DE2950026C2 - Verfahren zur Herstellung von 11-Ketosteroiden - Google Patents

Verfahren zur Herstellung von 11-Ketosteroiden

Info

Publication number
DE2950026C2
DE2950026C2 DE2950026A DE2950026A DE2950026C2 DE 2950026 C2 DE2950026 C2 DE 2950026C2 DE 2950026 A DE2950026 A DE 2950026A DE 2950026 A DE2950026 A DE 2950026A DE 2950026 C2 DE2950026 C2 DE 2950026C2
Authority
DE
Germany
Prior art keywords
preparation
hydroxy
methyl
steroids
dione
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE2950026A
Other languages
German (de)
English (en)
Other versions
DE2950026B1 (de
Inventor
Ulrich Dr. 1000 Berlin Kerb
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Pharma AG
Original Assignee
Schering AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering AG filed Critical Schering AG
Priority to DE2950026A priority Critical patent/DE2950026C2/de
Priority to IL61601A priority patent/IL61601A/xx
Priority to DK515580A priority patent/DK146097C/da
Priority to EP80107595A priority patent/EP0030368B1/de
Priority to DE8080107595T priority patent/DE3062082D1/de
Priority to AT80107595T priority patent/ATE2534T1/de
Priority to IE2571/80A priority patent/IE50611B1/en
Priority to CA000366411A priority patent/CA1141750A/en
Priority to HU802948A priority patent/HU182250B/hu
Priority to US06/215,761 priority patent/US4315866A/en
Priority to JP17331680A priority patent/JPS5692900A/ja
Publication of DE2950026B1 publication Critical patent/DE2950026B1/de
Application granted granted Critical
Publication of DE2950026C2 publication Critical patent/DE2950026C2/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J63/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by expansion of only one ring by one or two atoms
    • C07J63/008—Expansion of ring D by one atom, e.g. D homo steroids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0003—Androstane derivatives
    • C07J1/0011—Androstane derivatives substituted in position 17 by a keto group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J13/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17
    • C07J13/005—Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17 with double bond in position 16 (17)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0007—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond not substituted in position 17 alfa
    • C07J5/0023—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond not substituted in position 17 alfa substituted in position 16
    • C07J5/003—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond not substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group including 16-alkylidene substitutes
    • C07J5/0038—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond not substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group including 16-alkylidene substitutes by an alkyl group

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
DE2950026A 1979-12-10 1979-12-10 Verfahren zur Herstellung von 11-Ketosteroiden Expired DE2950026C2 (de)

Priority Applications (11)

Application Number Priority Date Filing Date Title
DE2950026A DE2950026C2 (de) 1979-12-10 1979-12-10 Verfahren zur Herstellung von 11-Ketosteroiden
IL61601A IL61601A (en) 1979-12-10 1980-12-01 Process for preparing 11-keto steroids
DK515580A DK146097C (da) 1979-12-10 1980-12-03 Fremgangsmaade til fremstilling af 11-ketosteroider eller 11-keto-d-homosteroider
DE8080107595T DE3062082D1 (en) 1979-12-10 1980-12-04 Process for the preparation of 11-keto steroids
AT80107595T ATE2534T1 (de) 1979-12-10 1980-12-04 Verfahren zur herstellung von 11-ketosteroiden.
EP80107595A EP0030368B1 (de) 1979-12-10 1980-12-04 Verfahren zur Herstellung von 11-Ketosteroiden
IE2571/80A IE50611B1 (en) 1979-12-10 1980-12-09 Process for preparing 11-keto steroids
CA000366411A CA1141750A (en) 1979-12-10 1980-12-09 Process for the preparation of 11-keto steroids
HU802948A HU182250B (en) 1979-12-10 1980-12-09 Process for preparing 11-oxo-steroids
US06/215,761 US4315866A (en) 1979-12-10 1980-12-10 Process for preparing 11-keto steroids
JP17331680A JPS5692900A (en) 1979-12-10 1980-12-10 Manufacture of 111ketosteroid

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2950026A DE2950026C2 (de) 1979-12-10 1979-12-10 Verfahren zur Herstellung von 11-Ketosteroiden

Publications (2)

Publication Number Publication Date
DE2950026B1 DE2950026B1 (de) 1981-07-23
DE2950026C2 true DE2950026C2 (de) 1982-05-19

Family

ID=6088284

Family Applications (2)

Application Number Title Priority Date Filing Date
DE2950026A Expired DE2950026C2 (de) 1979-12-10 1979-12-10 Verfahren zur Herstellung von 11-Ketosteroiden
DE8080107595T Expired DE3062082D1 (en) 1979-12-10 1980-12-04 Process for the preparation of 11-keto steroids

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE8080107595T Expired DE3062082D1 (en) 1979-12-10 1980-12-04 Process for the preparation of 11-keto steroids

Country Status (10)

Country Link
US (1) US4315866A (enExample)
EP (1) EP0030368B1 (enExample)
JP (1) JPS5692900A (enExample)
AT (1) ATE2534T1 (enExample)
CA (1) CA1141750A (enExample)
DE (2) DE2950026C2 (enExample)
DK (1) DK146097C (enExample)
HU (1) HU182250B (enExample)
IE (1) IE50611B1 (enExample)
IL (1) IL61601A (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USRE35517E (en) * 1987-08-25 1997-05-20 University Of Southern California Method, compositions, and compounds for modulating brain excitability
US5120723A (en) * 1987-08-25 1992-06-09 University Of Southern California Method, compositions, and compounds for modulating brain excitability
US5232917A (en) * 1987-08-25 1993-08-03 University Of Southern California Methods, compositions, and compounds for allosteric modulation of the GABA receptor by members of the androstane and pregnane series
FR2691968B1 (fr) * 1992-06-04 1994-07-29 Roussel Uclaf Nouveau procede de preparation d'un derive sterouide 11-ceto.

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL7802905A (nl) * 1977-04-21 1978-10-24 Hoffmann La Roche Werkwijze voor het bereiden van d-homosteroiden.
DE2929558C2 (de) * 1979-07-18 1982-03-11 Schering Ag, 1000 Berlin Und 4619 Bergkamen Verfahren zur Herstellung von Δ↑9↑↑(↑↑1↑↑1↑↑)↑ und/oder Δ↑1↑↑6↑ ungesättigten Steroiden

Also Published As

Publication number Publication date
JPS5692900A (en) 1981-07-27
IE50611B1 (en) 1986-05-28
CA1141750A (en) 1983-02-22
IL61601A0 (en) 1981-01-30
HU182250B (en) 1983-12-28
EP0030368A1 (de) 1981-06-17
US4315866A (en) 1982-02-16
DE3062082D1 (en) 1983-03-24
ATE2534T1 (de) 1983-03-15
DK146097C (da) 1983-12-05
DE2950026B1 (de) 1981-07-23
JPS6352640B2 (enExample) 1988-10-19
IL61601A (en) 1984-09-30
DK515580A (da) 1981-06-11
EP0030368B1 (de) 1983-02-16
DK146097B (da) 1983-06-27
IE802571L (en) 1981-06-10

Similar Documents

Publication Publication Date Title
DE2950026C2 (de) Verfahren zur Herstellung von 11-Ketosteroiden
EP0023006B1 (de) Verfahren zur Herstellung von ungesättigten Steroiden
EP0042606B1 (de) Verfahren zur Herstellung von 17 Alpha-Hydroxy- und 17a Alpha-Hydroxy-D-homo-etiocarbonsäuren
DE1518994A1 (de) Verfahren zur Herstellung von neuen Beta,10Alpha-Steroiden
DE1793633C3 (de) Verfahren zur Herstellung von Gona 4(5),9(10)dien3 onen Ausscheidung aus 1468642
US2888468A (en) Process for the production of delta5-3-keto and delta4-3-keto steroids
DE1125422B (de) Verfahren zur Herstellung von 6-Fluor-í¸-3-ketosteoriden
DE1593686C (de) Verfahren zur Herstellung von 3 Ketobenzo eckige Klammer auf d,e eckige Klammer zus steroiden
AT220764B (de) Verfahren zur Herstellung von neuen 3-Oxo-Δ<1,4>-6-methyl- und 3-Oxo-Δ<1,4,6>-6-methylsteroiden
AT233175B (de) Verfahren zur Herstellung von 3-Oxo-Δ<1,4>- und 3-Oxo-Δ<1,4,6>-steroiden
AT265537B (de) Verfahren zur Herstellung von neuen 9β,10α-Steroiden
DE1166775B (de) Verfahren zur Herstellung von 19-nor-í¸-3-Ketosteroiden
DE1144270B (de) Verfahren zur Herstellung neuer anabolisch und progestativ wirkender ?-3-Keto-6-methyl-19-norsteroide
DE1803276A1 (de) Reagens zur Einfuehrung von Methylengruppen
DE1097440B (de) Verfahren zur Herstellung von í¸- oder í¸-3-Ketosteroiden der Pregnan- und Androstanreihe
DE1207383B (de) Verfahren zur Herstellung von 19-Nor-steroiden
CH497414A (de) Verfahren zur Herstellung von 16b, 17-Enoläthern von 17a-Hydroxy-16a-(oxoalkyl)-steroiden
DE1001680B (de) Verfahren zur Reduktion von in 4 (5)-Stellung ungesaettigten 6-Oxy-bzw. 6-Acyloxysterid-3-ketonen
DE2141127A1 (de) Neues verfahren zur herstellung wertvoller steroidderivate und zwischenprodukte fuer dieselben
DE1029375B (de) Verfahren zur Dehydratisierung von 11-Oxysteroiden der Androstan- und Pregnanreihe
DE1126866B (de) Verfahren zur Herstellung von 21-Fluorsteroiden der Pregnanreihe
DE1543012A1 (de) Verfahren zur Herstellung von neuen 9beta,10alpha-Steroiden
DE1164402B (de) Verfahren zur Einfuehrung einer Sauerstofffunktion in Steroide
DE1246725B (de) Verfahren zur Herstellung von 2-Alkyl-1, 11alpha-oxido-3-keto-delta 1,4, -androstadie
DE1060394B (de) Verfahren zur Herstellung von entzuendungswidrig wirkenden Steroiden

Legal Events

Date Code Title Description
8339 Ceased/non-payment of the annual fee