DE2351739C3 - 1- [3-(4-m-Chlorphenyl-piperazino)-propyl] -3,4diäthyl- A2 -1,2,4- triazolin-5-on - Google Patents

1- [3-(4-m-Chlorphenyl-piperazino)-propyl] -3,4diäthyl- A2 -1,2,4- triazolin-5-on

Info

Publication number
DE2351739C3
DE2351739C3 DE2351739A DE2351739A DE2351739C3 DE 2351739 C3 DE2351739 C3 DE 2351739C3 DE 2351739 A DE2351739 A DE 2351739A DE 2351739 A DE2351739 A DE 2351739A DE 2351739 C3 DE2351739 C3 DE 2351739C3
Authority
DE
Germany
Prior art keywords
triazolin
acid
diethyl
chlorophenyl
propyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE2351739A
Other languages
German (de)
English (en)
Other versions
DE2351739B2 (de
DE2351739A1 (de
Inventor
Giuseppe Rom Palazzo
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Angelini Acraf SpA
Original Assignee
Aziende Chimiche Riunite Angelini Francesco ACRAF SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aziende Chimiche Riunite Angelini Francesco ACRAF SpA filed Critical Aziende Chimiche Riunite Angelini Francesco ACRAF SpA
Publication of DE2351739A1 publication Critical patent/DE2351739A1/de
Publication of DE2351739B2 publication Critical patent/DE2351739B2/de
Application granted granted Critical
Publication of DE2351739C3 publication Critical patent/DE2351739C3/de
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D249/00Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/081,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C07D249/101,2,4-Triazoles; Hydrogenated 1,2,4-triazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D249/12Oxygen or sulfur atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/08Antiepileptics; Anticonvulsants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D249/00Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/081,2,4-Triazoles; Hydrogenated 1,2,4-triazoles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Anesthesiology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
DE2351739A 1972-10-16 1973-10-15 1- [3-(4-m-Chlorphenyl-piperazino)-propyl] -3,4diäthyl- A2 -1,2,4- triazolin-5-on Expired DE2351739C3 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT53380/72A IT1052119B (it) 1972-10-16 1972-10-16 Derivati del triazolinone e procedimento per la loro preparazione

Publications (3)

Publication Number Publication Date
DE2351739A1 DE2351739A1 (de) 1974-04-18
DE2351739B2 DE2351739B2 (de) 1980-01-10
DE2351739C3 true DE2351739C3 (de) 1980-09-04

Family

ID=11282276

Family Applications (1)

Application Number Title Priority Date Filing Date
DE2351739A Expired DE2351739C3 (de) 1972-10-16 1973-10-15 1- [3-(4-m-Chlorphenyl-piperazino)-propyl] -3,4diäthyl- A2 -1,2,4- triazolin-5-on

Country Status (19)

Country Link
US (1) US3857845A (US07642317-20100105-C00010.png)
JP (1) JPS5550948B2 (US07642317-20100105-C00010.png)
AR (1) AR204086A1 (US07642317-20100105-C00010.png)
AT (1) AT336021B (US07642317-20100105-C00010.png)
BE (1) BE806146A (US07642317-20100105-C00010.png)
CA (1) CA1013746A (US07642317-20100105-C00010.png)
CH (1) CH589643A5 (US07642317-20100105-C00010.png)
DE (1) DE2351739C3 (US07642317-20100105-C00010.png)
DK (1) DK141750B (US07642317-20100105-C00010.png)
ES (1) ES419687A1 (US07642317-20100105-C00010.png)
FI (1) FI58495C (US07642317-20100105-C00010.png)
FR (1) FR2202702B1 (US07642317-20100105-C00010.png)
GB (1) GB1438337A (US07642317-20100105-C00010.png)
IT (1) IT1052119B (US07642317-20100105-C00010.png)
KE (1) KE2823A (US07642317-20100105-C00010.png)
NL (1) NL184782C (US07642317-20100105-C00010.png)
NO (1) NO138565C (US07642317-20100105-C00010.png)
SE (1) SE390819B (US07642317-20100105-C00010.png)
YU (1) YU39914B (US07642317-20100105-C00010.png)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1047702B (it) * 1975-07-24 1980-10-20 Acraf Nuova sintesi degli psicofarmaci denominati trazodone ed eteroperidone
US4162318A (en) * 1976-05-05 1979-07-24 Aziende Chimiche Riunite Angelini Francesco A.C.R.A.F. S.P.A. Use of trazodone and etoperidone in Parkinsonism and in other extrapyramidal syndromes characterized by tremors
IT1073639B (it) * 1976-05-05 1985-04-17 Acraf Impiego del trazodone e etoperidone nel morbo di parikinson ed in altre sindromi extrapiramidali caratterizzate da tremori
US4465683A (en) * 1979-09-14 1984-08-14 Mead Johnson & Company Anti-psychotic agents
US4254124A (en) * 1979-09-24 1981-03-03 Mead Johnson & Company Antidepressant agent
US4338317A (en) * 1981-03-16 1982-07-06 Mead Johnson & Company Phenoxyethyl-1,2,4,-triazol-3-one antidepressants
US4487773A (en) * 1981-03-16 1984-12-11 Mead Johnson & Company 1,2,4-Triazol-3-one antidepressants
US4367335A (en) * 1981-08-03 1983-01-04 Mead Johnson & Company Thiazolidinylalkylene piperazine derivatives
US4386091A (en) * 1982-02-24 1983-05-31 Mead Johnson & Company 2-Phenoxyalkyl-1,2,4-triazol-3-one antidepressants
US4575555A (en) * 1983-06-29 1986-03-11 Mead Johnson & Company 4-(3-Chlorophenyl)-1,2,3,6-tetrahydropyridine derivative
US4613600A (en) * 1983-09-30 1986-09-23 Mead Johnson & Company Antidepressant 1,2,4-triazolone compounds
US4784998A (en) * 1987-04-06 1988-11-15 Bristol-Myers Company 1,3,4-oxadiazole pyschotropic compounds
US4931445A (en) * 1988-10-06 1990-06-05 Irwin Goldstein Agents for treatment of male impotence
US5229406A (en) * 1990-09-19 1993-07-20 G. D. Searle & Co. 1,3,5-trisubstituted-1,2,4-triazole compounds for treatment of circulatory disorders
US5140036A (en) * 1990-09-19 1992-08-18 G. D. Searle & Co. 1,3,5-trisubstituted-1,2,4-triazole compounds for treatment of circulatory disorders
US5087634A (en) * 1990-10-31 1992-02-11 G. D. Searle & Co. N-substituted imidazol-2-one compounds for treatment of circulatory disorders
US5238952A (en) * 1990-10-31 1993-08-24 G. D. Searle & Co. N-substituted imidazol-2-one compounds for treatment of circulatory disorders
US5196537A (en) * 1991-03-21 1993-03-23 G. D. Searle & Co. 5-apylheteroarylalkyl-1,3,5-trisubstituted-1,2,4-triazole compounds for treatment of circulatory disorders
US5164403A (en) * 1991-04-05 1992-11-17 G. D. Searle & Co. N-arylheteroarylalkyl imidazol-2-one compounds for treatment of circulatory disorders
IT1256387B (it) * 1992-11-13 1995-12-04 Acraf Procedimento per preparare triazoloni
CA2182241C (en) * 1996-07-29 2002-09-17 Bo Lei Methods for the manufacture of nefazodone
ES2152860B1 (es) * 1998-10-23 2001-08-16 Finaf 92 Sa Forma cristalina de la nefazodona y procedimiento para su preparacion.
WO2012072665A1 (en) 2010-11-30 2012-06-07 Pharmaneuroboost N.V. Compositions comprising pipamperone and serotonin antagonist reuptake inhibitors

Also Published As

Publication number Publication date
DK141750C (US07642317-20100105-C00010.png) 1980-11-03
ATA871173A (de) 1976-08-15
AT336021B (de) 1977-04-12
NL184782C (nl) 1989-11-01
FI58495B (fi) 1980-10-31
NL7314204A (US07642317-20100105-C00010.png) 1974-04-18
AR204086A1 (es) 1975-11-20
DE2351739B2 (de) 1980-01-10
SE390819B (sv) 1977-01-24
IT1052119B (it) 1981-06-20
BE806146A (fr) 1974-02-15
NO138565C (no) 1978-09-27
YU263473A (en) 1983-02-28
JPS4993381A (US07642317-20100105-C00010.png) 1974-09-05
US3857845A (en) 1974-12-31
NL184782B (nl) 1989-06-01
DK141750B (da) 1980-06-09
YU39914B (en) 1985-06-30
CA1013746A (en) 1977-07-12
JPS5550948B2 (US07642317-20100105-C00010.png) 1980-12-20
FR2202702A1 (US07642317-20100105-C00010.png) 1974-05-10
NO138565B (no) 1978-06-19
FI58495C (fi) 1981-02-10
ES419687A1 (es) 1976-10-16
GB1438337A (US07642317-20100105-C00010.png) 1976-06-03
KE2823A (en) 1978-03-31
FR2202702B1 (US07642317-20100105-C00010.png) 1976-07-02
DE2351739A1 (de) 1974-04-18
CH589643A5 (US07642317-20100105-C00010.png) 1977-07-15

Similar Documents

Publication Publication Date Title
DE2351739C3 (de) 1- [3-(4-m-Chlorphenyl-piperazino)-propyl] -3,4diäthyl- A2 -1,2,4- triazolin-5-on
DE1543715C3 (de) Basisch substituierte Phthalanderivate und deren pharmakologisch verträgliche Säureadditionssalze sowie Verfahren zu deren Herstellung
CH656383A5 (de) 2-(4-(4-(4,4-dialkyl-2,6-piperidindion-1-yl)-butyl)-1-piperazinyl)pyrimidine.
DE2707068A1 (de) Neue chinazoline, verfahren zu deren herstellung und daraus hergestellte arzneimittel
DE2238504C3 (de) l-Phenoxy-S-alkylaminopropan^-ol -Derivate
DE2037852B2 (de) Neue Piperazinderivate und Verfahren zu ihrer Herstellung
DE2713441A1 (de) Amidinoharnstoffe
DE2426149C3 (de) 7-Fluor-substituierte Phenothiazine, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Mittel
DE2167193C2 (de) 4-(4-Hydroxypiperidino)-N,N,3-trimethyl-2,2-diphenylbutyramide und Verfahren zu ihrer Herstellung
DE1964515A1 (de) 1-Substituierte-4-Phenoxypiperidine und Verfahren zu ihrer Herstellung
DE1940566C3 (de) 1- (2-Nitrilophenoxy)-2-hydroxy-3äthylaminopropan, Verfahren zu dessen Herstellung und dieses enthaltende Arzneimittel
DE2716838A1 (de) Thioharnstoffderivate
DE2724478C2 (de) 5,11-Dihydro-6H-pyrido[2,3-b][1,4]benzodiazepin-6-on-derivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
DE2107871C3 (US07642317-20100105-C00010.png)
EP0177907B1 (de) Neue 2-Pyridin-thiol-Derivate, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Präparate
DE2425767A1 (de) 3-alkyl-9-aminoalkyl-1,2,3,4-tetrahydrocarbazole und ihre verwendung in arzneimitteln
DE2144077C3 (de) Neue Hydroxyäthylaminoalkylpiperazine und Verfahren zu deren Herstellung
DE2000775B2 (de) Substituierte 1,2,3,4-Tetrahydrobenzothieno [23-c] pyridin-Verbindungen, Verfahren zu ihrer Herstellung und pharmazeutische Zubereitung, die diese Verbindungen enthält
DE1922280C3 (de) l-Methyl-5-(3'-dimethylaminopropyliden)-5Hdibenzo [a,d] -cyelohepten-N- oxid und dessen Säureadditionssalze, sowie Verfahren zu deren Herstellung und diese Verbindungen enthaltende Präparate
DE1217396B (de) Verfahren zur Herstellung von 1 - (Thienyl-21) - l-oxo-2-amino-propanen
DE2139099C3 (de) l-Methyl-2-(p-methyl- a -phenylbenzyloxymethyl)piperidin, seine Salze mit Säuren und quartäre Ammoniumsalze, Verfahren zur Herstellung dieser Verbindungen und Arzneimittel
DE2251095C3 (de) 1,4-Methano- und 1,4-Äthano-tetrahydronaphthyloxypropanole, Verfahren zu ihrer Herstellung und diese enthaltende Arzneimittel
AT281812B (de) Verfahren zur herstellung von neuen 2,3-dihydrobenzofuranderivaten und ihren salzen
DE1445959C (de) alpha NaphthyK1 )-propionsäurediester von N,N-Bis-(beta-hydroxyäthyl)piperazin, dessen Salze mit physiologisch verträglichen Säuren.und Verfahren zu ihrer Herstellung
DE2039694C3 (de) Imidazolidinonderivate, Verfahren zu ihrer Herstellung sowie Arzneimittel

Legal Events

Date Code Title Description
C3 Grant after two publication steps (3rd publication)