DE2858078C2 - 2-Chlorethylnitrosoharnstoffe, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende pharmazeutische Zubereitungen - Google Patents

2-Chlorethylnitrosoharnstoffe, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende pharmazeutische Zubereitungen

Info

Publication number
DE2858078C2
DE2858078C2 DE2858078A DE2858078A DE2858078C2 DE 2858078 C2 DE2858078 C2 DE 2858078C2 DE 2858078 A DE2858078 A DE 2858078A DE 2858078 A DE2858078 A DE 2858078A DE 2858078 C2 DE2858078 C2 DE 2858078C2
Authority
DE
Germany
Prior art keywords
chloroethyl
compounds
mice
nitroso
urea
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE2858078A
Other languages
German (de)
English (en)
Inventor
Yoshihisa Urawa Saitama Arai
Ozeki Wako Saitama Masakatsu
Kenji Urawa Saitama Tsujihara
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Tanabe Seiyaku Co Ltd
Original Assignee
Tanabe Seiyaku Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP9167477A external-priority patent/JPS5427526A/ja
Priority claimed from JP11425977A external-priority patent/JPS5448717A/ja
Priority claimed from JP1122578A external-priority patent/JPS54103826A/ja
Priority claimed from JP5856078A external-priority patent/JPS6026120B2/ja
Priority claimed from JP6345978A external-priority patent/JPS5919555B2/ja
Application filed by Tanabe Seiyaku Co Ltd filed Critical Tanabe Seiyaku Co Ltd
Priority to DE2858078A priority Critical patent/DE2858078C2/de
Application granted granted Critical
Publication of DE2858078C2 publication Critical patent/DE2858078C2/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/12—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by acids having the group -X-C(=X)-X-, or halides thereof, in which each X means nitrogen, oxygen, sulfur, selenium or tellurium, e.g. carbonic acid, carbamic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/66—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to halogen atoms or to nitro or nitroso groups
    • C07C275/68—N-nitroso ureas
DE2858078A 1977-07-29 1978-07-21 2-Chlorethylnitrosoharnstoffe, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende pharmazeutische Zubereitungen Expired DE2858078C2 (de)

Priority Applications (1)

Application Number Priority Date Filing Date Title
DE2858078A DE2858078C2 (de) 1977-07-29 1978-07-21 2-Chlorethylnitrosoharnstoffe, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende pharmazeutische Zubereitungen

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
JP9167477A JPS5427526A (en) 1977-07-29 1977-07-29 Nitrosourea compounds and their preparation
JP11425977A JPS5448717A (en) 1977-09-22 1977-09-22 Nitrosourea compounds and their preparation
JP1122578A JPS54103826A (en) 1978-02-02 1978-02-02 Nitrosourea derivative and its preparation
JP5856078A JPS6026120B2 (ja) 1978-05-16 1978-05-16 ニトロソ尿素誘導体の製法
JP6345978A JPS5919555B2 (ja) 1978-05-26 1978-05-26 ニトロソ尿素透導体及びその製法
DE2858078A DE2858078C2 (de) 1977-07-29 1978-07-21 2-Chlorethylnitrosoharnstoffe, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende pharmazeutische Zubereitungen

Publications (1)

Publication Number Publication Date
DE2858078C2 true DE2858078C2 (de) 1983-12-15

Family

ID=27519266

Family Applications (2)

Application Number Title Priority Date Filing Date
DE2858078A Expired DE2858078C2 (de) 1977-07-29 1978-07-21 2-Chlorethylnitrosoharnstoffe, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende pharmazeutische Zubereitungen
DE2832127A Expired DE2832127C2 (de) 1977-07-29 1978-07-21 1-(2-Chloräthyl)-1-nitroso-3-substituierte-3-glycosylharnstoffe, Verfahren zu deren Herstellung und diese Verbindungen enthaltende pharmazeutische Zubereitungen

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE2832127A Expired DE2832127C2 (de) 1977-07-29 1978-07-21 1-(2-Chloräthyl)-1-nitroso-3-substituierte-3-glycosylharnstoffe, Verfahren zu deren Herstellung und diese Verbindungen enthaltende pharmazeutische Zubereitungen

Country Status (21)

Country Link
US (1) US4182757A (fr)
AR (1) AR219331A1 (fr)
AT (1) AT360553B (fr)
AU (1) AU525239B2 (fr)
BE (1) BE869352A (fr)
CA (1) CA1097624A (fr)
CH (1) CH636626A5 (fr)
CS (1) CS216918B2 (fr)
DE (2) DE2858078C2 (fr)
DK (1) DK331978A (fr)
FI (1) FI65439C (fr)
FR (4) FR2403994A1 (fr)
GB (1) GB2002370B (fr)
HU (1) HU176891B (fr)
IT (1) IT1160450B (fr)
NL (1) NL7808036A (fr)
PH (1) PH13936A (fr)
PL (1) PL111784B1 (fr)
PT (1) PT68359A (fr)
SE (1) SE435501B (fr)
SU (1) SU908247A3 (fr)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4241052A (en) * 1978-06-10 1980-12-23 Tanabe Seiyaku Co., Ltd. Novel nitrosourea compounds and process for preparing the same
NL7906191A (nl) * 1978-08-25 1980-02-27 Tanabe Seiyaku Co Nieuwe nitrosoureumderivaten en de bereidingswijze daarvan.
WO1981003175A1 (fr) * 1980-05-09 1981-11-12 H Leffler Derives d'hydrate de carbone pour inhiber l'adherence bacterienne
JPS5775993A (en) * 1980-10-30 1982-05-12 Tetsuo Suami Novel nitrosourea derivative and its preparation
JPS57165398A (en) * 1981-04-02 1982-10-12 Tanabe Seiyaku Co Ltd Nitrosourea derivative and its preparation
JPS5815951A (ja) * 1981-07-21 1983-01-29 Kureha Chem Ind Co Ltd ニトロソウレア誘導体、その製法及びこの誘導体を含有する薬剤
US4656259A (en) * 1983-06-29 1987-04-07 Institut Organicheskoy Khimii Akademii Nauk Kirgizskoi Method for preparing N-alkyl-N'-glycosyl-N-nitrosourea
DE3436670A1 (de) * 1984-10-05 1986-04-10 Kangaroos U.S.A. Inc., Maryland Heights, Mo. Fussstuetze fuer fussbekleidung, insbesondere fuer schuhe
US8853284B2 (en) 2008-06-02 2014-10-07 Honeywell International Inc. Wax dispersion formulations, method of producing same, and uses
US10941111B2 (en) * 2018-10-16 2021-03-09 Purdue Research Foundation On-demand rapid synthesis of lomustine under continuous flow conditions

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3577406A (en) * 1968-05-23 1971-05-04 Upjohn Co Process for preparing the antibiotic streptozotocin
JPS4843333B1 (fr) * 1970-04-25 1973-12-18
JPS5230491B2 (fr) * 1974-07-05 1977-08-09
JPS5126876A (en) * 1974-08-08 1976-03-05 Suami T Shinkina nitorosonyosojudotaino seizohoho
IL47842A (en) * 1974-08-08 1980-07-31 Suami T Nitroso urea glycosides and related compounds,their preparation and pharmaceutical compositions containing them
US3940383A (en) * 1974-12-12 1976-02-24 Stanford Research Institute Streptozotocin analogs

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
NICHTS-ERMITTELT

Also Published As

Publication number Publication date
CH636626A5 (de) 1983-06-15
IT1160450B (it) 1987-03-11
SE7808162L (sv) 1979-01-30
FI65439B (fi) 1984-01-31
FR2485541A1 (fr) 1981-12-31
PT68359A (en) 1978-08-01
FI782215A (fi) 1979-01-30
FR2499577B1 (fr) 1984-07-13
PL111784B1 (en) 1980-09-30
DK331978A (da) 1979-01-30
BE869352A (fr) 1979-01-29
FI65439C (fi) 1984-05-10
AT360553B (de) 1981-01-26
FR2475040A1 (fr) 1981-08-07
HU176891B (en) 1981-05-28
FR2475040B1 (fr) 1984-11-16
GB2002370A (en) 1979-02-21
ATA546178A (de) 1980-06-15
SE435501B (sv) 1984-10-01
AU525239B2 (en) 1982-10-28
CA1097624A (fr) 1981-03-17
SU908247A3 (ru) 1982-02-23
FR2485541B1 (fr) 1986-06-06
FR2499577A1 (fr) 1982-08-13
US4182757A (en) 1980-01-08
AU3849178A (en) 1980-02-07
AR219331A1 (es) 1980-08-15
PL208701A1 (pl) 1979-06-04
CS216918B2 (en) 1982-12-31
DE2832127C2 (de) 1983-07-28
GB2002370B (en) 1982-03-03
PH13936A (en) 1980-11-04
NL7808036A (nl) 1979-01-31
FR2403994A1 (fr) 1979-04-20
DE2832127A1 (de) 1979-02-08
IT7868797A0 (it) 1978-07-27

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