GB2116178B - Heterocyclic derivatives - Google Patents

Heterocyclic derivatives

Info

Publication number
GB2116178B
GB2116178B GB08305147A GB8305147A GB2116178B GB 2116178 B GB2116178 B GB 2116178B GB 08305147 A GB08305147 A GB 08305147A GB 8305147 A GB8305147 A GB 8305147A GB 2116178 B GB2116178 B GB 2116178B
Authority
GB
United Kingdom
Prior art keywords
heterocyclic derivatives
heterocyclic
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB08305147A
Other languages
English (en)
Other versions
GB2116178A (en
GB8305147D0 (en
Inventor
John Watson Clitherow
Barry John Price
Roger Hayes
David Edmund Bays
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glaxo Group Ltd
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of GB8305147D0 publication Critical patent/GB8305147D0/en
Publication of GB2116178A publication Critical patent/GB2116178A/en
Application granted granted Critical
Publication of GB2116178B publication Critical patent/GB2116178B/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44—Iso-indoles; Hydrogenated iso-indoles
    • C07D209/48—Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C07D249/10—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D249/14—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/096—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
GB08305147A 1982-02-24 1983-02-24 Heterocyclic derivatives Expired GB2116178B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8205431 1982-02-24
GB8205723 1982-02-26

Publications (3)

Publication Number Publication Date
GB8305147D0 GB8305147D0 (en) 1983-03-30
GB2116178A GB2116178A (en) 1983-09-21
GB2116178B true GB2116178B (en) 1985-10-02

Family

ID=26282061

Family Applications (1)

Application Number Title Priority Date Filing Date
GB08305147A Expired GB2116178B (en) 1982-02-24 1983-02-24 Heterocyclic derivatives

Country Status (18)

Country Link
JP (1) JPS58157772A (fr)
AU (1) AU1180383A (fr)
BE (1) BE896012A (fr)
DE (1) DE3306503A1 (fr)
DK (1) DK88283A (fr)
ES (2) ES8407030A1 (fr)
FI (1) FI830609L (fr)
FR (1) FR2521993B1 (fr)
GB (1) GB2116178B (fr)
GR (1) GR77048B (fr)
IL (1) IL67990A0 (fr)
IT (1) IT1167622B (fr)
LU (1) LU84659A1 (fr)
NL (1) NL8300697A (fr)
NO (1) NO830643L (fr)
NZ (1) NZ203384A (fr)
PT (1) PT76280A (fr)
SE (1) SE8301039L (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3336410A1 (de) * 1983-10-06 1985-04-18 Ludwig Heumann & Co GmbH, 8500 Nürnberg Sulfenamidderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
FR2815346B1 (fr) * 2000-10-13 2004-02-20 Servier Lab Nouveaux composes aminotriazolones, leur procede de preparation et les compositions pharmaceutiques qui les contiennent

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
YU56680A (en) * 1979-03-02 1983-04-30 Glaxo Group Ltd Process for obtaining new 1,2,4-triazole derivatives
US4410523A (en) * 1979-10-22 1983-10-18 Glaxo Group Limited Heterocyclic derivatives
EP0029303B1 (fr) * 1979-10-22 1985-01-30 Glaxo Group Limited Dérivés du 1,2,4-triazole, procédés pour leur préparation et compositions pharmaceutiques les contenant
EP0029306B1 (fr) * 1979-10-23 1984-07-25 Glaxo Group Limited Composés aminoalkyliques, leur préparation et compositions pharmaceutiques les contenant
CH655104A5 (fr) * 1980-02-28 1986-03-27 Glaxo Group Ltd Derives heterocycliques triazoliques, procedes pour leur preparation et compositions pharmaceutiques les comportant.

Also Published As

Publication number Publication date
SE8301039L (sv) 1983-08-25
FI830609A0 (fi) 1983-02-24
IL67990A0 (en) 1983-06-15
ES520031A0 (es) 1984-04-01
BE896012A (fr) 1983-08-24
ES8602702A1 (es) 1985-11-16
NO830643L (no) 1983-08-25
GB2116178A (en) 1983-09-21
LU84659A1 (fr) 1984-11-08
DK88283D0 (da) 1983-02-24
FI830609L (fi) 1983-08-25
NZ203384A (en) 1985-08-16
GR77048B (fr) 1984-09-04
FR2521993A1 (fr) 1983-08-26
ES8407030A1 (es) 1984-04-01
DE3306503A1 (de) 1983-09-01
NL8300697A (nl) 1983-09-16
GB8305147D0 (en) 1983-03-30
JPS58157772A (ja) 1983-09-19
PT76280A (en) 1983-03-01
IT8347786A0 (it) 1983-02-24
SE8301039D0 (sv) 1983-02-24
DK88283A (da) 1983-08-25
AU1180383A (en) 1983-09-01
IT1167622B (it) 1987-05-13
ES526532A0 (es) 1985-11-16
FR2521993B1 (fr) 1988-09-16

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Legal Events

Date Code Title Description
PCNP Patent ceased through non-payment of renewal fee