DE2423390A1 - Pyroglutamylverbindungen mit antidepressiver wirkung und verfahren zu ihrer herstellung - Google Patents

Pyroglutamylverbindungen mit antidepressiver wirkung und verfahren zu ihrer herstellung

Info

Publication number
DE2423390A1
DE2423390A1 DE2423390A DE2423390A DE2423390A1 DE 2423390 A1 DE2423390 A1 DE 2423390A1 DE 2423390 A DE2423390 A DE 2423390A DE 2423390 A DE2423390 A DE 2423390A DE 2423390 A1 DE2423390 A1 DE 2423390A1
Authority
DE
Germany
Prior art keywords
optionally
compounds
acid
carbon atoms
branched alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
DE2423390A
Other languages
German (de)
English (en)
Inventor
Rolf Dr Geiger
Wolfgang Dr Koenig
Hans-Joerg Dr Kruse
Michel Dr Peterfalvi
Hans Dr Wissmann
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hoechst AG
Original Assignee
Hoechst AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst AG filed Critical Hoechst AG
Priority to DE2423390A priority Critical patent/DE2423390A1/de
Priority to IL47258A priority patent/IL47258A/xx
Priority to NL7505473A priority patent/NL7505473A/xx
Priority to CH85079A priority patent/CH613689A5/xx
Priority to CH608075A priority patent/CH612180A5/xx
Priority to GB1984075A priority patent/GB1472154A/en
Priority to LU72450A priority patent/LU72450A1/xx
Priority to AT364875A priority patent/AT352707B/de
Priority to CA227,255A priority patent/CA1064942A/fr
Priority to DK209575A priority patent/DK209575A/da
Priority to IE1069/75A priority patent/IE41145B1/xx
Priority to BE156337A priority patent/BE829059A/fr
Priority to JP50056232A priority patent/JPS50157362A/ja
Priority to FR7515026A priority patent/FR2270866B1/fr
Priority to SE7505546A priority patent/SE405113B/xx
Publication of DE2423390A1 publication Critical patent/DE2423390A1/de
Priority to AT64078A priority patent/AT357279B/de
Priority to AT0013179A priority patent/AT364875B/de
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06—Esters of carbamic acids
    • C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
    • C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C271/22—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by carboxyl groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • C07D207/273—2-Pyrrolidones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
    • C07D207/277—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D207/28—2-Pyrrolidone-5- carboxylic acids; Functional derivatives thereof, e.g. esters, nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06139—Dipeptides with the first amino acid being heterocyclic
    • C07K5/06173—Dipeptides with the first amino acid being heterocyclic and Glp-amino acid; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pyrrole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE2423390A 1974-05-14 1974-05-14 Pyroglutamylverbindungen mit antidepressiver wirkung und verfahren zu ihrer herstellung Withdrawn DE2423390A1 (de)

Priority Applications (17)

Application Number Priority Date Filing Date Title
DE2423390A DE2423390A1 (de) 1974-05-14 1974-05-14 Pyroglutamylverbindungen mit antidepressiver wirkung und verfahren zu ihrer herstellung
IL47258A IL47258A (en) 1974-05-14 1975-05-08 Pyroglutamyl compounds having antidepressive activity and process for their manufacture
NL7505473A NL7505473A (nl) 1974-05-14 1975-05-09 Werkwijze voor het bereiden van pyroglutamylver- bindingen met antidepressieve werking.
CH85079A CH613689A5 (en) 1974-05-14 1975-05-12 Process for the preparation of novel pyroglutamyl compounds
CH608075A CH612180A5 (en) 1974-05-14 1975-05-12 Process for the preparation of novel pyroglutamyl compounds
GB1984075A GB1472154A (en) 1974-05-14 1975-05-12 Pyroglutamyl compounds and process for their manufacture
LU72450A LU72450A1 (fr) 1974-05-14 1975-05-12
DK209575A DK209575A (da) 1974-05-14 1975-05-13 Pyroglutamylforbindelser med antidepressiv virkning og fremgangsmade til deres fremstilling
CA227,255A CA1064942A (fr) 1974-05-14 1975-05-13 Composes de pyroglutamy antidepresseurs et procede de fabrication
AT364875A AT352707B (de) 1974-05-14 1975-05-13 Verfahren zur herstellung von neuen pyroglutamylverbindungen
IE1069/75A IE41145B1 (en) 1974-05-14 1975-05-13 Pyroglutamyl compounds and process for their manufacture
BE156337A BE829059A (fr) 1974-05-14 1975-05-14 Derives de pyroglutamyle leur procede de preparation et leurs applications
JP50056232A JPS50157362A (fr) 1974-05-14 1975-05-14
FR7515026A FR2270866B1 (fr) 1974-05-14 1975-05-14
SE7505546A SE405113B (sv) 1974-05-14 1975-05-14 Forfarande for framstellning av pyroglutamylforeningar med antidepressiv verkan
AT64078A AT357279B (de) 1974-05-14 1978-01-30 Verfahren zur herstellung von neuen pyroglutamylverbindungen
AT0013179A AT364875B (de) 1974-05-14 1979-01-08 Fluessiges reinigungsmittel

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2423390A DE2423390A1 (de) 1974-05-14 1974-05-14 Pyroglutamylverbindungen mit antidepressiver wirkung und verfahren zu ihrer herstellung

Publications (1)

Publication Number Publication Date
DE2423390A1 true DE2423390A1 (de) 1975-12-04

Family

ID=5915523

Family Applications (1)

Application Number Title Priority Date Filing Date
DE2423390A Withdrawn DE2423390A1 (de) 1974-05-14 1974-05-14 Pyroglutamylverbindungen mit antidepressiver wirkung und verfahren zu ihrer herstellung

Country Status (14)

Country Link
JP (1) JPS50157362A (fr)
AT (2) AT352707B (fr)
BE (1) BE829059A (fr)
CA (1) CA1064942A (fr)
CH (2) CH613689A5 (fr)
DE (1) DE2423390A1 (fr)
DK (1) DK209575A (fr)
FR (1) FR2270866B1 (fr)
GB (1) GB1472154A (fr)
IE (1) IE41145B1 (fr)
IL (1) IL47258A (fr)
LU (1) LU72450A1 (fr)
NL (1) NL7505473A (fr)
SE (1) SE405113B (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1024134A1 (fr) * 1997-10-09 2000-08-02 Ono Pharmaceutical Co., Ltd. Derives d'acide aminobutanoique

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5840667A (en) * 1994-08-05 1998-11-24 Warwick International Group, Ltd. Bleach activators
RU2232578C1 (ru) * 2003-04-10 2004-07-20 Ахапкина Валентина Ивановна Вещество, обладающее антидепрессивной активностью

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5220996B2 (fr) * 1972-01-14 1977-06-07
JPS5015793B2 (fr) * 1972-06-07 1975-06-07

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1024134A1 (fr) * 1997-10-09 2000-08-02 Ono Pharmaceutical Co., Ltd. Derives d'acide aminobutanoique
EP1024134A4 (fr) * 1997-10-09 2003-05-14 Ono Pharmaceutical Co Derives d'acide aminobutanoique

Also Published As

Publication number Publication date
ATA364875A (de) 1979-03-15
FR2270866B1 (fr) 1978-08-04
GB1472154A (en) 1977-05-04
JPS50157362A (fr) 1975-12-19
SE405113B (sv) 1978-11-20
DK209575A (da) 1975-11-15
FR2270866A1 (fr) 1975-12-12
CH612180A5 (en) 1979-07-13
BE829059A (fr) 1975-11-14
IL47258A (en) 1978-07-31
CH613689A5 (en) 1979-10-15
AT352707B (de) 1979-10-10
AT364875B (de) 1979-03-15
NL7505473A (nl) 1975-11-18
SE7505546L (sv) 1975-11-17
IE41145L (en) 1975-11-14
ATA13179A (de) 1981-04-15
IE41145B1 (en) 1979-10-24
IL47258A0 (en) 1975-07-28
LU72450A1 (fr) 1977-02-09
CA1064942A (fr) 1979-10-23

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Date Code Title Description
8130 Withdrawal