DE3008257C2 - Verfahren zur Herstellung von Penicillansäure-1,1-dioxid und dessen Estern - Google Patents

Verfahren zur Herstellung von Penicillansäure-1,1-dioxid und dessen Estern

Info

Publication number
DE3008257C2
DE3008257C2 DE3008257A DE3008257A DE3008257C2 DE 3008257 C2 DE3008257 C2 DE 3008257C2 DE 3008257 A DE3008257 A DE 3008257A DE 3008257 A DE3008257 A DE 3008257A DE 3008257 C2 DE3008257 C2 DE 3008257C2
Authority
DE
Germany
Prior art keywords
dioxide
acid
solution
added
ethyl acetate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE3008257A
Other languages
German (de)
English (en)
Other versions
DE3008257A1 (de
Inventor
Ronnie D. East Lyme Conn. Carroll
Bernard Shields Waterford Conn. Moore
Robert Alfred Ledyard Conn. Volkmann
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Inc
Original Assignee
Pfizer Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Inc filed Critical Pfizer Inc
Publication of DE3008257A1 publication Critical patent/DE3008257A1/de
Application granted granted Critical
Publication of DE3008257C2 publication Critical patent/DE3008257C2/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D499/00—Heterocyclic compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. penicillins, penems; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DE3008257A 1979-03-05 1980-03-04 Verfahren zur Herstellung von Penicillansäure-1,1-dioxid und dessen Estern Expired DE3008257C2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US1780879A 1979-03-05 1979-03-05
US1781079A 1979-03-05 1979-03-05

Publications (2)

Publication Number Publication Date
DE3008257A1 DE3008257A1 (de) 1980-09-11
DE3008257C2 true DE3008257C2 (de) 1984-03-01

Family

ID=26690337

Family Applications (1)

Application Number Title Priority Date Filing Date
DE3008257A Expired DE3008257C2 (de) 1979-03-05 1980-03-04 Verfahren zur Herstellung von Penicillansäure-1,1-dioxid und dessen Estern

Country Status (36)

Country Link
KR (1) KR850001339B1 (fi)
AR (1) AR225031A1 (fi)
AT (1) AT366693B (fi)
AU (1) AU522572B2 (fi)
BG (1) BG33292A3 (fi)
CH (1) CH644608A5 (fi)
CS (1) CS215130B2 (fi)
DD (1) DD149367A5 (fi)
DE (1) DE3008257C2 (fi)
DK (2) DK159852C (fi)
EG (1) EG14437A (fi)
ES (1) ES8103094A1 (fi)
FI (1) FI70024C (fi)
FR (1) FR2450836B1 (fi)
GB (1) GB2045755B (fi)
GR (1) GR67234B (fi)
HK (1) HK66587A (fi)
HU (1) HU186304B (fi)
IE (1) IE49535B1 (fi)
IL (1) IL59515A (fi)
IN (1) IN153685B (fi)
IT (1) IT1130300B (fi)
KE (1) KE3464A (fi)
LU (1) LU82215A1 (fi)
MX (1) MX6032E (fi)
MY (1) MY8500319A (fi)
NL (1) NL180317C (fi)
NO (2) NO800618L (fi)
PL (1) PL125197B1 (fi)
PT (1) PT70897A (fi)
RO (1) RO80112A (fi)
SE (2) SE449103B (fi)
SG (1) SG55884G (fi)
SU (1) SU1192626A3 (fi)
UA (1) UA6342A1 (fi)
YU (1) YU42328B (fi)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IN159362B (fi) * 1981-03-23 1987-05-09 Pfizer
US4419284A (en) * 1981-03-23 1983-12-06 Pfizer Inc. Preparation of halomethyl esters (and related esters) of penicillanic acid 1,1-dioxide
PT76527B (en) * 1982-04-19 1985-12-09 Gist Brocades Nv A process for the preparation of penicillanic acid 1,1-dioxide and derivatives thereof
IT1190897B (it) * 1982-06-29 1988-02-24 Opos Biochimica Srl Procedimento per la preparazione dell'estere 1-etossicarbonilossietilico dell'acido 6-(d(-)-alfa aminoalfa fenilacetamido)-penicillanico
US4606865A (en) * 1982-09-20 1986-08-19 Astra Lakemedel Aktiebolag Methods for the preparation of α-bromodiethylcarbonate
EP0139047A1 (en) * 1983-10-18 1985-05-02 Gist-Brocades N.V. Process for the preparation of 6,6-dibromopenicillanic acid 1,1-dioxide
EP0139048A1 (en) * 1983-10-18 1985-05-02 Gist-Brocades N.V. Process for the dehalogenation of 6,6-dibromopenicillanic acid 1,1-dioxide
US4596677A (en) * 1984-04-06 1986-06-24 Bristol-Myers Company Anhydropenicillin intermediates

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IN149747B (fi) * 1977-06-07 1982-04-03 Pfizer
CA1158639A (en) * 1978-12-11 1983-12-13 Eric M. Gordon 6-bromopenicillanic acid sulfone
EP0013617B1 (en) * 1979-01-10 1984-07-04 Beecham Group Plc Penicillin derivatives, process for their preparation and pharmaceutical compositions containing certain of these compounds
IE49880B1 (en) * 1979-02-13 1986-01-08 Leo Pharm Prod Ltd Penicillin derivatives

Also Published As

Publication number Publication date
ES489185A0 (es) 1981-02-16
GB2045755A (en) 1980-11-05
DK159852B (da) 1990-12-17
NO800618L (no) 1980-09-08
AR225031A1 (es) 1982-02-15
DK166353B (da) 1993-04-13
HK66587A (en) 1987-09-25
AU522572B2 (en) 1982-06-17
GR67234B (fi) 1981-06-25
ATA119080A (de) 1981-09-15
DE3008257A1 (de) 1980-09-11
IT1130300B (it) 1986-06-11
BG33292A3 (en) 1983-01-14
CS215130B2 (en) 1982-07-30
IL59515A (en) 1983-02-23
RO80112A (ro) 1982-10-26
DK166353C (da) 1993-09-06
FR2450836A1 (fr) 1980-10-03
FI800661A (fi) 1980-09-06
PL222448A1 (fi) 1981-01-02
NO823127L (no) 1980-09-08
NL8001285A (nl) 1980-09-09
FI70024C (fi) 1986-09-12
KR850001339B1 (ko) 1985-09-19
SU1192626A3 (ru) 1985-11-15
IT8020367A0 (it) 1980-03-05
PT70897A (en) 1980-04-01
KE3464A (en) 1984-10-12
DK92680A (da) 1980-09-06
DK159852C (da) 1991-05-06
IN153685B (fi) 1984-08-04
AT366693B (de) 1982-04-26
GB2045755B (en) 1983-01-26
DD149367A5 (de) 1981-07-08
NL180317B (nl) 1986-09-01
SE8603309D0 (sv) 1986-08-04
SE449103B (sv) 1987-04-06
SG55884G (en) 1985-03-08
ES8103094A1 (es) 1981-02-16
SE8603309L (sv) 1986-08-04
SE8000512L (sv) 1980-09-06
YU58580A (en) 1983-02-28
HU186304B (en) 1985-07-29
YU42328B (en) 1988-08-31
MX6032E (es) 1984-10-04
PL125197B1 (en) 1983-04-30
UA6342A1 (uk) 1994-12-29
DK145690A (da) 1990-06-14
LU82215A1 (fr) 1980-09-24
FR2450836B1 (fr) 1986-03-21
FI70024B (fi) 1986-01-31
NL180317C (nl) 1987-02-02
MY8500319A (en) 1985-12-31
IL59515A0 (en) 1980-06-30
IE49535B1 (en) 1985-10-16
AU5610480A (en) 1980-09-11
EG14437A (en) 1984-09-30
CH644608A5 (de) 1984-08-15
DK145690D0 (da) 1990-06-14
IE800429L (en) 1980-09-05

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Legal Events

Date Code Title Description
OAP Request for examination filed
OD Request for examination
D2 Grant after examination
8364 No opposition during term of opposition