DE2416193C2 - Prostaglandin-Analoge, Verfahren zu ihrer Herstellung sowie ihre Verwendung als cytoprotektives Mittel - Google Patents

Prostaglandin-Analoge, Verfahren zu ihrer Herstellung sowie ihre Verwendung als cytoprotektives Mittel

Info

Publication number
DE2416193C2
DE2416193C2 DE2416193A DE2416193A DE2416193C2 DE 2416193 C2 DE2416193 C2 DE 2416193C2 DE 2416193 A DE2416193 A DE 2416193A DE 2416193 A DE2416193 A DE 2416193A DE 2416193 C2 DE2416193 C2 DE 2416193C2
Authority
DE
Germany
Prior art keywords
formula
compound
same meaning
acid
dimethyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE2416193A
Other languages
German (de)
English (en)
Other versions
DE2416193A1 (de
Inventor
Milo Dr. 6000 Frankfurt Babej
Gerhard Dr. 6000 Frankfurt Beck
Rudolf Dr. 6238 Hofheim Kunstmann
Hermann Dr. 6233 Kelkheim Teufel
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hoechst AG
Original Assignee
Hoechst AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst AG filed Critical Hoechst AG
Priority to DE19742463432 priority Critical patent/DE2463432C2/de
Priority to DE2416193A priority patent/DE2416193C2/de
Priority to NL7503727A priority patent/NL7503727A/xx
Priority to AU79622/75A priority patent/AU501389B2/en
Priority to ES436117A priority patent/ES436117A1/es
Priority to IL46962A priority patent/IL46962A0/xx
Priority to CH408775A priority patent/CH618968A5/de
Priority to LU72179A priority patent/LU72179A1/xx
Priority to US05/563,973 priority patent/US4061671A/en
Priority to HU75HO1788A priority patent/HU174005B/hu
Priority to DK140375A priority patent/DK140375A/da
Priority to CA223,705A priority patent/CA1042880A/en
Priority to AT251375A priority patent/AT356297B/de
Priority to ZA00752045A priority patent/ZA752045B/xx
Priority to FR7510389A priority patent/FR2266499B1/fr
Priority to SE7503812A priority patent/SE7503812L/xx
Priority to JP50040748A priority patent/JPS5854140B2/ja
Priority to GB13698/75A priority patent/GB1511261A/en
Priority to BE155063A priority patent/BE827529A/xx
Publication of DE2416193A1 publication Critical patent/DE2416193A1/de
Application granted granted Critical
Publication of DE2416193C2 publication Critical patent/DE2416193C2/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
    • C07D307/935—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/10—Oxygen atoms
    • C07D309/12—Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Furan Compounds (AREA)
  • Pyrane Compounds (AREA)
DE2416193A 1974-04-03 1974-04-03 Prostaglandin-Analoge, Verfahren zu ihrer Herstellung sowie ihre Verwendung als cytoprotektives Mittel Expired DE2416193C2 (de)

Priority Applications (19)

Application Number Priority Date Filing Date Title
DE19742463432 DE2463432C2 (en:Method) 1974-04-03 1974-04-03
DE2416193A DE2416193C2 (de) 1974-04-03 1974-04-03 Prostaglandin-Analoge, Verfahren zu ihrer Herstellung sowie ihre Verwendung als cytoprotektives Mittel
NL7503727A NL7503727A (nl) 1974-04-03 1975-03-27 Werkwijze voor het bereiden van nieuwe prostaglandine-analoga.
AU79622/75A AU501389B2 (en) 1974-04-03 1975-03-27 Prostaglandin analogues
ES436117A ES436117A1 (es) 1974-04-03 1975-03-27 Procedimiento para la preparacion de nuevos compuestos ana- logos de acidos prostanoicos que no se presentan en la natu-raleza.
IL46962A IL46962A0 (en) 1974-04-03 1975-03-28 New analogues of prostaglandins and process for their manufacture
LU72179A LU72179A1 (en:Method) 1974-04-03 1975-04-01
US05/563,973 US4061671A (en) 1974-04-03 1975-04-01 Analogues of prostaglandins
CH408775A CH618968A5 (en:Method) 1974-04-03 1975-04-01
CA223,705A CA1042880A (en) 1974-04-03 1975-04-02 Analogues of prostaglandins and process for their manufacture
HU75HO1788A HU174005B (hu) 1974-04-03 1975-04-02 Sposob poluchenija proizvodnykh analogov prostaglandina
AT251375A AT356297B (de) 1974-04-03 1975-04-02 Verfahren zur herstellung von neuen prostaglandin-analogen
ZA00752045A ZA752045B (en) 1974-04-03 1975-04-02 New analogues of prostaglandins and process for their manufacture
DK140375A DK140375A (en:Method) 1974-04-03 1975-04-02
SE7503812A SE7503812L (sv) 1974-04-03 1975-04-03 Nya prostaglandinanaloger och forfarande for deras framstellning.
FR7510389A FR2266499B1 (en:Method) 1974-04-03 1975-04-03
JP50040748A JPS5854140B2 (ja) 1974-04-03 1975-04-03 シンキプロスタグランジンルイエンタイノセイホウ
GB13698/75A GB1511261A (en) 1974-04-03 1975-04-03 Analogues of prostaglandins and process for their manufacture
BE155063A BE827529A (fr) 1974-04-03 1975-04-03 Nouveaux analogues de prostaglandines, leur procede de preparation et leurs applications

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2416193A DE2416193C2 (de) 1974-04-03 1974-04-03 Prostaglandin-Analoge, Verfahren zu ihrer Herstellung sowie ihre Verwendung als cytoprotektives Mittel

Publications (2)

Publication Number Publication Date
DE2416193A1 DE2416193A1 (de) 1975-10-23
DE2416193C2 true DE2416193C2 (de) 1985-08-14

Family

ID=5912040

Family Applications (1)

Application Number Title Priority Date Filing Date
DE2416193A Expired DE2416193C2 (de) 1974-04-03 1974-04-03 Prostaglandin-Analoge, Verfahren zu ihrer Herstellung sowie ihre Verwendung als cytoprotektives Mittel

Country Status (18)

Country Link
US (1) US4061671A (en:Method)
JP (1) JPS5854140B2 (en:Method)
AT (1) AT356297B (en:Method)
AU (1) AU501389B2 (en:Method)
BE (1) BE827529A (en:Method)
CA (1) CA1042880A (en:Method)
CH (1) CH618968A5 (en:Method)
DE (1) DE2416193C2 (en:Method)
DK (1) DK140375A (en:Method)
ES (1) ES436117A1 (en:Method)
FR (1) FR2266499B1 (en:Method)
GB (1) GB1511261A (en:Method)
HU (1) HU174005B (en:Method)
IL (1) IL46962A0 (en:Method)
LU (1) LU72179A1 (en:Method)
NL (1) NL7503727A (en:Method)
SE (1) SE7503812L (en:Method)
ZA (1) ZA752045B (en:Method)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2946756A1 (de) * 1979-11-20 1981-05-27 Hoechst Ag, 6000 Frankfurt Stickstoff-haltige prostaglandin/prostacyclin-synthone und verfahren zu ihrer herstellung

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4098815A (en) * 1974-02-15 1978-07-04 Hoechst Aktiengesellschaft Novel analogues of prostanoic acids not occurring in nature
DK142235B (da) * 1974-12-20 1980-09-29 Yamanouchi Pharma Co Ltd Analogifremgangsmåde til fremstilling af 20-alkoxy-16-methyl-prostadiensyre-derivater.
US4169895A (en) * 1976-09-28 1979-10-02 Pfizer Inc. Antisecretory 16,16-dimethyl-17-oxaprostaglandins
JPS62188834U (en:Method) * 1986-05-20 1987-12-01
JPS648844U (en:Method) * 1987-07-07 1989-01-18
JPS648845U (en:Method) * 1987-07-07 1989-01-18
JPH08307284A (ja) * 1995-04-28 1996-11-22 Nec Shizuoka Ltd ロック機構付き発信機用ケースの防水構造
KR20010108316A (ko) 1999-03-05 2001-12-07 데이비드 엠 모이어 Ｃ16 불포화된 ｆｐ-선택적 프로스타글란딘 유사체
US6894175B1 (en) * 1999-08-04 2005-05-17 The Procter & Gamble Company 2-Decarboxy-2-phosphinico prostaglandin derivatives and methods for their preparation and use
US20020037914A1 (en) * 2000-03-31 2002-03-28 Delong Mitchell Anthony Compositions and methods for treating hair loss using C16-C20 aromatic tetrahydro prostaglandins
US20020172693A1 (en) 2000-03-31 2002-11-21 Delong Michell Anthony Compositions and methods for treating hair loss using non-naturally occurring prostaglandins
US20020013294A1 (en) 2000-03-31 2002-01-31 Delong Mitchell Anthony Cosmetic and pharmaceutical compositions and methods using 2-decarboxy-2-phosphinico derivatives
US8623918B2 (en) 2008-10-29 2014-01-07 Novaer Holdings, Inc. Amino acid salts of prostaglandins
US8722739B2 (en) 2008-10-29 2014-05-13 Novaer Holdings, Inc. Amino acid salts of prostaglandins

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS503362B1 (en:Method) * 1970-06-10 1975-02-04
BE786250A (fr) * 1971-07-14 1973-01-15 Ici Ltd Derives du cyclopentane
NL7209738A (en) * 1972-07-13 1974-01-15 Alkenyl succinic anhydrides - useful as washing agent builders

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2946756A1 (de) * 1979-11-20 1981-05-27 Hoechst Ag, 6000 Frankfurt Stickstoff-haltige prostaglandin/prostacyclin-synthone und verfahren zu ihrer herstellung

Also Published As

Publication number Publication date
BE827529A (fr) 1975-10-03
AU501389B2 (en) 1979-06-21
GB1511261A (en) 1978-05-17
AU7962275A (en) 1976-09-30
ES436117A1 (es) 1977-05-01
FR2266499A1 (en:Method) 1975-10-31
ATA251375A (de) 1979-09-15
JPS50137959A (en:Method) 1975-11-01
CH618968A5 (en:Method) 1980-08-29
AT356297B (de) 1980-04-25
FR2266499B1 (en:Method) 1978-11-10
IL46962A0 (en) 1975-05-22
DE2416193A1 (de) 1975-10-23
US4061671A (en) 1977-12-06
ZA752045B (en) 1976-03-31
LU72179A1 (en:Method) 1977-02-01
JPS5854140B2 (ja) 1983-12-02
SE7503812L (sv) 1975-10-06
CA1042880A (en) 1978-11-21
DK140375A (en:Method) 1975-10-04
NL7503727A (nl) 1975-10-07
HU174005B (hu) 1979-10-28

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