DE2824066A1 - Neue, zur ulcusbehandlung brauchbare verbindungen, verfahren zu deren herstellung, arzneimittel und zwischenprodukte - Google Patents

Neue, zur ulcusbehandlung brauchbare verbindungen, verfahren zu deren herstellung, arzneimittel und zwischenprodukte

Info

Publication number
DE2824066A1
DE2824066A1 DE19782824066 DE2824066A DE2824066A1 DE 2824066 A1 DE2824066 A1 DE 2824066A1 DE 19782824066 DE19782824066 DE 19782824066 DE 2824066 A DE2824066 A DE 2824066A DE 2824066 A1 DE2824066 A1 DE 2824066A1
Authority
DE
Germany
Prior art keywords
acid
compound
compounds
general formula
methyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
DE19782824066
Other languages
German (de)
English (en)
Inventor
Ronnie Ray Crenshaw
George Michael Luke
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bristol Myers Co
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/848,959 external-priority patent/US4112234A/en
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of DE2824066A1 publication Critical patent/DE2824066A1/de
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C07C323/23—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
    • C07C323/39—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton at least one of the nitrogen atoms being part of any of the groups, X being a hetero atom, Y being any atom
    • C07C323/43—Y being a hetero atom
    • C07C323/44—X or Y being nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
DE19782824066 1977-06-03 1978-06-01 Neue, zur ulcusbehandlung brauchbare verbindungen, verfahren zu deren herstellung, arzneimittel und zwischenprodukte Withdrawn DE2824066A1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US80300977A 1977-06-03 1977-06-03
US82679677A 1977-08-22 1977-08-22
US05/848,959 US4112234A (en) 1977-08-22 1977-11-07 Imidazolylmethylthioethyl alkynyl guanidines

Publications (1)

Publication Number Publication Date
DE2824066A1 true DE2824066A1 (de) 1978-12-14

Family

ID=27419995

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19782824066 Withdrawn DE2824066A1 (de) 1977-06-03 1978-06-01 Neue, zur ulcusbehandlung brauchbare verbindungen, verfahren zu deren herstellung, arzneimittel und zwischenprodukte

Country Status (26)

Country Link
JP (1) JPS543067A (fi)
AR (2) AR222797A1 (fi)
CA (1) CA1110251A (fi)
CH (2) CH641167A5 (fi)
CY (3) CY1229A (fi)
DD (1) DD140038A5 (fi)
DE (1) DE2824066A1 (fi)
DK (1) DK243178A (fi)
ES (3) ES470474A1 (fi)
FI (1) FI69069C (fi)
FR (2) FR2401143A1 (fi)
GB (3) GB1598629A (fi)
GR (1) GR73860B (fi)
HK (3) HK38084A (fi)
HU (1) HU186766B (fi)
IE (1) IE47543B1 (fi)
IL (1) IL54819A (fi)
KE (1) KE3373A (fi)
LU (1) LU79725A1 (fi)
MY (3) MY8500451A (fi)
NL (1) NL7805935A (fi)
NO (3) NO152214C (fi)
NZ (1) NZ187376A (fi)
SE (3) SE443784B (fi)
SG (1) SG8584G (fi)
YU (4) YU129778A (fi)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0023578A1 (en) * 1979-07-03 1981-02-11 Shionogi & Co., Ltd. Aminoalkylbenzene derivatives, process for their preparation and pharmaceutical compositions

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4339439A (en) * 1981-01-19 1982-07-13 Bristol-Myers Company Pharmaceutical methods and compositions
JPS57134318A (en) * 1981-02-12 1982-08-19 Nissan Motor Co Ltd Air mixing construction of air conditioner
JPS5848516U (ja) * 1981-09-30 1983-04-01 日産車体株式会社 車両用空気調和装置
JPS6018010U (ja) * 1983-07-18 1985-02-07 日産自動車株式会社 車両用空気調和装置の温度調整機構
JPS60113211U (ja) * 1984-01-06 1985-07-31 松下電器産業株式会社 自動車用空気調和装置
ES2007948A6 (es) * 1988-07-06 1989-07-01 Vinas Lab Procedimiento para la obtencion de derivados propargilguanidicos.

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2344779A1 (de) * 1972-09-05 1974-03-14 Smith Kline French Lab Cyanguanidine, ihre salze, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
BE832663A (fr) * 1974-09-02 1976-02-23 Procede perfectionne de preparation de thiourees et de guanidines et produits obtenus

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1338169A (en) * 1971-03-09 1973-11-21 Smith Kline French Lab Ureas thioureas and guanidines
US4024271A (en) * 1971-03-09 1977-05-17 Smith Kline & French Laboratories Limited Pharmacologically active guanidine compounds
GB1531221A (en) * 1974-09-02 1978-11-08 Smith Kline French Lab Process for preparing guanidine derivatives
GB1531231A (en) * 1974-09-02 1978-11-08 Smith Kline French Lab Process for the production of cyanoguanidine derivatives

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2344779A1 (de) * 1972-09-05 1974-03-14 Smith Kline French Lab Cyanguanidine, ihre salze, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
BE832663A (fr) * 1974-09-02 1976-02-23 Procede perfectionne de preparation de thiourees et de guanidines et produits obtenus

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0023578A1 (en) * 1979-07-03 1981-02-11 Shionogi & Co., Ltd. Aminoalkylbenzene derivatives, process for their preparation and pharmaceutical compositions

Also Published As

Publication number Publication date
NO791637L (no) 1978-12-05
CH641167A5 (en) 1984-02-15
CY1230A (en) 1984-06-29
YU40624B (en) 1986-02-28
DK243178A (da) 1978-12-04
HK38084A (en) 1984-05-11
HK38184A (en) 1984-05-11
AR222503A1 (es) 1981-05-29
FR2436138B1 (fi) 1982-12-03
FI69069C (fi) 1985-12-10
IE781112L (en) 1978-12-03
IE47543B1 (en) 1984-04-18
YU40625B (en) 1986-02-28
NO152214C (no) 1985-08-28
MY8500452A (en) 1985-12-31
YU41620B (en) 1987-12-31
YU53079A (en) 1983-09-30
IL54819A (en) 1983-03-31
SE8401492D0 (sv) 1984-03-16
LU79725A1 (fr) 1979-02-02
GR73860B (fi) 1984-05-08
NO781928L (no) 1978-12-05
YU215582A (en) 1983-02-28
ES470474A1 (es) 1979-09-01
NO151824C (no) 1985-06-12
SE8401491L (sv) 1984-03-16
JPS5639313B2 (fi) 1981-09-11
SE8401491D0 (sv) 1984-03-16
AR222797A1 (es) 1981-06-30
NO151824B (no) 1985-03-04
SE443784B (sv) 1986-03-10
CY1229A (en) 1984-06-29
ES478203A1 (es) 1979-06-01
MY8500451A (en) 1985-12-31
GB1598629A (en) 1981-09-23
YU215482A (en) 1983-02-28
IL54819A0 (en) 1978-07-31
KE3373A (en) 1984-03-23
FR2401143A1 (fr) 1979-03-23
CA1110251A (en) 1981-10-06
SE8401492L (sv) 1984-03-16
NL7805935A (nl) 1978-12-05
SG8584G (en) 1985-02-08
FI781737A (fi) 1978-12-04
FR2436138A1 (fr) 1980-04-11
HK38284A (en) 1984-05-11
MY8500453A (en) 1985-12-31
FI69069B (fi) 1985-08-30
SE7806525A (sv) 1978-12-04
GB1598628A (en) 1981-09-23
GB1598630A (en) 1981-09-23
JPS543067A (en) 1979-01-11
SE7806525L (sv) 1978-12-04
CY1231A (en) 1984-06-29
HU186766B (en) 1985-09-30
NZ187376A (en) 1981-05-29
YU129778A (en) 1983-02-28
CH644591A5 (en) 1984-08-15
DD140038A5 (de) 1980-02-06
NO152214B (no) 1985-05-13
FR2401143B1 (fi) 1981-12-11
ES478202A1 (es) 1979-06-01
NO833255L (no) 1978-12-05

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