JPS5692900A - Manufacture of 111ketosteroid - Google Patents

Manufacture of 111ketosteroid

Info

Publication number
JPS5692900A
JPS5692900A JP17331680A JP17331680A JPS5692900A JP S5692900 A JPS5692900 A JP S5692900A JP 17331680 A JP17331680 A JP 17331680A JP 17331680 A JP17331680 A JP 17331680A JP S5692900 A JPS5692900 A JP S5692900A
Authority
JP
Japan
Prior art keywords
manufacture
steroid
aprotic
halo
beta
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP17331680A
Other languages
English (en)
Japanese (ja)
Other versions
JPS6352640B2 (enExample
Inventor
Shiyurutsue Pauruueebaaharuto
Kerupu Ururitsuhi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Pharma AG
Original Assignee
Schering AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering AG filed Critical Schering AG
Publication of JPS5692900A publication Critical patent/JPS5692900A/ja
Publication of JPS6352640B2 publication Critical patent/JPS6352640B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J63/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by expansion of only one ring by one or two atoms
    • C07J63/008—Expansion of ring D by one atom, e.g. D homo steroids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0003—Androstane derivatives
    • C07J1/0011—Androstane derivatives substituted in position 17 by a keto group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J13/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17
    • C07J13/005—Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17 with double bond in position 16 (17)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0007—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond not substituted in position 17 alfa
    • C07J5/0023—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond not substituted in position 17 alfa substituted in position 16
    • C07J5/003—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond not substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group including 16-alkylidene substitutes
    • C07J5/0038—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond not substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group including 16-alkylidene substitutes by an alkyl group

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
JP17331680A 1979-12-10 1980-12-10 Manufacture of 111ketosteroid Granted JPS5692900A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2950026A DE2950026C2 (de) 1979-12-10 1979-12-10 Verfahren zur Herstellung von 11-Ketosteroiden

Publications (2)

Publication Number Publication Date
JPS5692900A true JPS5692900A (en) 1981-07-27
JPS6352640B2 JPS6352640B2 (enExample) 1988-10-19

Family

ID=6088284

Family Applications (1)

Application Number Title Priority Date Filing Date
JP17331680A Granted JPS5692900A (en) 1979-12-10 1980-12-10 Manufacture of 111ketosteroid

Country Status (10)

Country Link
US (1) US4315866A (enExample)
EP (1) EP0030368B1 (enExample)
JP (1) JPS5692900A (enExample)
AT (1) ATE2534T1 (enExample)
CA (1) CA1141750A (enExample)
DE (2) DE2950026C2 (enExample)
DK (1) DK146097C (enExample)
HU (1) HU182250B (enExample)
IE (1) IE50611B1 (enExample)
IL (1) IL61601A (enExample)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USRE35517E (en) * 1987-08-25 1997-05-20 University Of Southern California Method, compositions, and compounds for modulating brain excitability
US5120723A (en) * 1987-08-25 1992-06-09 University Of Southern California Method, compositions, and compounds for modulating brain excitability
US5232917A (en) * 1987-08-25 1993-08-03 University Of Southern California Methods, compositions, and compounds for allosteric modulation of the GABA receptor by members of the androstane and pregnane series
FR2691968B1 (fr) * 1992-06-04 1994-07-29 Roussel Uclaf Nouveau procede de preparation d'un derive sterouide 11-ceto.

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL7802905A (nl) * 1977-04-21 1978-10-24 Hoffmann La Roche Werkwijze voor het bereiden van d-homosteroiden.
DE2929558C2 (de) * 1979-07-18 1982-03-11 Schering Ag, 1000 Berlin Und 4619 Bergkamen Verfahren zur Herstellung von Δ↑9↑↑(↑↑1↑↑1↑↑)↑ und/oder Δ↑1↑↑6↑ ungesättigten Steroiden

Also Published As

Publication number Publication date
IE50611B1 (en) 1986-05-28
CA1141750A (en) 1983-02-22
IL61601A0 (en) 1981-01-30
HU182250B (en) 1983-12-28
EP0030368A1 (de) 1981-06-17
US4315866A (en) 1982-02-16
DE3062082D1 (en) 1983-03-24
ATE2534T1 (de) 1983-03-15
DK146097C (da) 1983-12-05
DE2950026B1 (de) 1981-07-23
JPS6352640B2 (enExample) 1988-10-19
DE2950026C2 (de) 1982-05-19
IL61601A (en) 1984-09-30
DK515580A (da) 1981-06-11
EP0030368B1 (de) 1983-02-16
DK146097B (da) 1983-06-27
IE802571L (en) 1981-06-10

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