IT1256387B - Procedimento per preparare triazoloni - Google Patents
Procedimento per preparare triazoloniInfo
- Publication number
- IT1256387B IT1256387B ITMI922604A ITMI922604A IT1256387B IT 1256387 B IT1256387 B IT 1256387B IT MI922604 A ITMI922604 A IT MI922604A IT MI922604 A ITMI922604 A IT MI922604A IT 1256387 B IT1256387 B IT 1256387B
- Authority
- IT
- Italy
- Prior art keywords
- alkyl
- triazoloni
- preparing
- procedure
- substituted
- Prior art date
Links
- -1 alkyl radical Chemical class 0.000 abstract 3
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 150000005840 aryl radicals Chemical class 0.000 abstract 2
- MDTUWBLTRPRXBX-UHFFFAOYSA-N 1,2,4-triazol-3-one Chemical group O=C1N=CN=N1 MDTUWBLTRPRXBX-UHFFFAOYSA-N 0.000 abstract 1
- 150000007933 aliphatic carboxylic acids Chemical class 0.000 abstract 1
- WPYMKLBDIGXBTP-UHFFFAOYSA-N benzoic acid Chemical compound OC(=O)C1=CC=CC=C1 WPYMKLBDIGXBTP-UHFFFAOYSA-N 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
- C07D249/10—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D249/12—Oxygen or sulfur atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Preparazione di un 1,2,4-triazol-3-one sostituito in posizione 4 e 5 da un radicale alchilico o arilico ed, eventualmente, in posizione 2 da un radicale alchilico, mediante reazione di un estere di un acido carbammico N-sostituito da un radicale alchilico od arilico con un'idrazide di un acido carbossilico alifatico od aromatico, eventualmente N-sostituita da un radicale alchilico, in presenza di una base forte.
Priority Applications (9)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ITMI922604A IT1256387B (it) | 1992-11-13 | 1992-11-13 | Procedimento per preparare triazoloni |
PCT/EP1993/003119 WO1994011357A1 (en) | 1992-11-13 | 1993-11-06 | Process for the preparation of triazolone compounds |
AT94900112T ATE163414T1 (de) | 1992-11-13 | 1993-11-06 | Verfahren zur herstellung von triazolonderivaten |
US08/424,477 US5767275A (en) | 1992-11-13 | 1993-11-06 | Preparation of triazolone compounds |
DE69317122T DE69317122T2 (de) | 1992-11-13 | 1993-11-06 | Verfahren zur herstellung von triazolonderivaten |
EP94900112A EP0668857B1 (en) | 1992-11-13 | 1993-11-06 | Process for the preparation of triazolone compounds |
AU54643/94A AU5464394A (en) | 1992-11-13 | 1993-11-06 | Process for the preparation of triazolone compounds |
DK94900112T DK0668857T3 (da) | 1992-11-13 | 1993-11-06 | Fremgangsmåde til fremstilling af triazolonforbindelser |
ES94900112T ES2115916T3 (es) | 1992-11-13 | 1993-11-06 | Procedimiento para la preparacion de compuestos de triazolona. |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ITMI922604A IT1256387B (it) | 1992-11-13 | 1992-11-13 | Procedimento per preparare triazoloni |
Publications (3)
Publication Number | Publication Date |
---|---|
ITMI922604A0 ITMI922604A0 (it) | 1992-11-13 |
ITMI922604A1 ITMI922604A1 (it) | 1994-05-13 |
IT1256387B true IT1256387B (it) | 1995-12-04 |
Family
ID=11364287
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ITMI922604A IT1256387B (it) | 1992-11-13 | 1992-11-13 | Procedimento per preparare triazoloni |
Country Status (9)
Country | Link |
---|---|
US (1) | US5767275A (it) |
EP (1) | EP0668857B1 (it) |
AT (1) | ATE163414T1 (it) |
AU (1) | AU5464394A (it) |
DE (1) | DE69317122T2 (it) |
DK (1) | DK0668857T3 (it) |
ES (1) | ES2115916T3 (it) |
IT (1) | IT1256387B (it) |
WO (1) | WO1994011357A1 (it) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5625064A (en) * | 1995-04-19 | 1997-04-29 | Schering Corporation | Process for the preparation of triazolones |
CA2182241C (en) * | 1996-07-29 | 2002-09-17 | Bo Lei | Methods for the manufacture of nefazodone |
DE19816882A1 (de) * | 1998-04-17 | 1999-10-21 | Boehringer Ingelheim Pharma | Triazolone mit neuroprotektiver Wirkung |
ES2152860B1 (es) * | 1998-10-23 | 2001-08-16 | Finaf 92 Sa | Forma cristalina de la nefazodona y procedimiento para su preparacion. |
JP2002541191A (ja) | 1999-04-09 | 2002-12-03 | セプラコール, インク. | R−ヒドロキシネファゾドン |
EP1189616A2 (en) | 1999-04-09 | 2002-03-27 | Sepracor Inc. | S-hydroxynefazodone |
US9505728B2 (en) | 2012-03-09 | 2016-11-29 | Inception 2, Inc. | Triazolone compounds and uses thereof |
BR112015013350B1 (pt) | 2012-12-20 | 2022-04-05 | Tempest Therapeutics, Inc | Composto ou sal farmaceuticamente aceitável do mesmo, composição farmacêutica e respectivos usos |
KR20160048988A (ko) | 2013-09-06 | 2016-05-04 | 인셉션 2 인코퍼레이티드 | 트라이아졸론 화합물 및 이의 용도 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE1545646B1 (de) * | 1965-12-15 | 1969-09-18 | Boehringer Sohn Ingelheim | 1,3-Dimethyl-4-(2',4'-dichlorphenyl)-1,2,4-triazolon-(5) und Verfahren zu dessen Herstellung |
IT1052119B (it) * | 1972-10-16 | 1981-06-20 | Sigma Tau Ind Farmaceuti | Derivati del triazolinone e procedimento per la loro preparazione |
US4338317A (en) * | 1981-03-16 | 1982-07-06 | Mead Johnson & Company | Phenoxyethyl-1,2,4,-triazol-3-one antidepressants |
US4596884A (en) * | 1983-11-30 | 1986-06-24 | Bristol-Myers Company | 4-(2-phenoxyethyl)-1,2,4-triazolone process intermediates |
US5094683A (en) * | 1988-05-09 | 1992-03-10 | Bayer Aktiengesellschaft | Sulphonylaminocarbonyltriazolinones |
-
1992
- 1992-11-13 IT ITMI922604A patent/IT1256387B/it active IP Right Grant
-
1993
- 1993-11-06 ES ES94900112T patent/ES2115916T3/es not_active Expired - Lifetime
- 1993-11-06 AT AT94900112T patent/ATE163414T1/de active
- 1993-11-06 WO PCT/EP1993/003119 patent/WO1994011357A1/en active IP Right Grant
- 1993-11-06 DE DE69317122T patent/DE69317122T2/de not_active Expired - Lifetime
- 1993-11-06 US US08/424,477 patent/US5767275A/en not_active Expired - Lifetime
- 1993-11-06 EP EP94900112A patent/EP0668857B1/en not_active Expired - Lifetime
- 1993-11-06 DK DK94900112T patent/DK0668857T3/da active
- 1993-11-06 AU AU54643/94A patent/AU5464394A/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
AU5464394A (en) | 1994-06-08 |
WO1994011357A1 (en) | 1994-05-26 |
DK0668857T3 (da) | 1998-12-07 |
EP0668857B1 (en) | 1998-02-25 |
ITMI922604A0 (it) | 1992-11-13 |
ATE163414T1 (de) | 1998-03-15 |
US5767275A (en) | 1998-06-16 |
ES2115916T3 (es) | 1998-07-01 |
EP0668857A1 (en) | 1995-08-30 |
DE69317122T2 (de) | 1998-09-24 |
DE69317122D1 (de) | 1998-04-02 |
ITMI922604A1 (it) | 1994-05-13 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
0001 | Granted | ||
TA | Fee payment date (situation as of event date), data collected since 19931001 |
Effective date: 19971126 |