compositions containing them
DK446980A (da) * 1979-10-22 1981-04-23 Glaxo Group Ltd R fremgangsmaade til fremstilling af heterocycliske forbindelse
EP0029303B1 (en) * 1979-10-22 1985-01-30 Glaxo Group Limited 1,2,4-triazole derivatives, processes for their production and pharmaceutical compositions containing them
EP0029306B1 (en) * 1979-10-23 1984-07-25 Glaxo Group Limited Aminoalkyl compounds, their production and pharmaceutical compositions containing them
FR2477150A1 (fr) * 1980-02-28 1981-09-04 Glaxo Group Ltd Nouveaux derives heterocycliques, procedes pour leur preparation et compositions pharmaceutiques les comportant

Also Published As

Publication number Publication date
SE8301039L (sv) 1983-08-25
FR2521993A1 (fr) 1983-08-26
GB2116178B (en) 1985-10-02
GB8305147D0 (en) 1983-03-30
LU84659A1 (fr) 1984-11-08
DE3306503A1 (de) 1983-09-01
DK88283D0 (da) 1983-02-24
NZ203384A (en) 1985-08-16
JPS58157772A (ja) 1983-09-19
NL8300697A (nl) 1983-09-16
ES526532A0 (es) 1985-11-16
DK88283A (da) 1983-08-25
AU1180383A (en) 1983-09-01
ES8407030A1 (es) 1984-04-01
GR77048B (it) 1984-09-04
FI830609L (fi) 1983-08-25
NO830643L (no) 1983-08-25
IT8347786A0 (it) 1983-02-24
IL67990A0 (en) 1983-06-15
GB2116178A (en) 1983-09-21
PT76280A (en) 1983-03-01
FI830609A0 (fi) 1983-02-24
ES8602702A1 (es) 1985-11-16
ES520031A0 (es) 1984-04-01
FR2521993B1 (fr) 1988-09-16
SE8301039D0 (sv) 1983-02-24
BE896012A (fr) 1983-08-24

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